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Dihydromyricetin ameliorates chronic liver injury by reducing pyroptosis

World Journal of Gastroenterology 2020年第41期26卷 6346-6360页

作者： Quan-Cheng Cheng Jing Fan xin-wei deng Huai-Cun Liu Hui-Ru Ding Xuan Fang Jian-wei Wang Chun-Hua Chen wei-Guang Zhang Department of Anatomy Histology and EmbryologySchool of Basic Medical SciencesPeking University Health Science CenterBeijing 100191China xin Hua Hospital Shanghai Jiaotong University School of MedicineShanghai 202155China

BACKGROUND Chronic liver injury(CLI) is now a worldwide disease. However, there is no effective treatment. Pyroptosis plays an essential role in CLI. Dihydromyricetin(DHM) resists oxidation and protects the liver. We hypothesize that the beneficial effect of DHM on CLI is related to its effect on the expression of pyroptosisrelated molecules. Therefore, we studied the influence of DHM on CLI and *** To study the role of pyroptosis in the pathogenesis of CLI and the therapeutic mechanism of *** Thirty-two mice were randomly divided into four groups: The control group was injected with olive oil, the carbon tetrachloride(CCl4) group was injected with CCl4, the vehicle group was injected with hydroxypropyl-β-cyclodextrin while injecting CCl4 and the DHM group was injected with DHM while injecting CCl4. After four weeks of treatment, liver tissues from the mice were stained with hematoxylin and eosin, and oil red O. Blood was collected from the angular vein for serological analysis. The severity of CLI was estimated. Some liver tissue was sampled for immunohistochemistry, Western blotting and quantitative reverse transcription PCR to observe the changes in pyroptosis-related *** Serum total cholesterol, low density lipoprotein, aspartate aminotransferase(AST) and alanine aminotransferase(ALT) in the CCl4 group were higher than those in the control group, and serum total cholesterol, low density lipoprotein, AST and ALT in the DHM group were lower than those in the vehicle group. Hematoxylin and eosin and oil red O staining showed that there were more lipid droplets in the CCl4 group than in the control group, and there were fewer lipid droplets in the DHM group than in the vehicle group. Western blotting showed that the expression of the pyroptosis-related molecules caspase-1, NOD-, LRR-and pyrin domain-containing 3(NLRP3) and gasdermin D(GSDMD)-N in the CCl4 group was higher than that in the control group, while expression of these prot

关键词： Chronic liver injury Dihydromyricetin Pyroptosis Carbon tetrachloride Pathogenesis Steatosis

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Experimental investigation on flame stabilization of a kerosene-fueled scramjet combustor with pilot hydrogen

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2020年第8期21卷 663-672页

作者： Wen SHI Ye TIAN Wan-zhou ZHANG wei-xin deng Fu-yu ZHONG Jia-ling LE China Aerodynamic Research and Development Center Mianyang 621000China

Flame stabilization in a kerosene-fueled scramjet combustor was investigated experimentally through Schlieren,flame luminosity,and wall pressure measurement,aiming to obtain better insight into combustion *** were conducted in a direct-connected supersonic combustion facility with inflow conditions of Mach number 2.0,stagnation pressure 0.82 MPa,and temperature 950 K,simulating the flight condition of Mach number *** revealed that kerosene was able to be ignited when the equivalence ratio of pilot hydrogen reached 0.080,but was unsuccessful when the equivalence ratio was *** ignited,the intense combustion induced high back pressure forcing the flame to spread into the *** pilot flame invariably appeared in the cavity shear layer and attached to the cavity ramp under different equivalence ratios of pilot *** the mass flux of pilot hydrogen increased,the kerosene flame located near the cavity ramp was asymmetrical and unstable since it propagated upstream ***,the kerosene could be ignited by a suitable equivalence ratio of continuous pilot hydrogen,potentially accompanied with unstable combustion.

关键词： Scramjet Flame stabilization Pilot hydrogen Kerosene Supersonic combustion

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How can photoreceptor cells breathe in the retina? Neuroglobin may be the answer

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Neural Regeneration Research 2010年第9期5卷 720-720页

作者： xin wei Yingping deng Xuyang Liu Lin Wang Xiaoming Chen Department of Ophthalmology & Ophthalmic Laboratories West China HospitaI Sichuan University Chengdu 610041 Sichuan ProvinceChina

Dear Editor, The retina is one of the highest oxygen-consuming tissues in the body because the visual process in the vertebrate eye needs a large amount of metabolic energy[1-2].

关键词： photoreceptor retina Neuroglobin

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Recent progress in constructing fluorinated solid-electrolyte interphases for stable lithium metal anodes

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 270-291页

作者： Di Zhang Pengfei Lv wei Qin xin He Yuanhua He Civil Aircraft Fire Science and Safety Engineering Key Laboratory of Sichuan Province College of Civil Aviation Safety EngineeringCivil Aviation Flight University of ChinaGuanghan 618307China School of Chemical Engineering Sichuan UniversityChengdu 610065China

Lithium metal batteries(LMBs)are emerging as a promising energy storage solution owing to their high energy density and specific ***,the non-uniform plating of lithium and the potential rupture of the solid-electrolyte interphase(SEI)during extended cycling use may result in dendrite growth,which can penetrate the separator and pose significant short-circuit *** a stable SEI is essential for the long-term operation of the ***-rich SEI has garnered significant attention for its ability to effectively passivate electrodes,regulate lithium deposition,and inhibit electrolyte *** the structural components and preparation methods of existing fluorinated SEI is crucial for optimizing lithium metal anode *** paper reviews the research on optimizing LiF passivation interfaces to protect lithium metal *** focuses on four types of compositions in fluorinated SEI that work synergistically to enhance SEI *** instance,combining compounds with LiF can further enhance the mechanical strength and ionic conductivity of the *** metals with LiF significantly improves electrochemical performance at the SEI/anode interface,with a necessary focus on reducing electron tunneling ***,incorporating polymers with LiF offers balanced improvements in interfacial toughness and ionic conductivity,though maintaining structural stability over long cycles remains a critical area for future *** alloys combined with LiF increase surface energy and lithium affinity,challenges such as dendrite growth and volume expansion *** summary,this paper emphasizes the crucial role of interfacial structures in LMBs and offers comprehensive guidance for future design and development efforts in battery technology.

关键词： LiF lithium metal anodes solid-electrolyte interphase interface cycling stability

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HF Radar Target identification Based on Optimized Multi-frequency Features

HF Radar Target identification Based on Optimized Multi-freq...

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2006 CIE International Conference on Radar

作者： Guang-xin Wu wei-bo deng Research Institute of Electronic Engineering Harbin Institute of Technology

In this paper,multi-frequency target radar cross section （RCS） of high frequency surface wave radar （HFSWR） is used for airplane target *** working frequency optimization selection is investigated for an optimization selection method based on the Minimum Classification Error （MCE） rule in order to improve airplane target identification performance;Target RCS is compensated with the consideration of the influence of ground wave propagation attenuation and ocean wave additional *** using this method,identification results of ten types of airplane targets are given with different working frequency numbers in different signal to noise ratio （SNR）.Simulations indicate that identification performance of frequency optimization is improved remarkably compared with the performance of random frequency selection,and the reliable airplane target identification using this method can be realized at lower SNR with fewer working frequency numbers.

关键词： High frequency Radar identification frequency select multiple frequency

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From waste to wealth:Coal tar residue derived carbon materials as low-cost anodes for potassium-ion batteries

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 464-475页

作者： Zhonghua Lu Jun Shen xin Zhang Lingcong Chao Liang Chen Ding Zhang Tao wei Shoudong Xu College of Chemical Engineering and Technology Taiyuan University of TechnologyTaiyuan 030024China College of Chemistry Taiyuan University of TechnologyTaiyuan 030024China School of Chemical Engineering and Pharmacy Wuhan Institute of TechnologyWuhan 430205China School of Energy and Power Jiangsu University of Science and TechnologyZhenjiang 212003China

Carbon materials are widely recognized as highly promising electrode materials for various energy storage system *** tar residues(CTR),as a type of carbon-rich solid waste with high value-added utilization,are crucially important for the development of a more sustainable *** this study,we employed a straightforward direct carbonization method within the temperature range of 700-1000℃to convert the worthless solid waste CTR into economically valuable carbon materials as anodes for potassium-ion batteries(PIBs).The effect of carbonization temperature on the microstructure and the potassium ions storage properties of CTR-derived carbons(CTRCs)were systematically explored by structural and morphological characterization,alongside electrochemical performances *** on the co-regulation between the turbine layers,crystal structure,pore structure,functional groups,and electrical conductivity of CTR-derived carbon carbonized at 900℃(CTRC-900H),the electrode material with high reversible capacity of 265.6m Ah·g^(-1)at 50 m A·g^(-1),a desirable cycling stability with 93.8%capacity retention even after 100 cycles,and the remarkable rate performance for PIBs were ***,cyclic voltammetry(CV)at different scan rates and galvanostatic intermittent titration technique(GITT)have been employed to explore the potassium ions storage mechanism and electrochemical kinetics of *** indicate that the electrode behavior is predominantly governed by surface-induced capacitive processes,particularly under high current densities,with the potassium storage mechanism characterized by an“adsorption-weak intercalation”*** work highlights the potential of CTR-based carbon as a promising electrode material category suitable for high-performance PIBs electrodes,while also provides valuable insights into the new avenues for the high value-added utilization of CTR.

关键词： coal tar residue carbon materials anode potassium-ion batteries high value-added

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A novel active-passive protection strategy endows carbonyl iron with excellent intelligent anti-corrosion and microwave absorption dual functional characteristics

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Nano Research 2025年第1期18卷 487-500页

作者： wei Tian Quanyuan Feng Linbo Zhang Yinfan Liu Xian Jian Longjiang deng Institute of Microelectronics School of Information Science and TechnologySouthwest Jiaotong UniversityChengdu 611756China National Engineering Researching Centre of Electromagnetic Radiation Control Materials Key Laboratory of Multi-Spectral Absorbing Materials and Structures of Ministry of EducationState Key Laboratory of Electronic Thin Films and Integrated DevicesSchool of Electronic Science and EngineeringUniversity of Electronic Science and Technology of ChinaChengdu 611731China School of Materials and Energy University of Electronic Science and Technology of ChinaChengdu 611731China The Yangtze Delta Region Institute(Huzhou)&School of Electronic Science and Engineering University of Electronic Science and Technology of ChinaHuzhou 313001China

Carbonyl iron absorbers(CI)face significant challenges in practical applications,such as corrosion,interface bonding failure,detachment,and high maintenance ***,we have developed intelligent self-healing technology based on proactive/passive mechanisms via in situ synthesis of self-healing factors(polydopamine/benzotriazole(PDA/BTA))and physical barrier layers(SiO_(2)/1,1,1,3,3,3-hexamethyl disilazane,SiO_(2)/HMDS)to enhance corrosion resistance,while also being compatible with efficient microwave absorption *** unique multiscale structure gives full play to the utilization of the roles of each functional layer,including the intelligent self-healing features of PDA/BTA,physical shielding and spatial confinement characteristics of SiO_(2)/HMDS,and magnetic-dielectric synergistic mechanism resulted from the good impedance matching characteristics,the conduction loss,the interfacial polarization loss and natural *** asfabricated composites achieved an exceptional minimum reflection loss value of-55.4 dB at 10.7 GHz and the effective absorption band of 7.6 ***,it still exhibits obvious self-healing and corrosion resistance characteristics after 360 h corrosion treatment,ascribed to the self-healing mechanism of PDA/BTA and the blocking intervention effect of SiO_(2)/*** work is considered to pave the way for the synthesis of high-performance magnetic absorbers,especially in enhancing their intelligent self-healing ability in corrosive environments.

关键词： microwave absorption intelligent self-healing technology carbonyl iron multiscale structure magneticdielectric synergistic mechanism

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最优区域划分的飞行器视觉测量标记

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探测与控制学报 2017年第2期39卷 115-119,123页

作者：姜威辛海华邓永福厉智强北京宇航系统工程研究所北京100076

针对现有标记无法适应回转体飞行器曲面结构的问题,提出了最优区域划分的飞行器视觉测量标记设计方法。该方法首先根据飞行器截面成像模型将飞行器划分为6个子区域,保证飞行器成像中始终有一个完整的子区域;然后将子区域作为标记基本单... 详细信息

针对现有标记无法适应回转体飞行器曲面结构的问题,提出了最优区域划分的飞行器视觉测量标记设计方法。该方法首先根据飞行器截面成像模型将飞行器划分为6个子区域,保证飞行器成像中始终有一个完整的子区域;然后将子区域作为标记基本单元并将区域顶点作为标记点,在标记点满足共面约束的同时使点间的距离最大;最后根据颜色分布特性为子区域设计标识码,实现子区域之间的区分。仿真实验结果表明,当飞行器处于摄像机视场内时,标记成像中始终有一个完整的子区域,在子区域上能提取4个共面特征点用于飞行器位姿参数的准确解算。设计的曲面标记能够满足回转体飞行器(如炮弹弹丸、导弹等)视觉测量的要求。

关键词：兵器科学与技术飞行器位姿测量视觉测量标记

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A low redox potential and long life organic anode material for sodium-ion batteries

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Journal of Energy Chemistry 2025年第1期100卷 557-564页

作者： Zhi Li Yang wei Kang Zhou xin Huang xing Zhou Jie Xu Taoyi Kong Junwei Lucas Bao Xiaoli Dong Yonggang Wang Department of Chemistry and Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials Institute of New Energy Collaborative Innovation Center of Chemistry for Energy Materials (iChEM) Fudan University Department of Chemistry Boston College School of Materials Science and Engineering Anhui University of Technology

Sodium-ion batteries （SIBs） with organic electrodes are an emerging research direction due to the sustainability of organic materials based on elements like C,H,O,and sodium ***,organic electrode materials for SIBs are mainly used as cathodes because of their relatively high redox potentials（>1 V）.Organic electrodes with low redox potential that can be used as anode are ***,a novel organic anode material （tetrasodium 1,4,5,8-naphthalenetetracarboxylate,Na4TDC） has been developed with low redox potential （<0.7 V） and excellent cyclic *** three-sodium storage mechanism was demonstrated with various in-situ/ex-situ spectroscopy and theoretical calculations,showing a high capacity of 208 mAh/g and an average decay rate of merely 0.022%per ***,the Na4TDC-hard carbon composite can further acquire improved capacity and cycling stability for 1200 cycles even with a high mass loading of up to 20 mg *** pairing with a thick Na3V2（PO4）3cathode (20.6 mg cm-2),the as-fabricated full cell exhibited high operating voltage （2.8 V）,excellent rate performance and cycling stability with a high capacity retention of 88.7% after 200 cycles,well highlighting the Na4TDC anode material for SIBs.

关键词： Organic anode material Low redox potential Composite anode Sodium-ion batteries

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基于多特征的多分类器融合决策印鉴识别

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计算机工程与应用 2004年第34期40卷 215-217页

作者：朱虹李晗辛威邓颖娜西安理工大学信息与自动控制工程学院西安710048

印鉴真伪鉴别的难点在于由于人工加盖印鉴时,用力的不同,媒介的不同会导致真印鉴的差异与伪造印鉴的差异很难提出一个标准进行自动区别。要求识别系统同时具备同类印鉴的鲁棒性及异类印鉴的敏感性。针对这一难点,该文提出了一种基于多... 详细信息

印鉴真伪鉴别的难点在于由于人工加盖印鉴时,用力的不同,媒介的不同会导致真印鉴的差异与伪造印鉴的差异很难提出一个标准进行自动区别。要求识别系统同时具备同类印鉴的鲁棒性及异类印鉴的敏感性。针对这一难点,该文提出了一种基于多特征的多分类器融合决策算法,根据多类特征以及多种分类器的不同特性,获得对真伪印鉴的鉴别。采用Gabor滤波器获得频率特征,采用差图像获得结构特征,采用原图像和极坐标图像的奇异值获得不变量特征。采用支持向量机(SupportVectorMachine,SVM)和Fisher分类器进行融合决策对印鉴进行真伪鉴别。实验表明,该文方法具有很高的真伪鉴别能力。

关键词： Gabor滤波器奇异值分解支持向量机多分类器决策融合

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