检索结果-南通市图书馆

Microstructures and mechanical properties of a commercial Mg-Al-Zn-Mn alloy with various hot-extrusion processes

在线全文

学校读者我要写书评

暂无评论

Rare Metals 2024年第3期43卷 1329-1336页

作者： He Ma Fan-Zhi Meng Qiang Yang Ze-Feng Xie Yuan-Ding Huang xin qiu State Key Laboratory of Rare Earth Resource Utilization Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun130022China School of Materials Science and Engineering Changchun University of Science and TechnologyChangchun130022China MagIC-Magnesium Innovation Center Helmholtz-Zentrum Geesthacht21502GeesthachtGermany Engineering Research Center of Optoelectronic Functional Materials Ministry of EducationChangchun University of Science and TechnologyChangchun130022China

Mg-Al-Zn-Mn(AZ)system alloys have become widely used due to their good castability,excellent formability and outstanding corrosion resistance[1-6].However,their strength is still much lower than that of traditional Mg... 详细信息

关键词： alloys alloy corrosion

A preliminary study of the mechanism of compound hearing loss caused by ototoxic drugs combined with impulse noise

在线全文

学校读者我要写书评

暂无评论

iLABMED 2024年第1期2卷 38-52页

作者： xin qiu Qing‐qing Jiang Wei‐wei Guo Ning Yu Shi‐ming Yang Senior Department of Otolaryngology Head and Neck Surgery Chinese PLA General HospitalChinese PLA Medical SchoolBeijingChina State Key Laboratory of Hearing and Balance Science BeijingChina National Clinical Research Center for Otolaryngologic Diseases BeijingChina Key Laboratory of Hearing Science Ministry of EducationBeijingChina Beijing Key Laboratory of Hearing Impairment Prevention and Treatment BeijingChina Chinese PLA Medical School BeijingChina

Background:Hearing loss(HL)is becoming increasingly common and is more commonly caused by noise,ototoxic substances,or a combination of ototoxic factors.However,so far,few studies have examined the mechanism by which compound factors cause HL.The only relevant study is about occupational ototoxic substances combined with environmental noise at 85-110 dB SPL.In this study,to address the shortcomings of existing research,we innovatively focused on HL induced by loud noise(impulse noise,>160 dB SPL)combined with common ototoxic drugs.The aim of this study was to establish and validate a mature animal model,and then to compare the characteristics of audiology,pathomorphology and molecular features,and to preliminarily predict pathogenesis in compound HL.Materials and Methods:We selected guinea pigs to construct in vivo HL model groups for different extents of exposure,including a blank control group,a single-drug group,a single-impulse noise group,and a compound group.The animal model of the mature compound HL group was established using gentamicin combined with impulse noise.We then performed audio-logical and pathological verification.We analyzed the auditory brainstem response(ABR),pathological morphology of the cochlea,and molecules(including important self-radicals,cytokines,and apoptosis signal trans-duction pathway proteins in the pathogenesis of drug-and noise-induced HL),compared the effect of different extents of exposure on HL,and preliminarily predict the pathogenic mechanism of compound HL.Results:Four groups of animal models were established successfully and verified by audiology and pathology.Regarding audiology,there were no sig-nificant differences in the ABR thresholds before exposure(p>0.05),but differences emerged among the groups after exposure.Notably,after 3,7,and 14 days of exposure,there were significant differences in the ABR thresholds between the compound group and both the drug and noise groups(p<0.01),and after 14 days,the HL of the compound group was much more severe(greater than the li

关键词： auditory brainstem response gentamicin hearing loss impulse noise molecular mechanisms pathomorphology

Microstructures and mechanical properties of as-cast Mg-Sm-Zn-Zr alloys with varying Gd contents

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Magnesium and Alloys 2022年第5期10卷 1220-1234页

作者： Kai Guan Daisuke Egusa Eiji Abe Jinghuai Zhang xin qiu Qiang Yang Jian Meng Department of Materials Science&Engineering The University of TokyoTokyo 113-8656Japan Key Laboratory of Superlight Material and Surface Technology Ministry of EducationCollege of Material Science and Chemical EngineeringHarbin Engineering UniversityHarbin 150001PR China State Key Laboratory of Rare Earth Resource Utilization Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022PR China Research Center for Structural Materials National Institute for Materials ScienceTsukuba 305-0047Japan

The effect of Gd content on the microstructure and tensile properties of as-cast Mg-Sm-Zn-Zr alloy has been systematically investigated.In the Mg-3Sm-0.5Zn-0.5Zr alloy, the intermetallic compounds with multiple morphologies are identified as Mg_(3)Sm phase. In addition to Mg_(3)RE phase, Mg_(5)RE phase originated from Gd addition is observed in Gd-modified alloys. It should be noted that the lattice parameters of all the observed intermetallic compounds are significantly reduced by Zn segregation. The segregation behavior of Zn in Mg_(3)Sm phase is inhibited to some extent by Gd addition due to the electronegativity difference between Sm/Gd and Zn elements. In addition, the increased Gd content effectively leads to much more accumulation of solute atoms in front of the liquid-solid interface during solidification, which can prominently promote nucleation in liquid region and then refine grains. The tensile yield stress of the present alloys is thus improved with increasing Gd addition. Finally, Gd-modified alloys exhibit significantly age-hardening effect, which can be mainly attributed to the high-volume fraction and high density nano-scale precipitates.

关键词： Magnesium alloys Microstructure characterization Mechanical properties Transmission electron microscopy(TEM)

Multiplex intermetallic phases in a gravity die-cast Mg-6.0Zn-1.5Nd-0.5Zr(wt%) alloy

在线全文

学校读者我要写书评

暂无评论

Journal of Magnesium and Alloys 2022年第1期10卷 225-240页

作者： Fanzhi Meng Shuhui Lv Qiang Yang xin qiu Zixiang Yan Qian Duan Jian Meng State Key Laboratory of Rare Earth Resource Utilization Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022China School of Materials Science and Engineering Changchun University of Science and Technology130022China

Components and crystal structures of the intermetallic phases in a gravity die-cast Mg-6.0Zn-1.5Nd-0.5Zr(wt%)alloy were investigated using transmission electron microscopy.The results indicate that this alloy has multiple intermetallic phases and various inner faults.Totally,six eutectoid intermetallic phases,namely W(Mg Nd Zn_(3)),T(Mg_(39)Zn_(55)Nd_(6)),(Mg,Zr)Zn_(2),Z(Mg_(28)Zn_(65)Nd_(7)),H_(2)(Mg_(15)Zn_(70)Nd_(15)),and H1(Mg_(24)Zn_(64)Nd_(11)),were simultaneously observed at grain boundaries,and six precipitates(Z,Mg_(7)Zn_(3),T,Mg_(4)Zn_(7),β_(1)-Mg Zn_(2) and β_(2)-Mg Zn_(2))were found inα-Mg grains.Furthermore,faults like sub-grain boundaries,orientation domains(coherent with the same matching plane but with different orientations),stacking faults and twins were observed in the eutectoid intermetallic phases.Finally,some new orientation relationships between the known intermetallic phases were revealed.This paper can provide new insight into alloy design for Mg-Zn-RE(RE:rare earth)based alloys.

关键词： Magnesium alloys Intermetallic phase Structure Transmission electron microscopy(TEM) Orientation relationship

Uncovering the prominent role of satellite cells in paravertebral muscle development and aging by single-nucleus RNA sequencing

在线全文

学校读者我要写书评

暂无评论

Genes & Diseases 2023年第6期10卷 2597-2613页

作者： xin qiu Hao-Yu Wang Zhen-Yu Yang Li-Ming Sun Shu-Nan Liu Chui-Qin Fan Feng Zhu Department of Spinal Surgery The University of Hong Kong-Shenzhen HospitalShenzhenGuangdong 518000China Department of Orthopedics and Traumatology Li Ka Shing Faculty of MedicineThe University of Hong KongHong Kong SAR 999077China College of Life Sciences University of Chinese Academy of SciencesBeijing 100000China Lars Bolund Institute of Regenerative Medicine Qingdao-Europe Advanced Institute for Life SciencesBGI-QingdaoQingdaoShandong 266000China China Medical University ShenyangLiaoning 110000China Department of Plastic and Reconstructive Surgery Xijing HospitalForth Military Medical UniversityXi'anShaanxi 710000China

To uncover the role of satellite cells(SCs)in paravertebral muscle development and aging,we constructed a single-nucleus transcriptomic atlas of mouse paravertebral muscle across seven timepoints spanning the embryo(day 16.5)to old(month 24)stages.Eight cell types,including SCs,fast muscle cells,and slow muscle cells,were identified.An energy metabolism-related gene set,TCA CYCLE IN SENESCENCE,was enriched in SCs.Forty-two skeletal muscle disease-related genes were highly expressed in SCs and exhibited similar expression patterns.Among them,Pdha1 was the core gene in the TCA CYCLE IN SENESCENCE;Pgam2,Sod1,and Suclg1 are transcription factors closely associated with skeletal muscle energy metabolism.Transcription factor enrichment analysis of the 42 genes revealed that Myod1 and Mef2a were also highly expressed in SCs,which regulated Pdha1 expression and were associated with skeletal muscle development.These findings hint that energy metabolism may be pivotal in SCs development and aging.Three ligand-receptor pairs of extracellular matrix(ECM)-receptor interactions,Lamc1-Dag1,Lama2-Dag1,and Hspg2-Dag1,may play a vital role in SCs interactions with slow/fast muscle cells and SCs self-renewal.Finally,we built the first database of a skeletal muscle single-cell transcriptome,the Musculoskeletal Cell Atlas(http://www.***.tech),which lists 630,040 skeletal muscle cells and provides interactive visualization,a useful resource for revealing skeletal muscle cellular heterogeneity during development and aging.Our study could provide new targets and ideas for developing drugs to inhibit skeletal muscle aging and treat skeletal muscle diseases.

关键词： Niche Paraspinal muscle Satellite cells Senescence Single-nucleus RNA sequencing

Evaluation of a Regional Ensemble Data Assimilation System for Typhoon Prediction

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Advances in Atmospheric Sciences 2022年第11期39卷 1816-1832页

作者： Lili LEI Yangjinxi GE Zhe-Min TAN Yi ZHANG Kekuan CHU xin qiu Qifeng QIAN Key Laboratory of Mesoscale Severe Weather/Ministry of Education School of Atmospheric SciencesNanjing UniversityNanjing 210063China National Meteorological Center China Meteorological AdministrationBeijing 100081China

An ensemble Kalman filter(EnKF) combined with the Advanced Research Weather Research and Forecasting model(WRF) is cycled and evaluated for western North Pacific(WNP) typhoons of year 2016. Conventional in situ data, radiance observations, and tropical cyclone(TC) minimum sea level pressure(SLP) are assimilated every 6 h using an 80-member ensemble. For all TC categories, the 6-h ensemble priors from the WRF/EnKF system have an appropriate amount of variance for TC tracks but have insufficient variance for TC intensity. The 6-h ensemble priors from the WRF/EnKF system tend to overestimate the intensity for weak storms but underestimate the intensity for strong storms. The 5-d deterministic forecasts launched from the ensemble mean analyses of WRF/EnKF are compared to the NCEP and ECMWF operational control forecasts. Results show that the WRF/EnKF forecasts generally have larger track errors than the NCEP and ECMWF forecasts for all TC categories because the regional simulation cannot represent the large-scale environment better than the global simulation. The WRF/EnKF forecasts produce smaller intensity errors and biases than the NCEP and ECMWF forecasts for typhoons, but the opposite is true for tropical storms and severe tropical storms. The 5-d ensemble forecasts from the WRF/EnKF system for seven typhoon cases show appropriate variance for TC track and intensity with short forecast lead times but have insufficient spread with long forecast lead times. The WRF/EnKF system provides better ensemble forecasts and higher predictability for TC intensity than the NCEP and ECMWF ensemble forecasts.

关键词： ensemble Kalman filter typhoon prediction ensemble forecast

在线全文

学校读者我要写书评

暂无评论

数字化赋能、服务型制造与工业低碳转型

技术经济与管理研究 2024年第7期 133-138页

作者：邱信丰江西省社会科学院农业农村发展研究所江西南昌330077 江西财经大学理论经济学博士后流动站江西南昌330013

选取中国投入产出表数据,研究数字化对服务型制造的影响效应,并检验数字化通过服务型制造对工业低碳转型的促进作用。研究表明,数字化显著提升了服务型制造水平,经稳健性和内生性检验后结论依然成立。异质性研究发现,数字化对高碳行业... 详细信息

选取中国投入产出表数据,研究数字化对服务型制造的影响效应,并检验数字化通过服务型制造对工业低碳转型的促进作用。研究表明,数字化显著提升了服务型制造水平,经稳健性和内生性检验后结论依然成立。异质性研究发现,数字化对高碳行业及交通仓储、批发零售等行业服务型制造的促进作用更明显,而对科学技术研究服务等促进作用偏弱。机制研究发现,数字化赋能服务型制造有效推动了工业低碳转型。为此,文章提出夯实数字技术基础、推动数字化与服务型制造深度融合及创新服务型制造赋能工业低碳转型发展模式等建议。

关键词：数字化服务型制造低碳转型投入产出表

在线全文

学校读者我要写书评

暂无评论

基于接受心理的图书馆文创产品设计研究

包装工程 2024年第8期45卷 356-366页

作者：高崇裘欣沈阳航空航天大学沈阳110136

目的基于接受心理对图书馆文创产品设计方法进行研究。方法在图书馆文创产品用户体验影响要素分析的基础上,将图书馆文创产品用户体验过程划分为感官认知、行为交互、价值理解、情感表达四个阶段,通过研究各阶段中用户接受心理的主体性... 详细信息

目的基于接受心理对图书馆文创产品设计方法进行研究。方法在图书馆文创产品用户体验影响要素分析的基础上,将图书馆文创产品用户体验过程划分为感官认知、行为交互、价值理解、情感表达四个阶段,通过研究各阶段中用户接受心理的主体性、主观性、主动性以及期待视野对其体验过程满意度的影响,提出各阶段符合用户接受心理的设计策略,进而形成了基于接受心理的图书馆文创产品设计方法。结论通过辽宁省图书馆文创产品设计实践验证了方法的有效性。基于接受心理进行图书馆文创产品设计,可以更好地把握用户的心理需求,有针对性地进行方案输出,提高用户对文创产品体验的满意度,助力图书馆文创产品的开发与推广。

关键词：接受心理图书馆文创产品设计用户体验心理需求设计流程

大数据背景下饲料企业精准营销的价值及应用策略

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

中国饲料 2024年第4期 113-116页

作者：邱鑫王静信阳涉外职业技术学院河南信阳465550

在大数据时代,互联网与行业的碰撞与融合催生了“互联网+饲料”的新型业态。尤其在国家对农业电子商务发展给予大力扶持的背景下,如何实现饲料企业电子商务的精准营销尤为必要。本文阐述了精准营销在饲料企业电子商务中的价值,并根据精... 详细信息

在大数据时代,互联网与行业的碰撞与融合催生了“互联网+饲料”的新型业态。尤其在国家对农业电子商务发展给予大力扶持的背景下,如何实现饲料企业电子商务的精准营销尤为必要。本文阐述了精准营销在饲料企业电子商务中的价值,并根据精准营销的特点提出相关的应用策略,从而推动饲料企业逐渐向互联网转型,有效解决饲料产品的销量问题。

关键词：大数据精准营销饲料企业电子商务