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A thermo-responsive rewritable plasmonic bio-memory by regulating single core-satellite gold nanocluster dissociation

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Nano Research 2024年第8期17卷 7275-7282页

作者： Wen Zhang yi Wang Yamin Wang xiaomei Lu Weibing Wu Quli Fan Lei Zhang State Key Laboratory of Organic Electronics and Information Displays&Institute of Advanced Materials(IAM) Nanjing University of Posts&TelecommunicationsNanjing 210023China Jiangsu Co-Innovation Center for Efficient Processing and Utilization of Forest Resources College of Light Industry and Food EngineeringNanjing Forestry UniversityNanjing 210037China Zhengzhou Institute of Biomedical Engineering and Technology Zhengzhou 450001China Key Laboratory of Flexible Electronics(KLOFE) Institute of Advanced Materials(IAM)&School of Flexible Electronics(Future Technologies)Nanjing Tech University(Nanjing Tech)Nanjing 211816China

A thermo-responsive rewritable plasmonic bio-memory chip has been successfully fabricated on an indium tin oxide(ITO)glass slide by assembling core-satellite gold nanoclusters with different size of gold nanoparticles(AuNPs)using double-strand DNA(dsDNA)*** the prepared 70@DNA20@13 gold nanoclusters(AuNCs)exhibited more stable and greater photothermal conversion *** short time irradiation by 633 nm microbeam laser,every individual AuNCs could be excited and remove the satellite AuNPs on its ***,in the dissociation process of AuNCs with 3−5 satellite,its color would change from yellow to green,which showed more significant reduction in the red channel of the dark-field microscopy(DFM)images and could be defined to state“0”and“1”***,this plasmonic nano bio-memory could transform cyclically its state between 0 and 1 which exhibited excellent rewritable ability.

关键词： plasmonic assembly thermal-responsive single nanoparticle rewritable bio-memory

Caring for Those In Special Need

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Women of China 1998年第5期 48-49页

作者： HUANG xiaomei FAN yi

Millions of men and women in the world are living in a miserable abyss. They can hear sounds that others don’t, see images that others cannot, and their minds are filled with eccentric ideas. Even as they smile, misery is gnawing at the heart; they may sit quietly, but it feels like hundreds of horses are stampeding inside their brains. They are overwhelmed by worry and fear. In this way, the serious person becomes silly, the energetic goes dull, the cheerful turns gloomy and the honest may cheat *** other words, they have been plunged into uncontrollable fantasies that take them far away from reality. They are the mentally ill, and they are deeply unfortunate." Professor Xia Zhenyi, a well-known Chinese psychiatrist, offered this sympathetic view of his patients. He reminds us: "Mental patients are human beings too.

关键词： In Ni Caring for Those In Special Need

Research progress on the role of extracellular vesicles in neurodegenerative diseases

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Translational Neurodegeneration 2023年第1期12卷 296-314页

作者： Zhengzhe Li Xiaoling Wang Xiaoxing Wang xiaomei yi yin Kwan Wong Jiyang Wu Fangfang Xie Die Hu Qi Wang Jigang Wang Tianyu Zhong The First School of Clinical Medicine Gannan Medical UniversityGanzhou 341000China Laboratory Medicine First Affiliated Hospital of Gannan Medical UniversityGanzhou 341000China Department of Nephrology Shenzhen Key Laboratory of Kidney Diseasesand Shenzhen Clinical Research Centre for GeriatricsShenzhen People’s HospitalThe First Affiliated HospitalSouthern University of Science and TechnologyShenzhen 518020China State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs Artemisinin Research Centerand Institute of Chinese Materia MedicaChina Academy of Chinese Medical SciencesBeijing 100700China Department of Oncology The Affiliated Hospital of Southwest Medical UniversityLuzhou 646000China

Neurodegenerative diseases,such as Alzheimer’s disease,Parkinson’s disease,amyotrophic lateral sclerosis,and Huntington’s disease,affect millions of people *** efforts have been put into disease-related research,but few breakthroughs have been made in diagnostic and therapeutic *** vesicles(EVs)are heterogeneous cell-derived membrane structures that arise from the endosomal system or are directly separated from the plasma *** contain many biomolecules,including proteins,nucleic acids,and lipids,which can be transferred between different cells,tissues,or organs,thereby regulating cross-organ communication between cells during normal and pathological ***,EVs have been shown to participate in various aspects of neurodegenerative *** secretion and levels of EVs are closely related to the pathogenesis of neurodegenerative diseases and contribute to disease *** studies have proposed EVs as therapeutic targets or biomarkers for neurodegenerative *** this review,we summarize and discuss the advanced research progress on EVs in the pathological processes of several neurodegenerative ***,we outline the latest research on the roles of EVs in neurodegenerative diseases and their therapeutic potential for the diseases.

关键词： Extracellular vesicle Neurodegenerative disease Central nervous system Neurodegeneration Pathogenesis Biomarker

Design Principles and Mechanistic Understandings of Non-Noble-Metal Bifunctional Electrocatalysts for Zinc-Air Batteries

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Nano-Micro Letters 2024年第9期16卷 13-48页

作者： Yunnan Gao Ling Liu yi Jiang Dexin Yu xiaomei Zheng Jiayi Wang Jingwei Liu Dan Luo Yongguang Zhang Zhenjia Shi Xin Wang Ya‑Ping Deng Zhongwei Chen Power Battery and Systems Research Center State Key Laboratory of CatalysisDalian Institute of Chemical PhysicsDalian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023People’s Republic of China Department of Chemical Engineering University of WaterlooWaterlooON N2L 3G1Canada Institute of Carbon Neutrality Zhejiang Wanli UniversityNingbo 315100People’s Republic of China College of Materials and Chemistry China Jiliang UniversityHangzhou 310018People’s Republic of China

Zinc-air batteries(ZABs)are promising energy storage systems because of high theoretical energy density,safety,low cost,and abundance of ***,the slow multi-step reaction of oxygen and heavy reliance on noble-metal catalysts hinder the practical applications of ***,feasible and advanced non-noble-metal elec-trocatalysts for air cathodes need to be identified to promote the oxygen catalytic *** this review,we initially introduced the advancement of ZABs in the past two decades and provided an overview of key developments in this ***,we discussed the work-ing mechanism and the design of bifunctional electrocatalysts from the perspective of morphology design,crystal structure tuning,interface strategy,and atomic *** also included theoretical studies,machine learning,and advanced characterization technologies to provide a comprehensive understanding of the structure-performance relationship of electrocatalysts and the reaction pathways of the oxygen redox ***,we discussed the challenges and prospects related to designing advanced non-noble-metal bifunctional electrocatalysts for ZABs.

关键词： Zinc-air batteries Bifunctional electrocatalysts Design principles Mechanistic understandings

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集值Rough扩展模型知识约简

计算机工程与应用 2011年第31期47卷 138-140,150页

作者：吴鹏易晓梅浙江农林大学信息工程学院浙江临安311300

基于吴鹏等提出的k度限制相容关系模型,讨论在集值不完备信息系统上的约简,给出集值不完备信息系统属性约简的判定定理和辨识矩阵,得到集值不完备信息系统知识约简的具体操作方法。

关键词： Rough集集值信息系统限制相容关系知识约简

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基于虚拟力的能耗均衡层次路由协议

传感技术学报 2018年第2期31卷 271-275页

作者：金鑫易晓梅吴鹏浙江农林大学信息工程学院浙江临安311300

大规模无线传感器网络路由转发中主要存在节点负载不均衡,容易导致"热区"中节点过早死亡,从而大大降低传感器网络生存时间的问题。针对这一问题,本文提出一种新的路由协议ECFP,首先利用节点与Sink节点的最短跳数建立簇首竞争半径,根据... 详细信息

大规模无线传感器网络路由转发中主要存在节点负载不均衡,容易导致"热区"中节点过早死亡,从而大大降低传感器网络生存时间的问题。针对这一问题,本文提出一种新的路由协议ECFP,首先利用节点与Sink节点的最短跳数建立簇首竞争半径,根据簇首竞争半径选择剩余能量较高、链路质量较好的节点出任簇首,然后基于虚拟力模型进行非均匀分簇,最后簇首之间多跳将信息传输至Sink节点。实验结果表明本文提出的协议在能耗均衡性和网络生存时间方面都具有较好的性能。

关键词：无线传感器网络能耗均衡非均匀分簇虚拟力

How can we establish animal models of HIV-associated lymphoma?

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Animal Models and Experimental Medicine 2024年第4期7卷 484-496页

作者： Qing Xiao Liuyue Zhai xiaomei Zhang yi Liu Jun Li Xiaoqing Xie Guofa Xu Sanxiu He Huihui Fu yifeng Tang Fujie Zhang Yao Liu Chongqing Key Laboratory of Translational Research for Cancer Metastasis and Individualized Treatment Department of Hematology-OncologyChongqing University Cancer HospitalChongqingChina Beijing Ditan Hospital Capital Medical UniversityBeijingChina

Human immunodeficiency virus(HIV)infection is strongly associated with a height-ened incidence of *** mirror the natural course of human HIV infection,animal models have been *** models serve as valuable tools to inves-tigate disease pathobiology,assess antiretroviral and immunomodulatory drugs,ex-plore viral reservoirs,and develop eradication ***,there are currently no validated in vivo models of HIV-associated lymphoma(HAL),hampering progress in this crucial domain,and scant attention has been given to developing animal models dedicated to studying HAL,despite their pivotal role in advancing *** re-view provides a comprehensive overview of the existing animal models of HAL,which may enhance our understanding of the underlying pathogenesis and approaches for malignancies linked to HIV infection.

关键词： animal model HIV-associated lymphoma(HAL) human immunodeficiency virus(HIV) immunodeficient mice primate model