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Triboelectric nanogenerators for self-powered neurostimulation

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Nano Research 2024年第10期17卷 8926-8941页

作者： Shumao Xu Farid Manshaii xiao.xiao.junyi yin Jun Chen Department of Bioengineering University of CaliforniaLos AngelesLos AngelesCA 90095USA

The burgeoning field of soft bioelectronics heralds a new dawn in medical treatment for neurological and psychiatric conditions,presenting innovative methods for the stimulation,inhibition,and precise sensing of neuronal *** to these advancements is the challenge of power supply;devices dependent on traditional batteries face limitations regarding miniaturization and require invasive surgeries for battery *** nanogenerators(TENGs),which generate power from biomechanical movements,offer a promising solution for developing self-powered neurostimulation devices without the need for an external power *** review delves into recent progress in TENGs,with a focus on their application in selfpowered neurostimulation *** utility of TENGs across various nervous systems—including the center,autonomic,and somatic nervous systems—is explored and presented,highlighting the potential for these devices to facilitate neurological *** summarizing TENGs’operational details and the potential for clinical translation,this review also identifies challenges associated with the implantation and integration of neural electrodes and presents recent advances in solutions,aiming to reshape electric treatments for neurological diseases.

关键词： triboelectric nanogenerators neurostimulation self-powered soft bioelectronics biomechanical energy harvesting

Service Function Chain Migration in LEO Satellite Networks

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China Communications 2024年第3期21卷 247-259页

作者： Geng Yuhui Wang Niwei Chen Xi Xu xiaofan Zhou Changsheng Yang junyi xiao Zhenyu Cao Xianbin School of Electronic and Information Engineering Beihang UniversityBeijing 100191China Key Laboratory of Advanced Technology of Near Space Information System Ministry of Industry and Information Technology of ChinaBeijing 100191China Shanghai Key Laboratory of Satellite Network Shanghai 201204China Shanghai Satellite Network Research Institute Co. Ltd.Shanghai 201204China

With the advancements of software defined network(SDN)and network function virtualization(NFV),service function chain(SFC)placement becomes a crucial enabler for flexible resource scheduling in low earth orbit(LEO)satellite *** due to the scarcity of bandwidth resources and dynamic topology of LEO satellites,the static SFC placement schemes may cause performance degradation,resource waste and even service *** this paper,we consider migration and establish an online migration model,especially considering the dynamic *** the scarcity of bandwidth resources,the model aims to maximize the total number of accepted SFCs while incurring as little bandwidth cost of SFC transmission and migration as *** to its NP-hardness,we propose a heuristic minimized dynamic SFC migration(MDSM)algorithm that only triggers the migration procedure when new SFCs are *** results demonstrate that MDSM achieves a performance close to the upper bound with lower complexity.

关键词： network function virtualization(NFV) resource allocation satellite networks service function chain(SFC) SFC migration SFC placement soft-ware defined network(SDN)

Gut microbial metabolite targets HDAC3-FOXK1-interferon axis in fibroblast-like synoviocytes to ameliorate rheumatoid arthritis

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Bone Research 2024年第2期12卷 421-437页

作者： Hongzhen Chen Xuekun Fu xiaohao Wu junyi Zhao Fang Qiu Zhenghong Wang Zhuqian Wang Xinxin Chen Duoli Xie Jie Huang Junyu Fan Xu Yang Yi Song Jie Li Dongyi He Guozhi xiao Aiping Lu Chao Liang Department of Systems Biology School of Life SciencesSouthern University of Science and TechnologyGuangdong Provincial Key Laboratory of Cell Microenvironment and Disease ResearchShenzhen Key Laboratory of Cell MicroenvironmentShenzhen 518055China Institute of Integrated Bioinfomedicine and Translational Science(IBTS) School of Chinese MedicineHong Kong Baptist UniversityHong Kong SAR 999077China Department of Biochemistry School of MedicineSouthern University of Science and TechnologyGuangdong Provincial Key Laboratory of Cell Microenvironment and Disease ResearchShenzhen Key Laboratory of Cell MicroenvironmentShenzhen 518055China Division of Immunology and Rheumatology Stanford UniversityStanfordCA 94305USA VA Palo Alto Health Care System Palo AltoCA 94304USA Institute of Plant and Food Science Department of BiologySouthern University of Science and TechnologyShenzhen 518055China Department of Rheumatology Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese MedicineShanghai University of Traditional Chinese MedicineShanghaiChina Department of Computational Biology St.Jude Children’s Research HospitalMemphisTNUSA Department of Laboratory Medicine Peking University Shenzhen HospitalShenzhenChina Guangdong-Hong Kong-Macao Joint Lab on Chinese Medicine and Immune Disease Research Guangzhou 510006China Shanghai University of Traditional Chinese Medicine Shanghai 200032China State Key Laboratory of Proteomics National Center for Protein Sciences(Beijing)Beijing Institute of Lifeomics100850 BeijingChina

Rheumatoid arthritis(RA)is an autoimmune *** studies hold an opinion that gut microbiota is environmentally acquired and associated with RA ***,accumulating evidence demonstrates that genetics also shape the gut *** is known that some strains of inbred laboratory mice are highly susceptible to collagen-induced arthritis(CIA),while the others are resistant to ***,we show that transplantation of fecal microbiota of CIA-resistant C57BL/6J mice to CIA-susceptible DBA/1J mice confer CIA resistance in DBA/1J mice.C57BL/6J mice and healthy human individuals have enriched *** than DBA/1J mice and RA *** of *** prevents CIA in DBA/1J *** identify that *** mainly produces propionate and C57BL/6J mice and healthy human individuals have higher level of ***-like synoviocytes(FLSs)in RA are activated to undergo tumor-like *** disrupts HDAC3-FOXK1 interaction to increase acetylation of FOXK1,resulting in reduced FOXK1 stability,blocked interferon signaling and deactivation of *** treat CIA mice with propionate and show that propionate attenuates ***,a combination of propionate with anti-TNF etanercept synergistically relieves *** results suggest that *** or propionate could be an alternative or complementary approach to the current therapies.

关键词： HDAC3 cytes interferon

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基于最佳采样点的GMSK相干接收算法

系统工程与电子技术 2024年第9期46卷 3239-3245页

作者：孙岩博杜俊逸肖磊李根中国电子科技集团公司第十研究所四川成都610036 电子科技大学自动化工程学院四川成都611731

针对高斯滤波最小频移键控(Gaussian-filtered minimum shift keying,GMSK)相位连续性导致相位估计存在模糊度问题,提出一种基于最佳采样点的GMSK相干接收算法。发射端通过构造预编码方式对原始消息编码后调制,以实现符号间的相位解耦,... 详细信息

针对高斯滤波最小频移键控(Gaussian-filtered minimum shift keying,GMSK)相位连续性导致相位估计存在模糊度问题,提出一种基于最佳采样点的GMSK相干接收算法。发射端通过构造预编码方式对原始消息编码后调制,以实现符号间的相位解耦,接收端在码间串扰最小时刻实现最佳采样点抽取,将GMSK转变成类偏移四相相移键控(offset quadrature phase shift keying,OQPSK)调制,有效避免未知数据段对后续同步段引入模糊初相而导致多普勒相位和频率无法准确估计的问题,最后提出基于最佳采样点的GMSK相干解调算法,实现低复杂度的可靠接收。仿真结果表明,所提算法多普勒频率估计范围大且估计精度高,同时与最佳解调接收机相比,所提算法解调复杂度低且解调性能损失小。

关键词：高斯滤波最小频移键控最佳采样多普勒相位估计相干解调

复合亚固溶热处理对一种新型镍基粉末高温合金涡轮盘锻态显微组织的影响

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稀有金属材料与工程 2024年第3期53卷 768-777页

作者：刘朝峰程俊义马向东肖磊郭建政冯干江中南大学粉末冶金国家重点实验室湖南长沙410083 深圳市万泽中南研究院有限公司广东深圳518035

研究了复合亚固溶热处理工艺对一种新型镍基粉末高温合金FGH4113A(WZ-A3)γ’相组织的影响。结果表明,大尺寸锻造态涡轮盘件锻后冷速较低,γ’相的尺寸在100~4500 nm之间分布。在盘件上取小试样进行热处理试验,试样升温至1000和1050℃时... 详细信息

研究了复合亚固溶热处理工艺对一种新型镍基粉末高温合金FGH4113A(WZ-A3)γ’相组织的影响。结果表明,大尺寸锻造态涡轮盘件锻后冷速较低,γ’相的尺寸在100~4500 nm之间分布。在盘件上取小试样进行热处理试验,试样升温至1000和1050℃时,γ’相总占比下降,Oswald熟化机制及PAM机制同时存在。试样升温至1100℃时,晶内γ’相完全回溶。使用复合亚固溶热处理工艺,先将试样升温至1120℃保温2 h,快速冷却后再分别升温至1000、1050和1100℃时,γ’相总占比均下降,晶内γ’相演变以Oswald熟化机制为主导,其形貌及尺寸在升温过程中相对稳定。在盘件上取性能试棒分别进行锻造态+1000℃(不保温)+时效热处理和锻造态+1120℃/2h,80℃/min+1000℃+815℃/8h进行550℃拉伸测试,后者的屈服强度和抗拉强度显著高于前者,可为大尺寸涡轮盘件的双性能热处理工艺的制定提供参考。

关键词：镍基粉末高温合金热处理显微组织 γ’相

“6.1”芦山地震作用下宝兴新华村滑坡动力响应与失稳过程离散元模拟

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地质科技通报 2024年第2期43卷 226-237页

作者：周赞罗永红南凯李均益马潇成都理工大学环境与土木工程学院成都610059 成都理工大学地质灾害防治与地质环境保护国家重点实验室成都610059

斜坡浅表层是各类地震地质灾害发育的潜在破坏位置,坡面形态和坡体结构往往造成斜坡动力响应及破坏的复杂化。为探究不稳定斜坡浅表潜在滑动层动力响应特征与失稳过程,以芦山M_(s)6.1级地震触发的新华村滑坡为例,基于现场调查采用离散... 详细信息

斜坡浅表层是各类地震地质灾害发育的潜在破坏位置,坡面形态和坡体结构往往造成斜坡动力响应及破坏的复杂化。为探究不稳定斜坡浅表潜在滑动层动力响应特征与失稳过程,以芦山M_(s)6.1级地震触发的新华村滑坡为例,基于现场调查采用离散元方法建立了二维计算模型,分析了该斜坡潜在滑动层及坡面形态的动力响应特征并对其失稳过程进行了模拟。结果表明:(1)斜坡浅表潜在滑动层具有强烈动力放大效应;(2)微地貌对于潜在不稳定斜坡坡面的放大效应具有明显的影响,浅表潜在滑动层水平向及竖直向加速度在凸出部位的放大效应显著,凹陷部位相较于凸出部位放大效应较低;(3)研究揭示新华村滑坡在微地貌的作用下凸起地形呈现先于凹陷地形遭受破坏,其失稳过程分为震动放大局部震裂-凸出地形破坏-凹陷地形破坏-完全破坏整体下滑-重力堆积5个阶段。该研究结果有助于提升防灾人员对地震诱发潜在不稳定斜坡失稳的认识,为防灾减灾提供理论和数据支撑。

关键词：芦山M_(s)6.1级地震地震滑坡动力响应变形破坏模型二维离散元模拟新华村滑坡

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数字经济与以人民为中心的发展

西藏发展论坛 2024年第1期 40-44页

作者：肖鲁伟史珺怡西藏民族大学财经学院上海建设管理职业技术学院智慧城市管理学院

中国共产党区别于其他一切政党的根本标志是全心全意为人民服务。中国共产党领导下的经济社会发展是以人民为中心的发展。更有为政府与更有效市场是中国共产党创造的践行以人民为中心发展理念的两只重要抓手。数字技术的发展为更有为政... 详细信息

中国共产党区别于其他一切政党的根本标志是全心全意为人民服务。中国共产党领导下的经济社会发展是以人民为中心的发展。更有为政府与更有效市场是中国共产党创造的践行以人民为中心发展理念的两只重要抓手。数字技术的发展为更有为政府和更有效市场提供了新的重要技术支撑。本文从上述视角提出了西藏数字经济发展的相应对策。

关键词：西藏数字经济更有为政府更有效市场以人民为中心

一种新型镍基粉末高温合金涡轮盘的双性能热处理工艺研究

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稀有金属材料与工程 2024年第9期53卷 2614-2623页

作者：程俊义刘朝峰马向东肖磊郭建政冯干江中南大学粉末冶金国家重点实验室湖南长沙410083 深圳市万泽中南研究院有限公司广东深圳518035

采用真空感应熔炼+制粉+热等静压+热挤压+等温锻工艺制备实验盘坯,在实验盘坯上取样并进行热处理和力学性能测试,得到合金FGH4113A的亚固溶和过固溶热处理温度范围和力学性能变化规律。同时,通过测温实验验证仿真模拟的热边界条件。随后... 详细信息

采用真空感应熔炼+制粉+热等静压+热挤压+等温锻工艺制备实验盘坯,在实验盘坯上取样并进行热处理和力学性能测试,得到合金FGH4113A的亚固溶和过固溶热处理温度范围和力学性能变化规律。同时,通过测温实验验证仿真模拟的热边界条件。随后,提出了一种基于实验和有限元分析方法设计盘轴一体化镍基粉末高温合金涡轮盘的热处理工艺方法。最后,采用该方法制定的热处理工艺,成功地制备出了大尺寸双性能涡轮盘,并对其不同部位的显微组织和力学性能进行系统的验证和分析。结果表明:采用该方法制备的全尺寸双性能盘件不同部位的晶粒尺寸符合预测;通过改变隔热工装的尺寸和热处理保温时间可以调整盘件热处理的温度梯度;盘件晶粒过渡区晶粒尺寸过渡平缓;细晶组织的合金具有较好的低温强度,而粗晶组织的合金则具有较好的高温抗蠕变性能。

关键词：镍基粉末高温合金双性能热处理显微组织有限元分析

Adsorption of fluoride on clay minerals and their mechanisms using X-ray photoelectron spectroscopy

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Frontiers of Environmental Science & Engineering 2011年第2期5卷 212-226页

作者： junyi DU Daishe WU Huayun xiao Ping LI Department of Environmental Science and Engineering Nanchang UniversityNanchang 330031China

This research investigates the adsorptionmechanisms of fluoride(F)on four clay minerals(kaolinite,montmorillonite,chlorite,and illite)underdifferent F^(-)concentrations and reaction times by probingtheir fluoride superficial layer binding energies and elementcompositions using X-ray photoelectron spectroscopy(XPS).At high F^(-)concentrations(C_(0)=5-1000 mg·L^(-1)),the amount of F^(-)adsorbed(Q_(F)),amount of hydroxidereleased by clay minerals,solution F^(-)concentration,andthe pH increase with increasing C_(0).The increases areremarkable at C_(0)>50 mg·L^(-1).The QF increases significantlyby continuously modifying the pH *** C_(0)100 mg·L^(-1),newminerals precipitate and the product depends on the criticalAl^(3+)***[Al^(3+)]>10^(-11.94)mol·L^(-1),cryoliteforms,while at[Al^(3+)]<10^(-11.94)mol·L^(-1),AlF_(3) is *** low C_(0)(0.3-1.5 mg·L^(-1)),proton transfer occurs,andthe F^(-)adsorption capabilities of the clay minerals increasewith time.

关键词： clay mineral fluoride(F) adsorption mechanism X-ray photoelectron spectroscopy(XPS)