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Stability in the Shephard Problem for L_p-Projection of Convex Bodies

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Wuhan University Journal of Natural Sciences 2014年第4期19卷 283-288页

作者： li xinhong MA Tongyi College of Mathematics and Statistics Northwest Normal University College of Mathematics and Statistics Hexi University

In this article, we study the convex bodies associated with Lp-projections in the Brunn-Minkowski-Firey theory, and apply the Fourier analytic methods to prove the linear stability in the Shephard problem for Lp-proje... 详细信息

关键词： stability convex bodies Lp-projections Fouriertransform

C60 Fullerenes Suppress Reactive Oxygen Species Toxicity Damage in Boar Sperm

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Nano-Micro Letters 2019年第4期11卷 817-833页

作者： xinhong li lirui Wang Huan liu Jieli Fu linqing Zhen Yuhua li Yaozhong Zhang Yafei Zhang Shanghai Key Laboratory of Veterinary Biotechnology School of Agriculture and BiologyShanghai Jiao Tong UniversityShanghai 200240People’s Republic of China Institute of Nano Biomedicine and Engineering Shanghai Engineering Research Centre for Intelligent Diagnosis and Treatment InstrumentDepartment of Instrument Science and EngineeringSchool of Electronic Information and Electrical EngineeringShanghai Jiao Tong UniversityShanghai 200240People’s Republic of China Department of Electrical and Computer Engineering Michigan State UniversityEast LansingUSA Key Laboratory of Thin Film and Microfabrication(Ministry of Education) Department of Micro/Nano ElectronicsSchool of ElectronicsInformation and Electrical EngineeringShanghai Jiao Tong UniversityShanghai 200240People’s Republic of China

We report the carboxylated C60 improved the survival and quality of boar sperm during liquid storage at 4°C and thus propose the use of carboxylated C60 as a novel antioxidant semen extender *** results demonstrated that the sperm treated with 2μg mL?1 carboxylated C60 had higher motility than the control group(58.6%and 35.4%,respectively;P?0.05).Moreover,after incubation with carboxylated C60 for 10 days,acrosome integrity and mitochondrial activity of sperm increased by 18.1%and 34%,respectively,compared with that in the control ***,the antioxidation abilities and adenosine triphosphate levels in boar sperm treated with carboxylated C60 significantly increased(P?0.05)compared with those in the control *** presence of carboxylated C60 in semen extender increases sperm motility probably by suppressing reactive oxygen species(ROS)toxicity ***,carboxylated C60 could protect boar sperm from oxidative stress and energy deficiency by inhibiting the ROS-induced protein dephosphorylation via the cAMP-PKA signaling *** addition,the safety of carboxylated C60 as an alternative antioxidant was also comprehensively evaluated by assessing the mean litter size and number of live offspring in the carboxylated C60 treatment *** findings confirm carboxylated C60 as a novel antioxidant agent and suggest its use as a semen extender supplement for assisted reproductive technology in domestic animals.

关键词： Carboxylated C60 Semen preservation Oxidative stress Motility Protein dephosphorylation

DTBVis:An interactive visual comparison system for digital twin brain and human brain

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Visual Informatics 2023年第2期7卷 41-53页

作者： Yuxiao li xinhong li Siqi Shen Longbin Zeng Richen liu Qibao Zheng Jianfeng Feng Siming Chena School of Data Science Fudan UniversityChina Institute of Science and Technology for Brain-Inspired Intellignece Fudan UniversityChina School of Computer and Electronic Information Nanjing Normal UniversityChina

The digital twin brain(DTB)computing model from brain-inspired computing research is an emerging artificial intelligence technique,which is realized by a computational modeling approach of hardware and *** can achieve various cognitive abilities and their synergistic mechanisms in a manner similar to the human *** that the task of the DTB is to simulate the functions of the human brain,comparing the similarities and differences between the two is ***,the visualization study of the DTB is still ***,the complexity of the datasets(multilevel spatiotemporal granularity and different types of comparison tasks)presents new challenges to the analysis and exploration of ***,in this study,we proposed DTBVis,a visual analytics system that supports comparison tasks for the *** supports iterative explorations from different levels and at different *** with automatic similarity recommendation,and high-dimensional exploration,DTBVis can assist experts in understanding the similarities and differences between the DTB and the human brain,thus helping them adjust their model and enhance its *** highest level of DTBVis shows an overview of the datasets from the brain,which is used for comparison and exploration of the function and structure of the DTB and the human *** medium level is used for the comparison and exploration of a designated brain *** low level can analyze a designated brain *** worked closely with experts of brain science and held regular seminars with *** from the experts indicates that our approach helps them conduct comparative studies of the DTB and human brain and make modeling adjustments of the DTB through intuitive visual comparisons and interactive explorations.

关键词： Brain Digital twin brain Visual analytics Comparative analysis

Biomimetic Integrated Nanozyme for Flare and Recurrence of Gouty Arthritis

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Asian Journal of Pharmaceutical Sciences 2024年第3期19卷 131-145页

作者： Rui Wang Tongyao liu xinhong li Enhao Lu Yiting Chen Kuankuan Luo Tao Wang Xueli Huang Zhiwen Zhang Shilin Du Xianyi Sha Key Laboratory of Smart Drug Delivery(Ministry of Education) Institutes of Integrative MedicineDepartment of PharmaceuticsSchool of PharmacyFudan UniversityShanghai 201203China Department of Emergency Medicine Shanghai Geriatric Medical CenterShanghai 201104China Department of Emergency Medicine Zhongshan HospitalFudan UniversityShanghai 200032China

Flare and multiple recurrences pose significant challenges in gouty *** treatments provide temporary relief from inflammation but fail to promptly alleviate patient pain or effectively prevent subsequent *** should also be noted that both anti-inflammation and metabolism of uric acid are necessary for gouty arthritis,calling for therapeutic systems to achieve these two goals *** this study,we propose a biomimetic integrated nanozyme,HMPB-Pt@MM,comprising platinum nanozyme and hollow Prussian *** demonstrates anti-inflammatory properties by eliminating reactive oxygen species and reducing infiltration of inflammatory ***,it rapidly targets inflamed ankles through the camouflage of macrophage ***,HMPB-Pt@MM exhibits urate oxidase-like capabilities,continuously metabolizing locally elevated uric acid concentrations,ultimately inhibiting multiple recurrences of gouty *** summary,HMPB-Pt@MM integrates ROS clearance with uric acid metabolism,offering a promising platform for the treatment of gouty arthritis.

关键词： Gouty arthritis Inflammation Nanozyme Platinum Prussian blue

Synthesis of Glucoside Compounds of Ferrocenyl Phenols and Their Antianemic Activity

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Wuhan University Journal of Natural Sciences 1998年第1期3卷 81-85页

作者： liu Huiying, Chen Yong, Zhao Hongxing, li xinhong,li Baorui (Department of Chemistry, Wuhan University, Wuhan 430072, China)Zeng Fanbo, Cui Xiaorui(Department of Pharmacy, Tongji Medical University, Wuhan 430030, China) Wuhan University Department of Chemistry Wuhan China (GRID:grid.49470.3e) (ISNI:***) Tongji Medical University Department of Pharmacy Wuhan China (GRID:grid.33199.31) (ISNI:***)

Six glucoside compounds have been synthesized by means of phase-transfer catalytic method and deacetylation from the starting material ferrocene. Their structures have been confirmed by elementary analysis, IR,1HNMR and MS. The antianemic activities of some compounds have also been tested. Results indicate that these glucoside compounds possess the antianemic activities and therefore, the further study is well worth making.

关键词： Key words ferrocenyl phenol glucosidic bond antianemic activity ferrocenyl derivatives organometal glucoside compound

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苏里格气田苏20井区废弃地层压力研究

油气井测试 2010年第2期19卷 22-23页

作者：李忻洪西南石油大学石油工程学院四川新都610500

苏里格气田是典型的低渗透气田,要准确计算其采收率和可采储量,必需确定气井的废弃条件。从对苏里格气田认识程度出发,采用经验公式法、气藏埋深法,以及经济—产能方程—井底流压法,计算苏里格气田苏20井区废弃地层压力,旨在为气田开发... 详细信息

苏里格气田是典型的低渗透气田,要准确计算其采收率和可采储量,必需确定气井的废弃条件。从对苏里格气田认识程度出发,采用经验公式法、气藏埋深法,以及经济—产能方程—井底流压法,计算苏里格气田苏20井区废弃地层压力,旨在为气田开发方案设计提供依据。

关键词：气藏埋深经济极限产量产能方程废弃地层压力苏里格气田

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局部晚期头颈部鳞癌治疗进展

中华放射肿瘤学杂志 2024年第1期33卷 72-78页

作者：杨兴龙李心红内蒙古医科大学附属医院呼和浩特010059 内蒙古医科大学附属医院放疗科呼和浩特010059

局部晚期头颈部鳞癌目前常规的治疗方案是同步放化疗,但是患者5年生存率仍然不高。近年来放疗技术的发展,为患者提供了更多的选择。而且随着人们生活水平的提高,越来越多的患者更加关注生活质量。目前急需探究更好的综合治疗方案以改善... 详细信息

局部晚期头颈部鳞癌目前常规的治疗方案是同步放化疗,但是患者5年生存率仍然不高。近年来放疗技术的发展,为患者提供了更多的选择。而且随着人们生活水平的提高,越来越多的患者更加关注生活质量。目前急需探究更好的综合治疗方案以改善患者的预后。本文就局部晚期头颈部鳞癌的综合治疗进展做一综述。

关键词：头颈鳞癌,局部晚期诱导化疗免疫疗法凋亡抑制蛋白放射疗法

基于Adaboost的填充式防护结构超高速撞击损伤预测

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北京航空航天大学学报 2019年第1期45卷 149-158页

作者：丁文哲李新洪杨虹航天工程大学研究生院北京101416 航天工程大学宇航科学与技术系北京101416

填充式防护结构的显式弹道极限方程在对弹丸进行超高速撞击损伤预测时,由于填充材料、填充方式的不同,会导致预测结果与实测数据存在一定偏差。对此,采用机器学习方式将该问题转化为二分类问题,以碰撞过程中的弹丸撞击参数、防护结构参... 详细信息

填充式防护结构的显式弹道极限方程在对弹丸进行超高速撞击损伤预测时,由于填充材料、填充方式的不同,会导致预测结果与实测数据存在一定偏差。对此,采用机器学习方式将该问题转化为二分类问题,以碰撞过程中的弹丸撞击参数、防护结构参数作为分类特征,构建了基于Adaboost的填充式防护结构超高速撞击损伤预测模型。该模型以分类回归树(CART)作为弱分类器,通过对一系列弱分类器的加权组合生成强分类器,并通过对训练样本的循环使用,实现了小样本集下的撞击损伤预测。实验结果表明,建立的Adaboost预测模型对填充式防护结构的超高速撞击损伤具有良好的预测效果,总体预测率与安全预测率相比于NASA的弹道极限方程均提高了14. 3%,具有更强的通用性。通过不同训练样本规模下的交叉检验,证明了该模型具有良好的鲁棒性与准确性。

关键词：填充式防护结构损伤研究 Adaboost算法总体预测率安全预测率

纳米二氧化硅粒子对聚氯乙烯膜的表面结构及浸润性能的调控作用

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高分子学报 2005年第5期15卷 740-744页

作者：李新红马永梅王佛松中国科学院化学研究所北京100080

报道了一种简便的调控聚合物材料表面结构及浸润性能的方法.利用流延成膜和纳米二氧化硅粒子的印迹修饰作用,制备出3种具有不同表面结构的聚氯乙烯(PVC)膜,膜的浸润性能表现为与水的接触角从103°的疏水性变为65°的亲水性,再改变至130... 详细信息

报道了一种简便的调控聚合物材料表面结构及浸润性能的方法.利用流延成膜和纳米二氧化硅粒子的印迹修饰作用,制备出3种具有不同表面结构的聚氯乙烯(PVC)膜,膜的浸润性能表现为与水的接触角从103°的疏水性变为65°的亲水性,再改变至130°的疏水性.扫描电镜结果表明印迹修饰后的PVC膜具有纳米和微米尺寸的凹凸表面结构.通过对比实验证实了溶剂氯仿和NaOH溶液并不影响膜表面的疏水性能.

关键词：聚氯乙烯膜纳米二氧化硅粒子表面结构浸润性能调控作用亲水性疏水性能运动特性