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铜代谢异常可影响肺耐药肿瘤细胞对顺铂化疗的反应

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高技术通讯 2005年第11期15卷 74-79页

作者：刘欣荣王子健高锦中国科学院生物物理研究所蛋白质与多肽药物实验室北京100101 中国科学院研究生院北京100039

从细胞水平上研究了人肺腺癌A549细胞获得DDP药物抗性后,调节铜代谢状态对DDP反应的影响.采用DDP抗性为5.25倍的肺腺癌A549/DDP细胞株,观察添加铜和加入铜络合剂TEPA去除铜后A549/DDP对DDP的反应性,结果显示铜代谢变化可影响DDP的作用规... 详细信息

从细胞水平上研究了人肺腺癌A549细胞获得DDP药物抗性后,调节铜代谢状态对DDP反应的影响.采用DDP抗性为5.25倍的肺腺癌A549/DDP细胞株,观察添加铜和加入铜络合剂TEPA去除铜后A549/DDP对DDP的反应性,结果显示铜代谢变化可影响DDP的作用规律.铜与低浓度的DDP具有协同作用,铜和处于有效抑制浓度的DDP联合具有拮抗作用.用TEPA去除铜后,可显著降低DDP的细胞毒作用(P＜0.01).进一步分析表明,铜代谢异常影响A549/DDP对DDP的反应与细胞周期改变和细胞凋亡有关.

关键词：铜 DDP 肿瘤耐药细胞周期凋亡

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聚丙烯酸/丙烯酰胺高吸水性树脂吸附性能

化工学报 2007年第7期58卷 1762-1767页

作者：谢建军梁吉福刘新容刘赛中南林业科技大学材料科学与工程学院流变力学与材料工程研究所湖南长沙410004 湘潭大学高分子材料研究所湖南湘潭411105

Poly(acrylic acid-co-acrylamide)(PAAAM)resin was prepared from acrylic acid(AA)and acrylamide(AM)by inverse suspension *** adsorption of metal ions on PAAAM resin differed greatly at different pH values and initial *** provided a theoretical basis for the application of PAAAM resin to separate transitional metal ions Cu2+,Ni2+,Co2+.The selectivity for competitive adsorption on PAAAM resin in Cu2+,Ni2+ and Co2+ binary and ternary mixed ion solutions were *** was found that there was higher selectivity on PAAAM resin for Cu2+ ions compared with other metal ions used in this study.

关键词：高吸水性树脂离子吸附反相悬浮聚合丙烯酸丙烯酰胺聚丙烯酸/丙烯酰胺

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内陆港口物流竞争力培养刍议——以重庆为例

生态经济 2010年第4期 79-82+119页

作者：刘新荣重庆科技学院

坚持对外开放,着力提高开放型经济水平,对于促进重庆市国民经济又好又快发展具有重要现实意义。港口物流发展是重庆作为内陆开放城市的重要基础和关键环节,把重庆物流成本与物流效率作为突破口显得尤为重要。文章比较分析了当前影响重... 详细信息

坚持对外开放,着力提高开放型经济水平,对于促进重庆市国民经济又好又快发展具有重要现实意义。港口物流发展是重庆作为内陆开放城市的重要基础和关键环节,把重庆物流成本与物流效率作为突破口显得尤为重要。文章比较分析了当前影响重庆水路运输和航空运输外贸物流成本和物流效率的因素,提出相关政策建议,希望对重庆改善外向型经济发展环境,发展港口物流,提高区域经济吸引和辐射能力起到有益参考。

关键词：港口物流成本与效率对策

Serological Prevalence Survey Among the High-Risk Populations of Brucellosis-Endemic Areas-China,2019−2020

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China CDC weekly 2021年第6期3卷 101-105页

作者： Shenghong Lin Zhe Wang xinrong liu Aizhi Yu Muhtar·Hasan Jiensi·Bayidawulieti Haitan·Aximujiang Ruiqing Li Guoxing Zheng Xinwang Liang Xiaoling Fan Biqiao Hou Xiaolong Fan Dilxat·Abuliti Lusha Shi Cuihong Zhang Yifei Wang Pengjing Ning Caixiong liu Zhongjie Li Liping Wang Division of Infectious Disease Key Laboratory of Surveillance and Early Warning on Infectious DiseaseChina Center for Disease Control and PreventionBeijingChina Hangzhou Center for Disease Control and Prevention HangzhouZhejiangChina Datong Center for Disease Control and Prevention DatongShanxiChina Huocheng Center for Disease Control and Prevention YiliXinjiangChina Xinjiang Uygur Autonomous Region Center for Disease Control and Prevention UrumqiXinjiangChina Yili Kazakh Autonomous Prefecture Center for Disease Control and Prevention YiliXinjiangChina Yanggao Center for Disease Control and Prevention DatongShanxiChina Zuoyun Center for Disease Control and Prevention DatongShanxiChina Hunyuan Center for Disease Control and Prevention DatongShanxiChina

What is already known about this topic?Timely screening of high-risk population is important to improve the early detection of brucellosis among the endemic areas during the high incidence seasons,which is also required by the National Brucellosis Prevention and Control Plan(2016–2020)(NBPCP).What is added by this report?Seroepidemiological characteristics of brucellosis in high-risk populations were obtained and special occupational populations were *** seroprevalence of brucellosis has been decreasing compared with that reported in the recent years due to the ongoing implementation of control measures in endemic *** are the implications for public health practice?Special occupational populations could be promptly detected using routine screening,which makes it possible to initiate standardized treatment for infected patients as early as *** also reminds us to pay attention to special occupational populations to improve their knowledge of brucellosis and reduce the risk of infection.

关键词： Population Brucellosis incidence

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集群服务器文件动态分配的改进算法

计算机工程 2007年第6期33卷 56-58,61页

作者：阳光刘欣荣烟台大学光电信息学院烟台264005 山东工商学院电子工程系烟台264005

在分析MMPacking算法的基础上,提出了一种改进的文件分配算法。在按照MMPacking算法分配文件时,根据节点的文件累积需求度去完成文件的分配或复制,考虑了节点的剩余能力。文件分配在所有服务器节点中周期性地进行,每进行了一轮文件分配... 详细信息

在分析MMPacking算法的基础上,提出了一种改进的文件分配算法。在按照MMPacking算法分配文件时,根据节点的文件累积需求度去完成文件的分配或复制,考虑了节点的剩余能力。文件分配在所有服务器节点中周期性地进行,每进行了一轮文件分配后,都要从第1个节点开始新的一轮分配。在开始新一轮分配前,服务器节点要按照服务器的剩余能力重新进行降序排列。在每轮分配中,每分配一次文件到某个服务器节点后,都要检测当前节点服务器的剩余能力是否大于下一节点的剩余能力,如果满足条件,则将重新开始新的一轮文件分配。改进后的算法降低了由于客户需求或服务器配置变化所要支出的额外成本,有效地达到了负载均衡的目的。仿真结果表明,改进后的算法优于MMPacking算法。

关键词：集群服务器文件动态分配算法

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既有线路基提速改造健康状态综合评价方法

西南交通大学学报 2012年第4期47卷 591-596页

作者：方焘刘新荣耿大新刁心宏重庆大学土木工程学院重庆400045 华东交通大学土木建筑学院江西南昌330013 重庆大学山地城镇建设与新技术教育部重点实验室重庆400045

为了对既有线路提速改造,需要对其路基健康状态进行评价.在现场调查路基健康状态的基础上,按路基病害轻重程度、填料类型与基床结构的不同,将路基区划分为24个检测段,共开展754组密实度、345组动弹性模量和1 311个不同部位轻型动力触探... 详细信息

为了对既有线路提速改造,需要对其路基健康状态进行评价.在现场调查路基健康状态的基础上,按路基病害轻重程度、填料类型与基床结构的不同,将路基区划分为24个检测段,共开展754组密实度、345组动弹性模量和1 311个不同部位轻型动力触探试验,并进行综合分析.分析结果表明:以现场调查为基础,采用轻型动力触探、密实度、动弹性模量相结合的既有线路基健康状态综合评价方法,能全面反映路基强度、刚度、耐久性的状态,是既有线路基健康状态评价的可靠方法之一,试验结果可直接应用于路基工程改造技术方案的设计.

关键词：路基提速改造健康状态综合评价

Characteristics of soil water repellency after sand dune stabilization in the Tengger Desert

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Research in Cold and Arid Regions 2012年第5期4卷 408-416页

作者： HaoTian Yang LiChao liu xinrong Li YongPing Wei YanHong Gao XiaoJun Li RongLiang Jia Lei Huang Shapotou Desert Research and Experiment Station Cold and Arid Regions Environmental and Engineering Research Institute Chinese Academy of Sciences Lanzhou Gansu 730000 China

Soil water repellency （SWR） is one of the most important physical properties of soils found all over the world, and it may have significant effects on the eco-hydrological processes of land ecosystems. In this study, the Capillary Rise Method was used to measure the SWR in the artificial vegetation area in Shapotou, located in the southeast area of the Tengger Desert, Ningxia Prov- ince of western China. The variation of the soil water repellency among different minor topographies, different depths and differ- ent particle sizes was analyzed. The results of the study indicate that the SWR shows distinct changes with vegetation restoration, and it increases with an increase in the period of dune stabilization. In the same vegetation area, the SWR of soils in inter-dune depressions or windward slopes is slightly greater than that in crest or leeward slopes. The SWR of 0-3 cm topsoil is significantly greater than that in the 3-6 cm soil layer. The SWR decreases with an increase in grain size and the differences among the SWRs of different sieved soil fractions are found to be significant. There is also a significantly positive correlation between the SWR and the proportion of soils with grain sizes of 0-0.05, 0.05-0.01 and 0.01-0.15 mm, and a significantly negative correlation between the SWR and the propotion of soils with grain sizes exceeding 0.15 mm. The increase of SWR in revegetation areas may depend on the continuous depositing of atmospheric dust on the stabilized dune surface as well as the formation of biological soil crusts, especially on the formation of algal and lichen crusts. Enhanced SWR influences the effectiveness of water use of sand plants in- habiting the sand dunes.

关键词： soil water repellency soil contact angle Capillary Rise Method vegetation restoration southeast area of the Tengger Desert

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高校校园地下空间开发利用策略及案例分析

地下空间与工程学报 2024年第5期20卷 1432-1441页

作者：刘瀚之刘新荣周小涵王䶮重庆大学土木工程学院重庆400045 库区环境地质灾害防治国家地方联合工程研究中心重庆400045 山地城镇建设与新技术教育部重点实验室(重庆大学) 重庆400045

高等教育的快速发展导致高校可开发用地日益紧张,师生住宿、生活空间资源短缺,地下空间的开发利用逐渐成为高校建设的重中之重。本文通过阐明高校地下空间发展动因,整理地下空间类型及开发模式,梳理国内外高校地下空间特点,并以西南地... 详细信息

高等教育的快速发展导致高校可开发用地日益紧张,师生住宿、生活空间资源短缺,地下空间的开发利用逐渐成为高校建设的重中之重。本文通过阐明高校地下空间发展动因,整理地下空间类型及开发模式,梳理国内外高校地下空间特点,并以西南地区某高校为例具体分析,进而预测高校校园地下空间开发趋势。研究表明:高校地下空间开发需要注重时代延续、强调景观协同,在进行具体设计时强化单体地下空间职能、提高空间纵深,打造具有“学习生活交往”复合职能的地下综合体,设计时加强多点联通,兼顾整体协同,将高校校园地下空间作为一个建设整体进行规划设计,同时注重地下空间开发中的动静交通结合,打造智能化的地下空间,才能构建集约化、高质量的高校校园地下空间。

关键词：校园规划地下空间开发利用案例分析

Brucellosis Knowledge and Personal Protective Equipment Usage Among High-Risk Populations in Brucellosis-Endemic Areas-China,2019−2020

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China CDC weekly 2021年第6期3卷 106-109页

作者： Zhe Wang Shenghong Lin xinrong liu Aizhi Yu Muhtar·Hasan Jiensi·Bayidawulieti Haitan·Aximujiang Ruiqing Li Guoxing Zheng Xinwang Liang Xiaoling Fan Biqiao Hou Xiaolong Fan Dilxat·Abuliti Lusha Shi Cuihong Zhang Yifei Wang Pengjing Ning Caixiong liu Zhongjie Li Liping Wang Hangzhou Center for Disease Control and Prevention HangzhouZhejiangChina Division of Infectious Disease Key Laboratory of Surveillance and Early Warning on Infectious DiseaseChinese Center for Disease Control and PreventionBeijing China Datong Center for Disease Control and Prevention DatongShanxiChina Huocheng Center for Disease Control and Prevention YiliXinjiangChina Xinjiang Uygur Autonomous Region Center for Disease Control and Prevention UrumqiXinjiang Uygur Autonomous RegionChina Yili Kazakh Autonomous Prefecture Center for Disease Control and Prevention YiliXinjiangChina Yanggao Center for Disease Control and Prevention DatongShanxiChina Zuoyun Center for Disease Control and Prevention DatongShanxiChina Hunyuan Center for Disease Control and Prevention DatongShanxiChina

What is already known about this topic?According to the National Brucellosis Prevention and Control Plan(2016–2020)(NBPCP),the awareness rate of high-risk populations in brucellosis-endemic areas should reach 90%by *** the updated results have not been *** is added by this report?This report determined the awareness rate of brucellosis(17.74%),utilization of personal protective equipment(PPE)(20.13%),and their relationship with seroprevalence,which provides evidence for the effectiveness of the implementation of *** are the implications for public health practice?The results suggest that health education should be conducted for high-risk populations to improve their brucellosis and protection knowledge.

关键词： Population Brucellosis