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Efficacy of surgical resection and ultra-reduced tension suture combined with superficial radiation in keloid treatment

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World Journal of Clinical Cases 2023年第35期11卷 8310-8319页

作者： xiao-Ying Hu Qiao Yang xiao-yu guan Jin-Ying Li Ling-Ling Wang Kun Li xiao-Tao Zhang Department of Cosmetic Medicine Qingdao Eighth People’s HospitalQingdao 266100Shandong ProvinceChina Department of Radiation Oncology The Affiliated Qingdao Central Hospital of Qingdao UniversityQingdao 266042Shandong ProvinceChina

BACKGROUND There are many available treatment options for keloid;however,single treatments are usually less ***,more scientifically rational and effective com-bined treatment methods should be sought to solve the pain associated with *** To explore the efficacy and safety of surgical resection and ultra-reduced tension suture combined with superficial radiation as keloid *** Fifteen keloid patients admitted to Qingdao Eighth People's Hospital from June 2020 to January 2022 were enrolled in this retrospective *** patients underwent a comprehensive treatment approach comprising surgical resection,ultra-reduced tension suture incision,and superficial radiation therapy within 24 h *** modified Vancouver Scar Scale(mVSS)and Patient and Observer Scar Assessment Scale(POSAS)were used to evaluate the treatment effect,whereas the efficacy,adverse effects,and recurrence rate were observed according to the 12-mo follow-up after *** The mVSS and POSAS scores at 1 and 6 mo after combination treatment decreased compared to before treatment(P<0.001),and the overall response rate was 93.3%.Only one case recurred,yielding a 6.7%recurrence *** incidence of local chromour sedimentation rate in 1–3 mo after radiotherapy was 33.3%(5 patients),all subsiding after 6–9 mo,without complications,such as delayed wound healing or *** Surgical resection,super subtraction sutures,and superficial radiotherapy are treatment methods with short courses,low recurrence rates,and good safety profiles.

关键词： Keloid Ultrasound suture Radiotherapeutics Superficial radiation Ultra-reduced tension suture Radiation

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Effect of Mn addition on microstructure and mechanical properties of GX40CrNiSi25-12 austenitic heat resistant steel

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China Foundry 2024年第3期21卷 205-212页

作者： guan-yu Jiang Meng-wu Wu xiao-guang Yang Hui Wang yu-yuan Zhu Hubei Key Laboratory of Advanced Technology for Automotive Components Wuhan University of TechnologyWuhan 430070China Hubei Longzhong Laboratory Xiangyang 441000HubeiChina Wescast Industries(China)Co. Ltd.Wuhan 430100China

Three types of steels were designed on the basis of GX40CrNiSi25-12 austenitic heat resistant steel by adding different Mn contents(2wt.%,6wt.%,and 12wt.%).Thermodynamic calculation,microstructure characterization and mechanical property tests were conducted to investigate the effect of Mn addition on the microstructure and mechanical properties of the austenitic heat resistant *** show that the matrix structure in all the three types of steels at room temperature is completely *** NbC and M_(23)C_(6)precipitate at grain boundaries of austenite *** the increase of Mn content,the number of carbides increases and their distribution becomes more *** the Mn content increases from 1.99%to 12.06%,the ultimate tensile strength,yield strength and elongation increase by 14.6%,8.0%and 46.3%,*** improvement of the mechanical properties of austenitic steels can be explained by utilizing classic theories of alloy strengthening,including solid solution strengthening,precipitation strengthening,and grain *** increase in alloy strength can be attributed to solid solution strengthening and precipitation strengthening caused by the addition of *** improvement of the plasticity of austenitic steels can be explained from two aspects:grain refinement and homogenization of precipitated phases.

关键词： austenitic heat resistant steel manganese microstructure mechanical properties

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Roles and application of exosomes in the development,diagnosis and treatment of gastric cancer

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World Journal of Gastrointestinal Oncology 2024年第3期16卷 630-642页

作者： xiao-Li guan xiao-Ying guan Zheng-Yi Zhang Department of General Medicine The Second Hospital of Lanzhou UniversityLanzhou 730030Gansu ProvinceChina Department of Pathology The Second Hospital of Lanzhou UniversityLanzhou 730030Gansu ProvinceChina

As important messengers of intercellular communication,exosomes can regulate local and distant cellular communication by transporting specific exosomal con-tents and can also promote or suppress the development and progression of gas-tric cancer(GC)by regulating the growth and proliferation of tumor cells,the tumor-related immune response and tumor *** transport bioactive molecules including DNA,proteins,and RNA(coding and noncoding)from donor cells to recipient cells,causing reprogramming of the target *** this review,we will describe how exosomes regulate the cellular immune respon-se,tumor angiogenesis,proliferation and metastasis of GC cells,and the role and mechanism of exosome-based therapy in human *** will also discuss the potential application value of exosomes as biomarkers in the diagnosis and treat-ment of GC and their relationship with drug resistance.

关键词： Exosomes Gastric cancer Immune regulation Diagnosis Cancer therapy

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AdaPIP: Adaptive picture-in-picture guidance for 360 ◦ film watching

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Computational Visual Media 2024年第3期10卷 487-503页

作者： Yi-xiao Li guan Luo Yi-Ke Xu yu He Fang-Lue Zhang Song-Hai Zhang Department of Computer Science and Technology Tsinghua UniversityBeijingChinaand Beijing National Research Center for Information Science and Technology(BNRist)Tsinghua UniversityBeijingChina Key Laboratory of Space Utilization Technology and Engineering Center for Space UtilizationChinese Academy of SciencesBeijingChina Victoria University of Wellington WellingtonNew Zealand

360◦videos enable viewers to watch freely from different directions but inevitably prevent them from perceiving all the helpful *** mitigate this problem,picture-in-picture(PIP)guidance was proposed using preview windows to show regions of interest(ROIs)outside the current view *** identify several drawbacks of this representation and propose a new method for 360◦ﬁlm watching called *** enhances traditional PIP by adaptively arranging preview windows with changeable view ranges and *** addition,AdaPIP incorporates the advantage of arrow-based guidance by presenting circular windows with arrows attached to them to help users locate the corresponding ROIs more *** also adapted AdaPIP and Outside-In to HMD-based immersive virtual reality environments to demonstrate the usability of PIP-guided approaches beyond 2D *** user experiments on 2D screens,as well as in VR environments,indicate that AdaPIP is superior to alternative methods in terms of visual experiences while maintaining a comparable degree of immersion.

关键词： 360◦videos picture-in-picture(PIP) virtual reality(VR) visual guidance

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A GMDA clustering algorithm based on evidential reasoning architecture

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Chinese Journal of Aeronautics 2024年第1期37卷 300-311页

作者： Haibin WANG Xin guan xiao YI Shuangming LI Guidong SUN Naval Aviation University Yantai 264001China Unit 92941 of PLA Huludao 125001China Institute of Systems Engineering Beijing 100082China

The traditional clustering algorithm is difficult to deal with the identification and division of uncertain objects distributed in the overlapping region,and aimed at solving this problem,the Evidential Clustering based on General Mixture Decomposition Algorithm(GMDA-EC)is ***,the belief classification of target cluster is carried out,and the sample category of target distribution overlapping region is ***,on the basis of General Mixture Decomposition Algorithm(GMDA)clustering,the fusion model of evidence credibility and evidence relative entropy is constructed to generate the basic probability assignment of the target and achieve the belief division of the ***,the performance of the algorithm is verified by the synthetic dataset and the measured *** experimental results show that the algorithm can reflect the uncertainty of target clustering results more comprehensively than the traditional probabilistic partition clustering algorithm.

关键词： Evidential clustering Credal partition Evidential reasoning Mixed decomposition Gaussian mixture model

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3D Localization for Multiple AUVs in Anchor-Free Environments by Exploring the Use of Depth Information

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IEEE/CAA Journal of Automatica Sinica 2024年第4期11卷 1051-1053页

作者： Yichen Li Wenbin yu Xinping guan the Department of Automation Shanghai Jiao Tong UniversityShanghai 200240 the Key Laboratory of System Control and Information Processing Ministry of Education of ChinaShanghai Jiao Tong UniversityShanghai 200240China

Dear Editor,This letter investigates the cooperative localization problem for multiple autonomous underwater vehicles(AUVs)in underwater anchor-free environments,where AUV localization errors grow without bound due to the accumulated errors in inertial measurements(termed accumulated errors hereafter)and the lack of anchors(with known positions).

关键词： AUVs underwater hereafter

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First-principles study on the diffusion behavior of Cs and I in Cr coating

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Nuclear Science and Techniques 2024年第6期35卷 177-188页

作者： Shu-Ying Lin xiao-Jing Li Lin-Bing Jiang Xi-Jun Wu Hui-Qin Yin yu Ma Wen-guan Liu Sino-French Institute of Nuclear Engineering and Technology Sun Yat-Sen UniversityZhuhai 519082China School of Nuclear Science and Technology University of South ChinaHengyang 421001China

Cs and I can migrate through fuel-cladding interfaces and accelerate the cladding corrosion process induced by the fuel-cladding chemical *** coating has emerged as an important candidate for mitigating this chemical *** this study,first-principles calculations were employed to investigate the diffusion behavior of Cs and I in the Cr bulk and grain boundaries to reveal the microscopic interaction mitigation mechanisms at the fuel-cladding *** interaction between these two fission products and the Cr coating were studied systematically,and the Cs and I temperature-dependent diffusion coefficients in Cr were obtained using Bocquet’s oversized solute-atom model and Le Claire’s nine-frequency model,*** results showed that the Cs and I migration barriers were significantly lower than that of Cr,and the Cs and I diffusion coefficients were more than three orders of magnitude larger than the Cr self-diffusion coefficient within the temperature range of Generation-IV fast reactors(below 1000 K),demonstrating the strong penetration ability of Cs and ***,Cs and I are more likely to diffuse along the grain boundary because of the generally low migration barriers,indicating that the grain boundary serves as a fast diffusion channel for Cs and I.

关键词： First-principles calculation Fuel cladding chemical interaction Cr coating Fission product Diffusion Grain boundary

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Synthesis of amidines via iron-catalyzed dearomative amination of β-naphthols with oxadiazolones

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Organic Chemistry Frontiers 2022年第2期9卷 380-385页

作者： Yan-Hui Fan xiao-yu guan Wen-Pei Li Cheng-Zhou Lin De-Xian Bing Mei-Zhi Sun Guo Cheng Jing Cao Jun-Jie Chen Qing-Hai Deng The Education Ministry Key Lab of Resource Chemistry Joint International Research Laboratory of Resource ChemistryMinistry of EducationShanghai Key Laboratory of Rare Earth Functional Materialsand Shanghai Frontiers Science Center of Biomimetic CatalysisCollege of Chemistry and Materials ScienceShanghai Normal UniversityShanghai 200234China

An iron-catalyzed dearomative amination of β-naphthols via a nitrene-transfer process has been ***,which have rarely been applied for the synthesis of amidines,are used as the nitrene source.A variety of amidines bearing β-naphthalenone moieties were generated smoothly in good to high yields(up to 98%)in the presence of 1.5 equivalents of tetrabutylammonium bromide,which was added as an essential additive.

关键词： catalyzed smoothly additive

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Elastic buckling analysis and optimization of thin-walled bamboo-like pipe beam subjected to pure bending

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Chinese Journal of Aeronautics 2024年第3期37卷 133-152页

作者： Yayun yu Dongli MA Liang ZHANG xiaopeng YANG Hao guan School of Aeronautic Science and Engineering Beihang UniversityBeijing 100191China

In this paper,a stiffening design imitating the bamboo node is proposed for weight reduction of the long composite pipe beam subjected to bending *** distribution of bamboo nodes can efficiently suppress the ovalization of the section,thus significantly improving the bending resistance of the *** on this principle,ring stiffeners are proposed to be fixed to the pipe beam,making the long beam equivalent to the combination of a series of short pipes that suffered less section ovalization.A database of the optimal laminate orientations for different normalized lengths is obtained through optimizations,where the discreteness of the ply count is *** on this database,weight optimizations are conducted,and the optimal designs of beams with and without stiffeners are obtained and *** comparison results show that the proposed bamboo-like stiffened beam not only regains a near-linear load–displacement relationship,but also reduces the weight by up to 16%under the same buckling *** addition,it is found that for the pipe beams with radius-to-thickness ratios of more than 18,increasing the radius leads to a decrease in elastic buckling resistance when the weight remains a constant,which is opposite to the design for strength and *** model and database developed in this paper can provide a reference for weight reduction design and weight estimation for composite pipe beams.

关键词： Composite beam Buckling Thin-walled structure Unmanned aerial vehicles Bamboo

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Deep Learning Blockchain Integration Framework for Ureteropelvic Junction Obstruction Diagnosis Using Ultrasound Images

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Tsinghua Science and Technology 2024年第1期29卷 1-12页

作者： yu guan Pengceng Wen Jianqiang Li Jinli Zhang Xianghui Xie Faculty of Information Technology Beijing University of TechnologyBeijing 100124China Beijing Children’s Hospital Affiliated to Capital Medical University Beijing 100020China

UreteroPelvic Junction Obstruction(UPJO)is a common hydronephrosis disease in children that can result in an even progressive loss of renal *** is an economical,radiationless,noninvasive,and high noise preliminary diagnostic step for *** intelligence has been widely applied to medical fields and can greatly assist doctors'diagnostic *** demand for a highly secure network environment in transferring electronic medical data online,therefore,has led to the development of blockchain *** this study,we built and tested a framework that integrates a deep learning diagnosis model with blockchain *** diagnosis model is a combination of an attention-based pyramid semantic segmentation network and a discrete wavelet transformation-processed residual classification *** also compared the performance between benchmark models and our *** diagnosis model outperformed benchmarks on the segmentation task and classification task with MloU=87.93,MPA=93.52,and accuracy=91.77%.For the blockchain system,we applied the InterPlanetary File System protocol to build a secure and private sharing *** framework can automatically grade the severity of UPJO using ultrasound images,guarantee secure medical data sharing,assist in doctors'diagnostic ability,relieve patients'burden,and provide technical support for future federated learning and linkage of the Internet of Medical Things(loMT).

关键词： data mining image processing and computer vision machine learning medical information systems

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