Air pollution may increase the sleep apnea severity:A nationwide analysis of smart device-based monitoring

作     者：Qingli Zhang Hong Wang Xinlei Zhu Anni Li Cong Liu Yutao Guo Haidong Kan Renjie Chen 

作者机构：School of Public HealthShanghai Institute of Infectious Disease and BiosecurityKey Lab of Public Health Safety of the Ministry of Education and NHC Key Lab of Health Technology AssessmentFudan UniversityShanghai 200032China Minitry of Education-Shanghai Key Laboratory of Children's Environmental HealthXinhua Hospital ffliated to Shanghai Jiao Tong University School of MedicineShanghai 200092China Sixth Medical CenterChinese PL A General HospitalBejing 100048China Chinese PLA Medical CollegeBeijing 100039China Shanghai Institute of Pollution Control and Ecological SecurityShanghai 200092China 

出 版 物：《The Innovation》 (创新（英文）)

年 卷 期：2023年第4卷第6期

页      面：69-75页

核心收录：

学科分类：1002[医学-临床医学] 100213[医学-耳鼻咽喉科学] 10[医学] 

基　　金：National Key Research and Development Program(2022YFC3702701) National Natural Science Foundation of China(92043301 and 82170309) Shanghai Committee of Science and Technology(21TQ015) 

主　　题：severity sleep pollution 

摘      要：Obstructive sleep apnea(OSA)can lead to sleep deprivation,accidents,and cardiovascular ***,research on the short-term effects of air pollutants on OSA severity is limited and *** conducted a novel case time series analysis using a nationwide dataset among Huawei smart device users to assess the association between air pollution and OSA severity in a population at moderate-to-severe risk of ***-effects regression models were used to assess the associations between air pollution and the risk of OSA exacerbation,apnea-hypopnea index(AH),and oxygen saturation.A total of 51,842 participants who were at moder-ate-tosevere risk of OSA(mean age[SD]:45.4[11.0],95.5%male)were included,with 6,232,056 person-days of *** as sociations of fine particulate matter,nitrogen dioxide,carbon monoxide,and sulfur dioxide with OSA severity could occur during the sleep period,and last for 2 *** increase of 1 interquartile range in the moving average concentrations of air pollution during the sleep period and the 2 previous days was associated with a 1.14%-4.31%increase in the risk of OSA exacerbation,an increase in AHI by 0.05-0.17 events/h,and a decrease in oxygen saturation(%)by *** exposure-response curves were almost *** associations between air pollutants and OSA were consistently stronger in participants aged 45 years or *** virtue of the smart device-based technology,this largescale,nationwide,longitudinal study provides compelling evidence that short-term exposure to air pollution may worsen sleep *** findings highlight the significance of ongoing efforts to improve air quality in mitigating OSA severity and the relevant disease burden in an aging era.