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Critical respiratory failure due to pregnancy complicated by COVID-19 and bacterial coinfection:A case report

World Journal of Clinical Cases 2023年第23期11卷 5559-5566页

作者： Shuang Zhou Mei-Hong Liu xiao-peng deng Department of Pulmonary and Critical Care Medicine First Affiliated Hospital of Dalian Medical UniversityDalian 116011Liaoning ProvinceChina Department of Gynaecology and Obstetrics Dalian Women and Children’s Medical GroupDalian 116011Liaoning ProvinceChina

BACKGROUND In the past 3 years,the global pandemic of coronavirus disease 2019(COVID-19)has posed a great threat to human life and *** the causes of death in COVID-19 patients,combined or secondary bacterial infection is an important *** a special group,pregnant women experience varying degrees of change in their immune status,cardiopulmonary function,and anatomical structure during pregnancy,which puts them at higher risk of contracting ***-19 infection during pregnancy is associated with increased adverse events such as hospitalisation,admission to the intensive care unit,and mechanical ***,pregnancy combined with coinfection of COVID-19 and bacteria often leads to critical respiratory failure,posing severe challenges in the diagnosis and treatment *** SUMMARY We report a case of COVID-19 complicated with Staphylococcus aureus(***)coinfection in a pre-gnant woman at 34 wk of *** rapid progression of pulmonary lesions caused severe respiratory failure,and she received noninvasive ventilator-assisted respiratory ***,we delivered a foetus via emergency caesarean section after accelerating the maturity of the foetal pulmonary system,and the respiratory condition of the puerperant woman significantly improved after the delivery of the *** fluid was taken under tracheoscopy to quickly search for pathogens by the metagenomic nextgeneration sequencing(mNGS),and both COVID-19 and *** were *** targeted anti-infective treatment,the maternal condition gradually improved,and the patient was discharged from the *** The coinfection of pregnancy with COVID-19 and bacteria often leads to critical respiratory failure,which is a great challenge in the process of diagnosis and *** is crucial to choose the right time to deliver the foetus and to quickly find pathogens by mNGS.

关键词： Pregnancy Coronavirus disease 2019 Combined with staphylococcus aureus Metagenomic next-generation sequencing Critical respiratory failure Case report

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Electrochemical conversion of methane to bridge the gap in the artificial carbon cycle

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Journal of Energy Chemistry 2025年第1期100卷 286-308页

作者： Yuhao peng Yuefeng Song Ihar Razanau Juanxiu xiao Wei xiao Di Hu Guoxiong Wang College of Chemistry and Molecular Sciences Hubei Key Laboratory of Electrochemical Power Sources Wuhan University State Key Laboratory of Catalysis Dalian National Laboratory for Clean Energy iChEM (Collaborative Innovation Center of Chemistry for Energy Materials) Dalian Institute of Chemical Physics Chinese Academy of Sciences Laboratory of Physical-Chemical Technologies SSPA Scientific and Practical Materials Research Centre of NAS of Belarus State Key Laboratory of Marine Resources Utilization in South China Sea Collaborative Innovation Center of Marine Science and Technology School of Marine Science and Engineering Hainan University Department of Chemical and Environmental Engineering University of Nottingham Ningbo China

Methane, an abundant one-carbon（C1） resource, is extensively used in the industrial production of vital fuels and value-added chemicals. However, current industrial methane conversion technologies are energy-and carbon-intensive, mainly due to the high activation energy required to break the inert C–H bond, low selectivity, and problematic side reactions, including CO2emissions and coke deposition. Electrochemical conversion of methane（ECM） using intermittent renewable energy offers an attractive solution, due to its modular reactor design and operational flexibility across a broad spectrum of temperatures and pressures. This review emphasizes conversion pathways of methane in various reaction systems, highlighting the significance and advantages of ECM in facilitating a sustainable artificial carbon cycle. This work provides a comprehensive overview of conventional methane activation mechanisms and delineates the complete pathways of methane conversion in electrolysis contexts. Based on surface/interface chemistry, this work systematically analyzes proposed reaction pathways and corresponding strategies to enhance ECM efficiency towards various target products, including syngas, hydrocarbons, oxygenates, and advanced carbon materials. The discussion also encompasses opportunities and challenges for the ECM process, including insights into ECM pathways, rational electrocatalyst design, establishment of benchmarking protocols, electrolyte engineering, enhancement of CH4conversion rates, and minimization of CO2emission.

关键词： Activation energy

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Observation of acoustic hybrid topological phases induced by the p-d orbital interactions

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 132-139页

作者： xiao Xiang Feng Gao Yu-Gui peng peng Wu Zong-Lin Li Xue-Feng Zhu School of Physics and Innovation Institute Huazhong University of Science and Technology

In spinless systems,growing attention has recently been attracted to synthetic gauge fields,which redefine the fundamental crystal symmetries by utilizing the projective algebraic ***,synthetic gauge fields have been commonly investigated in single orbital systems,and explorations on hybrid orbitals remain elusive in ***,we report the experimental observation of hybrid topological phases induced by hybrid synthetic gauge flux,which is formed by the interaction between p and d orbitals embedded in acoustic *** breaking the translation symmetries of Lxand/or Ly,we unambiguously demonstrate the first-order M?bius edge states and higher-order corner *** work establishes a platform for seeking exotic topological phases induced by hybrid-orbitals interactions and initializing the framework of hybrid-orbitalsrelated topological *** applications can be anticipated in scenarios such as high-quality sensing and robust wave trapping due to the stepwise energy distribution of the hybrid topological phase.

关键词： topological insulator synthetic gauge field projective symmetry corner states

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多时段露天矿生产计划整体优化模型

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东北大学学报（自然科学版） 2016年第10期37卷 1460-1464页

作者：孙效玉邓鹏宏赵明东北大学资源与土木工程学院辽宁沈阳110819 鞍钢矿业公司决策支持部辽宁鞍山114004 中煤科工集团沈阳设计研究院有限公司露天工程事业部辽宁沈阳110015

针对数学优化方法在露天矿进度计划应用中存在的只对单一时段计划进行优化,或是对多时段计划进行分段优化,没有实现全时段整体优化的问题,在前后时段0-1整数规划和大小时段0-1整数规划两种模型分段优化的前期工作基础上,提出了露天矿整... 详细信息

针对数学优化方法在露天矿进度计划应用中存在的只对单一时段计划进行优化,或是对多时段计划进行分段优化,没有实现全时段整体优化的问题,在前后时段0-1整数规划和大小时段0-1整数规划两种模型分段优化的前期工作基础上,提出了露天矿整体优化的0-1整数规划模型,并针对计算速度慢的问题,提出了相应的改进措施.该模型既实现了多时段生产计划的整体优化,又解决了分段优化无解的隐患,还保证了速度和精度,不仅可实现用下层计划验证上层计划,而且可用于由下层计划导出上层计划,其实用性和通用性更好.

关键词：露天矿生产进度计划 0-1整数规划线性规划整体优化多时段

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Sulfolane‑Based Flame‑Retardant Electrolyte for High‑Voltage Sodium‑Ion Batteries

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Nano-Micro Letters 2025年第2期17卷 498-516页

作者： Xuanlong He Jie peng Qingyun Lin Meng Li Weibin Chen Pei Liu Tao Huang Zhencheng Huang Yuying Liu Jiaojiao deng Shenghua Ye Xuming Yang Xiangzhong Ren xiaoping Ouyang Jianhong Liu Biwei xiao Jiangtao Hu Qianling Zhang Graphene Composite Research Center College of Chemistry and Environmental EngineeringShenzhen UniversityShenzhen 518060People’s Republic of China Center of Electron Microscopy State Key Laboratory of Silicon and Advanced Semiconductor MaterialsSchool of Materials Science and EngineeringZhejiang UniversityHangzhou 310027People’s Republic of China GRINM(Guangdong)Research Institute for Advanced Materials and Technology FoshanGuangdong 528051People’s Republic of China College of Energy Engineering Zhejiang UniversityHangzhouZhejiang 310027People’s Republic of China School of Materials Science and Engineering Xiangtan UniversityXiangtan 411105People’s Republic of China Shenzhen Eigen-Equation Graphene Technology Co.Ltd Shenzhen 518000People’s Republic of China

Sodium-ion batteries hold great promise as next-generation energy storage ***,the high instability of the electrode/electrolyte interphase during cycling has seriously hindered the development of *** particular,an unstable cathode–electrolyte interphase(CEI)leads to successive electrolyte side reactions,transition metal leaching and rapid capacity decay,which tends to be exacerbated under high-voltage ***,constructing dense and stable CEIs are crucial for high-performance *** work reports localized high-concentration electrolyte by incorporating a highly oxidation-resistant sulfolane solvent with non-solvent diluent 1H,1H,5H-octafluoropentyl-1,1,2,2-tetrafluoroethyl ether,which exhibited excellent oxidative stability and was able to form thin,dense and homogeneous *** excellent CEI enabled the O3-type layered oxide cathode NaNi_(1/3)Mn_(1/3)Fe_(1/3)O_(2)(NaNMF)to achieve stable cycling,with a capacity retention of 79.48%after 300 cycles at 1 C and 81.15%after 400 cycles at 2 C with a high charging voltage of 4.2 *** addition,its nonflammable nature enhances the safety of *** work provides a viable pathway for the application of sulfolane-based electrolytes on SIBs and the design of next-generation high-voltage electrolytes.

关键词： Sodium-ion batteries Sulfolane-based electrolyte High voltage Layered oxide cathode Flame retardant

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形变热处理对Cu-11Zn-0.5Cr合金时效组织和性能的影响

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中国有色金属学报 2017年第3期27卷 496-503页

作者：王霖倩王日初王小锋彭建邓敏中南大学材料科学与工程学院长沙410083

采用光学显微镜(OM)和透射电镜(TEM)观察和分析形变热处理对Cu-11Zn-0.5Cr合金显微组织的影响,并测定不同时效工艺合金的力学性能和电学性能。结果表明:合金最佳形变热处理工艺为热挤压-在线水淬-18%冷拉-(450℃,4 h)时效,经此最佳形变... 详细信息

采用光学显微镜(OM)和透射电镜(TEM)观察和分析形变热处理对Cu-11Zn-0.5Cr合金显微组织的影响,并测定不同时效工艺合金的力学性能和电学性能。结果表明:合金最佳形变热处理工艺为热挤压-在线水淬-18%冷拉-(450℃,4 h)时效,经此最佳形变热处理工艺处理后其硬度、拉伸强度和相对电导率可分别达到128HB、385MPa和41.72%IACS。合金性能主要受时效过程中的时效析出过程和回复-再结晶过程控制。在时效过程中,基体内溶质原子析出形成细小弥散第二相造成析出强化,且第二相对电子的散射作用较溶质原子的弱,使得合金强度和电导率均增大。回复与再结晶使结构中的变形畸变及缺陷消除,使得合金强度减小而电导率增大。

关键词： Cu-Zn-Cr合金形变热处理组织力学性能导电性能

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Reduced mesencephalic astrocyte-derived neurotrophic factor expression by mutant androgen receptor contributes to neurodegeneration in a model of spinal and bulbar muscular atrophy pathology

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Neural Regeneration Research 2025年第9期20卷 2655-2666页

作者： Yiyang Qin Wenzhen Zhu Tingting Guo Yiran Zhang Tingting Xing peng Yin Shihua Li xiao-Jiang Li Su Yang Guangdong Key Laboratory of Non-human Primate Research Key Laboratory of CNS Regeneration(Ministry of Education)Guangdong–HongKong–Macao Institute of CNS RegenerationJinan UniversityGuangzhouGuangdong ProvinceChina

Spinal and bulbar muscular atrophy is a neurodegenerative disease caused by extended CAG trinucleotide repeats in the androgen receptor gene,which encodes a ligand-dependent transcription facto *** mutant androgen receptor protein,characterized by polyglutamine expansion,is prone to misfolding and forms aggregates in both the nucleus and cytoplasm in the brain in spinal and bulbar muscular atrophy *** aggregates alter protein-protein interactions and compromise transcriptional *** this study,we reported that in both cultured N2a cells and mouse brain,mutant androgen receptor with polyglutamine expansion causes reduced expression of mesencephalic astrocyte-de rived neurotrophic *** n of mesencephalic astrocyte-derived neurotrophic factor amelio rated the neurotoxicity of mutant androgen receptor through the inhibition of mutant androgen receptor *** down endogenous mesencephalic astrocyte-derived neurotrophic factor in the mouse brain exacerbated neuronal damage and mutant androgen receptor *** findings suggest that inhibition of mesencephalic astrocyte-derived neurotrophic factor expression by mutant androgen receptor is a potential mechanism underlying neurodegeneration in spinal and bulbar muscular atrophy.

关键词： androgen receptor mesencephalic astrocyte-derived neurotrophic factor mouse model neurodegeneration neuronal loss neurotrophic factor polyglutamine disease protein misfolding spinal and bulbar muscular atrophy transcription factor

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U6和H1双启动子载体用于RNAi的实验研究

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中国生物工程杂志 2004年第11期24卷 26-29,31页

作者：蹇锐程小星彭涛邓少丽蒋静重庆市第三军医大学微生物学教研室重庆400038

为建立一条简便、有效的构建哺乳动物细胞随机RNAi文库技术路线 ,首先通过PCR将 1 9～ 2 1ntsiRNA编码序列及终止信号等元件引入U6启动子下游 ,再将该扩增产物定向克隆至H1启动子的下游。构建的双启动子载体中 ,U6和H1相对排列 ,均以其... 详细信息

为建立一条简便、有效的构建哺乳动物细胞随机RNAi文库技术路线 ,首先通过PCR将 1 9～ 2 1ntsiRNA编码序列及终止信号等元件引入U6启动子下游 ,再将该扩增产物定向克隆至H1启动子的下游。构建的双启动子载体中 ,U6和H1相对排列 ,均以其间插入的靶序列为模板 ,分别转录出其正义和反义链 ,形成功能性siRNA。以EGFP和bcl 2为靶基因的实验表明 ,该方法构建的载体可有效地干扰相应基因的表达。

关键词： RNA 载体反义启动子实验研究 bcl-2 靶基因哺乳动物细胞定向克隆转录

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内冲击激发式安全雷管的研制与适配性测试

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火工品 2025年第1期 1-6页

作者：邓小娟代鹏举董金龙刘晓娟王爱上海鲲程电子科技有限公司上海201100 广东宏大民爆集团有限公司广东广州510000 湖南湘科控股集团有限公司湖南长沙410000 江西新余国泰特种化工有限责任公司江西新余338000 湖南神斧集团湘南爆破器材有限责任公司湖南永州425000

针对工业雷管在使用过程中因起爆药感度高而引发的安全事故和环境污染问题,研制了一种新型内冲击激发式安全雷管(简称“IID雷管”),并开展其与不同点火药的适配性测试。通过采用猛炸药作为主要装药,以及设计激发组件,实现了高效有序的... 详细信息

针对工业雷管在使用过程中因起爆药感度高而引发的安全事故和环境污染问题,研制了一种新型内冲击激发式安全雷管(简称“IID雷管”),并开展其与不同点火药的适配性测试。通过采用猛炸药作为主要装药,以及设计激发组件,实现了高效有序的起爆和传爆过程;通过与不同点火药的适配测试,以及对起爆能力、延期精度等关键功能的全面评估,验证了IID雷管在与LTNR和K-K等药剂适配时,各项性能均满足行业标准。此外,IID雷管结构工艺简单、安全环保,具有广泛的应用前景。

关键词：安全雷管数码电子雷管内冲击激发无起爆药雷管激发组件

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五指毛桃抗衰老作用研究

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内蒙古中医药 2016年第12期35卷 112-113页

作者：叶碧颜彭小敏邓广海广州市天河区中医医院广州市510000 广东省中医院 510000

目的:探讨五指毛桃水提物的抗衰老活性,为日后的合理用药提供科学依据。方法:采用D-半乳糖皮下注射法制备小鼠亚急性衰老模型,以不同浓度的五指毛桃水煎灌胃观察20d,并与空白对照组及衰老模型组比较,测定五指毛桃对血清自由基代谢指标... 详细信息

目的:探讨五指毛桃水提物的抗衰老活性,为日后的合理用药提供科学依据。方法:采用D-半乳糖皮下注射法制备小鼠亚急性衰老模型,以不同浓度的五指毛桃水煎灌胃观察20d,并与空白对照组及衰老模型组比较,测定五指毛桃对血清自由基代谢指标超氧化物歧化酶(T-SOD)和活性丙二醛(MDA)含量的影响,初步分析其抗衰老作用。结果:五指毛桃水提液具有提升亚急性衰老小鼠T-SOD活性,降低亚急性衰老小鼠MDA含量的作用,给药各组与衰老模型组均有显著性差异(P<0.05)。结论:五指毛桃具有一定的抗衰老作用。

关键词：五指毛桃抗衰老超氧化物歧化酶丙二醛

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