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Usefulness of interferon-γrelease assay for the diagnosis of sputum smear-negative pulmonary and extra-pulmonary TB in Zhejiang Province,China

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Infectious Diseases of Poverty 2017年第1期6卷 1074-1078页

作者： Lei Ji Yong-Liang Lou Zhong-Xiu Wu Jin-Qin Jiang Xing-Li Fan Li-Fang Wang xiao-xiang liu Peng Du Jie Yan Ai-Hua Sun Department of Basic Medicine Hangzhou Medical CollegeHangzhou 310053ZhejiangPeople’s Republic of China School of Laboratory Medical Science and Life Science Wenzhou Medical UniversityWenzhou 325035ZhejiangPeople’s Republic of China Zhejiang Blood Center Hangzhou 310006ZhejiangPeople’s Republic of China Division of Basic Medical Microbiology State Key Laboratory for Diagnosis and Treatment of Infectious DiseasesFirst Affiliated Hospital of Zhejiang UniversityHangzhou 310003ZhejiangPeople’s Republic of China Department of Medical Microbiology and Parasitology College of MedicineZhejiang UniversityHangzhou 310058ZhejiangPeople’s Republic of China

Background:Quick diagnosis of smear-negative pulmonary tuberculosis(TB)and extra-pulmonary TB are urgently needed in clinical *** research aims to investigate the usefulness of the interferon-γrelease assay(IGRA)for the diagnosis of smear-negative pulmonary and extra-pulmonary ***:We performed TB antibody and TB-IGRA tests on 389 pulmonary TB patients(including 120 smear-positive pulmonary TB patients and 269 smear-negative pulmonary TB patients),113 extra-pulmonary TB patients,81 patients with other pulmonary diseases and 100 healthy *** samples for the TB-Ab test and the TB-IGRA were collected,processed,and interpreted according to the manufacturer’s ***:The detection ratio of smear-positive pulmonary TB patients and smear-negative pulmonary TB patients were 90.8%(109 of 120)and 89.6%(241 of 269),*** was no statistically significant difference of its performance between these two sample sets(P>0.05).The detection ratio of positive TB patients and extra-pulmonary TB patients were 90.0%(350 of 389)and 87.6%(99 of 113),respectively,which was not significantly different(P>0.05).Conclusions:In this work,the total detection ratio using TB-IGRA was 89.4%,therefore TB-IGRA has diagnostic values in smear-negative pulmonary TB and extra-pulmonary TB diagnosis.

关键词： Interferon-gamma release assay Smear-negative pulmonary TB Extra-pulmonary TB

Unlocking the stable interface in aqueous zinc-ion battery with multifunctional xylose-based electrolyte additives

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Journal of Energy Chemistry 2025年第1期100卷 770-778页

作者： xiaoqin Li Jian xiang Lu Qiu xiaohan Chen Yinkun Zhao Yujue Wang Qu Yue Taotao Gao Wenlong liu Dan xiao Zhaoyu Jin Panpan Li Institute for Advanced Study Chengdu University School of Mechanical Engineering Chengdu University College of Food and Biological Engineering Chengdu University Institute of Fundamental and Frontier Sciences University of Electronic Science and Technology of China College of Materials Science and Engineering Sichuan University

The growth of dendrites and the side reactions occurring at the Zn anode pose significant challenges to the commercialization of aqueous Zn-ion batteries（AZIBs）. These challenges arise from the inherent conflict between mass transfer and electrochemical kinetics. In this study, we propose the use of a multifunctional electrolyte additive based on the xylose（Xylo） molecule to address these issues by modulating the solvation structure and electrode/electrolyte interface, thereby stabilizing the Zn anode. The introduction of the additive alters the solvation structure, creating steric hindrance that impedes charge transfer and then reduces electrochemical kinetics. Furthermore, in-situ analyses demonstrate that the reconstructed electrode/electrolyte interface facilitates stable and rapid Zn2+ion migration and suppresses corrosion and hydrogen evolution reactions. As a result, symmetric cells incorporating the Xylo additive exhibit significantly enhanced reversibility during the Zn plating/stripping process, with an impressively long lifespan of up to 1986 h, compared to cells using pure ZnSO4electrolyte. When combined with a polyaniline cathode, the full cells demonstrate improved capacity and long-term cyclic stability. This work offers an effective direction for improving the stability of Zn anode via electrolyte design, as well as highperformance AZIBs.

关键词： Solvation

Observation of acoustic hybrid topological phases induced by the p-d orbital interactions

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 132-139页

作者： xiao xiang Feng Gao Yu-Gui Peng Peng Wu Zong-Lin Li Xue-Feng Zhu School of Physics and Innovation Institute Huazhong University of Science and Technology

In spinless systems,growing attention has recently been attracted to synthetic gauge fields,which redefine the fundamental crystal symmetries by utilizing the projective algebraic ***,synthetic gauge fields have been commonly investigated in single orbital systems,and explorations on hybrid orbitals remain elusive in ***,we report the experimental observation of hybrid topological phases induced by hybrid synthetic gauge flux,which is formed by the interaction between p and d orbitals embedded in acoustic *** breaking the translation symmetries of Lxand/or Ly,we unambiguously demonstrate the first-order M?bius edge states and higher-order corner *** work establishes a platform for seeking exotic topological phases induced by hybrid-orbitals interactions and initializing the framework of hybrid-orbitalsrelated topological *** applications can be anticipated in scenarios such as high-quality sensing and robust wave trapping due to the stepwise energy distribution of the hybrid topological phase.

关键词： topological insulator synthetic gauge field projective symmetry corner states

Carbon-supported CeNCl as an efficient catalyst for CO_(2)cycloaddition

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Nano Research 2025年第1期18卷 157-163页

作者： Li liu Lingling Zhang xiang Chu Baokang Geng Huilin Wang Zongxiang Li xiao Wang Shuyan Song Hongjie Zhang School of Applied Chemistry and Engineering University of Science and Technology of ChinaHefei 230026China State Key Laboratory of Rare Earth Resource Utilization Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022China Sinocare Incorporation Changsha 410221China Department of Chemistry Tsinghua UniversityBeijing 100084China

The cycloaddition reaction of CO_(2)with epoxide not only effectively reduces the concentration of CO_(2)in the atmosphere,but also has excellent industrial application value and up to 100%atom utilization,but there are difficulties in separation and recovery of traditional homogeneous catalysts,harsh reaction conditions of traditional heterogeneous catalysts,and activation of CO_(2)*** this paper,an easily synthesized heterogeneous catalyst CeNCl/C was used to catalyze the cycloaddition reaction of CO_(2)with styrene oxide,with a high yield of 92.7%,a high selectivity of 96.7%,a turnover numbers(TON)value of 349,and a good stability demonstrated in six cycle tests(equivalent to 216 h of testing).Through comprehensive studies,it was shown that CeNCl/C contains Lewis acid-base centers as active centers,which can effectively reduce the energy barrier required for ring opening of the reaction substrate,enhance the adsorption and activation of CO_(2),and promote the formation of intermediates,which led to the acquisition of excellent catalytic activity.

关键词： CO_(2)cycloaddition heterogeneous catalysis CeNCl Lewis acid/base

Highly conductive and stable iodine doped argyrodite electrolyte for all-solid-state lithium batteries

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Journal of Energy Chemistry 2025年第1期100卷 50-58页

作者： Gaozhan liu Jing Zhang Jing Yang Jinghui Chen Xingyue xiao Xiayin Yao Ningbo Institute of Materials Technology and Engineering Chinese Academy of Sciences Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of Sciences

Lithium argyrodites with high ionic conductivity and low cost are considered as one of the most prospective solid electrolytes for all-solid-state lithium ***,the poor chemical stability and compatibility with lithium metal limit their ***,Li5.4PS4.4Cl1.4I0.2solid electrolyte with high ionic conductivity of 11.49 m S cm-1and improved chemical stability is synthesized by iodine *** ultra-thin Li5.4PS4.4Cl1.4I0.2membrane with thickness of 10μm can be obtained by wet coating process,exhibiting a high ionic conductivity of 2.09 mS cm-1and low areal resistance of 1.17Ω***,iodine doping could in-situ form LiI at the lithium/electrolyte interface and improve the critical current density of Li5.4PS4.4Cl1.6from 0.8 to 1.35 mA *** resultant LiCoO2/Li5.4PS4.4Cl1.4I0.2/Li battery shows excellent cycling stability at 1 C,with a reversible specific capacity of 110.1 mA h g-1and a retention of 80.5% after 1000 *** addition,the assembled LiCoO2/Li5.4PS4.4Cl1.4I0.2membrane/Li pouch cell delivers an initial discharge capacity of 110.4 mA h g-1and 80.5% capacity retention after 100 cycles.

关键词： Argyrodite electrolytes Iodine doping Ionic conductivity Stability All-solid-state lithium battery

Enhanced post-combustion CO2 capture and direct air capture by plasma surface functionalization of graphene adsorbent

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Journal of Energy Chemistry 2025年第1期100卷 653-664页

作者： Rahul Navik Eryu Wang xiao Ding Huang Yunyi Yiyu liu Jia Li Guangdong-Hong Kong Joint Laboratory for Carbon Neutrality Jiangmen Laboratory of Carbon and Science and Technology Guangzhou HKUST Fok Ying Tung Research Institute The Hong Kong University of Science and Technology (Guangzhou) Carbon Neutrality and Climate Change Thrust Society Hub The Hong Kong University of Science and Technology (Guangzhou) Stoddart Institute of Molecular Science Department of Chemistry Zhejiang University

Graphene has enormous potential to capture CO2due to its unique properties and ***,graphene-based adsorbents have drawbacks of lower CO2adsorption capacity and poor *** work demonstrates a one-step rapid and sustainable N2/H2plasma treatment process to prepare graphene-based sorbent material with enhanced CO2adsorption *** treatment directly enriches amine species,increases surface area,and improves textural *** CO2adsorption capacity increases from 1.6 to 3.3 mmol/g for capturing flue gas,and from 0.14 to 1.3 mmol/g for direct air capture （DAC）.Importantly,the electrothermal property of the plasma-modified aerogels has been significantly improved,resulting in faster heating rates and significantly reducing energy consumption compared to conventional external heating for regeneration of *** aerogels display improved selectivity of 42 and 87 after plasma modification for 5 and 10 min,*** plasma-treated aerogels display minimal loss between 17%and 19% in capacity after 40 adsorption/desorption cycles,rendering excellent *** N2/H2plasma treatment of adsorbent materials would lower energy expenses and prevent negative effects on the global economy caused by climate change.

关键词： Carbon neutrality CO 2 capture Climate change Plasma treatment Graphene aerogel

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基于相关主题模型的程序网络自动构建与分析

电子学报 2017年第5期45卷 1052-1056页

作者：孙小兵刘湘月李斌张伟佳扬州大学信息工程学院江苏扬州225127 南京大学计算机软件新技术国家重点实验室江苏南京210023

程序理解的目的在于获得足够的软件系统信息,以适用于人理解的形式展现出来,辅助开发人员对软件的理解.本文通过使用相关主题模型,为软件系统类层次的代码文件建立程序网络,并可视化展示整个软件系统的相关结构和功能,辅助开发者理解整... 详细信息

程序理解的目的在于获得足够的软件系统信息,以适用于人理解的形式展现出来,辅助开发人员对软件的理解.本文通过使用相关主题模型,为软件系统类层次的代码文件建立程序网络,并可视化展示整个软件系统的相关结构和功能,辅助开发者理解整个程序代码.该技术综合考虑了软件代码中的结构性信息和内容性信息,所建立的程序网络可帮助开发者更好的理解程序的语法依赖关系和语义功能相关关系.实验验证了建立的程序网络具有较好的准确性以及可以为指定的类推荐相关类.

关键词：程序理解相关主题模型程序网络

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Analysis for the relevance of asthma susceptibility with the alteration and expression defect in integrin β4

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Analysis for the relevance of asthma susceptibility with the...

The on-line direct fitting of low signal-noise ratio single ion channel recordings based on hidden Markov models

中南地区第八届生理学学术大会

作者： Qin xiao-qun , xiang Yang, liu Chi, Zhou xiao-yan, Tan Yu-rong, liu Hui-jun, liu xiao-ai, Zhu xiao-lin (Department of Physiology, xiangya School of Medicine, Central South University, Changsha, Hunan 410078, People’s Republic of China)

＜正＞Adhesion molecules expressed on bronchial epithelial cells （BECs） play a vital role in airway hyperresponsiveness or airway inflammation. In order to probe the relationship between imbalance of expressions of ...

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Chinese Journal of Biomedical Engineering(English Edition) 2002年第2期11卷 51-60页

作者： HAN xiao dong,liu xiang ming,PAN Hua,TAO min,LIN Jia rui Institute of Biomedical Engineering, Huazhong University of Science and Technology, Wuhan 430074,China

Many kinds of channel currents are especially weak and the background noise dominates in the patch clamp recordings. This makes the threshold detection fail during estimating of the transition probabilities. So direct fitting of the patch clamp recording, not of the histogram coming from the recordings, is a desirable way to estimate the transition probabilities. Iterative batch EM algorithm based on hidden markov model has been used in this field but which has the "curse of dimensionality" and besides cant keep tracking the varying of the parameters. A new on line sequential iterative one is proposed here, which needs fewer computational efforts and can adaptively keep tracking the varying of parameters. Simulations suggest its robust, effective and convenient.

关键词： single ion channel recording hidden Markov model (HMM) on line algorithm Kullback Leibler (KL) information measure

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