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Single-incision laparoscopic transabdominal preperitoneal repair in the treatment of adult female patients with inguinal hernia

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World Journal of Gastrointestinal Surgery 2024年第1期16卷 49-58页

作者： xiao-jun zhu Jing-Yi Jiao Hui-Min Xue Peng Chen Chang-Fu Qin Peng Wang Department of General Surgery The Affiliated Hospital of Nantong UniversityNantong 226001Jiangsu ProvinceChina Medical School Nantong UniversityNantong 226001Jiangsu ProvinceChina Department of Hernia and Abdominal Wall Surgery Peking University People's HospitalBeijing 100044China

BACKGROUND Women have a 3%lifetime chance of developing an inguinal hernia,which is not as common in *** to its cosmetic benefits,single-incision laparoscopic transabdominal preperitoneal(SIL-TAPP)inguinal hernia repair is becoming in-creasingly popular in the management of inguinal hernia in ***,there are no studies comparing the safety and applicability of SIL-TAPP repair with conventional laparoscopic transabdominal preperitoneal(CL-TAPP)inguinal hernia repair for the treatment of inguinal hernia in *** To compare the outcomes of SIL-TAPP and CL-TAPP repair in adult female patients with inguinal hernia and to estimate the safety and applicability of SIL-TAPP repair in adult female inguinal hernia *** We retrospectively compared the clinical information and follow-up data of fe-male inguinal hernia patients who underwent SIL-TAPP inguinal hernia repair and those who underwent CL-TAPP inguinal hernia repair at the Affiliated Hos-pital of Nantong University from February 2018 to December 2020 and assessed the long-term and short-term outcomes of both *** This study included 123 patients,with 71 undergoing SIL-TAPP repair and 52 un-dergoing CL-TAPP *** two cohorts of patients and inguinal hernia charac-teristics were similar,with no statistically meaningful *** rate of intraoperative inferior epigastric vessel injury was lower in patients in the SIL-TAPP cohort(0,0%)than in patients in the CL-TAPP cohort(4,7.7%)and was significantly different(P<0.05).In addition,the median[interquartile range(IQR)]total hospitalization costs were significantly lower in patients in the SIL-TAPP cohort[$3287(3218-3325)]than in patients in the CL-TAPP cohort[$3511(3491-3599)].Postoperatively,the occurrence rate of trocar site hernia was lower in the SIL-TAPP cohort(0,0%)than in the CL-TAPP cohort(4,7.7%),and the median(IQR)cosmetic score was significantly higher in the SIL-TAPP cohort[10(10-10)]than in the CL-TAPP cohort[9(9

关键词： Single-incision Groin hernia Female Inguinal hernia Laparoscopic transabdominal preperitoneal inguinal hernia repair

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Robot-assisted partial splenectomy for benign splenic tumors:Four case reports

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World Journal of Clinical Oncology 2024年第10期15卷 1366-1375页

作者： Hui-Min Xue Peng Chen xiao-jun zhu Jing-Yi Jiao Peng Wang Department of General Surgery The Affiliated Hospital of Nantong UniversityNantong 226001Jiangsu ProvinceChina Medical School Nantong UniversityNantong 226001Jiangsu ProvinceChina

BACKGROUND Robotic-assisted partial splenectomy(RAPS)is a superior approach for treating splenic cysts and splenic hemangiomas,as it preserves the immune function of the spleen and reduces the risk of overwhelming post splenectomy ***-tly,there are no standardized guidelines for performing a partial *** SUMMARY Four patients with splenic cysts or splenic hemangiomas were treated by *** aspects with RAPS include carefully dissecting the splenic pedicle,accurately identifying and ligating the supplying vessels of the targeted segment,and ensuring precise hemostasis during splenic parenchymal *** successful RAPS cases are presented,where the tumors were removed by pret-reating the splenic artery,dissecting and ligating the corresponding segmental vessels of the splenic pedicle,transecting the ischemic segment of the spleen,and using electrocautery for optimal *** patients underwent successful surgeries with minimal bleeding during the procedure,and there were no signs of bleeding or recurrence *** Four cases confirm the feasibility and superiority of RAPS for the treatment of benign splenic tumors.

关键词： Partial splenectomy Robotic-assisted partial splenectomy Splenic cyst Splenic hemangiomas Case report

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Influence of baryons on the spatial distribution of matter:higher order correlation functions

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Research in Astronomy and Astrophysics 2012年第12期12卷 1603-1612页

作者： xiao-jun zhu jun Pan Purple Mountain Observatory Chinese Academy of Sciences Nanjing 210008 China National Astronomical Observatories Chinese Academy of Sciences B eijing 100012 China

Physical processes involving baryons could leave a non-negligible imprint on the distribution of cosmic matter.A series of simulated data sets at high resolution with identical initial conditions are employed for count-in-cell analysis,including one N-body pure dark matter run,one with only adiabatic gas and one with dissipative *** and higher order cumulants Sn of dark matter and gas are *** is found that physical processes with baryons mainly affect distributions of dark matter at scales less than 1 h-1 *** comparison with the pure dark matter run,adiabatic processes alone strengthen the variance of dark matter by～10%at a scale of 0.1 h-1 Mpc,while the Sn parameters of dark matter only mildly deviate by a few *** dissipative gas run does not differ much from the adiabatic run in terms of variance for dark matter,but renders significantly different Sn parameters describing the dark matter,bringing about a more than 10%enhancement to S3 at 0.1 h-1 Mpc and z=0 and being even larger at a higher *** patterns of gas in two hydrodynamical simulations are quite *** of gas at z=0 decreases by～30%in the adiabatic simulation but by～60%in the nonadiabatic simulation at 0.1 h-1 *** attenuation is weaker at larger scales but is still obvious at～10 h-1 *** parameters of gas are biased upward at scales 〈～4 h-1 Mpc,and dissipative processes show an～84%promotion at z=0 to S3 at 0.1 h-1 Mpc in contrast with the～7%change in the adiabatic *** segregation in clustering between gas and dark matter could have dramatic implications on modeling distributions of galaxies and relevant cosmological applications demanding fine details of matter distribution in a strongly nonlinear regime.

关键词： cosmology:dark matter-large-scale structure of universe-methods: statistical

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Minimum Time Extrema Estimation for Large-Scale Radio-Frequency Identification Systems

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Journal of Computer Science & Technology 2020年第5期35卷 1099-1114页

作者： xiao-jun zhu Li-Jie Xu xiao-Bing Wu Bing Chen College of Computer Science and Technology Nanjing University of Aeronautics and AstronauticsNanjing 211106China Jiangsu Key Laboratory of Dig Data Security and Intelligent Processing Nanjing University of Posts and TelecommunicationsNanjing 210049China Wireless Research Centre University of CanterburyChristchurch 8041New Zealand

We consider the extrema estimation problem in large-scale radio-frequency identification(RFID)systems,where there are thousands of tags and each tag contains a finite *** objective is to design an extrema estimation protocol with the minimum execution *** the standard binary search protocol wastes much time due to inter-frame overhead,we propose a parameterized protocol and treat the number of slots in a frame as an unknown *** formulate the problem and show how to find the best parameter to minimize the worst-case execution ***,we propose two rules to further reduce the execution *** first is to find and remove redundant *** second is to concatenate a frame from minimum value estimation with a frame from maximum value estimation to reduce the total number of *** show that,in a typical scenario,the proposed protocol reduces execution time by 79%compared with the standard binary search protocol.

关键词： radio-frequency identification(RFID)system maximum value estimation minimum value estimation time efficient protocol

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Systematic study of the synthesis of heavy and superheavy nuclei in 48Ca-induced fusion-evaporation reactions

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Nuclear Science and Techniques 2024年第7期35卷 157-172页

作者： Shi-Hao zhu Tian-Liang Zhao xiao-jun Bao Department of Physics Collaborative Innovation Center for Quantum EffectsKey Laboratory of Low Dimensional Quantum Structures and Quantum Control of Ministry of EducationHunan Normal UniversityChangsha410081China School of Nuclear Science and Technology Lanzhou UniversityLanzhou730000China School of Physics Xi’an Jiaotong UniversityXi’an710049China

We systematically studied the evaporation residue cross sections of ^(48)Ca-induced reactions on lanthanide and actinide target nuclei under the Dinuclear System(DNS)model framework to check the reliability and applicability of the *** produce new proton-rich Fl and Lv isotopes through hot fusion reactions in the superheavy element region with Z≥104,we utilized the reactions ^(48)Ca+^(236,238,239) Pu and ^(48)Ca+^(242,243,244,250) ***,owing to the detection limit of available equipment(0.1 pb),only 283Fl and 287−289Lv,which have the maximum evaporation residue cross section values of 0.149,0.130,9.522,and 0.309 pb,respectively,can be ***,to produce neutron-deficient isotopes of actinides near the proton drip line with Z=93−100,we attempted to generate the new isotopes(224−227Pu,228−232,237Cm)using the reactions ^(48)Ca+180,182,183 W and ^(48)Ca+^(184,186,187,192) *** maximum evaporation residue cross section values are 0.07,0.06,0.26,and 0.30 nb for the former set of reactions,and 1.96 pb,5.73 pb,12.16 pb,19.39 pb,54.79 pb,and 6.45 nb for the latter,*** results are expected to provide new information for the future synthesis of unknown neutron-deficient isotopes.

关键词： Dinuclear system(DNS)model Evaporation residue cross section Neutron-deficient isotopes

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Research progress on the immune microenvironment of the gallbladder in patients with cholesterol gallstones

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World Journal of Gastrointestinal Surgery 2022年第9期14卷 887-895页

作者： Jing-Yi Jiao xiao-jun zhu Chun Zhou Peng Wang Department of Hepatobiliary and Pancreatic Surgery Affiliated Hospital of Nantong UniversityNantong 226001Jiangsu ProvinceChina Medical School Nantong UniversityNantong 226001Jiangsu ProvinceChina Department of Hepatobiliary Surgery Nantong First People's HospitalNantong 226001Jiangsu ProvinceChina Department of General Practitioner Affiliated Hospital of Nantong UniversityNantong 226001Jiangsu ProvinceChina

Cholesterol gallstones are very common in hepatobiliary surgery and have been studied to a certain extent by doctors worldwide for ***,the mechanism of cholesterol gallstone formation is not fully understood,so there is currently no completely effective drug for the treatment and prevention of cholesterol *** formation and development of cholesterol gallstones are caused by a variety of genetic and environmental factors,among which genetic susceptibility,intestinal microflora disorders,impaired gallbladder motility,and immune disorders are important in the pathogenesis of cholesterol *** review focuses on recent advances in these *** also discuss some new targets that may be effective in the treatment and prevention of cholesterol gallstones,which may be hot areas in the future.

关键词： Microflora Cholesterol gallstones Gallbladder Pathogenesis Immune disorders

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Asymptotic Inference in the Random Coefficient Autoregressive Model with Time-functional Variance Noises

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Acta Mathematicae Applicatae Sinica 2024年第2期40卷 320-346页

作者： En-wen zhu Zi-wei DENG Han-jun ZHANG jun CAO xiao-hui LIU Department of Mathematics and Statistics Changsha University of Science and TechnologyChangsha 410114China School of Mathematics and Computational Science Xiangtan UniversityXiangtan 411105China School of Statistics and Data Science and Key Laboratory of Data Science in Finance and EconomicsJiangxi University of Finance and EconomicsNanchang 330013China

This paper considers the random coefficient autoregressive model with time-functional variance noises,hereafter the RCA-TFV *** first establish the consistency and asymptotic normality of the conditional least squares estimator for the constant *** semiparametric least squares estimator for the variance of the random coefficient and the nonparametric estimator for the variance function are constructed,and their asymptotic results are reported.A simulation study is presented along with an analysis of real data to assess the performance of our method in finite samples.

关键词： random coefficient autoregressive model time-functional variance conditional least squares semiparametric least squares

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Isocyanide-Based One-Pot Cascade Synthesis of 3-Acyl Isoindolinones

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Chinese Journal of Chemistry 2024年第3期42卷 259-263页

作者： Jia Liu Yi-Ming zhu xiao-Ping Xu Shun-jun Ji Key Laboratory of Organic Synthesis of Jiangsu Province College of ChemistryChemical Engineering and Materials Science & Collaborative Innovation Center of Suzhou Nano Science and TechnologySoochow UniversitySuzhouJiangsu215123 China Suzhou Baolidi Functional Materials Research Institute SuzhouJiangsu215144 China

A series of 3-acyl-substituted isoindolinone derivatives were synthesized in a one-pot manner via the reaction of o-bromobenzaldehydes,isocyanides,and carboxylic acids in the presence of palladium catalyst and base. The reaction employing easily available starting materials features simple operation and high efficiency. The mechanistic study showed that the reaction might undergo 1) Pd-catalyzed [3+2] cyclization of o-bromobenzaldehyde with isocyanide and the re-insertion of another molecule of isocyanide,2) addition of carboxylic acid to in situ formed ketenimine followed by a rearrangement relay to give 3,3-diacyl-substituted isoindolinone derivative. Further transformations of the obtained products through decarbonylation could also be realized.

关键词： One-pot reaction Isocyanide Pd catalysis Rearrangement reaction Isoindolinone

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On the Monge–Kantorovich Mass Transfer Problem in Higher Dimensions

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Acta Mathematica Sinica,English Series 2024年第8期40卷 1989-2004页

作者： xiao jun LU School of Mathematics Southeast UniversityNanjing 210096P.R.China

This paper mainly investigates the approximation of a global maximizer of the Monge–Kantorovich mass transfer problem in higher dimensions through the approach of nonlinear partial differential equations with Dirichlet *** an approximation mechanism,the primal maximization problem can be transformed into a sequence of minimization *** applying the systematic canonical duality theory,one is able to derive a sequence of analytic solutions for the minimization *** the final analysis,the convergence of the sequence to an analytical global maximizer of the primal Monge–Kantorovich problem will be demonstrated.

关键词： Monge-Kantorovich mass transfer singular variational problem canonical duality theory

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Elemene Antitumor Drugs Development Based on "Molecular Compatibility Theory" and Clinical Application: A Retrospective and Prospective Outlook

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Chinese Journal of Integrative Medicine 2024年第1期30卷 62-74页

作者： JIANG xiao-ying SHI Li-ping zhu jun-long BAI Ren-ren XIE Tian School of Pharmacy Hangzhou Normal UniversityHangzhou(311121)China Key Laboratory of Elemene Class Anti-cancer Chinese Medicines Engineering Laboratory of Development and Application of Traditional Chinese MedicinesCollaborative Innovation Center of Traditional Chinese Medicines of Zhejiang ProvinceHangzhou Normal UniversityHangzhou(311121)China Good Clinical Practice Center Affliliated Hospital of Nanjing University of Chinese MedicineNanjing(210000)China

Elemene, derived from Curcuma wenyujin, one of the "8 famous genuine medicinal materials of Zhejiang province," exhibits remarkable antitumor activity. It has gained wide recognition in clinical practice for effectiveness on tumors. Dr. XIE Tian introduced the innovative concept of "molecular compatibility theory" by combining Chinese medicine principles, specifically the "monarch, minister, assistant, and envoy" theory, with modern biomedical technology. This groundbreaking approach, along with a systematic analysis of Chinese medicine and modern biomedical knowledge, led to the development of elemene nanoliposome formulations. These novel formulations offer numerous advantages, including low toxicity, well-defined composition, synergistic effects on multiple targets, and excellent biocompatibility. Following the principles of the "molecular compatibility theory", further exploration of cancer treatment strategies and methods based on elemene was undertaken. This comprehensive review consolidates the current understanding of elemene's potential antitumor mechanisms, recent clinical investigations, advancements in drug delivery systems, and structural modifications. The ultimate goal of this review is to establish a solid theoretical foundation for researchers, empowering them to develop more effective antitumor drugs based on the principles of "molecular compatibility theory".

关键词： molecular compatibility theory Chinese integrative medicine elemene antitumor activity drug delivery structural modification

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