检索结果-南通市图书馆

维普期刊数据库

Mechanical properties of hot-pressed high-entropy diboride-based ceramics

在线全文

学校读者我要写书评

暂无评论

Journal of Advanced Ceramics 2020年第4期9卷 503-510页

作者： Ji-Xuan Liu xiao-qin shen Yue Wu Fei Li Yongcheng Liang Guo-Jun Zhang State Key Laboratory for Modification of Chemical Fibers and Polymer Materials College of Materials Science and EngineeringCollege of SciencesInstitute of Functional MaterialsDonghua UniversityShanghai201620China

High-entropy ceramics attract more and more attention in recent ***,mechanical properties especially strength and fracture toughness for high-entropy ceramics and their composites have not been comprehensively *** this work,high-entropy(Ti0.2Zr0.2Hf0.2Nb0.2Ta 0.2)B2(HEB)monolithic and its composite containing 20 vol%SiC(HEB–20SiC)are prepared by hot *** addition of SiC not only accelerates the densification process but also refines the microstructure of HEB,resulting in improved mechanical *** obtained dense HEB and HEB–20SiC ceramics hot pressed at 1800℃exhibit four-point flexural strength of 339±17 MPa and 447±45 MPa,and fracture toughness of 3.81±0.40 MPa·m1/2 and 4.85±0.33 MPa·m1/2 measured by single-edge notched beam(SENB)*** deflection and branching by SiC particles is considered to be the main toughening mechanisms for the HEB–20SiC *** hardness Hv0.2 of the sintered HEB and HEB–20SiC ceramics is 23.7±0.7 GPa and 24.8±1.2 GPa,*** the increase of indentation load,the hardness of the sintered ceramics decreases rapidly until the load reaches about 49 N,due to the indentation size *** on the current experimental investigation it can be seen that the room temperature bending strength and fracture toughness of the high-entropy diboride ceramics are within ranges commonly observed in structure ceramics.

关键词： high-entropy ceramics high-entropy diboride flexural strength fracture toughness indentation size effect

维普期刊数据库

Tuning the interfacial reaction environment via pH-dependent and induced ions to understand C–N bonds coupling performance in NO3- integrated CO2 reduction to carbon and nitrogen compounds over dual Cu-based N-doped carbon catalyst

在线全文

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2025年第1期100卷 273-285页

作者： Tianhang Zhou Chen shen Zhenghao Wu Xingying Lan Yi xiao College of Carbon Neutrality Future Technology State Key Laboratory of Heavy Oil Processing China University of Petroleum (Beijing) Institute of Materials Science TU Darmstadt Department of Chemistry Xi'an Jiaotong-Liverpool University Department of Mechanical and Mechatronics Engineering and Waterloo Institute of Nanotechnology University of Waterloo Waterloo

Dual atomic catalysts （DAC）,particularly copper （Cu2）-based nitrogen （N） doped graphene,show great potential to effectively convert CO2and nitrate （NO3-） into important industrial chemicals such as ethylene,glycol,acetamide,and urea through an efficient catalytical process that involves C–C and C–N ***,the origin of the coupling activity remained unclear,which substantially hinders the rational design of Cu-based catalysts for the N-integrated CO2reduction reaction （CO2RR）.To address this challenge,this work performed advanced density functional theory calculations incorporating explicit solvation based on a Cu2-based N-doped carbon (Cu2N6C10) catalyst for *** calculations are aimed to gain insight into the reaction mechanisms for the synthesis of ethylene,acetamide,and urea via coupling in the interfacial reaction *** to the sluggishness of CO2,the formation of a solvation electric layer by anions （F-,Cl-,Br-,and I-） and cations (Na+,Mg2+,K+,and Ca2+) leads to electron transfer towards the Cu *** process significantly accelerates the reduction of *** results reveal that*CO intermediates play a pivotal role in N-integrated ***,the Cu2-based N-doped carbon catalyst examined in this study has demonstrated the most potential for C–N coupling to *** findings reveal that through the process of a condensation reaction between*CO and NH2OH for urea synthesis,*NO3-is reduced to*NH3,and*CO2to*CCO at dual Cu atom *** dual-site reduction facilitates the synthesis of acetamide through a nucleophilic reaction between NH3and the ketene ***,we found that the I-and Mg2+ions,influenced by pH,were highly effective for acetamide and ammonia synthesis,except when F-and Ca2+were ***,the mechanisms of C–N bond formation were investigated via ab-initio molecular dynamics simulations,and we found that adjusting the micro-environment can change the dominant side reaction,shift

关键词： pH-dependent micro-environments C–N coupling Dual Cu-based nitrogen carbon catalysts Explicit solvation model Ion stabilizer AIMD

Synergistically enhanced ORR and HER performance on Co-N-C coupled in-situ generated PtCo intermetallic

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2025年第1期100卷 721-729页

作者： Guanyu Luo Min Song Lulu An xiao Huang Qian Zhang Chenhao Zhang Tao shen Shuang Wang Deli Wang Key Laboratory of Material Chemistry for Energy Conversion and Storage (Huazhong University of Science and Technology) Ministry of Education School of Chemistry and Chemical Engineering Huazhong University of Science and Technology

Integrating multi-scale sites in a composite catalyst is vital to realize efficient ***,a synergistic composite catalyst consisting of Co atomic sites and in-situ generated PtCo intermetallic compounds （IMCs）(o-PtCo@CoNC) is proposed through Co pre-anchoring and subsequent impregnation-reduction *** loading of Co atoms provides a chance for in-situ generating PtCo ordered intermetallic *** remaining Co single atoms and PtCo IMCs construct synergistic electrocatalytic *** from the ordered structure,synergistic effect of Pt Co IMCs and Co single atoms,o-PtCo@CoNC exhibits excellent electrocatalytic performance for oxygen reduction reaction （ORR） and hydrogen evolution reaction （HER） with mass activity of 1.21 A mgPt-1（at 0.9 V） and5.70 A mgPt-1（at an overpotential of 100 mV）,***,o-PtCo@CoNC delivers negligible loss of half-wave potential and overpotential during long-term stability test in acid solutions,with 13 mV decay after 50,000 potential cycles for ORR and a 2.7 mV decay after 20,000 potential cycles for *** integration strategy of single-atomic sites coupled IMCs paves the way for enhancing the activity and durability of Pt-based electrocatalysts.

关键词： Electrolytic reduction

Metal nanoparticles decorated CoFe-(oxy)hydroxysulfides nanosheets fabricated by a general strategy for electrocatalytic water splitting

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2025年第1期100卷 26-38页

作者： xiaodong Yang Haochen shen xiaoming xiao Zhichao Li Qi Zhou Wei Yang Bin Jiang Yongli Sun Luhong Zhang Zhenhua Yan School of Chemical Engineering and Technology Tianjin University Key Laboratory of Advanced Energy Materials Chemistry (Ministry of Education) Nankai University

This study presents a novel method to fabricate metal-decorated,sulfur-doped layered double hydroxides （M/SLDH） through spontaneous redox and sulfurization *** developed Ag/SLDH and Pt/SLDH catalysts with abundant heterogeneous interfaces and hierarchical nanostructures demonstrated outstanding oxygen evolution reaction （OER） and hydrogen evolution reaction （HER） performance,achieving low overpotentials of 212 and 35 mV at 10 mA cm-2in 1 M KOH,*** both anode and cathode in water splitting,they required only 1.47 V to reach 10 mA cm-2and exhibited high structural robustness,maintaining stability at 1000 mA cm-2for 300 ***-situ Raman analysis revealed that the synergistic effects of metal nanoparticles and S doping significantly promote the transformation into the S-Co1-xFexOOH layer,which serves as the active phase for water ***,ultraviolet photoelectron spectroscopy （UPS） and density functional theory （DFT） analyses indicated that incorporating metal nanoparticles and S doping increase electron density near the Fermi level and reduce reaction energy barriers,thus enhancing intrinsic OER and HER *** study provides a scalable strategy for synthesizing high-performance electrocatalysts for water splitting,with promising potential for broader applications.

关键词： LDH Spontaneous reaction Metal nanoparticles Water splitting

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

二水平正交饱和设计中零效应搜索法的推广

山西大学学报(自然科学版) 2010年第2期33卷 182-185页

作者：张晓琴赵深淼山西大学数学科学学院

文[5]中提出的零效应搜索法是分析饱和设计的有效方法.一般假定误差是服从正态分布的.零效应搜索法对于密度函数是对称分布的函数也适用,因此零效应搜索法对t分布也适用.由于t分布的密度函数比较复杂,无法给出统计量的具体形式,但可通... 详细信息

文[5]中提出的零效应搜索法是分析饱和设计的有效方法.一般假定误差是服从正态分布的.零效应搜索法对于密度函数是对称分布的函数也适用,因此零效应搜索法对t分布也适用.由于t分布的密度函数比较复杂,无法给出统计量的具体形式,但可通过模拟来实现,通过对各种情况的模拟计算来说明零效应搜索法对t分布也适用.本文选择自由度为3的t分布做模拟.并且在此假定下,也能很好的识别饱和设计中的显著因子,误差方差的估计也很好.

关键词：正交饱和设计次序统计量零效应搜索法显著效应 t分布

Reduced mesencephalic astrocyte-derived neurotrophic factor expression by mutant androgen receptor contributes to neurodegeneration in a model of spinal and bulbar muscular atrophy pathology

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第9期20卷 2655-2666页

作者： Yiyang qin Wenzhen Zhu Tingting Guo Yiran Zhang Tingting Xing Peng Yin Shihua Li xiao-Jiang Li Su Yang Guangdong Key Laboratory of Non-human Primate Research Key Laboratory of CNS Regeneration(Ministry of Education)Guangdong–HongKong–Macao Institute of CNS RegenerationJinan UniversityGuangzhouGuangdong ProvinceChina

Spinal and bulbar muscular atrophy is a neurodegenerative disease caused by extended CAG trinucleotide repeats in the androgen receptor gene,which encodes a ligand-dependent transcription facto *** mutant androgen receptor protein,characterized by polyglutamine expansion,is prone to misfolding and forms aggregates in both the nucleus and cytoplasm in the brain in spinal and bulbar muscular atrophy *** aggregates alter protein-protein interactions and compromise transcriptional *** this study,we reported that in both cultured N2a cells and mouse brain,mutant androgen receptor with polyglutamine expansion causes reduced expression of mesencephalic astrocyte-de rived neurotrophic *** n of mesencephalic astrocyte-derived neurotrophic factor amelio rated the neurotoxicity of mutant androgen receptor through the inhibition of mutant androgen receptor *** down endogenous mesencephalic astrocyte-derived neurotrophic factor in the mouse brain exacerbated neuronal damage and mutant androgen receptor *** findings suggest that inhibition of mesencephalic astrocyte-derived neurotrophic factor expression by mutant androgen receptor is a potential mechanism underlying neurodegeneration in spinal and bulbar muscular atrophy.

关键词： androgen receptor mesencephalic astrocyte-derived neurotrophic factor mouse model neurodegeneration neuronal loss neurotrophic factor polyglutamine disease protein misfolding spinal and bulbar muscular atrophy transcription factor

维普期刊数据库

Zwitterionic hyaluronic acid derivatives for co-delivery of both chemotherapeutic and nucleic acid drugs in breast cancer treatment

在线全文

学校读者我要写书评

暂无评论

Nano Research 2025年第1期18卷 607-617页

作者： Ruo-Lin Jiang Hui-Na Liu Yu-Fan Yang Zhi-Cheng Zhang Qi Dai xiao-Yan Bao Lin-Jie Wu Ya-Xin qin Xin Tan xiao-Yan Sun Xu-Fang Ying Zhi-qing Ben Min Han Institute of Pharmaceutics College of Pharmaceutical SciencesZhejiang UniversityHangzhou 310058China Department of Radiation Oncology Key Laboratory of Cancer Prevention and InterventionThe Second Affiliated HospitalCollege of MedicineZhejiang UniversityHangzhou 310058China Hangzhou Institute of Innovative Medicine Zhejiang UniversityHangzhou 310058China Jinhua Institute of Zhejiang University Jinhua 321299China National Key Laboratory of Advanced Drug Delivery and Release Systems Zhejiang UniversityHangzhou 310058China Polytechnic institute Zhejiang UniversityHangzhou 310015China

Traditionally,hyaluronic acid has been widely used for drug delivery,but the current application bottleneck is that hyaluronic acid is hydrophilic and electronegative,which makes it difficult to carry hydrophobic drugs and small interfering RNA(siRNA)with the same *** on previous studies,we designed and synthesized hyaluronic acid nanocarriers HA-spermine/N,N,N-trimethylcystamine/DOX-TPP(HSTD)for loading siRNA to overcome the problem of siRNA release caused by strong electrostatic ***,N,N,Ntrimethylcystamine in the carrier can be degraded by intracellular glutathione to completely and rapidly release siRNA,thus promoting ***,when codelivered with the chemotherapy drug doxorubicin(DOX),this novel nanocarrier showed promising synergy in inhibiting tumor growth.

关键词： zwitterionic hyaluronic acid N N N-trimethylcystamine small interfering RNA(siRNA) doxorubicin

Proteomic Analysis of Physcomitrella patens under Cold Stress

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Proteomic Analysis of Physcomitrella patens under Cold Stres...

High-mobility group box 1 protein and its role in severe acute pancreatitis

首届全国蛋白质组学学术研讨会

作者： Wang xiao-qin shen Shi-hua He Yi-kun Kuang Ting-yun (College of Life science, Capital Nonnal University, Beijing, P. R. China, 100037 Key Laboratory of Photosynthesis and Environmental Molecular Physiology, Institute of Botany, CAS, Beijing, P. R. China,100093.)

The moss Physcomitrella patens is an attractive model to unravel plant gene functions. In contrast to seed plant, a very efficient homologous recombination system allows routine production of targeted gene knockout. P. patens widely spread in cold temperate zones of the world and could tolerant freezing stress. It has been well established in higher plants that freezing tolerance is acquired by exposure to non-freezing low temperatures. However, little is known about the physiological changes induced by cold acclimation in non-vascular plants such as bryophytes. Here, we present our findings on the proteomic analysis of low temperature treatment on the gametophore of the moss P. patens.

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2015年第5期21卷 1424-1435页

作者： xiao shen Wei-qin Li Department of General Surgery Jinling HospitalMedical School of Nanjing University

The high mobility group box 1(HMGB1),which belongs to the subfamily of HMG-1/-2,is a highly conserved single peptide chain consisting of 215 amino acid residues with a molecular weight of approximately 24894 ***1 is a ubiquitous nuclear protein in mammals and plays a vital role in inflammatory *** pancreatitis is one of the most common causes of acute abdominal pain with a poor *** pancreatitis is an acute inflammatory process of the pancreas(duration of less than six months),for which the severe form is called severe acute pancreatitis(SAP).More and more studies have shown that HMGB1 has a bidirectional effect in the pathogenesis of *** HMGB1 can aggravate the pancreatic inflammatory process,whereas intracellular HMGB1 has a protective effect against *** mechanism of HMGB1 is multiple,mainly through the nuclear factor-κB *** for advanced glycation endproducts and toll-like receptors(TLR),especially TLR-2 and TLR-4,are two major types of receptors mediating the inflammatory process triggered by HMGB1 and may be also the main mediators in the pathogenesis of ***1 inhibitors,such as ethyl pyruvate,pyrrolidine dithiocarbamate and Scolopendra subspinipes mutilans,can decrease the level of extracellular HMGB1 and are the promising targets in the treatment of SAP.

关键词： High mobility group box 1 protein Inhibitors Infla