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诊断切点的改变对中国高血压、高血脂、高血糖患病率的影响

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中华预防医学杂志 2017年第5期51卷 369-377页

作者：扈学俸韩笑然杨祖耀胡永华唐金陵香港中文大学公共卫生及基层医疗学院 999077 北京大学公共卫生学院香港中文大学深圳研究院深圳卫生风险分析重点实验室 999077 加拿大渥太华大学生物学系

目的高血压、高血脂和高血糖是可能引起心血管疾病并最终导致死亡的三种常见慢性病.20世纪80年代以来,中国高血压、高血脂和高血糖患者人数激增且尚无减缓的趋势,有关危险因素上升是重要原因,但由于在此过程中诊断切点下调过,危险因素... 详细信息

目的高血压、高血脂和高血糖是可能引起心血管疾病并最终导致死亡的三种常见慢性病.20世纪80年代以来,中国高血压、高血脂和高血糖患者人数激增且尚无减缓的趋势,有关危险因素上升是重要原因,但由于在此过程中诊断切点下调过,危险因素上升可能不是患病率上升的唯一解释.本研究旨在估计诊断标准变化对这些疾病患病率影响的大小.方法利用2002和2009年具有中国代表性的成年人健康调查数据（分别包括145254和8813名调查对象）,根据2000年前后新、旧两种诊断标准[＂新、旧＂切点：高血压：140/90和160/95 mmHg（1 mmHg=0.133 kPa）;高血脂：5.7和6.2 mmol/L;高血糖：7.0和7.8 mmol/L],分别估计高血压、高血脂和高血糖患病率及其他相关指标,以及诊断切点改变对它们的影响.并使用2000年全国普查人口的年龄、性别和城乡分布进行标化,估计诊断切点改变对全国患病率的影响,并对不同年份的患病率进行比较.结果根据＂旧标准＂,2002年我国成年人高血压、高血脂和高血糖的标化患病率分别为8.21%、1.71%和1.43%,＂新标准＂下分别为19.18%、3.53%和2.66%;根据＂旧标准＂,2009年三种疾病的患病率分别为11.89%、9.34%和4.29%,＂新标准＂下分别为24.78%、18.36%和6.55%.由于采纳新的诊断标准,2002年三种疾病的总患病人次数增加了124%,2009年增加了95%.初步估计,从2002到2009年,因诊断标准改变导致全国增加的总患病人次数高达3.59亿.如果这三种疾病全部得到治疗,每年新增的药物费用总计2710亿,占2010年政府卫生总投入4800亿的56%.结论中国约50%的高血压、高血脂和高血糖患病率可归因于诊断切点的降低.西方国家的诊断标准不一定直接适用于中国的实际,因诊断标准修订所引起的慢性病负担的＂增加＂应引起决策者和指南制定者的重视.在确定治疗切点时,除了治疗的效果、不良反应及费用之外,还应考虑现有资源的多寡以及患者的需要和价值观.

关键词：高血压血脂异常高血糖症患病率过度诊断

Cl-induced passivity breakdown in α-Fe_(2)O_(3)(0001), α-Cr_(2)O_(3)(0001),and their interface: A DFT study

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Journal of Materials Science & Technology 2022年第34期129卷 70-78页

作者： xiaoran Yin Haitao Wang En-Hou han CAS Key Laboratory of Nuclear Materials and Safety Assessment Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China School of Materials Science and Engineering University of Science and Technology of ChinaShenyang 110016China Institute of Corrosion Science and Technology Guangzhou 510530China

The presence of chloride ions is the critical factor of passivity breakdown of the protective film and eventually leads to localized corrosion. However, the mechanism and the role of chlorides in these processes are still controversial. Hematite and chromia are generally believed to be the major components of outer and inner oxide layers on stainless steels. In the present paper, a comparative study of Cl ingress into pristine and defective α-Fe_(2)O_(3)(0001) surface, α-Cr_(2)O_(3)(0001) surface, along with their interface, was conducted using density functional theory. Vacancy formation energy calculation confirms good stability of α-Cr_(2)O_(3)and high reactive activity of the interface region. Cl inserts into an O vacancy is energetically more favorable than Fe vacancy and interstitial site, demonstrating Cl-induced degradation complies with the ion exchange model. Transition state search for Cl diffusion through O vacancies shows α-Cr_(2)O_(3)is more protective than α-Fe_(2)O_(3), while the interface region is the weak point of the duplex passive film.

关键词： Hematite Chromia DFT+U Interface Cl-induced depassivation

Study on the effect of pressure on the equilibrium and stability of the solid-liquid interface in solidification of binary alloys

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Science China(Technological Sciences) 2011年第2期54卷 479-483页

作者： HUANG xiaoran han ZhiQiang LIU BaiCheng Key Laboratory for Advanced Materials Processing Technology Ministry of Education Tsinghua University Beijing 100084 China State Key Laboratory of Automotive Safety and Energy Tsinghua University Beijing 100084 China

The equilibrium of the solid-liquid interface in pressurized solidification process of binary alloys was studied using the Gibbs theory, and the stability of the solid-liquid interface was discussed based on the consideration of the effects of pressure on the diffusion coefficient, the interface growth rate and tile equilibrium liquid composition. A mathematical description of the equi- librium status, the relationship of temperature, pressure, composition and interfacial tension was obtained, and further, a mathematical representation of the curvature radius of solid-liquid interface was developed, which facilitates a thorough understanding of the controlled variables of the interfacial stability.

关键词： pressurized solidification binary alloy interfacial equilibrium interfacial stability

Distributed Beamforming Based Wireless Power Transfer:Analysis and Realization

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Tsinghua Science and Technology 2020年第6期25卷 758-775页

作者： xiaoran Fan han Ding Yanyong Zhang Wade Trappe Zhu han Rich Howard the Wireless Information Network Laboratory(WINLAB) Rutgers UniversityNew BrunswickNJ 08901USA the Department of Computer Science and Technology Xi'an Jiaotong UniversityXi'an 710049China the Department of Computer Science and Technology University of Science and Technology of ChinaHefei 230052China the Department of Electrical and Computer Engineering University of HoustonHoustonTX 77004USA.

This paper presents a new Wireless Power Transfer(WPT)approach by aligning the phases of a group of spatially distributed Radio Frequency(RF)transmitters(TX)at the target receiver(RX)*** approach can transfer energy over tens of meters and even to targets blocked by *** to popular beamforming based WPTs,our approach leads to a drastically different energy density distribution:the energy density at the target receiver is much higher than the energy density at other *** to this unique energy distribution pattern,our approach offers a safer WPT solution,which can be potentially scaled up to ship a higher level of energy over longer ***,we model the energy density distribution and prove that our proposed system can create a high energy peak exactly at the target *** we conduct detailed simulation studies to investigate how the actual energy distribution is impacted by various important system parameters,including number/topology of transmitters,transmitter antenna directionality,the distance between receiver and transmitters,and environmental ***,we build an actual prototype with 17 N210 and 4 B210 Universal Software Radio Peripheral(USRP)nodes,through which we validate the salient features and performance promises of the proposed system.

关键词： Wireless Power Transfer(WPT) distributed beamforming wireless network

Effect of acupuncture on rabbit bladder with urodynamic indexes

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Journal of Traditional Chinese Medicine 2013年第1期33卷 103-108页

作者： Xianjun Meng Jing han xiaoran Ye Xiaoqing Huang Department of Traditional Chinese Medicine Medical School of Xiamen University Fujian Institute of Traditional Chinese Medicine

OBJECTIVE： To study the effect of acupuncture on rabbit bladder with urodynamic indexes. METHODS： New Zealand male rabbits were divid ed into control group, model group, treatment group 1 treated by acupuncture at Shenshu （BL 23） and treatment group 2 treated by acupuncture at Zhongji （CV 3）. The urine dynamic parameters through the urethral catheter were detected in each group in order： fluctuation of pressure at fill ing phase of urinary bladder and flow rate in urina tion phase, which were used as quantification in dexes of urinary bladder function. The urinary blad der abnormal model was prepared by administra tion of cholinergic stimulant; Regulatory effects of acupuncture at Shenshu （BL 23） and Zhongji （CV 3） on the abnormal state of the urinary bladder were respectively observed. RESULTS： 1） In the filling phase of urinary bladder and in the urination phase, the intravesical pres sure wave in infilling （IPWI） and intravesical dis charge rate （IDR） could be respectively recorded. 2） IPWI and IDR could become abnormality by neo stigmine methyl sulfate [stability type IPWh the con trol group （n=20, 80%） vs the model group （n=15, 14.3%）, P〈0.01; IDR and time regression equation： the control group （n=20, y=24.3 0.878x） vs the model group （n=15, y=40.0 5.15x）, P〈0.01]. 3） Ab normal IPWI＇s could be normalized respectively by acupuncture at Shenshu （BL 23） and Zhongji （CV 3） [the stability type IPWl wave： the model group （n= 2, 14.3%） vs the treatment group 1 （n=3, 30%）, P〉 0.05; the instability type IPWl wave： the model group （n=13, 85.7%） in vs the treatment group 2 （n=6, 60%）, P〉0.05]; 4） Abnormal IDR also could be turned to normality by acupuncture at Shenshu （BL 23） and Zhongji （CV 3）, respectively [IDR and the time regression equation： the model group （n=15, y=40.0 5.15x） vs the treatment group 1 （n=10, y= 18.9 0.499x）, P〈0.01; the model group （n=15, y= 40.0 5.15x） vs the treatment group 2 （n=10, y= 17.5 0.251x）, P〈0.01]. CONCLUSION： 1） Urodynamic indexes

关键词： Urodynamics Acupuncture Point BL23 (Shenshu) Point CV 3 (Zhongji) Voiding dysfunction

Triboelectric nanogenerators:the beginning of blue dream

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Frontiers of Chemical Science and Engineering 2023年第6期17卷 635-678页

作者： Wanli Wang Dongfang Yang xiaoran Yan Licheng Wang han Hu Kai Wang College of Electrical Engineering Weihai Innovation Research InstituteQingdao UniversityQingdao 266071China State Key Laboratory of Heavy Oil Processing College of Chemistry and Chemical EngineeringChina University of Petroleum(East China)Qingdao 266580China Xi’an Traffic Engineering Institute Xi’an 710300China School of Information Engineering Zhejiang University of TechnologyHangzhou 310023China

Wave energy is inexhaustible renewable *** full use of the huge ocean wave energy resources is the dream of mankind for hundreds of ***,the utilization of water wave energy is mainly absorbed and transformed by electromagnetic generators(EMGs)in the form of mechanical ***,waves usually have low frequency and uncertainty,which means low power generation efficiency for ***,in this slow current and random direction wave case,the triboelectric nanogenerator(TENG)has a relatively stable output power,which is suitable for collecting blue *** article summarizes the main research results of TENG in harvesting blue ***,based on Maxwell’s displacement current,the basic principle of the nanogenerator is ***,four working modes and three applications of TENG are introduced,especially the application of TENG in blue *** currently used in blue energy harvesting is divided into four categories and discussed in *** TENG harvests water wave energy,it is meaningless if it cannot be ***,the modular storage of TENG energy is *** output power of a single TENG unit is relatively low,which cannot meet the demand for high ***,the networking strategy of large-scale TENG is further ***’s energy comes from water waves,and each TENG’s output has great randomness,which is very unfavorable for the energy storage after large-scale TENG *** this basis,this paper discusses the power management methods of *** addition,in order to further prove its economic and environmental advantages,the economic benefits of TENG are also ***,the development potential of TENG in the field of blue energy and some problems that need to be solved urgently are briefly summarized.

关键词： blue energy triboelectric nanogenerator water wave energy networking strategy micro nano-energy self-powered devices

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甜叶菊茎叶分离机设计

农业技术与装备 2020年第10期 28-29页

作者：张博周繁韩晓冉焦秀芬马志凯李浩河北农业大学机电工程学院河北保定071001 河北省农业项目规划中心河北石家庄050011 河北省曲周县农业农村局河北曲周057250

甜叶菊茎叶分离机可实现甜叶菊机械化茎叶分离即脱叶功能。通过该机可以大幅提高作业效率、节约人工成本,改变传统人力敲打脱叶效率低、作业强度大、脱叶不干净留的不足,具有较好的推广价值。

关键词：脱叶茎叶分离设计甜叶菊

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优质高产夏谷新品种比较试验

天津农业科学 2020年第12期26卷 26-29页

作者：刘建军韩晓冉焦秀芬刘红亮方路斌河北东粮农业科技股份有限公司河北省杂粮产业技术研究院河北曲周057250 曲周县农业农村局河北曲周057250 邯郸市农业科学院河北邯郸056000

对筛选出的12个夏谷新品种进行了品种比较试验。结果表明,有6个品种产量较对照‘衡谷36’增产,增产幅度为3.86%~36.05%,产量由高到低依次为‘保谷935’、‘保谷22’、‘豫谷35’、‘张杂谷16’、‘张杂谷18’和‘冀谷39’。增产品种抗... 详细信息

对筛选出的12个夏谷新品种进行了品种比较试验。结果表明,有6个品种产量较对照‘衡谷36’增产,增产幅度为3.86%~36.05%,产量由高到低依次为‘保谷935’、‘保谷22’、‘豫谷35’、‘张杂谷16’、‘张杂谷18’和‘冀谷39’。增产品种抗谷锈病,中抗谷瘟病和纹枯病,无倒伏,综合表现较好。

关键词：谷子品种比较试验产量性状

N-carbamoylglutamate improves lipid metabolism, inflammation, and apoptosis responses in visceral adipocytes of Japanese seabass (Lateolabrax japonicus), in vivo and in vitro

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Animal Nutrition 2021年第3期7卷 707-715页

作者： Haoyan Huang xiaoran Zhang Xiaofang Liang Xiufeng Wu Xu Gu Juan han Min Xue National Aquafeed Safety Assessment Center Feed Research InstituteChinese Academy of Agricultural SciencesBeijing100081China Institute of Food and Nutrition Development Ministry of Agriculture and Rural AffairsChina Feed Processing Innovation Team Feed Research InstituteChinese Academy of Agricultural SciencesBeijing100081China

This study applied in vivo and in vitro methods to investigate the effect of dietary N-carbamoylglutamate(NCG)on lipid metabolism,inflammation and apoptosis related-gene expression in visceral adipose tissue and isolated adipocytes of Japanese seabass(Lateolabrax japonicus).A basal diet and a test diet supplemented with 720 mg/kg NCG were fed to the fish for 10 *** the growth trial,no mortality and no significant differences in growth performance were observed in fish between the 2 groups(P>0.05).Plasma Arg content and mRNA level of argininosuccinate synthetase(ASS)in adipose tissue were significantly increased,which indicated that NCG inclusion promoted endogenous Arg ***,the potential effects of NCG treatment on lipid metabolism-related genes expression were studied through in vivo and in vitro *** the present study,we successfully established a primary adipocytes culture system and isolated pre-adipocytes in vitro of Japanese seabass for the first *** the results in vivo and in vitro showed that NCG treatment decreased the mRNA levels of genes related to adipogenesis(fatty acid synthase,FASN),cholesterol synthesis(3-hydroxy-3-methylglutaryl-CoA reductase,HMGCR)and fat deposition(lipoprotein lipase[LPL]and leptin),which revealed the underlying mechanism of NCG on reducing fat *** results of this study demonstrated that NCG inclusion reduced the expression of inflammatory and apoptosis cytokines markedly in vivo and in *** conclusion,NCG did exert beneficial effects on ameliorating adipo-genesis,inflammation and apoptosis via promoting Arg endogenous synthesis in Japanese seabass.

关键词： N-Carbamylglutamate Visceral adipose and adipocytes Lipid metabolism Inflammatory and apoptosis Lateolabrax japonicus