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Dynamic observation of bone marrow suppression and chromosomal aberrations in patients with acute colchicine poisoning

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World Journal of Emergency Medicine 2022年第2期13卷 130-134页

作者： Yan-qing Liu xiao-xia Lu Kai-xun Hu xiao-bo peng Yun Jiang Li-mei Han Zhi-qiang Ma Ming-fei peng Kun Wan Xi-gang Zhang Ze-wu Qiu Poisoning Treatment Department Department of Hematologythe Fifth Medical Center of Chinese PLA General HospitalBeijing 100039China Academy of Military Medical Sciences Academy of Military SciencesBeijing 100850China

Colchicine is a neutral lipophilic tricyclic alkaloid toxic to human cells containing tubulin,[1-2]and primarily stops the proliferation of active cells in the mitotic metaphase,such as intestinal mucosal cells and hematopoietic *** is widely used in treating gout and familial Mediterranean fever,while it is also used in establishing animal and plant experimental model.[3]In the recent study,treatment of patients affected by coronavirus disease 2019(COVID-19)with colchicine may prove a viable path.[4]The course of colchicine poisoning can be divided into three stages,[5]and most of the patients died in the second stage(2-7 d,the multiple organ injury stage).The cause of death was heart failure[6]and bone marrow hematopoietic failure in the terminal phase.[7]Hematopoiesis is a classic sign of colchicine *** cases of colchicine poisoning have been comprehensively reported,and the target organs included heart,digestive tract,muscle,lung,kidney,hematopoietic system,etc.[8-11]This study aimed to investigate the injury of bone marrow hematopoietic system after colchicine poisoning and evaluate the therapeutic effect of bone marrow hematopoietic stimulation drugs.

关键词： establishing neutral alkaloid

Twelve family members with tetramine poisoning after consumption of vegetables grown in polluted soils

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World Journal of Emergency Medicine 2023年第3期14卷 250-252页

作者： Yan-qing Liu xiao-xia Lu Chun-yan Wang Ming-fei peng xiao-bo peng Yun Jiang Le-xin Zheng Dan-dan Yuan Xi-gang Zhang Ze-wu Qiu Poisoning Treatment Department Senior Department of Hepatologythe Fifth Medical Center of PLA General HospitalBeijing 100071China

The main toxic component of tetramine is tetramethylenedisulfotetramine(TETS).It is a sulfonamide derivative without special antidote,tasteless and tasteless,with high toxicity and high mortality.[1]It was first discovered by a German scientist Hagen in *** its use has been banned worldwide due to its high toxicity and mortality rate,it is still available in certain countries and has led to cases of intentional and unintentional *** blocksγ-neurons,leading to dizziness,fatigue,nausea,vomiting,convulsions,and other symptoms.[2-4]Due to the lack of recognized effective antidotes,many poisoned people suff ocate and die as a result of continuous spasms of the respiratory muscles.[5-7]Tetramine poisoning sometimes occurs,but it is rare for vegetables grown in tetraminecontaminated soil to cause group poisoning after being eaten.

关键词： mortality poisoning vegetables

Chlorine poisoning caused by improper mixing of household disinfectants during the COVID-19 pandemic:Case series

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World Journal of Clinical Cases 2022年第25期10卷 8872-8879页

作者： Guo-Dong Lin Jie-Yi Wu xiao-bo peng xiao-Xia Lu Zhong-Ying Liu Zhi-Guo Pan Ze-Wu Qiu Jian-Guang Dong Department of Critical Care Medicine General Hospital of Southern Theater Command of PLAGuangzhou 510010Guangdong ProvinceChina Senior Department of Hematology The Fifth Medical Center of PLA General HospitalBeijing 100071China

BACKGROUND Misuse of disinfectants during the coronavirus disease 2019 pandemic has led to several poisoning ***,there are few clinical case reports on poisoning caused by improper mixing of household *** To summarize the clinical characteristics and treatment effects of chlorine poisoning caused by improper mixing of hypochlorite bleach with acidic cleaning *** We retrospectively analyzed baseline and clinical data,clinical symptoms,and treatment methods of seven patients with chlorine poisoning who were admitted to the National Army Poisoning Treatment *** Among the seven patients,the average poisoning time(exposure to admission)was 57 h(4-240 h).All patients were involved in cleaning *** computed tomography scans revealed bilateral lung effusions or inflammatory changes in five *** partial pressure of oxygen decreased in six patients,and respiratory failure occurred in *** patients had different degrees of increase in white blood cell *** oxygen therapy,non-invasive mechanical ventilation,anti-inflammatory corticosteroids,antioxidants,and antibiotics were administered for *** average length of hospital stay was 7 d(4-9 d).All seven patients recovered and were *** Improper mixing of household disinfectants may cause damage to the respiratory system due to chlorine *** may improve lung exudation in severe cases,and symptomatic supportive treatment should be performed early.

关键词： Hypochlorite bleach Acidic cleaning agents Chlorine poisoning Toxic lung injury Household disinfectant

Treatment of Pulsatile Tinnitus Associated with Multiple Factors

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Chinese Medical Journal 2015年第3期128卷 413-414页

作者： xiao-bo Ma Guo-peng Wang Rong Zeng Shu-Sheng Gong Department of Otolaryngology Head and Neck Surgery Beijing Tongren Hospital Capital Medical University Beijing 100730 China

Numerous factors may lead to pulsatile tinnitus （PT）, including atherosclerosis, benign intracranial hypertension, glomus tympanicum tumor, dural arteriovenous fistulas （dAVFs）, abnormalities of the sigmoid sinus （dehiscence and diverticulum）, and jugular bulb anomalies （glomus jugular tumor, diverticulum, high-riding or dehiscent jugular bulb）. However, exact causes often cannot be found in many patients even after a detailed physical examination and extensive auxiliary examinations. Moreover, no effective treatment is available for these patients. Patients with PT associated with multiple factors are seldom reported, and the condition is essentially intractable. Here, we reported three cases with PT involving multiple factors.

关键词： Dural Arteriovenous Fistulas Jugular Bulb Mastoid Emissary Vein Pulsatile Tinnitus Sigmoid Sinus

Research on in-situ condition preserved coring and testing systems

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Petroleum Science 2021年第6期18卷 1840-1859页

作者： He-Ping Xie Tao Liu Ming-Zhong Gao Ling Chen Hong-Wei Zhou Yang Ju Feng Gao xiao-bo peng Xiong-Jun Li Rui-Dong peng Ya-Nan Gao Cong Li Zhi-Qiang He Ming-Qing Yang Zhi-Yu Zhao Guangdong Provincial Key Laboratory of Deep Earth Sciences and Geothermal Energy Exploitation and Utilization Institute of Deep Earth Sciences and Green EnergyCollege of Civil and Transportation EngineeringShenzhen UniversityShenzhen518060GuangdongChina Shenzhen Key Laboratory of Deep Underground Engineering Sciences and Green Energy Shenzhen UniversityShenzhen518060GuangdongChina MOE Key Laboratory of Deep Earth Science and Engineering College of Water Resource and HydropowerSichuan UniversityChengdu 610065SichuanChina School of Mechanical Engineering Sichuan UniversityChengdu610065SichuanChina Institute of New Energy and Low-Carbon Technology Sichuan UniversityChengdu610065SichuanChina State Key Laboratory of Coal Resources and Safe Mining China University of Mining and Technology(Beijing)Beijing100083China Frontier Science Research Center for Fluidized Mining of Deep Underground Resources China University of Mining and TechnologyXuzhou221116JiangsuChina

As shallow resources are increasingly depleted,the mechanics'theory and testing technology of deep insitu rock has become *** coring technologies obtain rock samples without retaining the in-situ environmental conditions,leading to distortion of the measured ***,a coring and testing systems retaining in-situ geological conditions is presented:the coring system that obtains in-situ rock samples,and the transfer and testing system that stores and analyzes the rocks under a reconstructed *** ICP-Coring system mainly consists of the pressure controller,active insulated core reactor and insulation layer and sealing *** ultimate bearing strength of 100 MPa for pressurepreservation,temperature control accuracy of 0.97%for temperature-retained are ***_(4)and CO permeability of the optimized sealing film are as low as 3.85 and 0.33 ppm/*** average tensile elongation of the film is 152.4%and the light transmittance is reduced to 0%.Additionally,the pressure and steady-state temperature accuracy for reconstructing the in-situ environment of transfer and storage system up to 1%and±0.2 is *** error recorded of the noncontact sensor ring made of lowdensity polymer is less than 6%than that of the contact *** system can provide technical support for the deep in-situ rock mechanics research,improving deep resource acquisition capabilities and further clarifying deep-earth processes.

关键词： Deep mining In-situ environmental conditions In-situ condition preserved coring and testing In-situ transfer Deep-earth processes ICP-Coring In-situ condition-preserved coring

Electrochemical conversion of methane to bridge the gap in the artificial carbon cycle

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Journal of Energy Chemistry 2025年第1期100卷 286-308页

作者： Yuhao peng Yuefeng Song Ihar Razanau Juanxiu xiao Wei xiao Di Hu Guoxiong Wang College of Chemistry and Molecular Sciences Hubei Key Laboratory of Electrochemical Power Sources Wuhan University State Key Laboratory of Catalysis Dalian National Laboratory for Clean Energy iChEM (Collaborative Innovation Center of Chemistry for Energy Materials) Dalian Institute of Chemical Physics Chinese Academy of Sciences Laboratory of Physical-Chemical Technologies SSPA Scientific and Practical Materials Research Centre of NAS of Belarus State Key Laboratory of Marine Resources Utilization in South China Sea Collaborative Innovation Center of Marine Science and Technology School of Marine Science and Engineering Hainan University Department of Chemical and Environmental Engineering University of Nottingham Ningbo China

Methane, an abundant one-carbon（C1） resource, is extensively used in the industrial production of vital fuels and value-added chemicals. However, current industrial methane conversion technologies are energy-and carbon-intensive, mainly due to the high activation energy required to break the inert C–H bond, low selectivity, and problematic side reactions, including CO2emissions and coke deposition. Electrochemical conversion of methane（ECM） using intermittent renewable energy offers an attractive solution, due to its modular reactor design and operational flexibility across a broad spectrum of temperatures and pressures. This review emphasizes conversion pathways of methane in various reaction systems, highlighting the significance and advantages of ECM in facilitating a sustainable artificial carbon cycle. This work provides a comprehensive overview of conventional methane activation mechanisms and delineates the complete pathways of methane conversion in electrolysis contexts. Based on surface/interface chemistry, this work systematically analyzes proposed reaction pathways and corresponding strategies to enhance ECM efficiency towards various target products, including syngas, hydrocarbons, oxygenates, and advanced carbon materials. The discussion also encompasses opportunities and challenges for the ECM process, including insights into ECM pathways, rational electrocatalyst design, establishment of benchmarking protocols, electrolyte engineering, enhancement of CH4conversion rates, and minimization of CO2emission.

关键词： Methane Electrochemical conversion Reaction mechanism Catalyst design Electrode Electrocatalysis

Observation of acoustic hybrid topological phases induced by the p-d orbital interactions

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 132-139页

作者： xiao Xiang Feng Gao Yu-Gui peng peng Wu Zong-Lin Li Xue-Feng Zhu School of Physics and Innovation Institute Huazhong University of Science and Technology

In spinless systems,growing attention has recently been attracted to synthetic gauge fields,which redefine the fundamental crystal symmetries by utilizing the projective algebraic ***,synthetic gauge fields have been commonly investigated in single orbital systems,and explorations on hybrid orbitals remain elusive in ***,we report the experimental observation of hybrid topological phases induced by hybrid synthetic gauge flux,which is formed by the interaction between p and d orbitals embedded in acoustic *** breaking the translation symmetries of Lxand/or Ly,we unambiguously demonstrate the first-order M?bius edge states and higher-order corner *** work establishes a platform for seeking exotic topological phases induced by hybrid-orbitals interactions and initializing the framework of hybrid-orbitalsrelated topological *** applications can be anticipated in scenarios such as high-quality sensing and robust wave trapping due to the stepwise energy distribution of the hybrid topological phase.

关键词： topological insulator synthetic gauge field projective symmetry corner states

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中国民航客运机票定价策略研究

四川大学学报（哲学社会科学版） 2000年第6期 10-15页

作者：肖伯春彭杰美国长岛大学四川大学管理学院硕士研究生四川成都610064

通过分析目前中国民航客运市场的现状 ,针对统一限价政策存在的许多问题和中国加入WTO形势下的新问题 ,对价格体系的科学性和合理性进行探讨 ,并借鉴国外航空公司收益管理的先进理论与方法。

关键词：民航客运收益管理多级票价体系中国机票价格

城市规模异质性与农民工城市就业的替代效应——基于参数和半参数面板数据估计

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经济体制改革 2017年第2期 17-23页

作者：周密赵晓琳屈小博霍鹏沈阳农业大学经济管理学院中国社会科学院人口与劳动经济研究所中国人民大学农业与农村发展学院

本文采用中国综合社会调查2005~2013年数据,根据受教育程度、地区、工作经验和城市规模的差异,构建了一个包含农民工数量和本地市民就业率等变量的面板数据。运用参数和半参数估计方法,揭示出农民工城市进入会降低本地市民就业率,但是... 详细信息

本文采用中国综合社会调查2005~2013年数据,根据受教育程度、地区、工作经验和城市规模的差异,构建了一个包含农民工数量和本地市民就业率等变量的面板数据。运用参数和半参数估计方法,揭示出农民工城市进入会降低本地市民就业率,但是存在城市规模异质性。农民工进入对特大城市本地市民就业率的影响表现出先下降再提高的规律,对大城市本地市民就业的影响表现为先提高后下降再提高的趋势,对中小城市本地市民就业率的影响则表现出先下降再提高再下降的规律。此外,农民工城市进入对本地市民就业率的影响还存在经济发展程度上的异质性,在经济发达地区表现出提升本地市民就业,在经济欠发达地区则表现为降低本地市民就业。

关键词：农民工工资决定城市规模半参数估计