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Critical respiratory failure due to pregnancy complicated by COVID-19 and bacterial coinfection:A case report

作     者:Shuang Zhou Mei-Hong Liu Xiao-Peng Deng 

作者机构:Department of Pulmonary and Critical Care MedicineFirst Affiliated Hospital of Dalian Medical UniversityDalian 116011Liaoning ProvinceChina Department of Gynaecology and ObstetricsDalian Women and Children’s Medical GroupDalian 116011Liaoning ProvinceChina 

出 版 物:《World Journal of Clinical Cases》 (世界临床病例杂志)

年 卷 期:2023年第11卷第23期

页      面:5559-5566页

核心收录:

学科分类:1002[医学-临床医学] 100201[医学-内科学(含:心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主  题:Pregnancy Coronavirus disease 2019 Combined with staphylococcus aureus Metagenomic next-generation sequencing Critical respiratory failure Case report 

摘      要:BACKGROUND In the past 3 years,the global pandemic of coronavirus disease 2019(COVID-19)has posed a great threat to human life and *** the causes of death in COVID-19 patients,combined or secondary bacterial infection is an important *** a special group,pregnant women experience varying degrees of change in their immune status,cardiopulmonary function,and anatomical structure during pregnancy,which puts them at higher risk of contracting ***-19 infection during pregnancy is associated with increased adverse events such as hospitalisation,admission to the intensive care unit,and mechanical ***,pregnancy combined with coinfection of COVID-19 and bacteria often leads to critical respiratory failure,posing severe challenges in the diagnosis and treatment *** SUMMARY We report a case of COVID-19 complicated with Staphylococcus aureus(***)coinfection in a pre-gnant woman at 34 wk of *** rapid progression of pulmonary lesions caused severe respiratory failure,and she received noninvasive ventilator-assisted respiratory ***,we delivered a foetus via emergency caesarean section after accelerating the maturity of the foetal pulmonary system,and the respiratory condition of the puerperant woman significantly improved after the delivery of the *** fluid was taken under tracheoscopy to quickly search for pathogens by the metagenomic nextgeneration sequencing(mNGS),and both COVID-19 and *** were *** targeted anti-infective treatment,the maternal condition gradually improved,and the patient was discharged from the *** The coinfection of pregnancy with COVID-19 and bacteria often leads to critical respiratory failure,which is a great challenge in the process of diagnosis and *** is crucial to choose the right time to deliver the foetus and to quickly find pathogens by mNGS.

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