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Data-driven mapping-relationship mining between hardness and mechanical properties of dual-phase titanium alloys via random forest and statistical analysis

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Rare Metals 2024年第2期43卷 829-841页

作者： Hai-Chao gong Qun-Bo Fan Hong-Mei zhang Xing-Wang Cheng Wen-Qiang Xie Kai Chen Lin Yang Jun-Jie zhang Bing-Qiang {3. Shun Xu school of Materials Science and Engineering Beijing Institute of TechnologyBeijing100081China National Key Laboratory of Science and Technology on Materials Under Shock and Impact Beijing100081China beijing Institute of Technology Chongqing Innovation Center Chongqing401135China Department of Mechanical and Materials Engineering University of Nebraska-LincolnLincolnNE68588USA

In order to accelerate the research on the property optimization of titanium alloy based on high-throughput methods,it is necessary to reveal the relationship between hardness and other mechanical properties which is still *** this work,taking Ti2.C alloy as research object,almost all the microstructure of dual-phase titanium alloys were covered by traversing over 100 heat treatment ***,massive experiments including microstructure characterization and performance test were conducted,obtaining 51,590 pieces of microstructure data and 3.91 pieces of mechanical property ***,based on large-scale data-driven technology,the quantitative mapping relationship between hardness and other mechanical properties was deeply *** results of random forest models showed that the correlation between hardness(H)and Charpy impact energy(A_(k))(or elongation,A)was hardly dependent on the microstructure types,while the relationship between H and tensile strength(R_(m))(or yield strength,R_(p0.2.)was highly dependent on microstructure ***,combined with statistical analysis,it was found that the relationship between H and Ak(or A)were negatively ***,the relationship between H and strength was positively linear for equiaxed microstructure,and strength was linked to d^(−1/2.(d,equivalent circle diameter)ofα-grains in the form of classical Hall–Petch formula;but for other microstructures,the relationships were ***,the above rules were nearly the same in the rolling direction and transverse ***,a"four-quadrant partition map"between H and R_(p0.2./R_(m) was established as a versatile material-screening tool,which can provide guidance for on-demand selection of titanium alloys.

关键词： Dual-phase titanium alloy Data-driven Hardness Mapping relationship

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Multiplexed stimulated emission depletion nanoscopy(mSTED)for 5-color live-cell long-term imaging of organelle interactome

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Opto-Electronic Advances 2024年第7期7卷 17-26页

作者： Yuran Huang Zhimin zhang Wenli Tao Yunfei wei Liang Xu Wenwen {2. Jiaqiang Zhou Liangcai Cao Yong Liu Yubing Han Cuifang Kuang Xu Liu State Key Laboratory of Extreme Photonics and Instrumentation College of Optical Science and EngineeringZhejiang UniversityHangzhou 310027China Research Center for Intelligent Chips and Devices Zhejiang LabHangzhou 311121China Wuhan National Laboratory for Optoelectronics Huazhong University of Science and TechnologyWuhan 430074China Department of Endocrinology and Metabolism Sir Run Run Shaw HospitalZhejiang University School of MedicineHangzhou 310016China Department of Precision Instruments Tsinghua UniversityBeijing 100084China College of electronics and information engineering Shanghai University of Electrical PowerShanghai 200090China ZJU-Hangzhou Global Scientific and Technological Innovation Center Hangzhou 311200China

Stimulated emission depletion microscopy(STED)holds great potential in biological science applications,especially in studying nanoscale subcellular ***,multi-color STED imaging in live-cell remains challenging due to the limited excitation wavelengths and large amount of laser ***,we develop a multiplexed live-cell STED method to observe more structures simultaneously with limited photo-bleaching and *** separating live-cell fluorescent probes with similar spectral properties using phasor analysis,our method enables five-color live-cell STED imaging and reveals long-term interactions between different subcellular *** results here provide an avenue for understanding the complex and delicate interactome of subcellular structures in live-cell.

关键词： optical nanoscopy phasor analysis multicolor live cell imaging

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Genome-wide adenine N6-methylation map reveals epigenomic regulation of lipid accumulation in Nannochloropsis

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Plant Communications 2024年第3期5卷 106-122页

作者： Yanhai gong Qintao Wang Li wei Wensi Liang Lianhong Wang Nana Lv Xuefeng Du Jiashun {2. Chen Shen Yi Xin Luyang Sun Jian Xu Single-Cell Center CAS Key Laboratory of BiofuelsShandong Key Laboratory of Energy GeneticsQingdao Institute of Bioenergy and Bioprocess TechnologyChinese Academy of SciencesQingdaoChina Shandong Energy Institute QingdaoChina Qingdao New Energy Shandong Laboratory QingdaoChina University of chinese Academy of Sciences Beijing 100049China Laboratory for Marine Biology and Biotechnology Qingdao National Laboratory for Marine Science and TechnologyQingdao 266237China

Epigenetic marks on histones and DNA,such as DNA methylation at N6-adenine(6mA),play crucial roles in gene expression and genome maintenance,but their deposition and function in microalgae remain largely ***,we report a genome-wide 6mA map for the model industrial oleaginous microalga Nannochloropsis oceanica produced by single-molecule real-time *** in 0.1%of adenines,6mA sites are mostly enriched at the AGGYV motif,more abundant in transposons and 3. untranslated re-gions,and associated with active ***,6mA gradually increases in abundance along the direction of gene transcription and shows special positional enrichment near splicing donor and transcrip-tion termination *** expressed genes tend to show greater 6mA abundance in the gene body than do poorly expressed genes,indicating a positive interaction between 6mA and general transcription ***,knockout of the putative 6mA methylase NO08G002.0 by genome editing leads to changes in methylation patterns that are correlated with changes in the expression of molybdenum cofactor,sulfate transporter,glycosyl transferase,and lipase genes that underlie reductions in biomass and oil *** contrast,knockout of the candidate demethylase NO06G02.00 results in increased 6mA levels and reduced *** the epigenomic players and their roles in biomass productivity and lipid metabolism lays a foundation for epigenetic engineering of industrial microalgae.

关键词： adenine N6-methylation industrial oleaginous microalgae Nannochloropsis oceanica transcriptional regulation epigenomics

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Towards the insights into the deactivation behavior of acetylene hydrogenation catalyst

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Petroleum Science 2024年第2期21卷 1405-1414页

作者： Hai-Xia Su Yang Jiao Jian-gong Shi Zhi-wei Yuan Di {2. Xu-Peng Wang Jing Ren Dan Liu Jian-Zhou Gui Hai-Yang Gao Xiao-Li Xu State Key Laboratory of Separation Membranes&Membrane Processes Tianjin Key Laboratory of Green Chemical Technology and Process EngineeringSchool of Material Science and EngineeringTiangong UniversityTianjin300387China Institute of Engineering Technology Sinopec Catalyst Co.LtdBeijing101100China State Key Laboratory of Separation Membranes and Membrane Processes Tianjin Key Laboratory of Green Chemical Technology and Process EngineeringSchool of ChemistryTiangong UniversityTianjin300387China

A series of model catalysts were obtained by treating commercial fresh and spent catalysts unloaded from the factory with different methods, including green oil dipping, extraction and high-temperature regeneration;finally, the deactivation behavior of the commercial catalyst for acetylene hydrogenation were studied. The influence of various possible deactivation factors on the catalytic performance was elucidated via detailed structural characterization, surface composition analysis, and activity *** results showed that green oil, carbon deposit and sintering of active metal were the main reasons for deactivation, among which green oil and carbon deposit led to rapid deactivation, while the activity could be recovered after regeneration by high-temperature calcination. The sintering of active metal components was attributed to the high-temperature regeneration in hydrothermal conditions, which was slow but irreversible and accounted for permanent deactivation. Thus, optimizing the regeneration is expected to extend the service life of the commercial catalyst.

关键词： Acetylene Hydrogenation Green oil Carbon deposit Sintering Catalyst deactivation

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Significantly enhanced superconductivity in monolayer FeSe films on SrTiO3.001） via metallic δ-doping

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National Science Review 2024年第3期11卷 119-127页

作者： Xiaotong Jiao Wenfeng Dong Mingxia Shi Heng Wang Cui Ding Zhongxu wei Guanming gong Yanan Li Yuanzhao Li Binjie Zuo Jian Wang Ding {2. Minghu Pan Lili Wang Qi-Kun Xue State Key Laboratory of Low-Dimensional Quantum Physics Department of Physics Tsinghua University school of Physics&Information Technology Shaanxi Normal University beijing Academy of Quantum Information Sciences Department of Physics Southern University of Science and Technology International Center for Quantum Materials School of Physics Peking University Department of Physics The Pennsylvania State University Collaborative Innovation Center of Quantum Matter Hefei National Laboratory

Superconductivity transition temperature（Tc） marks the inception of a macroscopic quantum phase-coherent paired state in fermionic systems. For 2. superconductivity, the paired electrons condense into a coherent superfluid state at Tc, which is usually lower than the pairing temperature, between which intrinsic physics including Berezinskii–Kosterlitz–Thouless transition and pseudogap state are hotly debated. In the case of monolayer FeSe superconducting films on SrTiO3.001）, although the pairing temperature（Tp） is revealed to be 65–83.K by using spectroscopy characterization, the measured zero-resistance temperature（Tc0） is limited to 2. K. Here, we report significantly enhanced superconductivity in monolayer FeSe films by δ-doping of Eu or Al on SrTiO3.001） surface, in which Tc0is enhanced by 12.K with a narrowed transition width ΔTc～8 K, compared with non-doped samples. Using scanning tunneling microscopy/spectroscopy measurements, we demonstrate lowered work function of the δ-doped SrTiO3.001） surface and enlarged superconducting gaps in the monolayer FeSe with improved morphology/electronic homogeneity. Our work provides a practical route to enhance 2. superconductivity by using interface engineering.

关键词： monolayer FeSe interface superconductivity δ-doping zero-resistance temperature superconductivity transition temperature

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Science and Technology Is Not Simply Equal to Sci-Tech

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Genomics, Proteomics & Bioinformatics 2003年第2期1卷 87-89页

作者： xingmin ligraduate school, chinese Academy of Sciences,{2., {3. zhang (beijing Language and Culture University, beijing 100083. China) and wei gong (beijing Genomics Institute, beijing 1013.0, China) Graduate school Chinese Academy of Sciences Beijing 100039 China

The terms "science" (Hanyu Pinyin: Kexue) and "technology" (Jishu), in western languages, are usually used separately with different meanings or together as "science and technology". However, they are often mentioned as "Kexue Jishu", or even abbreviated as "sci-tech (Keji)" in China (It is used in a similar way in Japan). It not only causes great confusion in conceptual content, but also very misleading

关键词： that on as it Science and Technology Is Not Simply Equal to Sci-Tech for been into of

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Efficacy and safety of Jiawei Simiao powder combined with celecoxib for acute gouty arthritis:A meta-analysis

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Journal of Traditional chinese Medical Sciences 2024年第3期11卷 283-292页

作者： weiyu Jia Maoying wei Wenhua {2. Dan Yin Yijia Jiang Churan Wang Xiangdong Wang Yutong Fei Yanbing {3. Dongzhimen Hospital Beijing University of Chinese MedicineBeijing 100700China Nutrition and Cancer Biology Lab Jean Mayer USDA-Human Nutrition Research Center on Aging(HNRCA)at Tufts UniversityBoston 02111USA Centre for Evidence-Based chinese Medicine Beijing University of Chinese MedicineBeijing 100029China

Objective To evaluate the efficacy and safety of Jiawei Simiao powder(JWSMP)combined with celecoxib for the treatment of acute gouty arthritis by conducting a meta-analysis of randomized controlled trials(RCTs).Methods The chinese National Knowledge Infrastructure Databases,chinese Scientific Journal Database,Wanfang,Cochrane Library,EMBASE,PubMed,and Web of Science databases were searched from inception until December *** variables were analyzed using the mean difference(MD)for analysis,and dichotomous variables were used as risk *** with similar characteristics were pooled for meta-analysis,and heterogeneity was assessed using *** Cochrane Handbook was used to assess the risk of bias and *** 5.3.software was used to perform the *** Thirteen RCTs involving 1007 patients were included in the *** quality of the included studies was low(unclear randomization processes and insufficient blinding reporting).The group receiving JWSMP combined with celecoxib showed significantly lower levels of serum uric acid(SUA,MD=−66.3.3.95%confidence interval(CI):−80.97 to−51.67,P3. to−3.8{3.P3.,95%CI:−11.15,−3.63.P3.14,95%CI:−{3.4 to−1.88,P3.,95%CI:1.14 to 1.{3.,P<.001)and fewer adverse compared to celecoxib *** JWSMP combined with celecoxib is more effective than celecoxib alone in improving the total efficacy rate,alleviating joint pain,and improving SUA,ESR,and CRP *** also reduced the occurrence of adverse events caused by ***,the quality of the included studies was low,highlighting the need for further high-quality research with larger sample sizes and robust methodologies,such as double-blind randomization,to confirm these findings.

关键词： Jiawei Simiao powder Celecoxib Acute gouty arthritis Meta-analysis

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Genetic variation in a heat shock transcription factor modulates cold tolerance in maize

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Molecular Plant 2024年第9期17卷 1423-1438页

作者： Lei Gao Lingling Pan Yiting Shi Rong Zeng Minze Li Zhuoyang Li Xuan zhang Xiaoming Zhao Xinru gong {2. Huang Xiaohong Yang Jinsheng Lai Jianru Zuo Zhizhong gong Xiqing Wang {2.{2. Jin Zhaobin Dong Shuhua Yang State Key Laboratory of Plant Environmental Resilience Frontiers Science Center for Molecular Design BreedingCollege of Biological SciencesCenter for Crop Functional Genomics and Molecular BreedingChina Agricultural UniversityBeijing 100193China State Key Laboratory of Maize Bio-breeding National Maize Improvement CenterFrontiers Science Center for Molecular Design BreedingDepartment of Plant Geneticsand BreedingChinaAgricultural UniversityBeijingChina State Key Laboratory of Plant Genomics and National Plant Gene Research Center Institute of Genetics and Developmental BiologyChinese Academy of SciencesBeijing100101China

Understanding how maize(Zea mays)responds to cold stress is crucial for facilitating breeding programs of cold-tolerant *** extensive utilization of the genome-wide association study(GWAs)approach for exploring favorable natural alleles associated with maize cold tolerance,few studies have successfully identified candidate genes that contribute to maize cold *** this study,we used a diverse panel of inbred maize lines collected from different germplasm sources to perform a GWAS on var-iations in the relative injured area of maize true leaves during cold stress-a trait very closely correlated with maize cold *** identified HsF2.,which encodes a B-class heat shock transcription factor(HSF)that positively regulates cold tolerance at both the seedling and germination *** varia-tions in the promoter of the cold-tolerant HSF2.Hap1 allele led to increased HSF2. expression under cold stress by inhibiting binding of the basic leucine zipper bziP68 transcription factor,a negative regulator of cold *** integrating transcriptome deep sequencing,DNA affinity purification sequencing,and targeted lipidomic analysis,we revealed the function of HsF2. in regulating lipid metabolism homeo-stasis to modulate cold tolerance in *** addition,we found that HsF2. confers maize cold tolerance without incurring yield ***,this study establishes HsF2. as a key regulator that en-hances cold tolerance in maize,providing valuable genetic resources for breeding of cold-tolerant maize varieties.

关键词： heat shock factor HSF2. cold tolerance natural variation bZiP68 lipid metabolism maize

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Portable fluorogenic probe for monitoring of volatile amine vapour and food spoilage

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chinese Chemical Letters 2024年第3期35卷 257-261页

作者： Jian-Hao Zhao Wen-Xing Xu Bin Li wei Xu Wu-Kun zhang Ming-Shuai Yuan Hui-Zi Li Qing-Guo He Xiang Ma Jian-{2. Cheng Yan-Yan Fu State Key Lab of Transducer Technology Shanghai Institute of Microsystem and Information TechnologyChinese Academy of SciencesShanghai 200050China Center of Materials Science and Optoelectronics Engineering University of the Chinese Academy of SciencesBeijing 100039China school of Physical Science and Technology ShanghaiTech UniversityShanghai 201210China Key Laboratory for Advanced Materials and Feringa Nobel Prize Scientist Joint Research Center Frontiers Science Center for Materiobiology and Dynamic Chemistry School of Chemistry and Molecular EngineeringEast China University of Science and TechnologyShanghai 200237China

There are urgent needs of volatile amine gas sensors with high-performance in food quality control,disease monitoring and environmental ***-film fluorescent probe is suitable for amine vapour sensing due to its high sensitivity,high selectivity,and no polluting ***,a novel fluorescent probe based on indacenodithiophene structure withπconjugated system was designed and *** experimental results show that the films prepared by this material exhibit rapid and distinct fluorescence quenching after being exposed to saturated vapours of primary amine,secondary amine and tertiary amine represented by n-propylamine,diethylamine and trimethylamine,*** quenching of fluorescence is 84%,87%and 96%,respectively,within 10 *** detection mechanism of probe for primary amine is based on specific chemical reaction,while the detection mechanism for secondary amine and tertiary amine is intramolecular charge *** experiments show that the detection limit of the fluorescent probe for trimethylamine,an important marker of food spoilage,could reach 4.610 ***-site detection based on spoilage of small yellow croaker suggests the material possesses the potential for food freshness *** simple fluorogenic probe is an original approach to simplify real-time visual monitoring of volatile amine vapour.

关键词： Fluorescent probe Volatile amine Gas sensing Trimethylamine Food spoilage

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Development of a MWDC prototype of the CSR external-target experiment

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NUCLEAR SCIENCE AND TECHNIQUES 2024年第10期35卷 1-14页

作者： He, Zhou-Bo Qin, Zhi Ma, Peng Yang, He-Run wei, Xiang-Lun Lu, Chen-Gui Wen, Xiang-Jie zhang, Xiu-Ling Chen, Tao Li, Zhi-Jie Yang, Yuan-Sheng Zhan, Mei-Qiang Liu, Can-Wen Li, Meng Qiu, Tian-Li {2., Yi-wei Huang, Xin-Jie Yin, Xiao-Hao He, Zhi-Xuan zhang, Jun-wei Zou, Hai-Chuan Fu, Sheng-wei Guo, Dong Yan, Jun-wei Cao, Zhe Deng, Zhi Kong, Jie Xiao, Zhi-Gang Hu, Rong-Jiang Duan, Li-Min chinese Acad Sci Inst Modern Phys Lanzhou 730000 Peoples R China Univ chinese Acad Sci Sch Nucl Sci & Technol Beijing 100049 Peoples R China Tsinghua Univ Dept Phys Beijing 100084 Peoples R China Univ Sci & Technol China Hefei 230026 Peoples R China Sichuan Univ Inst Nucl Sci & Technol Key Lab Radiat Phys & Technol Minist Educ Chengdu 610064 Peoples R China Lanzhou Univ Sch Nucl Sci & Technol Lanzhou 730000 Peoples R China North China Univ Water Resources & Elect Power Zhengzhou 450000 Peoples R China

The cooling storage ring (CSR) external-target experiment (CEE) is a spectrometer used in construction to study the properties of nuclear matter in high-baryon density regions at the Heavy-Ion Research Facility in Lanzhou (HIRFL). This study presents the design, simulation, manufacturing, and testing of a half-size prototype of a multi-wire drift chamber (MWDC) for the CEE. First, the performance of the MWDC connected to homemade electronics was simulated. The results demonstrated that an energy resolution of 18.5% % for 5.9-keV X-rays and a position resolution of 194 mu m for protons can be achieved by the current design. Because the size of the largest MWDC reached 176 cm x 3.4 cm, a set of 98 cm x 98 cm prototypes was built using the new techniques. The positioning accuracy of the anode wires in this prototype is better than 2. mu m. After optimization, using commercially available electronics, the prototype can achieved an energy resolution of 19.7% % for a Fe-55 X-ray source. The CEE-MWDC detector and electronics were simultaneously tested. An energy resolution of 2.% % was achieved for the Fe-55 source; the track residuals were approximately 3.0 mu m for the cosmic rays. The results demonstrate that the current design and techniques meet the requirements of the CEE-MWDC array.

关键词： CEE MWDC Garfield plus plus Fe-55 source Position resolution DRIFT CHAMBER HIRFL-CSR

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