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World Journal of Clinical Cases 2024年第1期12卷 188-195页

作者： Shi-Yuan Liu Hao Chen Li-Jia He Chun-Kai Huang Pu wang Zhang-Ru Rui Jue Wu Yang Yuan Yue Zhang Wen-Ju wang xiao-dan wang Central Laboratory Key Laboratory of Tumor Immunological Prevention and Treatment of Yunnan ProvinceYan'an Hospital Affiliated to Kunming Medical UniversityKunming 650051Yunnan ProvinceChina Department of Nephropathy Yan'an Hospital Affiliated to Kunming Medical UniversityKunming 650051Yunnan ProvinceChina

BACKGROUND In this study,we retrospectively analysed macrophage infiltration and podocyte injury in three patients with diffuse proliferative lupus nephritis(LN)who un-derwent repeated renal *** SUMMARY Clinical data of three diffuse proliferative LN patients with different pathological characteristics(case 1 was LN IV-G(A),case 2 was LN IV-G(A)+V,and case 3 was LN IV-G(A)+thrombotic microangiopathy)were *** patients underwent repeated renal biopsies 6 mo later,and renal biopsy specimens were *** infiltration was assessed by CD68 expression detected by immunohistochemical staining,and an immunofluorescence assay was used to detect podocin expression to assess podocyte *** treatment,Case 1 changed to LN III-(A),Case 2 remained as type V LN lesions,and Case 3,which changed to LN IV-S(A),had the worst *** observed reduced macro-phage infiltration after ***,two of the patients with active lesions after treatment still showed macrophage infiltration in the renal *** treatment,the three patients showed discontinuous expression of ***,the integrity of podocin was restored after treatment in Case *** It may be possible to reverse podocyte damage and decrease the infiltrating ma-crophages in LN patients through effective treatment.

关键词： Lupus nephritis Macrophage Podocyte Repeat renal biopsy Thrombotic microangiopathy Case report

Effect of Na^+ on xonotlite crystals in hydrothermal synthesis

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International Journal of Minerals,Metallurgy and Materials 2013年第1期20卷 88-93页

作者： Fei Liu xiao-dan wang Jian-xin Cao School of Chemistry and Chemical Engineering Guizhou University

The effect of Na＋ ion concentration on the crystalline phase composition and morphology of xonotlite crystals pre- pared in a CaO-SiO2-H20 system via hydrothermal synthesis was analyzed. X-ray diffraction （XRD） and scanning electron mi- croscopy （SEM） results indicate that Na＋ ion concentration has a significant impact on the composition and morphology of crystalline phases in the products under the initial conditions of a molar ratio of CaO/SiO2 of 1.0 and a reactant concentration of 0.05 mol.L-1 at 225℃ for 15 h. The main crystalline phase in the products has a phase transition from xonotlite to pectolite, and the morphology changes from fibrous to broomlike shape with the Na＋ ion concentration increasing. Therefore, the content of Na^O in the raw material should be less than 5wt% for preparing pure xonotlite crystals via hydrothermal synthesis in a CaO-SiO2-H20 system.

关键词： crystals xonotlite pectolite hydrothermal synthesis morphology

Construction and Verification of a Simple Smooth Chaotic System

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Communications in Theoretical Physics 2007年第2X期48卷 267-274页

作者： ZHANG xiao-dan SHI Feng wang Zhen School of Applied Science University of Science and Technology Beijing Beijing 100083 China

This article introduces a new chaotic system of three-dimensional quadratic autonomous ordinary differential equations, which can display different attractors with two unstable equilibrium points and four unstable equilibrium points respectively. Dynamical properties of this system are then studied. Furthermore, by applying the undetermined coefficient method, heteroclinic orbit of Shil＇nikov＇s type in this system is found and the convergence of the series expansions of this heteroclinic orbit are proved in this article. The Shil＇nikov＇s theorem guarantees that this system has Smale horseshoes and the horseshoe chaos.

关键词： chaotic attractors three-dimensional quadratic autonomous dynamical system equilibrium point

Hypersingular parameterized Marcinkiewicz integrals with variable kernels on Sobolev and Hardy-Sobolev spaces

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Applied Mathematics(A Journal of Chinese Universities) 2008年第4期23卷 420-430页

作者： CHEN Jie-cheng YU xiao ZHANG Yan-dan wang Hui Department of Mathematics Zhejiang University Hangzhou 310027 China

Let α≥ 0 and 0 〈 ρ ≤ n/2, the boundedness of hypersingular parameterized Marcinkiewicz integrals μΩ,α^ρ with variable kernels on Sobolev spaces Lα^ρ and HardySobolev spaces Hα^ρ is established.

关键词： parameterized Marcinkiewicz integral variable kernel Hardy-Sobolev space L^α-Dini condition

Prediction of cutting power and surface quality, and optimization of cutting parameters using new inference system in high-speed milling process

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Advances in Manufacturing 2021年第3期9卷 388-402页

作者： Long-Hua Xu Chuan-Zhen Huang Jia-Hui Niu Jun wang Han-Lian Liu xiao-dan wang Center for Advanced Jet Engineering Technologies Key Laboratory of High-efficiency and Clean Mechanical Manufacture(Ministry of Education)National Experimental Teaching Demonstration Center for Mechanical Engineering(Shandong University)School of Mechanical EngineeringShandong UniversityJinanPeople’s Republic of China School of Mechanical and Manufacturing Engineering The University of New South Wales(UNSW)SydneyNSW2052Australia Department of Computer Science and Software Engineering Xi’an Jiaotong-Liverpool UniversitySuzhou215123JiangsuPeople’s Republic of China

During the actual high-speed machining process,it is necessary to reduce the energy consumption and improve the machined surface ***,the appropriate prediction models and optimal cutting parameters are difficult to obtain in complex machining ***,a novel intelligent system is proposed for prediction and optimization.A novel adaptive neuro-fuzzy inference system(NANFIS)is proposed to predict the energy consumption and surface *** the NANFIS model,the membership functions of the inputs are expanded into:membership superior and membership *** membership functions are varied based on the machining *** inputs of the NANFIS model are cutting parameters,and the outputs are the machining *** optimization,the optimal cutting parameters are obtained using the improved particle swarm optimization(IPSO)algorithm and NANFIS ***,the IPSO algorithm as a learning algorithm is used to train the NANFIS *** proposed intelligent system is applied to the high-speed milling process of compacted graphite *** experimental results show that the predictions of energy consumption and surface roughness by adopting the NANFIS models are up to 91.2%and 93.4%,*** NANFIS models can predict the energy consumption and surface roughness more accurately compared with other intelligent *** on the IPSO algorithm and NANFIS models,the optimal cutting parameters are obtained and validated to reduce both the cutting power and surface roughness and improve the milling *** is demonstrated that the proposed intelligent system is applicable to actual high-speed milling processes,thereby enabling sustainable and intelligent manufacturing.

关键词： Novel adaptive neuro-fuzzy inference system(NANFIS)model Improved particle swarm optimization(IPSO)algorithm Energy consumption Surface roughness Multiobjective optimization

On the Factors Influencing the High Stretch-Flangeability of a Low-Density 1180 MPa Fe-Mn-Al-C-Nbδ-QP Steel

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Acta Metallurgica Sinica(English Letters) 2024年第8期37卷 1291-1300页

作者： dan‑dan Cui Peng Chen Peng‑Fei wang xiao‑Wu Li Department of Materials Physics and Chemistry School of Materials Science and Engineeringand Key Laboratory for Anisotropy and Texture of Materials(Ministry of Education)Northeastern UniversityShenyang 110819China State Key Laboratory of Rolling and Automation Northeastern UniversityShenyang 110819China

Low-densityδ-quenching and partitioning(δ-QP)steels with excellent strength and ductility have been recently ***,there are still rare reports on the formability of δ-QP steels,which are critical for satisfying the manufacture of structural parts during the application in automotive *** the present work,an 1180 MPa Fe–Mn–Al–C–Nbδ-QP steel with a high ductility was adopted for the stretch–flangeability ***δ-QP steel was developed by separated quenching and partitioning processes.A good hole expansion ratio(HER)of 34.9±0.9%was obtained in the quenched steel,but it has been further increased to 52.2%by the tempering *** improved stretch–flangeability was attributed to the enhanced austenite stability and deformation *** the one hand,the stability of austenite was increased by carbon partitioning during tempering,which reduced crack possibility via the suppression of the fresh martensite *** the other hand,the tempering treatment released the internal stress caused by martensitic transformation and reduced the difference in strength among different phases,resulting in an increase in the resistance to crack initiation and propagation.

关键词： Hole expansion ratio Low-densityδ-quenching and partitioning(δ-QP)steel Stretch-flangeability Austenite stability Deformation uniformity

Odorant receptor orthologues from moths display conserved responses to cis-jasmone

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Insect Science 2024年第4期31卷 1107-1120页

作者： xiao-Qing Hou Zhongqiang Jia dan-dan Zhang Guirong wang Shenzhen Branch Guangdong Laboratory for Lingnan Modern AgricultureSynthetic Biology Laboratory of the Ministry of Agriculture and Rural AffairsAgricultural Genomics Institute at ShenzhenChinese Academy of Agricultural SciencesShenzhenGuangdong ProvinceChina State Key Laboratory for Biology of Plant Diseases and Insect Pests Institute of Plant ProtectionChinese Academy of Agricultural SciencesBeijingChina Department of Biology Lund UniversityLundSweden

In insects,the odorant receptor(OR)multigene family evolves by the birth-and-death evolutionary model,according to which the OR repertoire of each species has undergone specific gene gains and losses depending on their chemical environment,resulting in taxon-specific OR lineage radiations with different sizes in the phylogenetic *** the general divergence in the gene family across different insect orders,the ORs in moths seem to be genetically conserved across species,clustered into 23 major clades containing multiple orthologous groups with single-copy gene from each *** hypothesized that ORs in these orthologous groups are tuned to ecologically important compounds and functionally ***-Jasmone is one of the compounds that not only primes the plant defense of neighboring receiver plants,but also functions as a behavior regulator to various *** test our hypothesis,using Xenopus oocyte recordings,we functionally assayed the orthologues of BmorOR56,which has been characterized as a specific receptor for *** results showed highly conserved response specificity of the BmorOR56 orthologues,with all receptors within this group exclusively responding to *** is supported by the dN/dS analysis,showing that strong purifying selection is acting on this ***,molecular docking showed that the ligand binding pockets of BmorOR56 orthologues to cis-jasmone are *** together,our results suggest the high conservation of OR for ecologically important compounds across Heterocera.

关键词： cis-jasmone evolutionary conservation functional characterization molec-ular docking moths purifying selection

Laser manufacturing of spatial resolution approaching quantum limit

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Light(Science & Applications) 2024年第3期13卷 421-428页

作者： xiao-Jie wang Hong-Hua Fang Zhen-Ze Li dan wang Hong-Bo Sun State Key Laboratory of Precision Measurement Technology and Instruments Department of Precision InstrumentTsinghua UniversityBeijing 100084China State Key Laboratory of Integrated Optoelectronics College of Electronic Science and EngineeringJilin University2699 Qianjin StreetChangchun 130012China

Atomic and close-to-atom scale manufacturing is a promising avenue toward single-photon emitters,single-electron transistors,single-atom memory,and quantum-bit devices for future communication,computation,and sensing *** manufacturing is outstanding to this end for ease of beam manipulation,batch production,and no requirement for *** is,however,suffering from optical diffraction ***,we report a spatial resolution improved to the quantum limit by exploiting a threshold tracing and lock-in method,whereby the two-order gap between atomic point defect complexes and optical diffraction limit is surpassed,and a feature size of<5 nm is *** underlying physics is that the uncertainty of local atom thermal motion dominates electron excitation,rather than the power density slope of the incident *** show that the colour centre yield in hexagonal boron nitride is transformed from stochastic to deterministic,and the emission from individual sites becomes polychromatic to *** a result,single colour centres in the regular array are deterministically created with a unity yield and high positional accuracy,serving as a step forward for integrated quantum technological applications.

关键词： quantum limit resolution

Balanced Polysulfide Containment and Lithium Ion Transport in Lithium-Sulfur Batteries via Nitrogen-doped Carbon Hollow Multi-shelled Structures on Modified Separators

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Chemical Research in Chinese Universities 2024年第4期40卷 690-698页

作者： RAO Fu xiao Qian WEI Yanze wang Jiangyan YU Ranbo wang dan State Key Laboratory of Biochemical Engineering Institute of Process EngineeringChinese Academy of SciencesBeijing100190P.R.China Key Laboratory of Biopharmaceutical Preparation and Delivery Chinese Academy of SciencesBeijing100190P.R.China University of Chinese Academy of Sciences Beijing100049P.R.China Department of Physical Chemistry School of Metallurgical and Ecological EngineeringUniversity of Science&Technology BeijingBeijing100083P.R.China

Representing the next-generation technology in lithium-ion batteries,lithium-sulfur(Li-S)batteries offer increased specific energy without relying on scarce metals like nickel and cobalt,but suffer from a low practical specific energy due to poor conductivity and a short lifespan due to the shuttle effect of *** the confinement of polysulfides and the transport of lithium ions requires highly elaborate modifiers for *** multi-shelled structures(HoMSs)show promise as hierarchical mesostructures for separators,offering multiple shell layers and internal cavities that effectively inhibit polysulfide *** design of these structures is crucial to address these challenges *** this study,nitrogen-doped carbon HoMS(NC HoMS)was created using polymer templates through a precisely controlled polymerization *** featuring NC HoMS-modified separators exhibit improved capacity and cycling stability in comparison to those utilizing commercial ***,triple-shelled NC HoMS strikes a balance in polysulfide containment and lithium ion *** a sulfur loading of 6.34 mg/cm^(2),the Li-S battery can consistently complete 100 charge-discharge cycles,starting with a discharge capacity of 966.4 mA·h/g with a 75.8%capacity retention *** HoMS holds potential as the separator modifier in addressing the polysulfide shuttle problem and facilitating the Li-ion transportation for advanced Li-S batteries.

关键词： Hollow multi-shelled structure Carbon material Li-S battery Separator modification Shuttle effect

Relationship of Retinal Nerve Fiber Layer Thickness and Retinal Vessel Calibers with Cognitive Impairment in the Asymptomatic Polyvascular Abnormalities Population

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Biomedical and Environmental Sciences 2024年第2期37卷 196-203页

作者： wang dan dan wang An Xin ZHANG xiao Li WEI Wen Bin WU Shou Ling ZHAO Xing Quan Department of Neurology Beijing Tiantan HospitalCapital Medical UniversityBeijing 100070China China National Clinical Research Center for Neurological Diseases Beijing 100070China Beijing Tongren Eye Center Beijing Key Laboratory of Ophthalmology and Visual ScienceBeijing Tongren HospitalCapital Medical UniversityBeijing 100005China Department of Cardiology Kailuan HospitalTangshan 063001HebeiChina

Objective Cognitive impairment(CI)in older individuals has a high morbidity rate worldwide,with poor diagnostic methods and susceptible population *** study aimed to investigate the relationship between different retinal metrics and CI in a particular population,emphasizing polyvascular *** We collected information from the Asymptomatic Polyvascular Abnormalities Community Study on retinal vessel calibers,retinal nerve fiber layer(RNFL)thickness,and cognitive function of 3,785participants,aged 40 years or *** regression was used to analyze the relationship between retinal metrics and cognitive *** stratified by different vascular statuses were also *** RNFL thickness was significantly thinner in the CI group(odds ratio:0.973,95%confidence interval:0.953–0.994).In the subgroup analysis,the difference still existed in the non-intracranial arterial stenosis,non-extracranial carotid arterial stenosis,and peripheral arterial disease subgroups(P<0.05).Conclusion A thin RNFL is associated with CI,especially in people with non-large vessel *** underlying small vessel change in RNFL and CI should be investigated in the future.

关键词： Retinal nerve fiber layer Cognitive impairment Polyvascular abnormality