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HRCT观察成人永存岩鳞窦

中国医学影像技术 2019年第5期35卷 664-668页

作者：赵鹏飞吕晗李静丁贺宇窦瑞芳管琳娜李丽孟续续代驰航李小帅仇晓妤杨正汉王振常首都医科大学附属北京友谊医院放射科北京100050 巴彦淖尔市医院放射科内蒙古巴彦淖尔015000 沧州中心医院CT科河北沧州610001 大同大学附属医院放射科山西大同037005

目的基于HRCT评估成人永存岩鳞窦(PSS)发生率及其影像学表现。方法回顾性分析接受薄层HRCT检查且双侧颞骨未见异常的708例成年患者资料。基于0.67 mm层厚的标准化重建轴位、冠状位图像,评估有无PSS及其HRCT征象,包括管径、走行位置、有... 详细信息

目的基于HRCT评估成人永存岩鳞窦(PSS)发生率及其影像学表现。方法回顾性分析接受薄层HRCT检查且双侧颞骨未见异常的708例成年患者资料。基于0.67 mm层厚的标准化重建轴位、冠状位图像,评估有无PSS及其HRCT征象,包括管径、走行位置、有无局部团状扩张、有无周围骨壁缺失、有无盂后孔,分析不同性别、年龄组间PSS发生率差异。结果本组708例(1 416侧)中,PSS发生率为10.59%(150/1 416),平均管径为(1.29±0.58)mm。女性PSS发生率为12.64%(92/728),男性为8.43%(58/688),差异有统计学意义(P=0.010);同一性别不同侧别间PSS发生率差异均无统计学意义(男性:P=0.583,女性:P=0.372)。18～29岁组、30～39岁组、40～49岁组、50～59岁组、60～69岁组组间PSS发生率差异均无统计学意义(P均>0.05),≥70岁组较其他年龄组发生率降低(P均<0.05)。150侧PSS中,24.67%(37/150)走行于岩鳞隔内,75.33%(113/150)走行于岩鳞隔外侧骨沟;47.33%(71/150)可见盂后孔形成,36.67%(55/150)水平向外走行至皮下,10.67%(16/150)垂直向下至颞下颌关节窝;2.67%(4/150)与周围颞骨气房间骨壁缺失;4.67%(7/150)局部呈血管团状扩张。结论 HRCT可显示成人岩鳞窦;颅底或耳部术前需仔细观察,以避免医源性损伤。

关键词：岩鳞窦盂后孔颞骨体层摄影术,X线计算机变异

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番石榴多糖化学与生物活性研究进展

食品研究与开发 2024年第10期45卷 209-216页

作者：许凯博梁钰婵黄小帅芦昕蒂秦赫婕李莉娅东北大学生命科学与健康学院辽宁沈阳110169 辽宁省生物资源开发利用重点实验室辽宁沈阳110169

番石榴(Psidium guajava)为桃金娘科植物,在全球热带及亚热带地区广泛种植。番石榴具有良好的食用和药用价值,长期被用于腹泻、糖尿病等疾病的辅助治疗。多糖是番石榴中的重要活性成分,具有抗氧化、抗肿瘤、抗炎、调节免疫、降血糖、改... 详细信息

番石榴(Psidium guajava)为桃金娘科植物,在全球热带及亚热带地区广泛种植。番石榴具有良好的食用和药用价值,长期被用于腹泻、糖尿病等疾病的辅助治疗。多糖是番石榴中的重要活性成分,具有抗氧化、抗肿瘤、抗炎、调节免疫、降血糖、改善肠道微生态等作用。该文对已报道的番石榴多糖提取方法、结构表征及生物活性相关研究进行梳理与总结,以期为番石榴及其多糖类成分在食品及医药领域的进一步开发利用提供参考和借鉴。

关键词：番石榴多糖提取工艺结构表征生物活性

Is there a great unconformity between Xiamaling and Longshan formations in the North China Craton?

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Science China Earth Sciences 2023年第5期66卷 959-984页

作者： Hongwei KUANG Nan PENG Yongqing liU Yuchong WANG Mingming CUI xiaoshuai CHEN Dawei QIAO Keining QI Institute of Geology Chinese Academy of Geological SciencesBeijing100037China School of Earth Science and Mapping Engineering China University of Mining and Technology(Beijing)Beijing100083China School of Resource and Environmental Engineering Hefei University of TechnologyHefei230009China

The existence of a 0.3 Ga"great unconformity"between the Mesoproterozoic"Undefined System"Xiamaling Formation and the"Neoproterozoic"Longshan Formation has long been *** this study,stratigraphy,sedimentology,detrital zircon dating,lithium isotope,and major and trace elements were applied to systematically analyze their *** demonstrate that coarse to fine sandstone-mudstone normal cycles with different grades and thicknesses exist from the Xiamaling to the Longshan *** succession formed from a restricted platform with lagoon-shallow marine shelf-tidal flat-beach and tidal shoal developing in ascending *** pebbly sandstone at the bottom of the Long shan Formation does not have the properties of basal conglomerate with tectonic *** youngest detrital zircon is older than 1.6 Ga for the Long shan Formation and overlying Jing'eryu Formation *** addition,no(zircon)provenance has been found from the large igneous province of 1.32-1.2 Ga in Xiamaling ***δ^(7)li isotope values exhibit a gradually increasing *** li content and CIA(Chemical index of alteration)gradually decreases from the top of the Xiamaling Formation to the lower part of the Long shan ***,as K_(2)O/Al_(2)O_(3)and FeO/Fe_(2)O_(3)decreases,Na_(2)O/Al_(2)O_(3)increases,and li/Al,V/Cr,and V/(V+Ni)fluctuates *** the boundary,the Ce/Ce^(*)and Eu/Eu^(*)show positive and negative anomalies,***,the Rb/Sr and Al/Si values decrease,and U/Th values *** indicates that the geochemistry of the weathering crust at the interface of the Xiamaling Formation-Long shan Formation is not ***,it indicates a weakening of continental weathering intensity from the bottom to the top of the *** results do not support the existence of a large unconformity between the Xiamaling and the Longshan ***,it is suggested that the Long shan Formation-Ji

关键词： North China Craton Mesoproterozoic Transition period Unconformity Continuous sedimentation

Research and Application of In-seam Seismic Survey Technology for Disaster-causing Potential Geology Anomalous Body in Coal Seam

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Acta Geologica Sinica(English Edition) 2020年第1期94卷 10-26页

作者： TENG Jiwen li Songying JIA Mingkui liAN Jie liU Honglei liU Guodong WANG Wei Volker SCHAPE FENG Lei YAO xiaoshuai WANG Kang YAN Yafen ZHANG Wanpeng Institute of Geology and Geophysics Chinese Academy of SciencesBeijing 100029China Jilin University Changchun 130026China University of Chinese Academy of Sciences Beijing 100049China Research Institute Henan Energy&Chemical Industry Group Co.Ltd.Zhengzhou 450046China Henan Energy&Chemical Industry Group Co. Ltd.Zhengzhou 450046China Yima Coal Industry Group Co.Ltd. Yima 472300China College of Geosciences and Surveying Engineering China University of Mining and Technology-BeijingBeijing 100083China University of Illinois at Urbana-Champaign Champaign 61801USA Geological Institute China Earthquake AdministrationBeijing 100029China Institute of Geographic Science and Natural Resources Research Chinese Academy of ScienceBeijing 100101China DMT GmbH&Co.KG Essen 45307Germany School of Resource&Environment Henan Polytechnic UniversityJiaozuo 454003China Henan University of Science and Technology Luoyang 471000 China

In order to effectively detect potential geology anomalous bodies in coal bearing formation,such as coal seam thickness variation,small faults,goafs and collapse columns,and provide scientific guidance for safe and efficient mining,the SUMMIT-II EX explosion-proof seismic slot wave instrument,produced by German DMT Company,was used to detect the underground channel wave with the help of transmission method,reflection method and transflective *** area detection experiment in mining face had been carried out thanks to the advantage of channel wave,such as its great dispersion,abundant geology information,strong anti-interference ability and long-distance *** experimental results showed that:(1)Coal seam thickness variation in extremely unstable coal seam has been quantitatively interpreted with an accuracy of more than 80%generally;(2)The faults,goafs and collapse columns could be detected and predicted accurately;(3)Experimental detection of gas enrichment areas,stress concentration regions and water inrush risk zone has been collated;(4)A research system of disaster-causing geology anomalous body detection by in-seam seismic survey has been built,valuable and innovative achievements have been *** of innovation obtained for the first time in this study indicated that it was more effective to detect disaster-causing potential geology anomalies by in-seam seismic survey than by ground seismic *** had significant scientific value and application prospect under complex coal seam conditions.

关键词： in-seam seismic survey technology(ISS) disaster-causing potential geology anomalous body dispersion feature mine geophysical prospecting quantitative interpretation

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恶性外耳道炎影像学表现及预后

中国医学影像技术 2020年第11期36卷 1620-1623页

作者：李小帅邢洁赵鹏飞仇晓妤丁贺宇谢静彭哲龚树生杨正汉王振常首都医科大学附属北京友谊医院放射科北京100050 首都医科大学附属北京友谊医院耳鼻咽喉头颈外科北京100050 河北医科大学第一医院心脏超声科河北石家庄050031

目的分析恶性外耳道炎(MEO)的影像学表现及其预后。方法回顾性分析13例经病理确诊的MEO患者的临床及影像学资料。结果MEO主要临床症状包括耳痛(13/13,100%)、外耳道流脓(10/13,76.92%)及听力下降(5/13,38.46%)。HRCT主要表现为外耳道和... 详细信息

目的分析恶性外耳道炎(MEO)的影像学表现及其预后。方法回顾性分析13例经病理确诊的MEO患者的临床及影像学资料。结果MEO主要临床症状包括耳痛(13/13,100%)、外耳道流脓(10/13,76.92%)及听力下降(5/13,38.46%)。HRCT主要表现为外耳道和中耳鼓室内异常软组织影及周围骨质受累,13例(13/13,100%)外耳道和10例(10/13,76.92%)中耳鼓室见异常软组织影,7例(7/13,53.85%)颞骨鼓部、9例(9/13,69.23%)岩鼓裂、7例(7/13,53.85%)茎突、6例(6/13,46.15%)乳突、3例(3/13,23.08%)下颌骨髁突、3例(3/13,23.08%)颈静脉孔见溶骨性骨质破坏。MRI表现为外耳道和中耳鼓室及周围软组织受累,8例(8/8,100%)外耳道、7例(7/8,87.50%)中耳鼓室、8例(8/8,100%)乳突、7例(7/8,87.50%)颞下颌关节、7例(7/8,87.50%)颞下窝、8例(8/8,100%)咽旁间隙、5例(5/8,62.50%)腮腺平扫可见异常软组织信号,增强后明显强化;其中7例颅内侵犯(7/8,87.50%),表现为增强后脑膜增厚并明显强化;4例(4/8,50.00%)面神经增强后明显强化。治疗后随访2~39个月,11例(11/13,84.62%)临床症状明显改善。结论MEO影像学表现具有一定特征性,经积极治疗后预后较好。

关键词：外耳道炎体层摄影术,X线计算机磁共振成像预后

Super-resolution fluorescence-assisted diffraction computational tomography reveals the threedimensional landscape of the cellular organelle interactome

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light(Science & Applications) 2020年第1期9卷 1889-1903页

作者： Dashan Dong xiaoshuai Huang liuju li Heng Mao Yanquan Mo Guangyi Zhang Zhe Zhang Jiayu Shen Wei liu Zeming Wu Guanghui liu Yanmei liu Hong Yang Qihuang Gong Kebin Shi liangyi Chen State Key Laboratory for Mesoscopic Physics and Frontiers Science Center for Nano-optoelectronics School of PhysicsPeking UniversityBeijing 100871China Collaborative Innovation Center of Extreme Optics Shanxi UniversityTaiyuanShanxi 030006China State Key Laboratory of Membrane Biology Beijing Key Laboratory of Cardiometabolic Molecular MedicineInstitute of Molecular MedicinePeking UniversityBeijing 100871China School of Mathematical Sciences Peking UniversityBeijing 100871China School of Software and Microelectronics Peking UniversityBeijing 100871China State Key Laboratory of Stem Cell and Reproductive Biology Institute of ZoologyChinese Academy of SciencesBeijing 100101China University of Chinese Academy of Sciences Beijing 100049China National Laboratory of Biomacromolecules Chinese Academy of Sciences Center for Excellence in BiomacromoleculesInstitute of BiophysicsBeijing 100101China Institute for Brain Research and Rehabilitation(IBRR) Guangdong Key Laboratory of Mental Health and Cognitive ScienceSouth China Normal UniversityGuangzhouChina Collaborative Innovation Center of Quantum Matter Peking UniversityBeijing 100871China PKU-IDG/McGovern Institute for Brain Research Beijing 100871China

The emergence of super-resolution(SR)fluorescence microscopy has rejuvenated the search for new cellular ***,SR fluorescence microscopy achieves high contrast at the expense of a holistic view of the interacting partners and surrounding ***,we developed SR fluorescence-assisted diffraction computational tomography(SR-FACT),which combines label-free three-dimensional optical diffraction tomography(ODT)with two-dimensional fluorescence Hessian structured illumination *** ODT module is capable of resolving the mitochondria,lipid droplets,the nuclear membrane,chromosomes,the tubular endoplasmic reticulum,and *** dual-mode correlated live-cell imaging for a prolonged period of time,we observed novel subcellular structures named dark-vacuole bodies,the majority of which originate from densely populated perinuclear regions,and intensively interact with organelles such as the mitochondria and the nuclear membrane before ultimately collapsing into the plasma *** work demonstrates the unique capabilities of SR-FACT,which suggests its wide applicability in cell biology in general.

关键词： landscape illumination partner

一种改进变步长LMS算法及其在系统辨识中的应用

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仪器仪表学报 2007年第7期28卷 1340-1344页

作者：李竹杨培林行小帅山西师范大学物理与信息工程学院临汾041004

在分析传统LMS算法及变步长LMS的基础上,本文提出了一种改进的变步长LMS算法并应用于系统辨识。新算法利用瞬时误差的四次方和遗忘因子共同来调整步长,进一步解决了收敛时间和稳态误差的矛盾。将新算法应用到系统辨识中时,与传统LMS算... 详细信息

在分析传统LMS算法及变步长LMS的基础上,本文提出了一种改进的变步长LMS算法并应用于系统辨识。新算法利用瞬时误差的四次方和遗忘因子共同来调整步长,进一步解决了收敛时间和稳态误差的矛盾。将新算法应用到系统辨识中时,与传统LMS算法和变步长LMS算法相比,仿真表明新算法有更快的收敛速率。

关键词： LMS算法变步长遗忘因子系统辨识

Distinct prognostic roles of S100 mRNA expression in hepatocellular carcinoma

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Distinct prognostic roles of S100 mRNA expression in hepatoc...

A Device for Measuring High-TC Superconductor Transition Temperature with Electric Transport and AC Susceptibility Methods Based on Small Cryocooler Cooling

2021年中国肿瘤标志物学术大会暨第十五届肿瘤标志物青年科学家论坛

作者： Xiaoyan Yang Xueqin lin Peng li xiaoshuai Zhou Department of Pediatrics The Affiliated Hospital of Guizhou Medcial University 贵州医科大学

Objective: Hepatocellular carcinoma is still one of the malignant tumors with high mortality. Therefore,it’s urgent to identify the potential prognostic markers to monitor and intervene in hepatocellular *** pieces of evidence have suggested that S100 proteins are closely associated with the progression of various cancers. However, the relationship between a lot of S100 families and hepatocellular carcinoma is still unknown. In this study, we further explore the prognosis value of each S100 member in hepatocellular carcinoma ***: The relevance of individual S100 mRNA expression to OS was accessed on a database that was developed using gene-chip or RNA sequencing data with clinical information of space patients downloaded from Gene Expression Omnibus(GEO) and the Cancer Genome Atlas(TCGA). Briefly, 21 individual members of the S100 family were entered into the Kaplan Meier platter database to obtain the survival plots. HR(hazard ratio), 95%CI(confidence intervals), and logrank P value were provided. P-value of link between the relapse-free survival and the S100 *** S100 A1, S100 A10 and S100 A13, high mRNA expression of those S100 members were correlated to lower relapse-free survival. For S100 A4, S100 A5, S100 A11, S100 B, S100 Z, and S100 G, their mRNA expression levels were associated with longer relapse-free survival. Then, we evaluated the prognosis roles of S100 members in different hepatocellular carcinoma patients, including the hepatocellular carcinoma patients, Asian hepatocellular carcinoma patients and pat

关键词： prognosis hepatocellular carcinoma S100 family

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A Device for Measuring High-TC Superconductor Transition Tem...