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Journal of Iron and Steel Research International 2021年第1期28卷 38-45页

作者： xin‑ming ren Bei‑yue Ma Shi‑ming Li Hong‑xia Li Guo‑qi Liu Wen‑gang Yang Fan Qian Shi‑xian Zhao Jing‑kun Yu Key Laboratory for Ecological Metallurgy of Multimetallic Mineral(Ministry of Education) School of MetallurgyNortheastern UniversityShenyang 110819LiaoningChina State Key Laboratory of Advance Refractories Sinosteel Luoyang Institute of Refractories Research Co.Ltd.Luoyang 471039HenanChina

To illuminate the corrosion behavior of MgO-based refractories under electromagnetic field(EMF),herein,the slag corrosion and penetration resistance of MgO–MgAl_(2)O_(4),MgO–CaO,and MgO–C refractories were investigated using the rotary immersion slag resistance test at 1873 K for 1 *** results showed that the order of the good slag resistance of as-tested refractories was MgO–C>MgO–CaO>MgO–MgAl_(2)O_(4).The EMF accelerated the corrosion and penetration of slag to the refractories,which caused the molten slag to be easier into the refractories by natural convection and Marangoni *** addition,the MgO–C refractories did not show an overwhelming advantage in slag resistance because EMF impeded the formation of the dense protection ***,in view of the present results,the MgO–C refractories are still the most promising slag line material for refining furnace among MgO–MgAl_(2)O_(4),MgO–CaO,and MgO–C refractories.

关键词： MgO-based refractory Corrosion Basic slag Electromagnetic field

Recent progress in synthesis of composite powders and their applications in low-carbon refractories

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Journal of Iron and Steel Research International 2022年第7期29卷 1041-1051页

作者： Ji-yuan Luo xin-ming ren Xiao-chuan Chong Dong-hai Ding Bei-yue Ma Guo-qing Xiao Jing-kun Yu College of Materials Science and Engineering Xi’an University of Architecture and TechnologyXi’an 710055ShaanxiChina School of Metallurgy Northeastern UniversityShenyang 110819LiaoningChina

The development of low-carbon refractories is of great significance,but it is limited by the deteriorated properties that resulted from the decreased graphite *** composite powders has proved to be effective in improving the properties of low-carbon *** recent progress in the synthesis of composite powders including modified graphite,nanocarbon-containing composite powders,oxide/non-oxide and non-oxide composite powders and their applications in low-carbon refractories were reviewed,and the future development of composite powder technology was prospected.

关键词： Composite powder Modified graphite Nanocarbon-containing composite powder Oxide/non-oxide Non-oxide Low-carbon refractory

Ankfy1 is dispensable for neural stem/precursor cell development

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Neural Regeneration Research 2016年第11期11卷 1804-1809页

作者： Chao Weng Man Ding Lian-sheng Chang ming-xin ren Hong-feng Zhang Zu-neng Lu Hui Fu Department of Neurology Renmin Hospital of Wuhan University Department of Anatomy and Embryology School of Basic Medical SciencesWuhan University Department of Pathology Central Hospital of Wuhan Hubei-MOST KLOS & KLOBME

There are few studies on the membrane protein Ankfyl. We have found Ankfyl is specifically expressed in neural stem/precursor cells during early development in mice （murine）. To further explore Ankfyl function in neural development, we developed a gene knockout mouse with a mixed Balb/C and C57/BL6 genetic background. Using immunofluorescence and in situ hybridization, neural defects were absent in mixed genetic Ankfyl null mice during development and in adults up to 2 months old. However, Ankfyl gene knockout mice with a pure genetic background were found to be lethal in the C57/BL6 inbred mice embryos, even after seven generations of backcrossing. Polymerase chain reaction confirmed homozygotes were unattainable as early as embryonic day 11.5. We conclude that Ankfyl protein is dispensable in neural stem/precursor ceils, but could be critical for early embryonic murine development, depending on the genetic background.

关键词： nerve regeneration Ankfyl neural development genetic background protein function gene knockout neural stem/precursor cells embryo neural regeneration

Influence of pre-synthesized Al_(2)O_(3)-SiC composite powder from clay on properties of low-carbon MgO-C refractories

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Journal of Iron and Steel Research International 2022年第7期29卷 1080-1088页

作者： Bei-yue Ma xin-ming ren Zhi Gao Fan Qian Zhao-yang Liu Guo-qi Liu Jing-kun Yu Gao-feng Fu Key Laboratory for Ecological Metallurgy of Multimetallic Mineral(Ministry of Education) Shenyang 110819LiaoningChina School of Metallurgy Northeastern UniversityShenyang 110819LiaoningChina State Key Laboratory of Advance Refractories Sinosteel Luoyang Institute of Refractories Research Co.Ltd.Luoyang 471039HenanChina

To improve the properties of low-carbonization of MgO–C refractories,the introduction of composite additives is an effective ***_(2)O_(3)–SiC composite powder was prepared from clay using electromagnetic induction heating and carbon embedded ***,the Al_(2)O_(3)–SiC composite powder synthesized by electromagnetic induction heating at 600 A was added into low-carbon MgO–C refractories(4 wt.%)to improve their *** results showed that when the addition amount of Al_(2)O_(3)–SiC composite powder is within the range of 2.5–5.0 wt.%,the properties of low-carbon MgO–C samples were significantly improved,e.g.,the apparent porosity of 7.58%–8.04%,the bulk density of 2.98–2.99 g cm-3,the cold compressive strength of 55.72–57.93 MPa,the residual strength after three air quenching at 1100°C of 74.86%–78.04%,and the decarburized layer depth after oxidized at 1400°C for 2 h of 14.03–14.87 ***,the idea for the rapid synthesis of Al_(2)O_(3)–SiC composite powder provides an alternative low-carbon MgO–C refractories performance optimization strategy.

关键词： MgO–C refractory Electromagnetic induction heating Al_(2)O_(3)–SiC composite powder Oxidation

Progress of research in the application of ultrasound technology for the treatment of Alzheimer’s disease

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Neural Regeneration Research 2025年第10期20卷 2823-2837页

作者： Qiuquan Cai Lianghui Meng Meina Quan Ling Wang Jing ren Chenguang Zheng Jiajia Yang Dong ming Academy of Medical Engineering and Translational Medicine Tianjin UniversityTianjinChina Innovation Center for Neurological Disorders Xuanwu HospitalCapital Medical UniversityBeijingChina Brain-Computer Interaction and Human-Machine Fusion Haihe Laboratory Tianjin UniversityTianjinChina Tianjin Key Laboratory of Brain Science and Neural Engineering Tianjin UniversityTianjinChina

Alzheimer’s disease is a common neurodegenerative disorder defined by decreased reasoning abilities,memory loss,and cognitive *** presence of the blood-brain barrier presents a major obstacle to the development of effective drug therapies for Alzheimer’s *** use of ultrasound as a novel physical modulation approach has garnered widespread attention in recent *** a safe and feasible therapeutic and drug-delivery method,ultrasound has shown promise in improving cognitive *** article provides a summary of the application of ultrasound technology for treating Alzheimer’s disease over the past 5 years,including standalone ultrasound treatment,ultrasound combined with microbubbles or drug therapy,and magnetic resonance imaging-guided focused ultrasound *** is placed on the benefits of introducing these treatment methods and their potential *** found that several ultrasound methods can open the blood-brain barrier and effectively alleviate amyloid-βplaque *** believe that ultrasound is an effective therapy for Alzheimer’s disease,and this review provides a theoretical basis for future ultrasound treatment methods.

关键词： Alzheimer’s disease blood-brain barrier drugs magnetic resonance imaging-guided focused ultrasound microbubbles scanning ultrasound ultrasound ultrasound stimulation

Effect of bFGF on endogenous NSCs in rat hippocampus with global cerebral ischemia-reperfusion

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Effect of bFGF on endogenous NSCs in rat hippocampus with gl...

Preparation and study of novel mid-to-low-temperature phase-change molten salts

中国神经科学学会第九届全国学术会议暨第五次会员代表大会

作者： ming-xin ren,Yi-Wei GUO,Zhi-Bo FENG~* Department of Anatomy,xinxiang Medical University,xinxiang 453003,China

Objective Study the effect of bFGF on endogenous neural stem cell proliferation,migration and differentiation in rats hippocampus with global brain *** Male Sprague-Dawley rats (250-300 g ) were divided into there groups:sham operation group(A),operation group(B),bFGF group(C).The global brain ischemia-reperfusion models were established,and then the bFGF was injected into the lateral ventricle in group *** doses of 5μl(0.1μg/μl) was administrated before the model operation,and once every two days after *** rat brains were acquired at 3 d,7 d,11 d,15 d with intraperitoneal injection of BrdU 1 d before animal *** and immunohistochemistry were used to observe the pathological changes and the expression of BrdU and Nestin in cerebral hippocampus and ***-PCR was used to measure the NSE mRNA in brain ***(1) HE staining:There were a lot of degenerated and necrotic neurons and the bodies were shrunken with karyopycnosis and chrornatospherite *** group C the number of survival neurons was increased.(2) Immunohistochemistry:In group A,there were few positive cells in hippocampus and cerebral *** with group A,the expression of BrdU and Nestin was increased significantly at 3 day in B,C group,peaked at 7 day in B group and at 11 day in C group,then began to *** with model group,the number of BrdU-positive and Nestin-positive cells were increased significantly at each time point in group C(Prentiated in

关键词： global cerebral ischemia endogenous neural stem cells bFGF rat

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Science China Technological Sciences 2025年

作者： Chenxing ren Yifan WANG xin HE Chenghang ZHENG Xiang GAO State Key Laboratory of Clean Energy Utilization Zhejiang University Institute of Carbon Neutrality Zhejiang University Baima Lake Laboratory Zhejiang University

Molten salts is a promising medium for heat storage and heat transfer due to their advantages of low cost, low steam pressure, high energy storage density and wide temperature range. In this paper, a new phase change mixture of molten salts with KNO3, NaNO3, ZnCl2, NaF, Na2CO3, NaCl, and MgO as materials has been prepared through a plenty of experiments. The experimental results show that the melting point of some molten salts can be reduced to 202.9°C, and the decomposition temperature can reach 701.3°C. In addition, its thermophysical properties, including specific heat, viscosity and thermal stability, were measured and analyzed. The average specific heat of some molten salts is as high as 2.53 J/（g K）, and the average thermal conductivity is as high as 0.77 W/（m K）. In the 4-day short-term thermal stability test, the fluctuation of each parameter is minimal, and the overall thermal physical property is relatively stable. Compared with the traditional phase change molten salt, the new hybrid molten salt has a significantly lower melting point, a further improvement in the decomposition temperature, specific heat and other comprehensive thermophysical properties, and a better overall economy, which has important application value in heat transfer and energy storage.

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Early identification of stroke through deep learning with multi-modal human speech and movement data

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Neural Regeneration Research 2025年第1期20卷 234-241页

作者： Zijun Ou Haitao Wang Bin Zhang Haobang Liang Bei Hu Longlong ren Yanjuan Liu Yuhu Zhang Chengbo Dai Hejun Wu Weifeng Li xin Li School of Computer Science and Engineering Sun Yat-sen UniversityGuangzhouGuangdong ProvinceChina Department of Neurology Guangdong Neuroscience InstituteGuangdong Provincial People’s Hospital(Guangdong Academy of Medical Sciences)Southern Medical UniversityGuangzhouGuangdong ProvinceChina Department of Emergency Medicine Guangdong Provincial People’s Hospital(Guangdong Academy of Medical Sciences)Southern Medical UniversityGuangzhouGuangdong ProvinceChina

Early identification and treatment of stroke can greatly improve patient outcomes and quality of *** clinical tests such as the Cincinnati Pre-hospital Stroke Scale(CPSS)and the Face Arm Speech Test(FAST)are commonly used for stroke screening,accurate administration is dependent on specialized *** this study,we proposed a novel multimodal deep learning approach,based on the FAST,for assessing suspected stroke patients exhibiting symptoms such as limb weakness,facial paresis,and speech disorders in acute *** collected a dataset comprising videos and audio recordings of emergency room patients performing designated limb movements,facial expressions,and speech tests based on the *** compared the constructed deep learning model,which was designed to process multi-modal datasets,with six prior models that achieved good action classification performance,including the I3D,SlowFast,X3D,TPN,TimeSformer,and *** found that the findings of our deep learning model had a higher clinical value compared with the other ***,the multi-modal model outperformed its single-module variants,highlighting the benefit of utilizing multiple types of patient data,such as action videos and speech *** results indicate that a multi-modal deep learning model combined with the FAST could greatly improve the accuracy and sensitivity of early stroke identification of stroke,thus providing a practical and powerful tool for assessing stroke patients in an emergency clinical setting.

关键词： artificial intelligence deep learning diagnosis early detection FAST screening stroke

Molecular dynamics simulations of helium transport through inorganic mineral nanopores

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Science China Earth Sciences 2025年第1期68卷 237-252页

作者： Dandan SONG Ping GUAN Chi ZHANG Jiahao ren School of Earth and Space Sciences Peking University

Helium transport through nanoscale inorganic mineral pores and pore throats is essential for its overall migration. To elucidate helium's transport dynamics within nanopores, we employed equilibrium and non-equilibrium molecular dynamics simulations to investigate helium's static self-diffusion and pressure-driven flow in quartz slit-shaped nanopores. We also introduced water and various gases, including hydrogen, methane, ethane, nitrogen, and carbon dioxide, into the nanopores to assess their influence on helium transport. Our findings indicate minimal helium adsorption on quartz pore surfaces. Under conditions where the pore size is less than 5 nm and the pressure under 10 MPa, environmental factors markedly influence helium diffusion. Large pore sizes, high temperatures, and low gas pressures enhance helium desorption and facilitate faster diffusion. We observed a positive correlation between helium flow velocity and factors such as pore size, pressure gradient, and surface smoothness of the pores. Notably, the presence of pore water and carrier gases in quartz nanopores, which diffuse more slowly than helium, tends to reduce helium surface adsorption and slow its diffusion. Among the carrier gases studied, nitrogen showed similar adsorption capacity, diffusivity, and stability to helium, while carbon dioxide displayed the highest adsorption capacity and the slowest diffusion rate, markedly differing from helium. Based on the simulation results, we concluded that water and carrier gases primarily function as transport mediums in helium migration, moving together with helium. Nitrogen, which shares similar properties with helium, effectively assists in this co-migration process. Conversely, carbon dioxide, due to its high adsorption capacity and slow diffusion, tends to be lost during co-migration. As a result, gas reservoirs with high nitrogen levels and low carbon dioxide levels are more likely to have higher helium concentrations. Additionally, the smaller por

关键词： Helium transport Slit nanopores Molecular dynamics simulations Diffusion Flow carriers

Tailoring Light–Matter Interactions in Overcoupled Resonator for Biomolecule Recognition and Detection

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Nano-Micro Letters 2025年第1期17卷 262-280页

作者： Dongxiao Li Hong Zhou Zhihao ren Cheng Xu Chengkuo Lee Department of Electrical and Computer Engineering National University of SingaporeSingapore 117583Singapore Center for Intelligent Sensors and MEMS(CISM) National University of SingaporeSingapore 117608Singapore

Plasmonic nanoantennas provide unique opportunities for precise control of light–matter coupling in surface-enhanced infrared absorption(SEIRA)spectroscopy,but most of the resonant systems realized so far suffer from the obstacles of low sensitivity,narrow bandwidth,and asymmetric Fano resonance ***,we demonstrated an overcoupled resonator with a high plasmon-molecule coupling coefficient(μ)(OC-Hμresonator)by precisely controlling the radiation loss channel,the resonator-oscillator coupling channel,and the frequency detuning *** observed a strong dependence of the sensing performance on the coupling state,and demonstrated that OC-Hμresonator has excellent sensing properties of ultra-sensitive(7.25%nm^(−1)),ultra-broadband(3–10μm),and immune asymmetric Fano *** characteristics represent a breakthrough in SEIRA technology and lay the foundation for specific recognition of biomolecules,trace detection,and protein secondary structure analysis using a single array(array size is 100×100μm^(2)).In addition,with the assistance of machine learning,mixture classification,concentration prediction and spectral reconstruction were achieved with the highest accuracy of 100%.Finally,we demonstrated the potential of OC-Hμresonator for SARS-CoV-2 *** findings will promote the wider application of SEIRA technology,while providing new ideas for other enhanced spectroscopy technologies,quantum photonics and studying light–matter interactions.

关键词： Plasmonic nanoantennas Light-matter interaction Surface-enhanced infrared absorption Overcoupled Biosensing