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Features of the new climate normal 1991-2020 and possible influences on climate monitoring and prediction in China

Advances in Climate Change Research 2023年第6期14卷 930-940页

作者： xiao-juan wang Ya TUO xiao-Fan LI Guo-Lin FENG College of Electronic and Information Engineering Changshu Institute of TechnologySuzhou 215100China Deparment of Amospheric and Oceanic Sciences&Institute of Atmospheric Sciences Fudan UniversityShanghai 200433China Hebei Climate Center/China Meteorological Administration Xiong'an Atmospheric Boundary Layer Key Laboratory/Key Laboratory of Meteorology and Ecological Environment of Hebei Province Shijiazhuang 050021China Laboratory for Climate Studies National Climate Research Center China Meteorological AdministrationBeijing 10o081China

An update on the climate norms each decade is recommended by the World Meteorological Organization(WMO)partly to keep pace with conditions as climate changes over *** accordance with such update,this study documents the features of the new climate normal defined for 1991-2020 and its impacts on climate monitoring and prediction in *** on-site observation and model prediction datasets,our analysis reveals that the new normal of national average precipitation of China during winter and summer is respectively 3.0 and 10.8 mm higher than that of the period *** a result,precipitation observations during 1961-2020 consistently fall below the new *** adjustment of thresholds for precipitation extremes with new climate normals results in a decrease of extreme precipitation occurrence by 0.2-0.8 d on average over the winter and summer seasons during ***,the application of new climate normals induces more pronounced negative temperature anomalies across most areas of *** adjustments of extreme temperature thresholds have led to an increased occurrence of extremely cold days by 1-2 d on average over 1961-2020,while the frequency of extremely hot days decreases by more than 1.4 ***,it is implied that with the development of global warming,the baselines for temperature and precipitation are *** application of the new climate normal may result in the omission of relative threshold based extreme events,promoting increased focus on climate risk reduction ***,the average anomaly sign consistency rates(Pcs)of precipitation and temperature anomaly predictions,relative to the new normal and produced by the Beijing Climate Center,are consistently lower than those relative to the old *** decrease in Pcs implies new challenges for climate prediction,especially for temperature prediction.

关键词： Climate normal Temperature Precipitation Extreme climate event Prediction

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Ovarian mucinous tumor with mural nodules of anaplastic carcinoma:Three case reports

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World Journal of Clinical Cases 2022年第21期10卷 7459-7466页

作者： xiao-juan wang Chun-Yan wang Yan-Feng Xi Peng Bu Pei wang Department of Pathology Shanxi Cancer Hospital and InstituteTaiyuan 030013Shanxi ProvinceChina Department of Molecular Biology Department of Blood TransfusionShanxi Cancer Hospital and InstituteTaiyuan 030013Shanxi ProvinceChina Department of Gynecology Shanxi Cancer Hospital and InstituteTaiyuan 030013Shanxi ProvinceChina

BACKGROUND Anaplastic carcinoma mural nodules in ovarian mucinous tumors are very *** study aimed to report the morphological characteristics,molecular detection results,clinical treatment and prognosis of three ovarian mucinous tumors with mural nodules of anaplastic *** SUMMARY The pathomorphological features,molecular detection results,clinical treatment and prognosis of anaplastic carcinoma mural nodules were described in three *** case 1,sarcoma-like mural nodules(SLMNs)coexisted with anaplastic carcinoma mural *** mutation was found in mucinous *** mutation was found in anaplastic carcinoma nodules and heterotypic cells were found in *** case 2,KRAS mutation occurred in the mucinous epithelium and BRAF mutation occurred in mural *** case 3,both mural nodules and mucinous tumors had the same KRAS mutation and a morphological transition between them was *** three patients died within 2 years,whether receiving chemotherapy or *** Anaplastic carcinoma mural nodules may develop from dedifferentiation of mucinous tumors or are unrelated to mucinous tumors.

关键词： Anaplastic carcinoma BRAF KRAS Mucinous tumor Mural nodules Case report

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Analysis of overload-based cascading failure in multilayer spatial networks

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Chinese Physics B 2020年第9期29卷 404-414页

作者： Min Zhang xiao-juan wang Lei Ji Mei Song Zhong-Hua Liao School of Science Beijing University of Posts and TelecommunicationsBeijing 100876China School of Electronic Engineering Beijing University of Posts and TelecommunicationsBeijing 100876China Beijing Complex Product Advanced Manufacturing Engineering Research Center Beijing Simulation CenterBeijing 100854China State Key Laboratory of Intelligent Manufacturing System Technology Beijing Institute of Electronic System EngineeringBeijing 100854China

Many complex networks in real life are embedded in space and most infrastructure networks are interdependent,such as the power system and the transport *** this paper,we construct two cascading failure models on the multilayer spatial *** our research,the distance l between nodes within the layer obeys the exponential distribution P(l)~exp(-l/ζ),and the length r of dependency link between layers is defined according to node *** entropy approach is applied to analyze the spatial network structure and reflect the difference degree between *** metrics,namely dynamic network size and dynamic network entropy,are proposed to evaluate the spatial network robustness and *** the cascading failure process,the spatial network evolution is analyzed,and the numbers of failure nodes caused by different reasons are also counted,***,we discuss the factors affecting network *** demonstrate that the larger the values of average degree,the stronger the network *** the length r decreases,the network performs *** the probability p is small,asζdecreases,the network robustness becomes more *** p is large,the network robustness manifests better performance asζ*** results provide insight into enhancing the robustness,maintaining the stability,and adjusting the difference degree between nodes of the embedded spatiality systems.

关键词： cascading failure multilayer network load distribution spatial network entropy

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The bothersomeness of female urinary incontinence and its influencing factors: Study from a Chinese city

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International Journal of Nursing Sciences 2014年第1期1卷 58-63页

作者： xiao-juan Wan Jing-Jing Li xiao-juan wang Yu Zhang Yan Liu Chen Wu Ke-Fang wang School of Nursing Shandong UniversityJinanChina School of Nursing Jilin Medical CollegeJilinChina School of Nursing Binzhou Medical CollegeBinzhouChina

Purpose:To investigate the bothersomeness of female urinary incontinence(UI)and analyse its influencing ***:A purposive sample of 506 women with UI from three communities in Jinan was studied using the International Consultation on Incontinence QuestionnaireeUrinary Incontinence Short Form,modified Social Impact Scale,and a coping efficacy *** influencing factors of bothersomeness were identified using one-way analysis of variance,χ^(2) test,and logistic ***:Of the participants,33.4%were bothered byUI symptoms;logistic regression indicated that severity of UI,stigma,coping efficacy,and duration of symptoms were independent factors of bothersomeness,which clarified 49.8%of the ***:UI patients should receive individualised *** workers can provide targeted intervention to patients bothered by UI to alleviate symptoms,decrease the senseof stigma,andincreaseconfidence incopingwithsymptomstodecrease bothersomeness.

关键词： Coping efficacy Female Urinary incontinence Shame

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Clinical characteristics of acute non-varicose upper gastrointestinal bleeding and the effect of endoscopic hemostasis

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World Journal of Clinical Cases 2024年第9期12卷 1597-1605页

作者： xiao-juan wang Yu-Peng Shi Li wang Ya-Ni Li Li-juan Xu Yue Zhang Shuang Han Department of Gastroenterology Honghui Hospital Affiliated to Medicine College of Xi’an Jiaotong UniversityXi'an 710054Shaanxi ProvinceChina

BACKGROUND Acute non-variceal upper gastrointestinal bleeding(ANVUGIB)constitutes a prevalent emergency within Gastroenterology,encompassing 80%-90%of all gastrointestinal hemorrhage *** condition is distinguished by its abrupt onset,swift progression,and notably elevated mortality *** To gather clinical data from patients with ANVUGIB at our hospital in order to elucidate the clinical characteristics specific to our institution and analyze the therapeutic effectiveness of endoscopic *** We retrospectively retrieved the records of 532 patients diagnosed with ANVUGIB by endoscopy at our hospital between March 2021 and March 2023,utilizing our medical record *** pertaining to general patient information,etiological factors,disease outcomes,and other relevant variables were meticulously collected and *** Among the 532 patients diagnosed with ANVUGIB,the male-to-female ratio was 2.91:1,with a higher prevalence among ***,43.6%of patients presented with black stool as their primary complaint,while 27.4%had hematemesis as their initial *** admission,17%of patients exhibited both hematemesis and black stool,while most ANVUGIB patients primarily complained of overt gastrointestinal *** routine blood examinations at admission revealed that 75.8%of patients had anemia,with 63.4%experiencing moderate to severe anemia,and 1.5%having extremely severe anemia(hemoglobin<30 g/L).With regard to etiology,53.2%of patients experienced bleeding without a definitive trigger,24.2%had a history of using gastric mucosa-irritating medications,24.2%developed bleeding after alcohol consumption,2.8%attributed it to improper diet,1.7%to emotional excitement,and 2.3%to fatigue preceding the bleeding ***-induced ANVUGIB was more prevalent in the elderly than middle-aged and young individuals,while bleeding due to alcohol consumption showed the opposite ***,diet-related bleeding was more common

关键词： Acute non-varicose upper gastrointestinal bleeding Clinical characteristics Cause of disease Endoscopic homeostatic therapy

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Panax japonicus and chikusetsusaponins: A review of diverse biological activities and pharmacology mechanism

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Chinese Herbal Medicines 2021年第1期13卷 64-77页

作者： xiao-juan wang Qian Xi Yang Liu Sai Jiang Wei Li Bin Li Wei wang Chang-xiao Liu Hunan Food and Drug Vocational College Changsha 410208China TCM and Ethnomedicine Innovation&Development International Laboratory Innovative Drug Research InstituteSino-Pakistan TCM&Ethnomedicine Research International Cooperation Base(Hunan Province)School of PharmacyHunan University of Chinese MedicineChangsha 410208China Tianjin Institute of Pharmaceutical Research Tianjin 300193China

Panax japonicus, which in the Tujia dialect is known as "Baisan Qi" and "Zhujieshen", is a classic "qi" drug of Tujia ethnomedicine and it has unique effects on disease caused by "qi" stagnation and blood *** paper serves as the basis of further scientific research and development of Panax japonicus. The pharmacology effects of molecular pharmacology were discussed and summarized. P. japonicus plays an important role on several diseases, such as rheumatic arthritis, cancer, cardiovascular agents, and this review provides new insights into P. japonicus as promising agents to substitute ginseng and notoginseng.

关键词： chikusetsusaponin ginsenoside Panax ginseng C.A.Mey Panax japonicas(T.Nees)C.A.Meyer Panax notoginseng(Burk.)F.H.Chen

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Electronic Structure and Chemical Bond of Titanium Diboride

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Journal of Wuhan University of Technology(Materials Science) 2003年第2期18卷 11-14页

作者：闵新民 Wuhan University of Technology

Titanium diboride was calculated by the density function and discrete variational (DFT-DVM) method to study the relation between structure and *** and its first-nearest boron atoms form a strong covalent bond,so TiB 2 has high melting point,hardness and chemical *** atom releases two electrons to form Ti 2+ ions,and a boron atom gets one electron to come into B- ion.B- takes the sp2 hybrid and forms σ bonds to link other boron atoms in the same *** other one 2p z orbital of every B- ion in the same layer interacts each other to form the π molecular orbital,so TiB 2 has fine electrical *** calculated density of state is close to the result of XPS experiment of TiB *** Ti3d and B2p atomic orbitals contribute the total DOS near the Fermi level.

关键词： titanium diboride property calculation electronic structure chemical bond

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Clinical and genetic features of Kenny-Caffey syndrome type 2 with multiple electrolyte disturbances:A case report

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World Journal of Clinical Cases 2023年第10期11卷 2290-2300页

作者： Ning Yuan Lin Lu xiao-Ping Xing Ou wang Yue Jiang Ji Wu Ming-Hai He xiao-juan wang Le-Wei Cao Department of Endocrinology Nanchong Central HospitalThe Second Clinical CollegeNorth Sichuan Medical CollegeNanchong 637000Sichuan ProvinceChina Department of Endocrinology Key Laboratory of National health commissionPeking Union Medical College HospitalPeking Union Medical CollegeChinese Academy of Medical ScienceBeijing 100730China Department of Urology Nanchong Central HospitalThe Second Clinical CollegeNorth Sichuan Medical CollegeNanchong 637000Sichuan ProvinceChina

BACKGROUND Hypoparathyroidism,which can be sporadic or a component of an inherited syndrome,is the most common cause of *** hypocalcemia is accompanied by other electrolyte disturbances,such as hypokalemia and hypomagnesemia,then the cause,such as renal tubular disease,should be carefully *** SUMMARY An 18-year-old female visited our clinic because of short stature and facial deformities,including typical phenotypes,such as low ear position,depression of the nasal bridge,small hands and feet,and loss of *** lab results suggested normal parathyroid hormone but *** addition,multiple electrolyte disturbances were found,including hypokalemia,hypocalcemia and *** physical signs showed a short fourth metatarsal bone of both *** X-ray images showed cortical thickening of long bones and narrowing of the medulla of the *** computed tomography indicated calcification in the bilateral basal ***,the genetic investigation showed a de novo heterogenous mutation of“FAM111A”(c.G1706A:p.R569H).Through a review of previously reported cases,the mutation was found to be the most common mutation site in Kenny-Caffey syndrome type 2(KCS2)cases reported thus far(16/23,69.6%).The mutation was slightly more prevalent in females than in males(11/16,68.8%).Except for hypocalcemia,other clinical manifestations are *** As a rare autosomal dominant genetic disease of hypoparathyroidism,the clinical manifestations of KCS2 are atypical and *** girl presented with short stature,facial deformities and skeletal *** laboratory results revealed hypocalcemia as the main electrolyte *** though her family members showed normal phenotypes,gene detection was performed to find the mutation of the FAM111A gene and confirmed the diagnosis of KCS2.

关键词： Hypocalcemia Hypomagnesemia Hypoparathyroidism Kenny-Caffey syndrome type 2 FAM111A gene Case report

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Residual Dipolar Couplings in Structure Determination of Natural Products

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Natural Products and Bioprospecting 2018年第4期8卷 279-295页

作者： Gao-Wei Li Han Liu Feng Qiu xiao-juan wang Xin-Xiang Lei School of Pharmaceutical Sciences South Central University for NationalitiesWuhan 430074People’s Republic of China College of Chemistry and Chemical Engineering Shangqiu Normal UniversityShangqiu 476000People’s Republic of China

The determination of natural products stereochemistry remains a formidable *** dipolar couplings(RDCs)induced by anisotropic media are a powerful tool for determination of the stereochemistry of organic molecule in *** review will provide a short introduction on RDCs-based methodology for the structural elucidation of natural *** attention is given to the current availability of alignment media in organic *** applications of RDCs for structural analysis of some examples of natural products were discussed and *** Abstract This review provides a short introduction on RDCs-based methodology for the structural elucidation of natural *** attention is given to the current availability of alignment media in organic *** applications of RDCs for structural analysis of some examples of natural products were discussed and summarized.

关键词： spectroscopy Residual dipolar couplings Alignment media Structural elucidation Natural products

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Effect of matrine on transforming growth factor β1 and hepatocyte growth factor in rat liver fibrosis model

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Asian Pacific Journal of Tropical Medicine 2014年第5期7卷 390-393页

作者： Jian-Lan Yu Jun-Hua Li Rong-Gui Cheng Yan-Mei Ma xiao-juan wang Jing-Chun Liu Heji Hospital affiliated to Changzhi Medical School Tumor Hospital of Shanxi Province Shanxi Medical School The First Clinical Hospital of Shanxi Medical School

Objective:To observe the preventive and control effect of matrine on transforming growth factor(TCF- β1) and *** factor(HCF) of liver fibrosis tissue in ***:A total of48 SD rats were randomly divided into A,B,C,D groups with 12 in each,group A as the normal control group and groups B.C,D as liver fibrosis models using composite modulus method with carbon tetrachloride(CCL_4).Group B was the model group,group C adopted γ— interferon lavage therapy in the second day of modeling,and group D adopted matrine lavage treatment,at 4 and8 weeks after *** rats were executed for detection of TGF- β1 and HGF,liver tissue histology and comparison fibrosis degree changes of rat liver tissue between ***:Croups B,C,D showed a more significantly increased TCF- β1 at each time point compared with group A(P<0.05);Group B showed a more significantly increased TGF- β1 than groups C and D at weeks 4 and 8(P<0.05);group D showed a lowest level of TGF-β1,followed by groups C and *** of group B decreased more significantly than A group at weeks 4 and 8(P<0.05);HGF of groups C and D was significantly elevated at 4 and 8 weeks than groups A and B(P<0.05),in which the group D showed the highest level of *** to tissue histologic observation,rat liver tissue structure of group A was clear and normal,tissue structure of group B was destroyed with obvious fibrous tissue hyperplasia and fatty change of hepatic cells;groups C and D showed a slighter liver tissue damage,cell necrosis and connective tissue hyperplasia in collect abbacy than group B with a trend of obvious ***:Matrine can reduce TGF- β1expression and enhance the activity of HGF,so as to realize the inhibition effect on liver fibrosis in rats.

关键词： Liver fibrosis Matrine Transforming growth factor β1 Hepatocyte growth factor

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