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Which lamp will be optimum to eye? Incandescent,fluorescent or LED etc

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International Journal of Ophthalmology(English edition) 2014年第1期7卷 163-168页

作者： Liang Chen xiao-wei zhang Department of Lighting Upright Lighting LLC Department of Ophthalmology Children’s Medical Center of Dallas

Low frequency flicker,high frequency flicker,strong light,strong blue light,infrared,ultraviolet,electromagnetic radiation,ripple flicker and dimming flicker produced by different lamps have negative impact on vision,eyes and health. Negative impact on eyes resulting in myopia or cataract etc: the solution is to remove all the negative factors by applying upright lighting technology and that is optimum to vision,eyes and health.

关键词： low frequency flicker high frequency flicker strong light infrared ultraviolet electromagnetic radiation ripple flicker dimming flicker

Suppression of spermatogenesis by testosterone undecanoate-loaded injectable in situ-forming implants in adult male rats

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Asian Journal of Andrology 2016年第5期18卷 791-797页

作者： xiao-wei zhang Chong zhang wei zhang Dan Yang Shu Meng Ping Wang Jing Guo Dan-Hua Liu Drug Research Laboratory Liaoning Research Institute of Family Planning Huanggu District Shenyang China

We have investigated the feasibility of administration of testosterone undecanoate （TU）-Ioaded injectable in situ-forming implant （ISFI） for contraception in adult male Sprague-Dawley rats. Male rats were treated with vehicle, TU-Ioaded ISFIs （540, 270 and 135 mg TU kg-1） or TU injections （45 mg TU kg-1 every 30 days） for 120 days. Fertility tests served for determining infertility or restoration of fertility in treated rats. Serum testosterone concentration, epididymal sperm count, motility, morphology, and histology of the testis were monitored. The TU-Ioaded ISFIs increased serum testosterone levels in rats steadily without fluctuation over 3 months. One month after TU administration, the epididymal sperm count decreased significantly in all experimental groups. After 3 months, the animals treated with 270 and 135 mg kg-~ TU-Ioaded ISFIs were 100% infertile, and no implantation sites were produced in the mated females. However, some of males treated with 540 mg kg-~ ISFI or TU injections were still fertile but numbers of implantation sites were also significantly lower than control values. TU-Ioaded ISFI at an appropriate dose has potential as a long-acting male contraceptive drug that suppresses spermatogenesis consistently over a period of 3 months.

关键词： in situ-forming implants male contraception rats spermatogenesis testosterone undecanoate

NRGA1, a Putative Mitochondrial Pyruvate Carrier, Mediates ABA Regulation of Guard Cell Ion Channels and Drought Stress Responses in Arabidopsis

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Molecular Plant 2014年第10期7卷 1508-1521页

作者： Chun-Long Li Mei Wang xiao-Yan Ma wei zhang Key Laboratory of Plant Cell Engineering and Germplasm Innovation Ministry of Education School of Life Science Shandong UniversityJinan 250100 China

Abscisic acid （ABA） regulates ion channel activity and stomatal movements in response to drought and other stresses. Here, we show that the Arabidopsis thaliana gene NRGA1 is a putative mitochondrial pyruvate carrier which negatively regulates ABA-induced guard cell signaling. NRGA1 transcript was abundant in the A. thaliana leaf and par- ticularly in the guard cells, and its product was directed to the mitochondria. The heterologous co-expression of NRGA1 and AtMPC1 in yeast complemented a loss-of-function mitochondrial pyruvate carrier （MPC） mutant. The nrgal loss-of- function mutant was very sensitive to the presence of ABA in the context of stomatal movements, and exhibited a height- ened tolerance to drought stress. Disruption of NRGA1 gene resulted in increased ABA inhibition of inward K＋ currents and ABA activation of slow anion currents in guard cells. The nrgal/NRGA1 functional complementation lines restored the mutant＇s phenotypes. Furthermore, transgenic lines of constitutively overexpressing NRGA1 showed opposite stomatal responses, reduced drought tolerance, and ABA sensitivity of guard cell inward K＋ channel inhibition and anion channel activation. Our findings highlight a putative role for the mitochondrial pyruvate carrier in guard cell ABA signaling in response to drought.

关键词： NRGAI mitochondrial pyruvate carrier ABA guard cell stomata inward K+ channel slow anion channel drought stress.

MdbHLH162 connects the gibberellin and jasmonic acid signals to regulate anthocyanin biosynthesis in apple

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Journal of Integrative Plant Biology 2024年第2期66卷 265-284页

作者： Jian-Ping An Rui-Rui Xu xiao-Na Wang xiao-wei zhang Chun-Xiang You Yuepeng Han Apple technology innovation center of Shandong Province College of Horticulture Science and EngineeringShandong Agricultural UniversityTai-An 271018China CAS Key Laboratory of Plant Germplasm Enhancement and Specialty Agriculture Wuhan Botanical GardenHubei Hongshan LaboratoryThe Innovative Academy of Seed Design of Chinese Academy of SciencesWuhan 430074China College of Biology and Oceanography Weifang UniversityWeifang 261061China

Anthocyanins are secondary metabolites induced by environmental stimuli and developmental *** positive regulators of anthocyanin biosynthesis have been reported,whereas the anthocyanin repressors have been *** the signal transduction pathways of gibberellin(GA)and jasmonic acid(JA)and their regulation of anthocyanin biosynthesis have been investigated,the cross-talk between GA and JA and the antagonistic mechanism of regulating anthocyanin biosynthesis remain to be *** this study,we identified the anthocyanin repressor MdbHLH162 in apple and revealed its molecular mechanism of regulating anthocyanin biosynthesis by integrating the GA and JA ***162 exerted passive repression by interacting with MdbHLH3 and MdbHLH33,which are two recognized positive regulators of anthocyanin ***162 negatively regulated anthocyanin biosynthesis by disrupting the formation of the anthocyanin-activated MdMYB1-MdbHLH3/33complexes and weakening transcriptional activation of the anthocyanin biosynthetic genes MdDFR and MdUF3GT by MdbHLH3 and *** GA repressor MdRGL2a antagonized MdbHLH162-mediated inhibition of anthocyanins by sequestering MdbHLH162 from the MdbHLH162-MdbHLH3/33 *** JA repressors MdJAZ1 and MdJAZ2 interfered with the antagonistic regulation of MdbHLH162 by MdRGL2a by titrating the formation of the MdRGL2a-MdbHLH162 *** findings reveal that MdbHLH162 integrates the GA and JA signals to negatively regulate anthocyanin *** study provides new information for discovering more anthocyanin biosynthesis repressors and explores the cross-talk between hormone signals.

关键词： anthocyanin biosynthesis bHLH transcription factor gibberellin jasmonic acid regulatory network transcriptional regulation

Review on thermal performance of phase change energy storage building envelope

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Chinese Science Bulletin 2009年第6期54卷 920-928页

作者： WANG Xin zhang YinPing xiao wei ZENG RuoLang zhang QunLi DI HongFa Department of Building Science Tsinghua University Beijing 100084 China

Improving the thermal performance of building envelope is an important way to save building energy consumption. The phase change energy storage building envelope is helpful to effective use of re-newable energy, reducing building operational energy consumption, increasing building thermal com-fort, and reducing environment pollution and greenhouse gas emission. This paper presents the con-cept of ideal energy-saving building envelope, which is used to guide the building envelope material selection and thermal performance design. This paper reviews some available researches on phase change building material and phase change energy storage building envelope. At last, this paper pre-sents some current problems needed further research.

关键词：建筑围护结构热性能相变蓄能综述可再生能源建筑能耗业务建设

Accurate GW_(0) band gaps and their phonon-induced renormalization in solids

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Chinese Physics B 2021年第11期30卷 82-93页

作者： Tong Shen xiao-wei zhang Min-Ye zhang Hong Jiang Xin-Zheng Li Interdisciplinary Institute of Light-Element Quantum Materials Research Center for Light-Element Advanced Materialsand Collaborative Innovation Center of Quantum MatterPeking UniversityBeijing 100871China State Key Laboratory for Artificial Microstructure and Mesoscopic Physics Frontier Science Center for Nano-optoelectronics and School of PhysicsPeking UniversityBeijing 100871China International Center for Quantum Materials Collaborative Innovation Center of Quantum Matterand School of PhysicsPeking UniversityBeijing 100871China Beijing National Laboratory for Molecular Sciences College of Chemistry and Molecular EngineeringPeking UniversityBeijing 100871China

Recent years,huge progress of first-principles methods has been witnessed in calculating the quasiparticle band gaps,with many-body perturbation theory in the GW approximation being the standard choice,where G refers to Green’s function and W denotes the dynamically screened Coulomb ***,the completeness of the basis set has been extensively discussed,but in practice far from carefully *** the static description of the nuclei,the electron–phonon interactions(EPIs)are ubiquitous,which cause zero-point renormalization(ZPR)of the band ***,to obtain high quality band gaps,one needs both accurate quasiparticle energies and accurate treatments of *** this article,we review methods on *** completeness of the basis set is analyzed in the framework of linearized augmented plane waves,by adding high-energy local orbitals(HLOs).The electron–phonon matrix elements and self-energy are discussed,followed by the temperature dependence of the band gaps in both perturbative and non-perturbative *** of such an analysis on bulk wurtzite BeO and monolayer honeycomb BeO are *** HLOs widens their GW_(0) band gaps by∼0.4 eV while ZPR narrows them by similar *** influences cancel each other,which explains the fortuitous agreement between experiment and theory when the basis set is incomplete and the EPIs are *** phonon-induced renormalization,a term often neglected in calculations of the band gaps,is also emphasized by its large magnitude.

关键词： quasiparticle band gaps electron-phonon interactions basis-set completeness Beryllium oxide

Operando measurement of lattice deformation profiles of synchrotron radiation monochromator

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Nuclear Science and Techniques 2024年第7期35卷 8-19页

作者： Yue zhang Zhong-Liang Li Shang-Yu Si Lian Xue Hong-Xin Luo xiao-wei zhang Jun Hu Shanghai Synchrotron Radiation Facility Shanghai Advanced Research InstituteChinese Academy of SciencesShanghai201204China ShanghaiTech University Shanghai201210China University of the Chinese Academy of Sciences Beijing100049China Beijing Synchrotron Radiation Facility Institute of High Energy PhysicsChinese Academy of ScienceBeijing100049China

This study presents a new method for characterizing the thermal lattice deformation of a monochromator with high precision under service conditions and first reports the operando measurements of nanoscale thermal lattice deformation on a double-crystal monochromator at different incident *** nanoscale thermal lattice deformation of the monochromator first crystal was obtained by analyzing the intensity of the distorted DuMond *** diagrams of the 333 diffraction index,sensitive to lattice deformation,were obtained directly using a 2D detector and an analyzer crystal orthogonal to the *** increasing incident power and power density,the maximum height of the lattice deformation increased from 3.2 to 18.5 nm,and the deformation coefficient of the maximum height increased from 1.1 to 3.2 nm/*** maximum relative standard deviation was 4.2%,and the maximum standard deviation was 0.1 *** on the measured thermal deformations,the flux saturation phenomenon and critical point for the linear operation of the monochromator were predicted with increasing incident *** study provides a simple solution to the problem of the lower precision of synchrotron radiation monochromator characterizations compared to simulations.

关键词： Synchrotron radiation Monochromator Lattice deformation X-ray dynamic diffraction

Aspirin increases susceptibility of Helicobacter pylori to metronidazole by augmenting endocellular concentrations of antimicrobials

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World Journal of Gastroenterology 2009年第8期15卷 919-926页

作者： xiao-Ping zhang wei-Hong Wang Yu Tian Wen Gao Jiang Li Department of Gastroenterology Peking University First Hospital Beijing 100034 China

AIM： To investigate the increasing the susceptibility pylon） to metronidazole. mechanisms of aspirin of Helicobacter pylori （H METHODS： Hpylori reference strain 26695 and two metronidazole-resistant isolates of H pylori were included in this study. Strains were incubated in Brucella broth with or without aspirin （1 mmol/L）. The rdxA gene of Hpylori was amplified by PCR and sequenced. The permeability of Hpylori to antimicrobials was determined by analyzing the endocellular radioactivity of the cells after incubated with [7-^3H]-tetracycline. The outer membrane proteins （OMPs） of Hpylori 26695 were depurated and analyzed by SDS-PAGE. The expression of 5 porins （hopA, hopB, hopC, hopD and hopE） and the putative RND efflux system （hefABC） of H pylori were analyzed using real-time quantitative PCR. RESULTS： The mutations in rdxA gene did not change in metronidazole resistant isolates treated with aspirin. The radioactivity of H pylori increased when treated with aspirin, indicating that aspirin improved the permeability of the outer membrane of H pylori. However, the expression of two OMP bands between 55 kDa and 72 kDa altered in the presence of *** expression of the mRNA of hopA, hopB, hopC, hopD, hopE and herA, hefB, hefC of H pylori did not change when treated with aspirin. CONCLUSION： Although aspirin increases the susceptibility of H pylori to metronidazole, it has no effect on the mutations of rdxA gene of Hpylori. Aspirin increases endocellular concentrations of antimicrobials probably by altering the OMP expression.

关键词： Helicobacter pylori Aspirin Metronidazole Resistance Minimum inhibitory concentrations

Migration regularities of impurity aluminum and copper in purification of metal lanthanum by solid-state electrotransport

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Rare Metals 2021年第8期40卷 2307-2312页

作者： Zhi-Qiang Wang Zong-An Li Jia-Min Zhong De-Hong Chen xiao-wei zhang Lin Zhou National Engineering Research Center for Rare Earth Materials Grirem Advanced Materials Co.Ltd.General Research Institute for Nonferrous MetalsBeijing100088China

In view of the previous studies on the migrations of impurity aluminum(Al)and copper(Cu)in purification of rare earth metal by solid-state electrotransport(SSE),there are still some questions about that which direction they migrate to and whether there are significant migrations or *** metal lanthanum(La)was used as research object,and the effects of migration temperature and time on the distributions and migration regularities of impurity Al and Cu were investigated in the present study by increasing concentration of impurity Al and Cu in raw metal *** impurity migration direction and removal difficulty were intuitively judged by the residual rate distribution curve of *** is indicated that metal impurity Al and Cu in metal La at 800℃ with direct current are found to significantly migrate to anode and their residual rates near cathode decrease with the increase in migration temperature and prolongation of migration *** relatively large vapor pressure of Al and Cu makes their residual rate distribution curves being low in middle and high in *** metal La was continuously purified for 100 h at 800℃ by SSE,the residual rates of impurity Al and Cu at 20 mm from cathode are 68.43%and 57.43%,respectively,showing that Cu is much easier to be removed than Al.

关键词： Solid-state electrotransport Purification Residual rate Rare earth metal Lanthanum