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On the Hybrid Power Mean Involving the Two-Term Exponential Sums and Polynomial Character Sums

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Chinese Annals of Mathematics,Series B 2020年第4期41卷 547-558页

作者： Xingxing LV xiaoxue li School of Mathematics Northwest UniversityXi’an 710127China. Faculty of Science Xi’an Aeronautical UniversityXi’an 710077China.

The main purpose of this paper is using the analytic method and the properties of trigonometric sums and character sums to study the computational problem of one kind hybrid power mean involving two-term exponential s... 详细信息

关键词： The two-term exponential sums Kloosterman sums Dirichlet character of polynomials Hybrid power mean Identity

Ras protein participated in histone acetylation-mediated cell cycle control in Physarum polycephalum

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Chinese Science Bulletin 2005年第16期50卷 1721-1725页

作者： li xiaoxue LU Jun ZHAO Yanmei WANG Xiuli HUANG Baiqu Institute of Genetics and Cytology Northeast Normal UniversityChangchun 130024 China

In this paper, we demonstrate that in Physarum polycephalum, a naturally synchronized slime mold, histone deacetylase (HDAC) inhibitor Trichostatin A (TSA), arrestes the cell cycle at the checkpoints of S/G2, G2/M and mitosis exit, and influences the transcription of two ras genes Ppras1 and Pprap1, as well as the Ras protein level. Antibody neu-tralization experiment using anti-Ras antibody treatment showed that Ras protein played an important role in cell cycle checkpoint control through regulation of the level of Cyclin B1, suggesting that Ras protein might be a key factor for histone acetylation-mediated cell cycle regulation in P. polycephalum.

关键词：蛋白质组蛋白乙酰化作用细胞周期

On the Fourth Power Mean of Generalized Three-Term Exponential Sums

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Journal of Mathematical Research with Applications 2015年第1期35卷 92-96页

作者： Xiancun DU xiaoxue li College of Teacher's Education Honghe University School of Mathematics Northwest University

The main purpose of this paper is using estimates for trigonometric sums and properties of congruence to study the computation of one kind of fourth power mean of a generalized three-term exponential sum, and give an ... 详细信息

关键词： generalized three-term exponential sums fourth power mean identity

Cutaneous Hypersensitivity as an Indicator of Visceral Inflammation via C-Nociceptor Axon Bifurcation

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Neuroscience Bulletin 2021年第1期37卷 45-54页

作者： Yehong Fang Shu Han xiaoxue li Yikuan Xie Bing Zhu Xinyan Gao Chao Ma Institute of Basic Medical Sciences Department of Human AnatomyHistology and EmbryologyNeuroscience CenterChinese Academy of Medical SciencesSchool of Basic MedicinePeking Union Medical CollegeBeijing 100005China Department of Physiology Institute of Acupuncture and MoxibustionChina Academy of Chinese Medical SciencesBeijing 100700China Joint Laboratory of Anesthesia and Pain Peking Union Medical CollegeBeijing 100730China

Pain on the body surface can accompany disorders in the deep tissue or internal organs. However, the anatomical and physiological mechanisms are ***, we provided direct evidence of axon bifurcation in primary C-nociceptive neurons that innervate both the skin and a visceral organ. Double-labeled dorsal root ganglion(DRG) neurons and Evans blue extravasation were observed in 3 types of chemically-induced visceral inflammation(colitis, urocystitis, and acute gastritis) rat *** the colitis model, mechanical hypersensitivity and spontaneous activity were recorded in vivo from doublelabeled C-nociceptive neurons in S1 or L6 DRGs. These neurons showed significantly enhanced responses to both somatic stimulation and colorectal distension. Our findings suggest that the branching of C-nociceptor axons contribute to cutaneous hypersensitivity in visceral inflammation. Cutaneous hypersensitivity on certain locations of the body surface might serve as an indicator of pathological conditions in the corresponding visceral organ.

关键词： Visceral inflammation Cutaneous hypersensitivity Axon bifurcation C-nociceptor

Petroleum pitch derived hard carbon via NaCl-template as anode materials with high rate performance for sodium ion battery

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Frontiers of Chemical Science and Engineering 2024年第7期18卷 1-10页

作者： Baoyu Wu Hao Sun xiaoxue li Yinyi Gao Tianzeng Bao Hongbin Wu Kai Zhu Dianxue Cao Key Laboratory of Superlight Materials and Surface Technology of Ministry of Education College of Materials Science and Chemical EngineeringHarbin Engineering UniversityHarbin 150001China Hunan Hongshan New Energy Technology Co. LtdYiyang 413000China

Sodium-ion batteries(SIBs)have garnered significant interest in energy storage due to their similar working mechanism to lithium ion batteries and abundant reserves of sodium *** facile synthesis of a carbon-based anode materials with capable electrochemical performance is key to promoting the practical application of *** this work,a combination of petroleum pitch and recyclable sodium chloride is selected as the carbon source and template to obtain hard carbon(HC)anode for *** times and temperatures are optimized by assessing the sodium ion storage behavior of different HC *** optimized HC exhibits a remarkable capacity of over 430 mAh·g^(-1) after undergoing full activation through 500 cycles at a density of current of 0.1 A·g^(-1).Furthermore,it demonstrates an initial discharge capacity of 276 mAh·g^(-1) at a density of current of 0.5 A·g^(-1).Meanwhile,the optimized HC shows a good capacity retention(170 mAh·g^(-1) after 750 cycles)and a remarkable rate ability(166 mAh·g^(-1) at 2 A·g^(-1)).The enhanced capacity is attributed to the suitable degree of graphitization and surface area,which improve the sodium ion transport and storage.

关键词： petroleum pitch hard carbon sodium-ion batteries high rate recyclable template

Active Fault Tolerant Control of Electric Power Steering System with Sensor Fault 36

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Active Fault Tolerant Control of Electric Power Steering Sys...

*** Continue Tightening Trade Policy on——A review of the establishment of the *** Trade Enforcement Center

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作者： Zhengang Gao liuqing Yang Hongbo Wang xiaoxue li Ordos Institute of Technology Anhui Communications Vocational and Technical College School of Mechanical and Automotive Engineering Hefei University of Technology

ISBN: (纸本)9781538629185

Considering the assist characteristics failure of electric power steering(EPS) system caused by the sensor fault,this paper presents a fault tolerant control strategy based on fault estimation and *** EPS model with torque sensor and the motor current sensor fault is *** the observer technology and the linear matrix inequality,robust sensor fault estimation with H performance index is achieved;the sensor reconstruction is derived from the fault estimation and sensor fault output,the reconstruction value is then used as the input of the EPS system controller to realize fault tolerant *** simulation result in Matlab/Simulink environment shows that:when the common fault of the torque sensor and the current senor occurs,the designed estimation algorithm could estimate sensor faults accurately;While the fault tolerant control can provide approximately equivalent assist performance of fault EPS to the normal one,which promotes the stability and security of EPS to a large extant.

关键词： EPS Fault Estimation Sensor Reconstruction Fault Tolerant Control

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China's Foreign Trade 2012年第5期 64-65页

作者： li xiaoxue Doctoral student inChina Institute for WTO Studies University of International Businessand Economics

*** Barack Obama igned an executive order n February 28,2012 to set p Interagency Trade Enforcement Center(ITEC) in a bid to coordinate with *** rights,and domestic trade laws enforcement matters. This can be seen as a more tightening protectionism sign for *** trade relation especially with China. As stated in the executive order。

关键词：贸易政策执法中国美国审查行政命令国内贸易保护主义

A Bama miniature pig model of monoallelic TSC1 mutation for human tuberous sclerosis complex

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Journal of Genetics and Genomics 2020年第12期47卷 735-742页

作者： xiaoxue li Tingdong Hu Jiying liu Bin Fang Xue Geng Qiang Xiong lining Zhang Yong Jin Xiaorui liu lin li Ying Wang Rongfeng li Xiaochun Bai Haiyuan Yang Yifan Dai Jiangsu Key Laboratory of Xenotransplantation Nanjing Medical UniversityNanjing 211166China Key Laboratory of Targeted Intervention of Cardiovascular Disease Collaborative Innovation Center for Cardiovascular Disease Translational MedicineNanjing Medical UniversityNanjing 211166China Department of Cell Biology Guangdong Provincial Key Laboratory of Bone and Joint Degenerative DiseasesSchool of Basic Medical SciencesSouthern Medical UniversityGuangzhou 510515China State Key Laboratory of Reproductive Medicine Nanjing Medical UniversityNanjing 211166China Shenzhen Xenotransplantation Medical Engineering Research and Development Center Institute of Translational MedicineShenzhen Second People's HospitalFirst Affiliated Hospital of Shenzhen UniversityShenzhen 518035China

Tuberous sclerosis complex(TSC)is a dominant genetic neurocutaneous syndrome characterized by multiple organ *** rodent models bearing a germline mutation in either TSC1 or TSC2 gene have been generated,they do not develop pathogenic lesions matching those seen in patients with TSC because of the significant differences between mice and humans,highlighting the need for an improved large animal model of ***,we successfully generate monoallelic TSC1-modified Bama miniature pigs using the CRISPR/Cas9 system along with somatic cell nuclear transfer(SCNT)*** expression of phosphorylated target ribosomal protein S6 is significantly enhanced in the piglets,indicating that disruption of a TSC1 allele activate the mechanistic target of rapamycin(mTOR)signaling ***,differing from the mouse TSC models reported previously,the TSC1^(+/−)Bama miniature pig developed cardiac rhabdomyoma and subependymal nodules,resembling the major clinical features that occur in patients with *** TSC1^(+/−)Bama miniature pigs could serve as valuable large animal models for further elucidation of the pathogenesis of TSC and the development of therapeutic strategies for TSC disease.

关键词： CRISPR/Cas9 Cardiac rhabdomyosarcoma Subependymal nodules TSC1 Tuberous sclerosis complex

Overexpressing dominant-negative FGFR2-IIIb impedes lung branching morphogenesis in pigs

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Journal of Genetics and Genomics 2018年第3期45卷 147-154页

作者： Qin Chen Bin Fang Ying Wang Chu li xiaoxue li Ronggen Wang Qiang Xiong lining Zhang Yong Jin Manling Zhang Xiaorui liu lin li lisha Mou Rongfeng li Haiyuan Yang Yifan Dai Jiangsu Key Laboratory of Xenotransplantation Nanfing Medical University Nanjing 211166 China Key Laboratory of Targeted intervention of Cardiovascular Disease Collaborative Innovation Center for Cardiovascular Disease Translational MedicineNanjing Medical University Nanjing 211166 China State Key Laboratory of Reproductive Medicine Nanjing Medical University Nanjing 211166 China Shenzhen Xenotransplantation Medical Engineering Research and Development Center Institute of Translational Medicine Shenzhen Second People's Hospital First Affiliated Hospital of Shenzhen University Shenzhen 518035 China

Genetic studies with mouse models have shown that fibroblast growth factor receptor 2-Ⅲb（FGFR2-Ⅲb）plays crucial roles in lung development and differentiation. To evaluate the effect of FGFR2-Ⅲb in pig lung development, we employed somatic cell nuclear transfer（SCNT） technology to generate transgenic pig fetuses overexpressing the transmembrane（dn FGFR2-Ⅲb-Tm） and soluble（dn FGFR2-Ⅲb-HFc） forms of the dominant-negative human FGFR2-Ⅲb driven by the human surfactant protein C（SP-C） promoter,which was specifically expressed in lung epithelia. Eight dn FGFR2-Ⅲb-Tm transgenic and twelve dn FGFR2-Ⅲb-HFc transgenic pig fetuses were collected from three and two recipient sows, *** of FGFR2-Ⅲb in lung epithelia resulted in smaller lobes and retardation of alveolarization in both forms of dn FGFR2-Ⅲb transgenic fetuses. Moreover, the dn FGFR2-Ⅲb-HFc transgenic ones showed more deterioration in lung development. Our results demonstrate that disruption of FGFR2-Ⅲb signaling in the epithelium impedes normal branching and alveolarization in pig lungs, which is less severe than the results observed in transgenic mice. The dn FGFR2-Ⅲb transgenic pig is a good model for the studies of blastocyst complementation as well as the mechanisms of lung development and organogenesis.

关键词： Dominant-negative FGFR2-Ⅲb Lung organogenesis Porcine