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Role of nutrition in diabetes mellitus and infections

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World Journal of Clinical Cases 2025年第3期13卷 1-8页

作者： Xue-Lu Yu Li-Yun Zhou xiao Huang Xin-Yue Li Ming-Ke wang Ji-Shun Yang Naval Medical Center of PLA Naval Medical UniversityShanghai 200052China

In this editorial,we have commented on the article that has been published in the recent issue of World Journal of Clinical *** authors have described a case of unilateral thyroid cyst and have opined that the acute onset of infection may be linked to diabetes mellitus(DM).We have focused on the role of nutrition in the association between DM and *** with DM are at a high risk of infection,which could also be attributed to nutrition-related *** interventions for patients with diabetes are mainly based on a low-calorie diet,which can be achieved by adhering to a low-carbohydrate ***,dietary fiber supplementation is recommended to maintain the diversity of the gut ***,high-quality protein can prevent the increased risk of infection due to *** of vitamins C,vitamins A,vitamins D,and folic acid improves blood sugar control and facilitates immune *** deficiencies augment the risk of infection,but the relationship with diabetes is mostly U-shaped and a good intake should be maintained.

关键词： Diabetes mellitus Infection Macronutrients Vitamins Minerals

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三种茶香猪肉干品质的比较分析

山地农业生物学报 2016年第6期35卷 68-72页

作者：钟明跃魏正松李晓松尹杰汪艳霞贵州大学农学院贵州贵阳550025 贵州大学茶叶工程与技术中心贵州贵阳550025

本文通过对在制作中分别添加红茶粉、青茶粉和绿茶粉的三种不同猪肉干产品进行感官审评及对含水量、蛋白质含量、脂肪含量和猪肉干中的茶多酚含量等品质成分进行测定,结果表明:综合色泽、口感和风味,添加茶粉提高了猪肉干产品的品质,三... 详细信息

本文通过对在制作中分别添加红茶粉、青茶粉和绿茶粉的三种不同猪肉干产品进行感官审评及对含水量、蛋白质含量、脂肪含量和猪肉干中的茶多酚含量等品质成分进行测定,结果表明:综合色泽、口感和风味,添加茶粉提高了猪肉干产品的品质,三种猪肉干产品中,青茶猪肉干品质最佳;相同的制作时间,青茶猪肉干的含水量最低,在适口的含水量范围,含水量低利于猪肉干品质保鲜;添加茶粉,各种类猪肉干产品中蛋白质含量均有降低,但并不显著;除红茶猪肉干较未添加茶粉猪肉干脂肪含量降低,青茶猪肉干和绿茶猪肉干中脂肪含量均有提高,增加了猪肉干产品的适口性;经过高温制作,茶香猪肉干中茶多酚含量均降低,青茶猪肉干茶多酚含量保留量最多,且降低率最小。

关键词：猪肉干茶香品质

Experimental study on the microstructure and nanomechanicai properties of the wing membrane of dragonfly

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Acta Mechanica Sinica 2007年第3期23卷 281-285页

作者： Kewei xiao Ke Bai Wensheng wang Fan song State Key Laboratory of Nonlinear Mechanics (LNM) Institute of Mechanics Chinese Academy of SciencesBeijing 100080 China Department of Chemical Biology School of Pharmaceutical SciencesPeking University Health Science CenterBeijing 100083 China Department of Mechanical Engineering Tongji University Shanghai 200092 China

Detailed investigations on the microstructure and the mechanical properties of the wing membrane of the dragonfly are carried out. It is found that in the direction of the thickness the membrane was divided into three layers rather than a single entity as traditionally considered, and on the surfaces the membrane displays a random distribution rough microstructure that is composed of numerous nanometer scale columns coated by the cuticle wax secreted. The characteristics of the surface structure are measured and described. The mechanical properties of the membranes taken separately from the wings of live and dead dragonflies are investigated by the nanoindentation technique. The Young＇s moduli obtained here are approximately two times greater than the previous result, and the reasons that yield the difference are discussed.

关键词： Microstructure Surface structure Mechanical properties Surface analysis

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旧院黑鸡屠宰性能及肉品质测定

四川农业大学学报 2017年第2期35卷 256-259页

作者：李菁菁邓中勇杨朝武任鹏蒋小松王也刘益平四川农业大学动物科技学院成都611130 四川省畜牧科学研究院成都610066

【目的】旨在明确旧院黑鸡屠体的经济价值,为旧院黑鸡的进一步选育提供理论参考依据。【方法】分别在90、120和150日龄随机选择旧院黑鸡公、母各20只进行屠宰性能及肉品质测定。【结果】结果表明,随着饲养日龄的增长,旧院黑鸡胸肌和腿... 详细信息

【目的】旨在明确旧院黑鸡屠体的经济价值,为旧院黑鸡的进一步选育提供理论参考依据。【方法】分别在90、120和150日龄随机选择旧院黑鸡公、母各20只进行屠宰性能及肉品质测定。【结果】结果表明,随着饲养日龄的增长,旧院黑鸡胸肌和腿肌逐渐增重,公鸡屠宰率降低,而母鸡屠宰率升高,150日龄时旧院黑鸡屠宰性能较佳。在肉品质方面,粗蛋白含量随日龄增长而降低,肌苷酸、肌内脂肪含量随日龄增长而增加。根据肉品质相关指标综合分析,最佳肉品质在120日龄左右。【结论】综合各项指标分析,旧院黑鸡最佳上市日龄在120日龄左右。

关键词：旧院黑鸡屠宰性能肉品质

ITO thin films prepared by electron beam evaporation with End-Hall ion source assisted without heating to the substrate

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光学精密工程 2005年第4期13卷 397-402页

作者： GAO Jin-song XU Ying wang xiao-yi wang Tong-tong Optical Technology and Research Center Changchun Institute of Optics Fine Mechanics and Physics Chinese Academy of Sciences Changchun 130022 China

ITO （indium oxide doped with tin） thin films were deposited on glass substrates by using ITO pellet with a composition of w（In2O3）=90% and w（SnO2）=10% by electron beam evaporated with End-Hall ion source assisted without extra heating. The rate of deposition and flow rate of oxygen were measured and changed to obtain the best properties of ITO thin films. Furthermore, the post annealing process was done in vacuum at different annealing temperatures for 2 h and at 400℃ for different keeping time, respectively. The relation between optical, electrical properties and structure was discussed in detail.

关键词： ITO 薄膜电子束离子源

De novo synthesis of atropisomeric benzofurans via Cu/SPDO complex catalyzed asymmetric formal [3 + 2] annulation

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Science China Chemistry 2025年第1期 174-180页

作者： Fan-xiao Meng Xing-Yu wang Ka Lu Ju-song Yang Fu-Min Zhang Ai-Jun Ma Bao Du Yong-Qiang Tu State Key Laboratory of Applied Organic Chemistry College of Chemistry and Chemical Engineering Lanzhou University School of Chemistry and Chemical Engineering Shanghai Jiao Tong University School of Biotechnology and Health Sciences Wuyi University

Herein, the de novo synthesis of atropisomeric benzofurans through the Cu/spirocyclic-pyrrolidine-oxazoline(SPDO) complex catalyze asymmetric formal [3 + 2] cycloaddition between quinones and ynamides is explored, producing a range of structurally diverse axially chiral benzofurans in satisfactory yields with good to excellent enantioselectivities. Furthermore, density functional theory calculations were applied to explain the possible reaction mechanism.

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磁性纳米材料与磁场效应加速骨损伤修复

中国组织工程研究 2025年第4期29卷 827-838页

作者：肖放黄雷王琳华中科技大学同济医学院附属协和医院组织工程与再生医学研究中心湖北省武汉市430022 华中科技大学同济医学院附属协和医院检验科湖北省武汉市430022

背景:磁性纳米材料具有促进干细胞成骨分化和抑制破骨细胞形成等生物活性,并在磁场协同下有效促进损伤骨组织愈合,在骨损伤修复中具有广阔的应用前景。目的:综述磁性纳米材料与磁场促进骨修复的作用机制,及其在骨损伤修复领域的研究进... 详细信息

背景:磁性纳米材料具有促进干细胞成骨分化和抑制破骨细胞形成等生物活性,并在磁场协同下有效促进损伤骨组织愈合,在骨损伤修复中具有广阔的应用前景。目的:综述磁性纳米材料与磁场促进骨修复的作用机制,及其在骨损伤修复领域的研究进展。方法:在PubMed和Web of Science数据库中进行相关文献检索,检索词为“magnetic nanomaterials,magnetic field,bone repair,bone tissue engineering,stem cell,osteoblast,osteoclast”。检索文献时限为2003-2023年,将其进行筛选和分析,最终纳入98篇文献进行分析。结果与结论:①磁性纳米材料具有促成骨细胞分化、抑制破骨细胞形成和调节免疫微环境等生物效应;此外,磁性纳米材料可调节组织工程支架的机械性能和表面形貌等理化性质,并赋予其磁性,有利于调控干细胞的黏附、增殖与成骨分化。②磁场具有调控细胞内多条信号通路发挥促成骨细胞分化、抑制破骨细胞形成和刺激血管生成等生物学效应,从而加速损伤的骨组织愈合。③磁性纳米材料与磁场的联合应用,通过激活机械转导、增加细胞内磁性纳米粒子含量、增强微磁场效应等加速骨损伤修复,为骨组织工程的研究提供了新的思路。④磁场在临床骨折、骨质疏松症和骨关节炎疾病的治疗中展现出确切疗效,促进骨组织生长、减轻骨质流失和缓解疼痛,改善患者的生活质量。⑤磁性纳米材料与磁场在骨损伤修复与再生中应用潜力大,但磁性纳米材料、磁场和细胞之间的相互作用机制尚未完全阐明,而且磁场调控细胞内分子事件的关键参数,包括磁场类型、强度、频率、作用时间和作用方式等,以及特定磁场对骨细胞的精确生物效应和潜在机制仍有待明确。⑥未来需要进一步关注其对损伤组织微环境中的破骨细胞、神经、血管和免疫细胞的影响,而关于磁性材料用于人体安全性问题,有待系统性研究其分布、代谢以及急性和慢性毒性等。

关键词：磁性纳米材料磁场骨修复骨组织工程干细胞成骨细胞破骨细胞

Theoretical calculation and experimental study on the interaction mechanism between TKX-50 and AP

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Defence Technology（防务技术） 2020年第4期16卷 825-833页

作者： Jun Tao xiao-Feng wang Kun Zhang Xue-song Feng The Second Department Xi'an Modern Chemistry Research InstituteXi'an 710065China

The combination of 5,5'-bistetrazole-1,1'-diolate(TKX-50) and ammonium perchlorate(AP) can make greater use of the chemical energy of TKX-50 based energetic *** research on the interaction mechanism between TKX-50 and AP is very important for designing TKX-50-AP compounds and judging the formation feasibility of composite particles,which can lay a theoretical foundation for the preparation of TKX-50-AP mixed crystals and the application of TKX-50 in propellant,propellant and ***,in order to research the interaction mechanism between TKX-50 and AP,density-functional theory calculation was applied to optimize three configurations of TKX-50-AP *** geometry structure,electrostatic potential and binding energy of the compounds were predicted,and the electronic density topological analysis was also carried *** TKX-50-AP mixed crystals structures were constructed,and the radial distribution function of H-O and H-N in mixed crystals was ***,solvent/non-solvent method was applied to prepare TKX-50-AP composites,and the infrared spectro scopy and the non-isothermal decomposition perfo rmance of the composites were *** show that the superposition of positive charges in TKX-50 molecule and negative charges in AP makes the electrostatic potential distributions of TKX-50-AP compounds different from that of TKX-50 and *** interaction energies of TKX-50-AP 1,TKX-50-AP 2 and TKX-50-AP 3 are 39.743 kJ/mol,61.206 kJ/mol and 27.702 kJ/mol,*** interaction between TKX-50 molecules and AP molecules in TKX-50-AP mixed crystals both depends on hydrogen bonds and van der Waals force,and the number and strength of hydrogen bonds are significantly greater than that of van der Waals *** composition of AP and TKX-50 makes the absorption peak of the five-membered rings and NH_3 OH^+ of TKX-50 shift to low wavenumber in the infrared *** general,TKX-50 interacts with AP via hydrogen bonds and va

关键词： 5,5'-bistetrazole-1,1'-diolate Ammonium perchlorate Density-functional theory Molecular dynamics Hydrogen bond

Recent Advances in Tumor Microenvironment Hydrogen Peroxide-Responsive Materials for Cancer Photodynamic Therapy

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Nano-Micro Letters 2020年第1期12卷 208-234页

作者： Nan Yang Wanyue xiao Xuejiao song Wenjun wang xiaochen Dong Key Laboratory of Flexible Electronics(KLOFE)and Institute of Advanced Materials(IAM) School of Physical and Mathematical SciencesNanjing Tech University(Nanjing Tech)Nanjing 211800People’s Republic of China School of Physical Science and Information Technology Liaocheng UniversityLiaocheng 252059People’s Republic of China School of Chemistry and Materials Science Nanjing University of Information Science and TechnologyNanjing 210044People’s Republic of China

Photodynamic therapy(PDT),as one of the noninvasive clinical cancer phototherapies,suffers from the key drawback associated with hypoxia at the tumor microenvironment(TME),which plays an important role in protecting tumor cells from damage caused by common *** concentration of hydrogen peroxide(H2O2),one of the hallmarks of TME,has been recognized as a double-edged sword,posing both challenges,and opportunities for cancer *** promising perspectives,strategies,and approaches for enhanced tumor therapies,including PDT,have been developed based on the fast advances in H2O2-enabled theranostic *** this review,we outline the latest advances in H2O2-responsive materials,including organic and inorganic materials for enhanced ***,the challenges and opportunities for further research on H2O2-responsive anticancer agents are envisioned.

关键词： Tumor microenvironment H2O2-responsive Cancer Nanomaterials Photodynamic therapy