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Steady-state model for predicting size-resolved gas-particle partitioning of semi-volatile organic compounds (SVOCs) in indoor environments

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Building Simulation 2023年第3期16卷 443-460页

作者： Jianping Cao Yu Han Yujie Zhu Xingyu Duan Luyang Wang Haibao Huang School of Environmental Science and Engineering Sun Yat-sen UniversityGuangzhou 510006China Guangdong Provincial Key Laboratory of Environmental Pollution Control and Remediation Technology Guangzhou 510006China Department of Building Science Tsinghua UniversityBeijing 100084China

Semi-volatile organic compounds(SVOCs)are ubiquitous and important pollutants in indoor environments.The strong partition between gas phase and suspended particles has significant effects on the transport,human exposure via inhalation,and control strategies of indoor SVOCs.Several models have been developed to simulate the gas–particle partitioning of indoor SVOCs,including a steady-state model by expanding the steady-state model suitable for the outdoor environment to indoor environments.However,the effects of two important indoor environment-specific parameters,i.e.,the particle size distribution(PSD)and the air-change rate(ACH),were not considered in the existing steady-state model,leading to the inaccurate predictions among buildings.To solve this problem,this study developed a novel steady-state model to more comprehensively simulate the gas-particle partitioning of indoor SVOCs by incorporating the effects of PSD and ACH.Better agreement between the predictions of the novel model and the results collected via both field tests and laboratory tests(retrieved from two different studies)supported the effectiveness of the improvements in the novel model.Sensitivity analysis further supported the necessity of involving PSD and ACH.Further implications of the novel model were also discussed.This study should be helpful for deepening the understanding and accurate simulation of the gas-particle partitioning,as well as the transport and human exposure via inhalation,of indoor SVOCs.

关键词： indoor air quality airborne particles particle size distribution ventilation mass transfer analysis

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Constructing the bonding between conductive agents and active materials/binders stabilizes silicon anode in Lithium-ion batteries

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Journal of Energy Chemistry 2023年第5期80卷 23-31,I0002页

作者： Jie Tang Jiawang Zhou Xingyu Duan Yujie Yang Xinyi Dai Fuzhong Wu Guizhou High-level Institution Key Laboratory of High-Performance Battery Materials Guizhou UniversityGuiyang 550025GuizhouChina

Silicon(Si)anode has been considered a promising candidate due to its remarkable theoretical capacity but it was plagued by severe pulverization because of the inherent huge volume variation.Enhancing electrode stability is an effective approach to improve electrochemical performance.Herein,a stable Si anode was established by an innovative construction of the bonding between conductive agents and active materials/binders.As a result,the strong interaction of electrode components not only effectively alleviates the volume expansion of Si but also achieves a stable interface by generating the beneficial solid electrolyte interphase(SEI)composition.Attributed to the deliberate scheme of the electrode,the Si anode exhibits sterling electrochemical performance.Besides,the device of the electrode is not only effective for other binders but also for other anode materials with high volume variation,thus shedding light on the rational design of electrodes for high-energy-density lithium-ion batteries.

关键词： Lithium-ion batteries Si MXene SEI Structural stability

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Observational evidences of wave excitation and inverse cascade in a distant Earth foreshock region

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Science China Earth Sciences 2019年第4期62卷 619-630页

作者： Jiansen HE Die duan xingyu ZHU Limei YAN Linghua WANG School of Earth and Space Sciences Peking University Key Laboratory of Earth and Planetary Physics Institute of Geology and Geophysics Chinese Academy of Sciences

The foreshock with nascent plasma turbulence is regarded as a fascinating region to understand basic plasma physical processes, e.g., wave-particle interactions as well as wave-wave couplings. Although there have been plenty of intensive studies on this topic, some key clues about the physical processes still lack observations. A relatively comprehensive case study with some new observations is presented in this work based on the WIND spacecraft observations. In this case, upstream energetic protons were drifting at tens of Alfvén speed with respect to the background plasma protons. When looking at the magnetic wave activities, we find the co-existence of high-frequency(0.1-0.5 Hz) large-amplitude right-hand polarized(RHP) waves and lowfrequency(0.02-0.1 Hz) small-amplitude left-hand polarized(LHP) waves in the spacecraft(SC) frame. The observed anticorrelation between magnetic and velocity fluctuations along with the sunward magnetic field direction indicates that the lowfrequency LHP waves in the SC frame are in fact the sunward upstream RHP Alfvénic waves in the solar wind frame. This new observation corroborates the applicability of theories about plasma non-resonance instability and inverse cascade to the foreshock region, where the downstream high-frequency RHP parent waves are excited by the upstream energetic protons through non-resonance instability and the low-frequency RHP daughter waves are generated by the parent waves due to nonlinear parametric instability. Furthermore, enhanced downstream energetic proton fluxes are inferred to result from scattering of the upstream protons by the nascent turbulent fluctuations. Therefore, some critical clues about the newborn turbulence in the foreshock are provided in this work.

关键词： Solar wind Foreshock Wave-particle interaction Parametric instability

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Tumor Microenvironment-Adaptive Nanoplatform Synergistically Enhances Cascaded Chemodynamic Therapy

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Bioactive Materials 2023年第4期22卷 239-253页

作者： Yuemin Wang duan Wang Yuyue Zhang Hong Xu Luxuan Shen Jing Cheng Xinyuan Xu Hong Tan xingyu Chen Jianshu Li College of Polymer Science and Engineering State Key Laboratory of Polymer Materials EngineeringSichuan UniversityChengdu610065China Orthopedic Research Institution Department of OrthopedicsWest China HospitalSichuan UniversityChengdu610041China College of Medicine Southwest Jiaotong UniversityChengdu610003China State Key Laboratory of Oral Diseases West China Hospital of StomatologyMed-X Center for MaterialsSichuan UniversityChengdu610041China

Chemodynamic therapy(CDT),a noninvasive strategy,has emerged as a promising alternative to conventional chemotherapy for treating tumors.However,its therapeutic effect is limited by the amount of H_(2)O_(2),pH value,the hypoxic environment of tumors,and it has suboptimal tumor-targeting ability.In this study,tumor cell membrane-camouflaged mesoporous Fe_(3)O_(4) nanoparticles loaded with perfluoropentane(PFP)and glucose oxidase(GOx)are used as a tumor microenvironment-adaptive nanoplatform(M-mFeP@O_(2)-G),which synergistically enhances the antitumor effect of CDT.Mesoporous Fe_(3)O_(4) nanoparticles are selected as inducers for photothermal and Fenton reactions and as nanocarriers.GOx depletes glucose within tumor cells for starving the cells,while producing H2O2 for subsequent⋅OH generation.Moreover,PFP,which can carry O_(2),relieves hypoxia in tumor cells and provides O_(2) for the cascade reaction.Finally,the nanoparticles are camouflaged with osteosarcoma cell membranes,endowing the nanoparticles with homologous targeting and immune escape abilities.Both in vivo and in vitro evaluations reveal high synergistic therapeutic efficacy of M-mFeP@O_(2)-G,with a desirable tumor-inhibition rate(90.50%),which indicates the great potential of this platform for clinical treating cancer.

关键词： Chemodynamic therapy Tumor microenvironment Cell membranes Homologous targeting Perfluoropentane Glucose oxidase

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品牌标志对听障人群消费决策的影响研究

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全国流通经济 2022年第2期 13-15页

作者：段兴禹南京特殊教育师范学院美术与设计学院江苏南京210038

品牌是塑造企业形象的重要载体,品牌标志的符号元素,能够呈现出企业文化、产品内容,是消费者认知企业产品的重要窗口。听障人群对于品牌产品的认知存在缺陷,这就导致其在消费中缺乏“安全感”,影响消费决策的形成。品牌标志是视觉感知... 详细信息

品牌是塑造企业形象的重要载体,品牌标志的符号元素,能够呈现出企业文化、产品内容,是消费者认知企业产品的重要窗口。听障人群对于品牌产品的认知存在缺陷,这就导致其在消费中缺乏“安全感”,影响消费决策的形成。品牌标志是视觉感知的重要元素,对于听障人群而言,是其消费决策的重要前提条件。本文立足消费决策研究,围绕听障人群的特殊特性,在研究综述中分析了品牌标志对其消费决策的影响关系,并基于分析结果,提出企业在经营发展中应夯实品牌建设、建立品牌情感、提升品牌力,以丰富饱满的品牌标志促进听障群体消费决策的生成。

关键词：品牌标志听障人群消费决策影响

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Propagation and Evolution of MHD Waves in Fast and Slow Solar Wind in Inner Heliosphere

Propagation and Evolution of MHD Waves in Fast and Slow Sola...

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2022年中国地球科学联合学术年会

作者： Jiansen He Liping Yang Die duan xingyu Zhu Chuanpeng Hou Peking University

The detection of MHD waves by Parker Solar Probe in the primary slow solar wind near the Sun has given rise to great concern to the wave/turbulence-driven scenario of solar wind origin. One of the open key questions is, how do MHD waves propagate and evolve differently in the fast and slow solar wind streams, respectively? To study this problem, we simulate the formation of high and low-speed solar wind and the propagation of evolving Alfvén waves therein from a global perspective.

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Collagen triple helix repeat containing-1 promotes functional recovery of sweat glands by inducing adjacent microvascular network reconstruction in vivo

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Burns & Trauma 2022年第1期10卷 387-400页

作者： xingyu Yuan Xianlan duan Zhao Li Bin Yao Enhejirigala Wei Song Yi Kong Yuzhen Wang Fanliang Zhang Liting Liang Shijun Zhu Mengde Zhang Chao Zhang Sha Huang Xiaobing Fu School of Medicine Nankai University94 Wei Jin RoadTianjin 300071PR China Research Center for Tissue Repair and Regeneration affiliated to the Medical Innovation Research Department PLA General Hospital28 Fu Xing RoadBeijing 100853PR China PLA Key Laboratory of Tissue Repair and Regenerative Medicine and Beijing Key Research Laboratory of Skin Injury Repair and RegenerationChinese PLA General Hospital and PLA Medical College51 Fu Cheng RoadBeijing 100048PR China Research Unit of Trauma Care Tissue Repair and RegenerationChinese Academy of Medical Sciences2019RU051Beijing 100048PR China Academy of Medical Engineering and Translational Medicine Tianjin University92 Weijin RoadTianjin300072PR China College of Graduate Tianjin Medical UniversityTianjin 300070PR China Institute of Basic Medical Research Inner Mongolia Medical UniversityHohhot 010110Inner MongoliaPR China Department of Burn and Plastic Surgery Air Force Hospital of Chinese PLA Central Theater CommandDatong 037000ShanxiPR China

Background:Sweat glands(SGs)have low regenerative potential after severe burns or trauma and their regeneration or functional recovery still faces many obstacles.In practice,restoring SG function requires not only the structural integrity of the gland itself,but also its neighboring tissues,especially blood vessels.Collagen triple helix repeat containing-1(CTHRC1)was first identified in vascular repair,and increasing reports showed a close correlation between cutaneous appendage specification,patterning and regeneration.The purpose of the present study was to clarify the role of CTHRC1 in SGs and their adjacent microvessels and find therapeutic strategies to restore SG function.Methods:The SGs and their adjacent microvascular network of Cthrc^(1−/−)mice were first inves-tigated using sweat test,laser Doppler imaging,tissue clearing technique and transcriptome analysis.The effects of CTHRC1 on dermal microvascular endothelial cells(DMECs)were further explored with cell proliferation,DiI-labeled acetylated low-density lipoprotein uptake,tube for-mation and intercellular junction establishment assays.The effects of CTHRC1 on SG function restoration were finally confirmed by replenishing the protein into the paws of Cthrc(1−/−)mice.Results:CTHRC1 is a key regulator of SG function in mice.At the tissue level,Cthrc1 deletion resulted in the disorder and reduction of the microvascular network around SGs.At the molecular level,the knockout of Cthrc1 reduced the expression of vascular development genes and functional proteins in the dermal tissues.Furthermore,CTHRC1 administration considerably enhanced SG function by inducing adjacent vascular network reconstruction.Conclusions:CTHRC1 promotes the development,morphogenesis and function execution of SGs and their neighboring vasculature.Our study provides a novel target for the restoration or regeneration of SG function in vivo.

关键词： Collagen triple helix repeat containing-1 Sweat glands Microvascular network Dermalmicrovascular endothelial cells Reconstruction

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The role of CTHRC1 in promotion of cutaneous wound healing

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Signal Transduction and Targeted Therapy 2022年第7期7卷 2144-2147页

作者： Xianlan duan xingyu Yuan Bin Yao Wei Song Zhao Li Enhejirigala Yi Kong Yuzhen Wang Xiaobing Fu Sha Huang School of Medicine NanKai University94 Wei Jin RoadTianjin 300071People’s Republic of China Research Center for Tissue Repair and Regeneration affiliated to the Medical Innovation Research Department PLA General Hospital51 Fu Cheng RoadBeijing 100048People’s Republic of China Academy of Medical Engineering and Translational Medicine Tianjin University92 Weijin RoadTianjin 300072People’s Republic of China

Dear Editor,Wound healing after tissue injury is a well-orchestrated process involving various cell types,growth factors,and extracellular matrix(ECM)components.Collagen triple helix repeat containing1(CTHRC1),a secreted ECM protein,is transiently expressed in the repair process after arterial injury and myocardial infarction,1 regulating collagen matrix deposition and cell migration through TGF-βsignaling pathway.2 However,the expression and function of CTHRC1 during cutaneous wound repair remain largely undefined.We initially investigated the spatiotemporal expression of CTHRC1 during full-thickness cutaneous wound healing.By searching the GEO database,we found a transcriptome dataset(GSE23006),which analyzed the gene expression of mouse skin wounds from day 0 to day 10,spanned all stages of the wound healing process.

关键词： healing wound arterial

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Reciprocal interaction between vascular niche and sweat gland promotes sweat gland regeneration

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Bioactive Materials 2023年第3期21卷 340-357页

作者： xingyu Yuan Xianlan duan Enhejirigala Zhao Li Bin Yao Wei Song Yuzhen Wang Yi Kong Shijun Zhu Fanliang Zhang Liting Liang Mengde Zhang Chao Zhang Deling Kong Meifeng Zhu Sha Huang Xiaobing Fu School of Medicine Nankai University94 Weijin RoadTianjin300071PR China Research Center for Tissue Repair and Regeneration Affiliated to the Medical Innovation Research Department PLA General Hospital28 Fuxing RoadBeijing100853PR China PLA Key Laboratory of Tissue Repair and Regenerative Medicine and Beijing Key Research Laboratory of Skin Injury Repair and RegenerationChinese PLA General Hospital and PLA Medical College51 Fucheng RoadBeijing100048PR China College of Graduate Tianjin Medical UniversityTianjin300070PR China Institute of Basic Medical Research Inner Mongolia Medical UniversityHohhot010110Inner MongoliaPR China Academy of Medical Engineering and Translational Medicine Tianjin University92 Weijin RoadTianjin300072PR China Department of Burn and Plastic Surgery Air Force Hospital of Chinese PLA Central Theater CommandDatong037000ShanxiPR China College of Life Science State Key Laboratory of Medicinal Chemical BiologyKey Laboratory of Bioactive Materials of Ministry of EducationNankai University94 Weijin RoadTianjin300071PR China Research Unit of Trauma Care Tissue Repair and RegenerationChinese Academy of Medical Sciences2019RU051Beijing100048PR China

The incorporation of vasculature is known to be effective in tissue or organ functional regeneration.However,a vague understanding of the interaction between epidermal appendages and their vascular niches is a foremost obstacle to obtaining sweat gland(SG)-specific vasculature units.Here,we map their precise anatomical con-nections and report that the interplay between SG cells(SGCs)and the surrounding vascular niche is key for glandular development and homeostasis maintenance.To replicate this interplay in vitro,we used three-dimensional(3D)bioprinting to generate reproducible SGC spheroids from differentiated adipose-derived mesenchymal stem cells(ADSCs).With dermal microvascular endothelial cells(DMECs),sacrificial templates made from poly(ε-caprolactone)(PCL)were fabricated to pattern the vascular niche.This interplay model promoted physiologically relevant vascularized glandular morphogenesis in vitro and in vivo.We identified a reciprocal regulatory mechanism for promoting SGs regeneration via contact-independent cell communication and direct cell-cell interactions between SGs and the vasculature.We envision the successful use of our approach for vascularized organ regeneration in the near future.

关键词： Vascular niche 3D bioprinting Sweat gland-vasculature interaction model ECM scaffold Sweat gland regeneration

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乡村振兴下留守儿童户外空间景观设计研究

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丝网印刷 2023年第12期 103-105页

作者：段星宇桂垚景德镇陶瓷大学江西科技师范大学

基于马斯洛的需求层次理论,提出了注重科技互动、强调以人为本、加强趣味设计、融入地域文化、增强艺术表达的景观设计策略,为留守儿童户外活动空间景观设计提供借鉴。

关键词：留守儿童户外活动空间景观设计需求

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