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Disentangling the factors that contribute to variation in forest biomass increments in the mid-subtropical forests of China

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Journal of Forestry Research 2016年第4期27卷 919-930页

作者： yin Ren Shanshan Chen xiaohua Wei Weimin Xi yunjian Luo Xiaodong Song Shudi Zuo yusheng y.ng Key Laboratory of Urban Environment and Health Key Laboratory of Urban Metabolism of Xiamen Institute of Urban Environment Chinese Academy of Sciences Ningbo Urban Environment Observation and Research Station-NUEORS Chinese Academy of Sciences Department of Earth and Environmental Sciences University of British Columbia Okanagan Campus Department of Biological and Health Sciences Texas A&M University-Kingsville College of Environment and Natural Resources Zhejiang University Key Laboratory of Humid Subtropical Eco-Geographical Processes Ministry of Education Fujian Normal University

Mid-subtropical forests are the main vegetation type of global terrestrial biomes, and are critical for maintaining the global carbon balance. However, estimates of forest biomass increment in mid-subtropical forests remain highly uncertain. It is critically important to determine the relative importance of different biotic and abiotic factors between plants and soil, particularly with respect to their influence on plant regrowth. Consequently,it is necessary to quantitatively characterize the dynamicspatiotemporal distribution of forest carbon sinks at a regional scale. This study used a large, long-term dataset in a boosted regression tree（BRT） model to determine the major components that quantitatively control forest biomass increments in a mid-subtropical forested region（Wuyishan National Nature Reserve, China）. Long-term,stand-level data were used to derive the forest biomass increment, with the BRT model being applied to quantify the relative contributions of various biotic and abiotic variables to forest biomass increment. Our data show that total biomass（t） increased from 4.62 9 106 to 5.30 9 106 t between 1988 and 2010, and that the mean biomass increased from 80.19 ± 0.39 t ha-1（mean ± standard error） to 94.33 ± 0.41 t ha-1in the study region. The major factors that controlled biomass（in decreasing order of importance） were the stand, topography, and soil. Stand density was initially the most important stand factor, while elevation was the most important topographic factor. Soil factors were important for forest biomass increment but have a much weaker influence compared to the other two controlling factors. These results provide baseline information about the practical utility of spatial interpolationmethods for mapping forest biomass increments at regional scales.

关键词： biomass forests subtropical stand abiotic Castanopsis increment quantitatively uncertain accounted

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妊娠早期和中期血维生素D与妊娠期糖尿病的关系探讨

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中国医药指南 2024年第9期22卷 62-65页

作者：陈美玉陈世荣陈伟环王笑华罗丽广东省广州市增城区妇幼保健医院妇产科广州511300

目的探究妊娠早期和中期血维生素D与妊娠期糖尿病的关系探讨。方法选取2022年2月1日至2023年5月31日期间于广州市增城区妇幼保健院产科门诊产检的单胎妊娠妇女,根据纳排标准共纳入500例,分别检测孕早期、孕中期血清25-(OH)D3浓度是否0.0... 详细信息

目的探究妊娠早期和中期血维生素D与妊娠期糖尿病的关系探讨。方法选取2022年2月1日至2023年5月31日期间于广州市增城区妇幼保健院产科门诊产检的单胎妊娠妇女,根据纳排标准共纳入500例,分别检测孕早期、孕中期血清25-(OH)D3浓度是否ng/ml,诊断为缺乏和不缺乏。根据OGTT试验结果将受检孕妇分为GDM组(40例)和健康组(460例)。比较两组不同孕期25-(OH)D3水平、孕中期25-(OH)D3水平,比较GDM的单因素分析以及GDM的多因素Logistic回归分析。结果两组孕早期25-(OH)D3缺乏、不缺乏占比对比差异无统计学意义(P>0.05),两组孕中期的25-(OH)D3缺乏、不缺乏占比对比差异有统计学意义(P0.05),糖尿病家族史、25-(OH)D3、TG、HDL-C对比差异有统计学意义(P<0.05);经Logistic回归分析结果显示,糖尿病家族史、25-(OH)D3、TG、HDL-C是影响GDM的危险因素(P<0.05)。结论孕妇血清25-(OH)D3缺乏是GDM发病的高危因素。因此,合理补充维生素D可能有助于预防孕妇维生素D缺乏,并降低妊娠期糖尿病的风险。

关键词：妊娠期糖尿病妊娠早期妊娠中期 25-羟维生素D3 关系探讨

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帕博利珠单抗联合白蛋白紫杉醇与卡培他滨方案治疗进展期胃癌患者的疗效评估

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国际医药卫生导报 2024年第9期30卷 1430-1434页

作者：王文斌郭小花郑兆华郭曼孙力西安交通大学附属红会医院消化外科西安710001

目的探讨帕博利珠单抗联合白蛋白紫杉醇与卡培他滨方案在治疗进展期胃癌中的疗效。方法选取2019年10月至2022年9月西安交通大学附属红会医院收治的122例进展期胃癌患者进行随机对照试验,按照随机数字表法分为两组,各61例。对照组男48例... 详细信息

目的探讨帕博利珠单抗联合白蛋白紫杉醇与卡培他滨方案在治疗进展期胃癌中的疗效。方法选取2019年10月至2022年9月西安交通大学附属红会医院收治的122例进展期胃癌患者进行随机对照试验,按照随机数字表法分为两组,各61例。对照组男48例、女13例,年龄(62.45±5.47)岁,接受卡培他滨方案联合白蛋白紫杉醇治疗;观察组男47例、女14例,年龄(63.14±5.65)岁,在对照组基础上增加帕博利珠单抗治疗。每3周为1个疗程,治疗2个疗程。对比两组患者临床疗效、治疗前后血清肿瘤标志物[糖类抗原724(CA-724)、糖类抗原199(CA-199)、血管内皮生长因子(VEGF)、肿瘤坏死因子-α(TNF-α)]、不良反应及预后情况。采用t检验、χ^(2)检验。结果观察组总有效率为68.85%(42/61),高于对照组的47.54%(29/61),差异有统计学意义(χ^(2)=5.509,P=0.019)。治疗前,两组患者CA-724、CA-199、VEGF、TNF-α水平比较,差异均无统计学意义(均P>0.05);治疗6周后,观察组CA-724、CA-199、VEGF、TNF-α水平均低于对照组[(17.56±2.22)μg/L比(22.53±2.49)μg/L、(21.56±3.21)U/ml比(27.52±3.44)U/ml、(271.64±21.22)ng/L比(281.33±24.15)ng/L、(15.08±2.53)μg/L比(19.54±3.68)μg/L],差异均有统计学意义(t=11.636、9.893、2.354、7.800,均P0.05)。随访1年,观察组生存率为95.08%(58/61),高于对照组的83.61%(51/61),差异有统计学意义(χ^(2)=4.218,P=0.039)。结论帕博利珠单抗联合白蛋白紫杉醇治疗进展期胃癌的疗效良好,可有效降低血清肿瘤标志物水平。

关键词：进展期胃癌帕博利珠单抗白蛋白紫杉醇卡培他滨疗效血清肿瘤标志物

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Bonding-unsaturation-dependent superconductivity in P-rich sulfides

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Matter and Radiation at Extremes 2022年第4期7卷 81-88页

作者： Xing Li xiaohua Zhang y.ng Liu Guochun y.ng State Key Laboratory of Metastable Materials Science and Technology and Key Laboratory for Microstructural Material Physics of Hebei Province School of ScienceYanshan UniversityQinhuangdao 066004China Centre for Advanced Optoelectronic Functional Materials Research and Key Laboratory for UV Light-Emitting Materials and Technology of Northeast Normal University Changchun 130024China

The covalent frameworks found in certain compounds,such as the S–H skeleton in H3S and the H cage in LaH10,play an essential role in their *** compounds have the feature of bonding unsaturation(a deficiency of electrons in their covalent bonding)in *** an understanding of the relationship between superconductivity and bonding unsaturation in these materials can provide new ideas for the design of superconducting *** this work,we explored the high-pressure phase diagram of binary P–S compounds using first-principles swarm structural *** addition to the previously reported P2S and P3S structures,we identified that P5S,P8S,and P11S also have a common structural character of six-coordinated octahedral networks;however,their bonding unsaturation are distinct due to the different valence electron numbers and unequal ratios of P and S *** features provide an ideal model for exploring the bonding-unsaturation dependence of *** estimated the average bonding unsaturation of these P-rich compounds based on the valence electron numbers and the coordination numbers of the central P/S ***,the resultant average bonding unsaturation was found to be proportional to the predicted superconducting transition *** finding was also verified in MH9(M=y,Th,and Pr)and doped H3S(Si,C,and P)*** work provides an opportunity to gain a deeper understanding of bonding-unsaturation-dependent superconductivity.

关键词： saturation bonding superconductivity

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Nuclear Factor I/A Controls A-fiber Nociceptor Development

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Neuroscience Bulletin 2020年第7期36卷 685-695页

作者： Lu Qi Guangjuan yin y.ngchao Zhang yeqi Tao xiaohua Wu Richard M.Gronostajski Mengsheng Qiu y.ng Liu College of Life Sciences Zhejiang UniversityHangzhou 310058China Zhejiang Key Laboratory of Organ Development and Regeneration Institute of Life SciencesHangzhou Normal UniversityHangzhou 310036China Department of Biochemistry Program in GeneticsGenomics and BioinformaticsCenter of Excellence in Bioinformatics and Life SciencesState University of New York at BuffaloBuffaloNY 14203USA

Noxious mechanical information is transmitted through molecularly distinct nociceptors,with pinprickevoked sharp sensitivity via A-fiber nociceptors marked by developmental expression of the neuropeptide y receptor 2(Npy2 r)and von Frey filament-evoked punctate pressure information via unmyelinated C fiber nociceptors marked by ***,the molecular programs controlling their development are only beginning to be *** we demonstrate that Npy2 r-expressing sensory neurons are in fact divided into two groups,based on transient or persistent Npy2 r ***2 r-transient neurons are myelinated,likely including A-fiber nociceptors,whereas Npy2 r-persistent ones belong to unmyelinated pruriceptors that co-express *** then showed that the transcription factors NFIA and Runx1 are necessary for the development of Npy2 r-transient A-fiber nociceptors and MrgprD^+C-fiber nociceptors,***,mice with conditional knockout of Nfia,but not Runx1 showed a marked attenuation of pinprick-evoked nocifensive *** studies therefore identify a transcription factor controlling the development of myelinated nociceptors.

关键词： Dorsal root ganglion Acute pain Pinprick pain Npy2r Nppb Nociceptor A-fiber mechanonociceptor

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B-GQDs@GSH as a Highly Selective and Sensitive Fluorescent Probe for the Detection of Fe^(3+) in Water Samples and Intracellular

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Journal of Analysis and Testing 2023年第2期7卷 147-156页

作者： xiaohua y.ng Peigang Zhang Jie Tan Xuebing Li Weidong Zhang Wei Bian Martin M.F.Choi Department of Biochemistry and Molecular Biology School of Basic Medical ScienceShanxi Medical UniversityTaiyuan 030001China Lvliang People’s Hospital Lvliang 033000China Department of Traditional Chinese Medicine the First Hospital of Shanxi Medical UniversityTaiyuan 030001China

Owing to the excellent stability,biocompatibility and photoluminescence property,graphene quantum dots(GQDs)are emerging as a kind of potential materials to be applied in a series of fields ranging from sensor to drug *** the growing concern for human and environmental safety,selective detection of metal ions has been paid more and more ***,as nanoparticles with superior optical properties,have been attracting growing attention in the field of metal ions *** this work,glutathione(GSH)functionalized boron doped graphene quantum dots(B-GQDs@GSH)were successfully synthesized with stable bright blue fluorescence and has been used for the detection of Fe^(3+).A good linear relationship between 1/(F_(0)-F)and 1/c with the concentration ranging from 0.70 to 53μmol/L was obtained with a detection limit of 5.5 nmol/*** application of B-GQDs@GSH for Fe^(3+)detection in water samples was demonstrated and the quenching mechanism was further *** to low cytotoxicity and favorable biocompatibility,B-GQDs@GSH were successfully applied for cell fluorescence imaging and intracellular determination of Fe^(3+).

关键词： Fluorescence probe Quenching mechanism Real samples detection Intracellular detection

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Clinical observation of endoscopic skull base reconstruction with an anterolateral thigh free fascia flap

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Laparoscopic, Endoscopic and Robotic Surgery 2023年第2期6卷 73-77页

作者： Hong Pan Mang Xiao Jing ye Chen Qin xiaohua Jiang Department of Otorhinolaryngology Head&Neck Surgery Sir Run Run Shaw HospitalZhejiang University School of MedicineHangzhou 310016China

Objective:Radiation osteonecrosis of the skull base after radiotherapy for nasopharyngeal carcinoma is one of the most serious complications,affecting patient survival and quality of *** date,surgical resection is the main treatment for radiation *** repair after the operation is very *** repair or lack of repair can easily cause local infection that can even spread to the brain,aggravating *** study aimed to verify the feasibility and safety of the ante-rolateral thigh free fascia flap in repairing large skull base ***:From June 2021 to July 2022,a total of 12 patients with a history of radiotherapy for naso-pharyngeal carcinoma received surgical treatment at the Department of Otolaryngology Head&Neck Surgery,Sir Run Run Shaw Hospital,Zhejiang University School of *** patients were diagnosed with radiation osteonecrosis of the skull base with large skull base *** the endoscopic operation,a free anterolateral thigh fascia flap was used to repair the skull base and complete vascular anastomosis *** preoperative and postoperative pain scores were retrospectively analyzed,and the dynamic changes in endoscopic surgery sites were ***:The 12 patients had a median age of 58 y,with 8(66.7%)males and 4(33.3%)*** median headache score for the patients was 5(4-7)before *** patient's headache was significantly relieved postoperatively,with 11 patients having a score of 0 and one patient having a score of *** stench was completely resolved after the *** were no serious complications during the perioperative period or 12 months after the ***:The application of anterolateral thigh free fascia flap in skull base reconstruction is a safe and reliable reconstruction technique suitable for endoscopic surgical repair of large-scale skull base necrosis.

关键词： Radiation osteonecrosis Skull base reconstruction Anterolateral thigh free fascia flap Endoscopic

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应用C-to-G碱基编辑器对PCSK9基因靶向敲除的研究

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中国计划生育学杂志 2024年第6期32卷 1231-1235,1464页

作者：刘惠聪曹小芳万子睿安莉莎金孝华马旭国家卫生健康委科学技术研究所北京100081 北京协和医学院研究生院首都医科大学附属北京朝阳医院

目的:使用C-to-G碱基编辑器(CGBE)Td-CGBE-ng靶向敲除huh-7肝癌细胞系前蛋白转化酶枯草溶菌素9(PCSK9)基因,以CBE(AncBE4max)为参照,评价Td-CGBE-ng对该基因的敲除效果。方法:使用引入终止密码子的策略敲除huh-7肝癌细胞系PCSK9基因。... 详细信息

目的:使用C-to-G碱基编辑器(CGBE)Td-CGBE-ng靶向敲除huh-7肝癌细胞系前蛋白转化酶枯草溶菌素9(PCSK9)基因,以CBE(AncBE4max)为参照,评价Td-CGBE-ng对该基因的敲除效果。方法:使用引入终止密码子的策略敲除huh-7肝癌细胞系PCSK9基因。构建碱基编辑器Td-CGBE-ng和AncBE4max,构建重组质粒sg386和sg555,将Td-CGBE-ng和sg386,AncBE4max和sg555分别共转染huh-7细胞,实现c.1447C>G和c.1953C>T的转换,在两位点引入终止密码子S386X(TGA)和Q555X(TAG),使用sanger测序和T载体克隆验证编辑效率;实时荧光定量聚合酶链反应(RT-qPCR)和蛋白免疫印迹法(Western blot)检测PCSK9基因mRNA和蛋白表达水平的变化。结果:sanger测序和T载体克隆结果显示,Td-CGBE-ng和AncBE4max的编辑效率分别为c.1447C>G 33%和c.1953C>T 25%;RT-qPCR结果显示,Td-CGBE-ng使PCSK9 mRNA的表达量降低(t=17.29,Png:t=4.912,Png可以有效敲除huh-7肝癌细胞系的PCSK9基因,抑制该基因mRNA和蛋白的表达,为后续Td-CGBE-ng的应用奠定基础。

关键词：前蛋白转化酶枯草溶菌素9(PCSK9) CRISPR/Cas 碱基编辑 huh-7肝癌细胞系

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肿瘤专科医院临床护士疼痛共情现状及影响因素

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护理研究 2024年第2期38卷 344-348页

作者：董勇关琼瑶蔡帅中任晓华杨海银杨诗瑶颜芳王成娟云南省肿瘤医院(昆明医科大学第三附属医院) 云南650118 昆明市延安医院

目的:了解肿瘤专科医院临床护士的疼痛共情现状并对其影响因素进行分析。方法:便利抽取2023年2月1日—3月1日云南省、贵州省、四川省、广西壮族自治区5所肿瘤专科医院的953名临床护士作为研究对象。采用一般资料调查表、疼痛共情量表、... 详细信息

目的:了解肿瘤专科医院临床护士的疼痛共情现状并对其影响因素进行分析。方法:便利抽取2023年2月1日—3月1日云南省、贵州省、四川省、广西壮族自治区5所肿瘤专科医院的953名临床护士作为研究对象。采用一般资料调查表、疼痛共情量表、心理弹性量表进行调查。结果:肿瘤专科医院临床护士疼痛共情总分为(2.73±0.75)分,心理弹性、性别、婚姻状况、科室、有无宗教信仰、是否接触过疼痛共情相关的培训、是否经历过较大创伤引起的疼痛是肿瘤专科医院临床护士疼痛共情能力的影响因素,共解释总变异的9.7%。结论:肿瘤专科医院临床护士疼痛共情能力处于中等水平,护理管理者应根据临床护士的疼痛共情能力影响因素,加大临床护士的心理弹性建设,缓解护士临床工作中的同情疲劳,探究长期、有效的共情能力培养与提升策略,提高临床护士的疼痛共情能力。

关键词：肿瘤医院护士疼痛共情影响因素护理管理

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Analgesic effect of acupuncture at Hegu (LI 4) on transvaginal oocyte retrieval with ultrasonography

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Journal of Traditional Chinese Medicine 2013年第3期33卷 294-297页

作者： Jianwei Zhang xiaohua Wang Ruisha Lü Reproduction and Heredity Center Combining Traditional Chinese Medicine with Western Medicine in Hospital Affiliated to Shandong University of Traditional Chinese Medicine Shandong University of Traditional Chinese Medicine Master Degree Candidate of 2006 Grade in Shandong University of Traditional Chinese Medicine

OBJECTIVE: To observe the analgesic effect of acupuncture at Hegu (LI 4) in vitro fertilization-embryo transfer (IVF-ET) transvaginal oocyte retrieval using ultrasonography and explore its mechanism. METHODS: Ninety patients undergoing IVF-EF oocyte retrieval were randomly divided into three groups: an acupuncture group with needles inserted into bilateral Hegu (LI 4) points, a placebo group given placebo needles, and a control group with routine oocyte retrieval. Each group had an indometacin enema 30 min before the operation. We compared the pain-rated index (PRI), visual analogy scale (VAS), and present pain intensity (PPI) immediately after operation and 1 h after operation. We also determined the neuropeptide y (NPy) level of the follicular fluid. RESULTS: PRI, VAS, and PPI after operation and 1 hafter operation in the acupuncture group were significantly lower than those in the control group (P0.05) was observed in PRI,VAS, and PPI after operation and 1 h after operation between the placebo group and the control *** NPy level of the follicular fluid in the acupuncture group was significantly higher than that in the control group (P0.05) was observed in the NPy level of the follicular fluid between the placebo group and the control group. CONCLUSION: The analgesic effect of acupuncture at Hegu in transvaginal oocyte retrieval using ultrasonography may be related to the increase in the NPy level of the follicular fluid.

关键词： Acupuncture Hegu (LI 4) Analgesics,non-narcotic Oocyte retrieval Neuropeptide y

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