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Hyperthermic intraperitoneal chemotherapy for gastric and colorectal cancer in China's Mainland

World Journal of Gastroenterology 2011年第8期17卷 1071-1075页

作者： Tao Suo Haile Mahteme xin-yu qin Department of General Surgery Zhong-shan Hospital Fudan University General Surgery Institute ofFudan University Shanghai 200032 China Department of Surgical Sciences UppsalaUniversity SE75185 Uppsala Sweden

AIM:To investigate the current status of peritoneal carcinomatosis(PC) management,as well as the usage of cytoreductive surgery(CRS) and hyperthermic intraperitoneal chemotherapy(HIPEC) in China's ***:A potentially curative therapeutic strategy for selecting patients with PC,known as "Techniques",consists of CRS in combination with HIPEC.A systemic search of published works and clinical trials was *** papers were retrieved by crosschecking references and obtaining information from Chinese oncologists and relevant *** hundred and one papers and one registered clinical trial on HIPEC were ***:A literature review identified 86 hospitals in 25 out of all 31 areas of China's Mainland that perform *** earliest report included in our survey was published in *** approaches to HIPEC have been utilized,***,prophylactic,and possiblycurative *** one center has consistently performed HIPEC according to the "Sugarbaker Protocol",which involves evaluating the extent of PC with peritoneal cancer index and the results of CRS with the completeness of *** preliminary results were reported:7 of 21 patients with PC survived,free of tumors,during an 8-43-mo follow-up *** strategies that include HIPEC have been practiced for a long time in China's Mainland,whereas the "Sugarbaker Protocol/Techniques" has been only rarely implemented in *** Peritoneal Surface Oncology Group International hosts a biannual workshop with the intent to train more specialists in this field and provide support for the construction of quality treatment centers,especially in developing countries like China,whose population is huge and has a dramatically increased incidence of ***:To popularize Sugarbaker Protocol/Techniques in China's Mainland in PC management arising from gastric cancer or colorectal cancer will be the responsibility of the upcoming Chinese Peritonea

关键词： Peritoneal carcinomatosis Hyperthermia Prophylactic strategy Sugarbaker Protocol/techniques China's Mainland

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Contrasting changes in above- and below-ground biomass allocation across treeline ecotones in southeast Tibet

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Journal of Mountain Science 2016年第11期13卷 2036-2045页

作者： Liu xin-sheng Nie yu-qin Kong Gao-qiang Luo Tian-xiang College of Tourism and Territorial Resources Jiujiang University Jiujiang 332005 China Key Laboratory of Alpine Ecology and Biodiversity Institute of Tibetan Plateau Research Chinese Academy of Sciences Beijing 100101 China School ofAccountancy Jiujiang University Jiujiang 332005 China

Under conditions of a warmer climate,the advance of the alpine treeline into alpine tundra has implications for carbon dynamics in mountain ***,the above- and below-ground live biomass allocations among different vegetation types within the treeline ecotones are not well *** determine the altitudinal patterns of above-/below-ground carbon allocation,we measured the root biomass and estimated the above-ground biomass(AGB) in a subalpine forest,treeline forest,alpine shrub,and alpine grassland along two elevational transects towards the alpine tundra in southeast *** AGB strongly declined with increasing elevation,which was associated with a decrease in the leaf area index and a consequent reduction in carbon *** fine root biomass(FRB) increased significantly more in the alpine shrub and grassland than in the treeline forest,whereas the coarse root biomass changed little with increasing altitudes,which led to a stable below-ground biomass(BGB) value across *** and infertile soil conditions might explain the large amount of FRB in alpine shrub and ***,the root toshoot biomass ratio increased sharply with altitude,which suggested a remarkable shift of biomass allocation to root systems near the alpine *** findings demonstrate contrasting changes in AGB and BGB allocations across treeline ecotones,which should be considered when estimating carbon dynamics with shifting treelines.

关键词： Treeline ecotone Fine root biomass Above-ground biomass Vegetation type Southeast Tibet

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Finite element analysis for die casting parameters in high-pressure die casting process

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China Foundry 2019年第4期16卷 272-276页

作者： xin-yu qin Yong Su Jian Chen Lan-jun Liu School of Materials Science and Engineering Hefei University of Technology

The gating system and the overflow system were designed according to the casting structure during high pressure die casting(HPDC) process. The simulation was carried out by ProCAST software to visualize the injection chamber pre-crystallization and the flow of molten metal. The main work is to research four die casting process parameters, i.e. injection temperature, low-pressure velocity, high-and low-pressure velocity’s switching position, and high-pressure velocity. Experimental results show that the higher injection temperature and lowpressure velocity can mitigate the pre-crystallization of the injection chamber. However, when the low-pressure velocity exceeds 0.2 m·s-1, the air entrapment in the chamber occurs. Besides, when the high-pressure velocity is greater than 2.5 m·s-1, the overflow channel at the final filling position is covered by the liquid metal too early. Finally, the injection temperature of 650 °C, the low-pressure velocity of 0.2 m·s-1, the high-and low-pressure velocity’s switching position of 320 mm and the high-pressure velocity of 2 m·s-1 are obtained as the optimal parameters by the software simulation, which has been verified by actual production.

关键词： aluminum alloy die casting process simulation optimization

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Clinicopathological analysis of patients with gastric cancer in 1200 cases

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World Journal of Gastroenterology 2001年第2期7卷 281-284页

作者： Wei xin Niu xin yu qin Han Liu Cheng Pei Wang Surgical Department, Zhongshan Hospital, Fu Dan University Medical Center, Shanghai 200032, China Surgical Department Zhongshan Hospital Fu Dan University Medical Center136 Yixueyuan Road Shanghai 200032China.

INTRODUCTIONGastric cancer is one of the most common fatal malignancies in the world. The prognosis is generally poor in advanced gastric cancer .The low survival is related to delayed diagnosis, metastasis and recurrence after operation .The aim of this paper was to find correlation between clinical factors was to find correlation between clinical factors and biologic behavior of gastric cancer in a series of 1200 patients undergoing surgical resection.

关键词： Adult Aged Aged, 80 and over Female Gastrectomy Humans Lymphatic Metastasis Male Middle Aged Retrospective Studies Stomach Neoplasms

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High-Performanceα-Diimine Nickel Complexes for Facile Access of PE Elastomers with Exceptional Material Properties

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Chinese Journal of Polymer Science 2024年第5期42卷 620-635,I0008页

作者： Li-Dong qin xin-yu Wang Qaiser Mahmood Zhi-xin yu Yi-Zhou Wang Song Zou Tong-Ling Liang Wen-Hua Sun School of Pharmaceutical Sciences Changchun University of Chinese MedicineChangchun130117China Chemistry and Chemical Engineering Guangdong Laboratory Shantou515031China Key Laboratory of Engineering Plastics and Beijing National Laboratory for Molecular Science Institute of ChemistryChinese Academy of SciencesBeijing100190China

For practicable elastomeric polyethylene,achieving high catalyst thermal stability and activity,along with precise control of polymer properties such as branching density,molecular weights,and distribution,is crucial but *** this study,two sets of symmetricalα-diimine nickel complexes,each comprising four nickel bromide or chloride complexes,were synthesized and investigated their performance for ethylene polymerization under various reaction *** activation with either Et2AlCl or MMAO cocatalysts,these complexes displayed not only high activity but also generated high molecular weight polyethylenes with controlled polydispersity and a substantial number of *** catalyst with the least steric hindrance displayed the remarkable high activity(up to 1.2×10^(7) g·mol^(-1)·h^(-1)).Notably,nickel bromides demonstrated higher activity compared to their chloride *** investigation into the effect of reaction temperature on catalytic performance revealed that NiBrMe-MMAO system displayed high thermal stability(activity up to 2.51×10^(6) g·mol^(-1)·h^(-1) at 100℃)and consistently yielded high polymer molecular weights with narrow polydispersity over a broad temperature range of 30-100℃.Of significant note,mechanical analysis of the resulting polyethylene demonstrated excellent ultimate tensile strength and high strain at ***,the polyethylene sample prepared at 100℃exhibited ultimate tensile strength up to 10 MPa with 1863%maximum strain at break and a strain recovery of up to 54.9%after ten cycles at a fixed strain of 300%,indicating excellent material properties of prepared thermoplastic polyethylene elastomers(TPE).

关键词： Thermoplastic polyethylene elastomers α-Diimine nickel pre-catalysts Ethylene polymerization Mechanical properties Highly branched polyethylene

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Stress corrosion cracking behavior of buried oil and gas pipeline steel under the coexistence of magnetic field and sulfate-reducing bacteria

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Petroleum Science 2024年第2期21卷 1320-1332页

作者： Jian-yu He Fei Xie Dan Wang Guang-xin Liu Ming Wu yue qin College of Petroleum Engineering Liaoning Petrochemical UniversityFushun113001LiaoningChina Key Laboratory of Oil and Gas Storage and Transportation Technology in Liaoning Province Fushun113001LiaoningChina State Key Joint Laboratory of Environment Simulation and Pollution Control School of EnvironmentTsinghua UniversityBeijing100084China PipeChina West East Gas Pipeline Company Shanghai200120China

Magnetic field and microorganisms are important factors influencing the stress corrosion cracking(SCC)of buried oil and gas pipelines. Once SCC occurs in buried pipelines, it will cause serious hazards to the soil environment. The SCC behavior of X80 pipeline steel under the magnetic field and sulfate-reducing bacteria(SRB) environment was investigated by immersion tests, electrochemical tests, and slow strain rate tensile(SSRT) tests. The results showed that the corrosion and SCC sensitivity of X80 steel decreased with increasing the magnetic field strength in the sterile environment. The SCC sensitivity was higher in the biotic environment inoculated with SRB, but it also decreased with increasing magnetic field strength, which was due to the magnetic field reduces microbial activity and promotes the formation of dense film layer. This work provided theoretical guidance on the prevention of SCC in pipeline steel under magnetic field and SRB coexistence.

关键词： Magnetic field Sulfate-reducing bacteria Film layer Stress corrosion cracking Oil and gas pipelines

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Intra-abdominal inflammatory myofibroblastic tumor:Spontaneous regression

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World Journal of Gastroenterology 2014年第37期20卷 13625-13631页

作者： Jun-Jie Zhao Jia-Qian Ling Yong Fang Xiao-Dong Gao Ping Shu Kun-Tang Shen Jing qin Yi-Hong Sun xin-yu qin Department of General Surgery Zhong Shan HospitalFudan University

Inflammatory myofibroblastic tumors are usually treated by surgical resection. We herein report two cases of intra-abdominal inflammatory myofibroblastic tumors that were unresectable and underwent spontaneous regression without any treatment. Our case report and literature review show that regression is more common in the middle-aged and older male populations. Abdominal discomfort and fever were the most common symptoms, but the majority of patients had no obvious physical signs. There was no specific indicator for diagnosis. The majority of the lesions regressed within3 mo and nearly all of the masses completely resolved within 1 year. We conclude that the clinical characteristics of inflammatory myofibroblastic tumors are variable and, accordingly, the disease needs to be subdivided and treated on an individual basis. Surgery is always the first-line treatment; however, for those masses assessed as unresectable, conservative therapy with in-tense follow-up should be considered.

关键词： Inflammatory myofibroblastic tumor Inflammatory pseudotumor Abdominal cavity Spontaneous regression

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Assessment of T staging and mesorectal fascia status using high-resolution MRI in rectal cancer with rectal distention

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World Journal of Gastroenterology 2007年第30期13卷 4141-4146页

作者： Sheng-Xiang Rao Meng-Su Zeng Jian-Ming Xu xin-yu qin Cai-Zhong Chen Ren-Chen Li Ying-Yong Hou Department of Radiology Zhongshan Hospital Fudan University and Shanghai Medical Imaging Institute Shanghai 200032 China Department of General Surgery Zhongshan Hospital Fudan University Shanghai 200032 China Department of Pathology Zhongshan Hospital Fudan University Shanghai 200032 China

AIM： To determine the accuracy of high-resolution magnetic resonance imaging （MRI） using phasedarray coil for preoperative assessment of T staging and mesorectal fascia infiltration in rectal cancer with rectal distention.METHODS： In a prospective study of 67 patients with primary rectal cancer, high-resolution magnetic resonance imaging （in-plane resolution, 0.66 × 0.56） with phased-array coil were performed for T-staging and measurement of distance between the tumor and the mesorectal fascia. The assessment of MRI was compared with postoperative histopathologic findings. Sensitivity, specificity, accuracy, positive predictive value, and negative predictive value were evaluated.RESULTS： The overall magnetic resonance accuracy was 85.1% for Tstaging and 88% for predicting mesorectal fascia involvement. Magnetic resonance sensitivity, specificity, accuracy, positive predictive value, and negative predictive value was 70%, 97.9%, 89.6%, 93.3% and 88.5% for ≤ T2 tumors, 90.5% , 76% , 85.1%, 86.4% and 82.6% for T3 tumors, 100%, 95.2%, 95.5% , 62.5% and 100% for T4 tumors, and 80% , 90.4%, 88%, 70.6% and 9d% for predicting mesorectal fascia involvement, respectively.CONCLUSION： High-resolution MRI enables accurate preoperative assessment for T staging and mesorectal fascia infiltration in rectal cancer with rectal distention.

关键词： Magnetic resonance imaging Rectum Neoplasm Staging Mesorectal fascia

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Acute acalculous cholecystitis immediately after gastric operation:Case report and literatures review

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World Journal of Gastroenterology 2014年第30期20卷 10642-10650页

作者： Feng-Lin Liu He Li Xue-Fei Wang Kun-Tang Shen Zhen-Bin Shen Yi-Hong Sun xin-yu qin Department of General Surgery Zhongshan HospitalFudan University

Acute acalculous cholecystitis(AAC)is a rare complication of gastric *** most commonly accepted concepts regarding its pathogenesis are bile stasis,sepsis and ischemia,but it has not been well described how to identify and manage this disease in the early *** report three cases of AAC in elderly patients immediately after gastric surgery,which were treated with three different *** patient died 42 d after emergency cholecystectomy,and the other two finally recovered through timely cholecystostomy and percutaneous transhepatic gallbladder drainage,*** cases informed us of the value of early diagnosis and proper treatment for perioperative AAC after gastric *** further reviewed reported cases of AAC immediately after gastric operation,which may expand our knowledge of this disease.

关键词： Acute acalculous cholecystitis Postoperative complication Gastric surgery

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Chiral Lewis Base/Achiral Acid Co-Catalyzed Atroposelective Sulfenylation of Pyrrole Derivatives: Construction of C-N Axially Chiral Sulfides

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Chinese Journal of Chemistry 2024年第17期42卷 2005-2009页

作者： qin Yang Hui-yun Luo Deng Zhu xin-yu Zhang Hua Ke Zhi-Min Chen School of Chemistry and Chemical Engineering Shanghai Key Laboratory for Molecular Engineering of Chiral DrugsShanghai Jiao Tong UniversityShanghai 200240China Engineering Technooy Rearch Centeror Enviromental Proction Materas Pingxng Universty PingangJiangx355China State Key Laboratory of Applied Organic Chemistry Lanzhou UniversityLanzhouGansu 730000China

Chiral BINAM-derived selenide/achiral acid co-catalyzed atroposelective electrophilic sulfenylation of pyrrole derivatives has been realized for the first time.A variety of C-N axially chiral sulfur-containing pyrrole derivatives were readily obtained in moderate to good yields with moderate to excellent *** catalytic system involves sequential desymmetrization and kinetic resolution.

关键词： Electrophilic substitution Desymmetrization Kinetic resolution Atropisomerism Asymmetric catalysis Heterocycles

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