检索结果-南通市图书馆

血液透析联合血液灌流治疗中抗凝剂的合理运用

在线全文

学校读者我要写书评

暂无评论

中国医药指南 2013年第20期11卷 20-21页

作者：陈启光周俊肖义佳王颖黄朝莲成都市九星医院血透室四川成都610041

目的准确掌握抗凝剂的使用量。方法 23例慢性维持性血液透析患者入选本研究,随机分为对照组和实验组,在ACT监测下使用肝素抗凝,观察患者出凝血情况,及个体肝素使用剂量。结果 ACT监测下抗凝剂量差异大,抗凝时间目标值得到新的定位。结... 详细信息

目的准确掌握抗凝剂的使用量。方法 23例慢性维持性血液透析患者入选本研究,随机分为对照组和实验组,在ACT监测下使用肝素抗凝,观察患者出凝血情况,及个体肝素使用剂量。结果 ACT监测下抗凝剂量差异大,抗凝时间目标值得到新的定位。结论血液透析抗凝剂的运用需ACT目标值达170~250s为经验性的安全范围。血液灌流在本实验中证实安全范围在300~350s不凝血也不引起出血。至于个体之间同批次灌流器为何肝素消耗量有不同差异,是否与比表面积孔容相关还有待进一步探讨。

关键词： ACT监测抗凝血液透析联合血液灌流目标值

退役锂离子电池正极材料有价金属回收研究进展

在线全文

学校读者我要写书评

暂无评论

现代化工 2025年第1期45卷 66-71页

作者：李子庆董琪黄奕陶义杰张家驿王启黄淮学院能源工程学院河南驻马店463000

针对LiNi_(x)Co_(y)Mn_(1-x-y)O_(2)、LiFePO_(4)、LiMn_(2)O_(4)、LiCoO_(2)4大类锂离子电池正极材料中的目标金属的回收研究现状进行了详细阐述。首先是处理流程的难易程度直接关系到回收成本和效率;其次对不同回收工艺中目标金属的... 详细信息

针对LiNi_(x)Co_(y)Mn_(1-x-y)O_(2)、LiFePO_(4)、LiMn_(2)O_(4)、LiCoO_(2)4大类锂离子电池正极材料中的目标金属的回收研究现状进行了详细阐述。首先是处理流程的难易程度直接关系到回收成本和效率;其次对不同回收工艺中目标金属的提取以及对环境的影响等进行了全面分析;最后对比了不同回收工艺的优缺点,发现每种工艺都有其独特的适用场景和局限性。未来要实现退役锂离子电池的高效、环保处理,需要整合各种工艺的优点,创新回收技术。

关键词：锂离子电池正极材料有价金属回收

A review of non-noble metal-based electrocatalysts for CO_(2)electroreduction

在线全文

学校读者我要写书评

暂无评论

Rare Metals 2021年第11期40卷 3019-3037页

作者： jia-Jun Wang xiao-Peng Li Bing-Feng Cui Zhao Zhang xiao-Fei Hu jia Ding yi-Da Deng xiao-Peng Han Wen-Bin Hu School of Materials Science and Engineering Tianjin Key Laboratory of Composite and Functional MaterialsKey Laboratory of Advanced Ceramics and Processing Technology(Ministry of Education)Tianjin UniversityTianjin 300072China Thayer School of Engineering Dartmouth CollegeHanover NH 03755USA Joint School of National University of Singapore and Tianjin University International Campus of Tianjin UniversityFuzhou 350207China

The excessive emission of CO_(2) has caused many environmental issues and is severely threatening the ***_(2) electroreduction reaction(CO_(2) RR) that driven by sustainable power is an ideal route for realizing the net reduction of CO_(2) and carbon *** efficient electrocatalysts with low cost and high performance is critical for the wide applications of CO_(2) RR *** the various explored CO_(2) RR catalysts,non-noble metal(NNM)-based nanomaterials have drawn increasing attentions due to the remarkable performance and low *** this mini-review,the recent advances of NNM-based CO_(2) RR catalysts are summarized,and the catalysts are classified based on their corresponding reduction *** preparation strategies for engineering the electrocatalysts are introduced,and the relevant CO_(2) RR mechanisms are discussed in ***,the current challenges in CO_(2) RR research are presented,and some perspectives are proposed for the future development of CO_(2) RR *** mini-review introduces the recent advances and frontiers of NNM-based CO_(2) RR catalysts,which should shed light on the further exploration of efficient CO_(2) RR electrocatalysts.

关键词： CO_(2)electroreduction Non-noble metals Reaction mechanism Heterogeneous catalysis Structural-function relationship

Mechanism of water savings and pollution reduction in paddy fields of three typical areas in southern China

在线全文

学校读者我要写书评

暂无评论

International Journal of Agricultural and Biological Engineering 2022年第1期15卷 199-207页

作者： Menghua xiao Yuanyuan Li yi jia jianwen Wang Zhejiang Institute of Hydraulics and Estuary(Zhejiang Institute of Marine Planning and Design) Hangzhou 310020China North China University of Water Resource and Electric Power Zhengzhou 450045China Zhejiang Rural Water Conservancy Management Center Hangzhou 310009China Qiantang River Irrigation Area Management Center Xiaoshan DistrictHangzhou CityHangzhou 311200China

Field irrigation and drainage regulation and fertilization application could affect water utilization and pollution transportation in a paddy *** this study,representative rice-producing areas of Zhejiang Province in southern China were selected to study the effects of different field water level control(conventional irrigation and drainage W0,controlled irrigation and drainage W1 and W2)and different fertilization methods(2 times of fertilization F2 and three times of fertilization F3)on water irrigation quantity and consumption of rice,rice growth,water utilization,and pollution *** showed that field water level control had a great effect on irrigation quota in growing period rather than that in soaking period,and irrigation quota for W0 was 37.0%-71.7%higher than that for W1 and W2 in the whole growth period of *** the upper limit of rain storage was greatly increased by W1 and W2,on the contrary,the yield under W1 and W2 was 0.4%-2.1%higher than that under *** consumption,water leakage,and evapotranspiration were 16.63%-34.4%,39.97%-60.8%,and 9.40%-31.53%lower under W1 and W2 than those under W0,respectively,while it showed no significant changes under W1 and *** use rate and WUEI(water use efficiency of irrigation)under W1 and W2 had been significantly improved by 8.20%-129.58%and 31.58%-201.61%compared to *** contribution of nitrogen and phosphorus loss from surface water accounted for 90%and the total pollution load of total nitrogen(TN),NO_(3)^(-)-N,NH_(4)^(+)-N and chemical oxygen demand(COD)were 20.0%-63.4%,21.8%-66.3%,21.5%-63.8%,and 21.4%-46.5%lower for W1 and W2 than that for W0,***,compared to F2,dispersed fertilization(F3)was beneficial to increase the yield and decrease pollutant ***,the path of IRA→NH_(4)^(+)-N→COD and IRA→WCA→WUE_(I) presented partial remediation effect,and the effect size was 23.6%and 38.1%,respectively,the path of IRA→WUE_(I)→WUE_(ET) presented a full r

关键词： controlled irrigation and drainage water consumption water use efficiency non-point source pollution structural equation mode

Molecular characterization and gene functional analysis of Dicer-2 gene from Nilaparvata lugens （Hemiptera： Geometroidea）

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Insect Science 2013年第1期20卷 61-68页

作者： xiao-yi Zhang Kai Lu jia-Liang Zhou Qiang Zhou State Key Laboratory of Biological Control and Institute of Entomology Sun Yat-sen University Guangzhou China

Nilaparvata lugens （St^il）（Hemiptera： Geometroidea）, a serious rice pest in many countries of Asia, causes a great loss in rice production every year. RNA interference （RNAi） is a powerful technology for gene fimction study in insects and a potential tool for pest control. As a core component of RNAi pathway, Dicer-2 （Dcr-2） protein determines the production of small interfering RNA （siRNA） and is crucial for the efficiency of RNAi. In this study, the full-length complementary DNA （cDNA） ofN. lugens Dcr-2 （NlDcr-2） was first cloned and analyzed, and then the RNAi experiment was conducted to explore the function ofNlDcr-2 gene. The complete Dcv-2 cDNA ofN. lugens was 4 971 bp in length with an open reading frame （ORF） of 1,656 amino acids. Phylogenetic and protein domain analysis showed that the predicted N1Dcr-2 protein was similar to Tribolium castaneum. In the RNAi experiment, the messenger RNA level of NlDcr-2 was significantly reduced by NlDcr-2 double-stranded RNA （dsRNA）（dsDcr-2）. Fifty-five per cent decrease of N1Dcr-2 was found after 4 days of unremitting feeding. No significant effect was observed on the development ofN. lugens after dsRNA ingestion.

关键词： clone Dicer-2 Nilaparvata lugens RNAi qRT-PCR

Photoacoustic and Fluorescence Spectroscopy of Metallomesogens Containing Lanthanide Ions

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Chemical Physics 2008年第2期21卷 99-104页

作者： Yue-tao Yang Jun-jia Li xiao-jun Liu Shu-yi Zhang Jing Liu Key Laboratory of Modern Acoustics Ministry of Education Institute of Acoustics Nanjing University Nanjing 210093 China Beijing Synchrotron Radiation Facility Institute of High Energy Physics Chinese Academy of Sciences Beijing 100049 China

Metallomesogens Ln（bta）3L2 （Ln^3＋： La^3＋, Eu^3＋, and Ho^3＋; bta： benzoyltrifluoroacetonate; L： Schiff base） were prepared. Photoacoustic （PA） spectroscopy was used to study physicochemical properties of the liquid crystalline metal complexes. In the region of ligand absorption, PA intensity increases for Eu（bta）3L2, La（bta）3L2, and Ho（bta）3L2, in that order. It is found that the PA intensity of the ligand bears a relation to the intramolecular energy transfer process. For the first time, phase transitions of Eu（bta）3L2 from glass state to smectic A （SmA） phase and SmA phase to isotropic liquid are monitored by PA and fluorescence （FL） spectroscopy from two aspects： nonradiative and radiative transitions. The results show that PA technique may serve as a new tool for investigating the spectral properties and phase transitions of liquid crystals containing metal ions.

关键词： Photoacoustic spectroscopy Lanthanide complex Liquid crystal Relaxation process Phase transition

Selective and sensitive fluorescence imaging reveals microenvironment-dependent behavior of NO modulators in the endothelial system

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Pharmaceutical Analysis 2020年第5期10卷 466-472页

作者： ying Dong xiao-Rong Li jia Li yi Zang Xin Li College of Pharmaceutical Sciences Zhejiang UniversityHangzhou310058China State Key Laboratory of Drug Research Shanghai Institute of Materia MedicaChinese Academy of SciencesShanghai201203China University of Chinese Academy of Sciences Beijing100049China Open Studio for Draggability Research of Marine Natural Products Pilot National Laboratory for Marine Science and Technology(Qingdao)1 Wenhai RoadAoshanweiJimoQingdao266237China

Nitric oxide(NO)is a second messenger playing crucial roles in the signaling of a variety of cellular *** to its pathophysiological significance,various NO modulators have been developed to explore NO pathways and some have been used as *** modulators are often used directly to observe pharmacological effects in cell lines,but their actual effect on intracellular NO level is seldom ***,facilitated by a selective and sensitive fluorescence probe,we observed that some NO modulators displayed unexpected behaviors with both NO scavenger carboxy-PTIO and endothelial nitric oxide synthase(eNOS)inhibitor N(u)-nitro-L-arginine methyl ester(L-NAME)failing to decrease intracellular free NO level in ***926 cells while NO donor diethylamine-NONOate(DEA$NONOate)and eNOS activator calcimycin(A23187)failing to increase free NO level in human umbilical vein endothelial cell line(HUV-EC-C),although the reagents were confirmed to work normally in the primary human umbilical vein endothelial cells(primary HUVECs)and RAW 264.7 macrophage *** research suggested that these unusual behaviors might be attributed to the cellular microenvironments including both the NO synthase(NOS)level and the endogenous glutathione(GSH)*** manipulating eNOS level in both cells restores the expected response,while decreasing GSH level restores the ability of DEA$NONOate to increase NO level in *** results reveal that the cellular microenvironment has a profound impact on pharmacological *** study suggests GSH as a reservoir for NO in live cells and highlights the value of chemical probes as valuable tools to reveal microenvironmentdependent pharmacological effects.

关键词： Nitric oxide modulator Drug screen Fluorescence imaging Microenvironment Endothelial cell

Phylogenetic and Structural Analysis of Major Surface Proteins Hemagglutinin and Neuraminidase of Novel Avian Influenza Virus A H7N9 from Chinese Patient

在线全文

学校读者我要写书评

暂无评论

Chemical Research in Chinese Universities 2013年第5期29卷 934-940页

作者： YUAN xiao-hui WANG ying-chen QU Zhang-yi REN jia-yi WU xiao-min WANG Jing-fei Department of Microbiology Public Health College Harbin Medical University Harbin 150081 P. R. China Institute of Pathogen Biology Chinese Academy of Medical Sciences & Peking Union Medical College Beijing 100176 P R. China Key Laboratory of Resource and Plant Biology of Anhui Province College of Life Science Huaibei Normal University Huaibei 235000 P. R. China Harbin Veterinary Research Institute Chinese Academy of Agricultural Sciences Harbin 150081 P R. China

This research reveals the phylogenetic history and structural information of the hemagglutinin（HA） and neuraminidase（NA） from novel avian influenza virus A/Hangzhou/1/2013（HTN9_2013） strain from human infected in China. Strains closely related to the HTN9 2013 strain were obtained from Nation Center for Biotechnology Information（USA）-basic local alignment search tool（NCBI-BLAST） searching, and the phylogenetic trees were con- structed. The 3D structures of HA and NA from H7N9 2013 strain were built by homology modeling technology, and molecular dynamics（MD） simulations were performed on the high-performance computer cluster. Characteristic amino acid sites were then screened from multiple sequence alignment（MSA） via home-made Python script and mapped onto the 3D structures. The thermodynamic characteristic root-mean-square-fluctuation （RMSF） of these sites in the structure was also analyzed with MD trajectories. The HA of HTN9_2013 strain is closely related to the A/duck/Zhejiang/12/2011 strain isolated in China, while the NA of HTN9 2013 strain is mostly related to the A/mallard/Czech Republic/13438-29K/2010 strain isolated in Europe. The 3D structures of HA and NA from H7N9 2013 stain are mostly identical to the existing structure of H7 and N9. A total of 11 and 14 characteristic ami- no acid sites were identified in HA and NA, respectively, in HTN9_2013. Structural analysis indicates that certain sites in the top region of HA are important, at which the mutation of some amino acids can impact the receptor bin- ding that may be related to its infection of human beings.

关键词： Avian influenza virus Hemagglutinin Neuraminidase Homology modeling Phylogenetic

Preparation of ultrafine silica from potash feldspar using sodium carbonate roasting technology

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 2016年第8期23卷 966-975页

作者： jia-nan Liu xiao-yi Shen Yan Wu Jun Zhang Yu-chun Zhai School of Metallurgy Northeastern University School of Resources and Materials Northeastern University at Qinhuangdao

A novel process was developed for the preparation of ultrafine silica from potash feldspar. In the first step, potash feldspar was roasted with Na_2CO_3 and was followed by leaching using Na OH solution to increase the levels of potassium, sodium, and aluminum in the solid residue. The leaching solution was then carbonated to yield ultrafine silica. The optimized reaction conditions in the roasting process were as follows： an Na_2CO_3-to-potash feldspar molar ratio of 1.1, a reaction temperature of 875°C, and a reaction time of 1.5 h. Under these conditions, the extraction rate of SiO_2 was 98.13%. The optimized carbonation conditions included a final solution p H value of 9.0, a temperature of 40°C, a CO_2 flow rate of 6 m L/min, a stirring intensity of 600 r/min, and an ethanol-to-water volume ratio of 1：9. The precipitation rate and granularity of the SiO_2 particles were 99.63% and 200 nm, respectively. We confirmed the quality of the obtained ultrafine silica by comparing the recorded indexes with those specified in Chinese National Standard GB 25576―2010.

关键词： potash feldspar sodium carbonate roasting silica optimization