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Inflammatory airway features and hypothalamic-pituitary- adrenal axis function in asthmatic rats combined with chronic obstructive pulmonary disease

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Chinese Medical Journal 2010年第13期123卷 1720-1726页

作者： CAI Cui ZHANG hong-ying LE Jing-jing DONG Jing-cheng CUI Yan XU Chang-qing LIU Bao-jun WU Jin-feng DUAN xiao-hong cao Yu-xue Lab of Integrative Medicine for Lung Inflammation and Cancers Huashan Hospital Fudan University Shanghai 200040 China

Background Bronchial asthma （BA） and chronic obstructive pulmonary disease （COPD） are both inflammatory airway diseases with different characteristics. However, there are many patients who suffer from both BA and COPD. This study was to evaluate changes of inflammatory airway features and hypothalamic-pituitary-adrenal （HPA） axis function in asthmatic rats combined with COPD. Methods Brown Norway （BN） rats were used to model These three models were compared and evaluated with the inflammatory airway diseases of BA, COPD and COPD＋BA. respect to clinical symptoms, pulmonary histopathology, airway hyperresponsiveness （AHR）, inflammatory cytokines and HPA axis function. Results The inflammatory airway features and HPA axis function in rats in the COPD＋BA model group were greatly influenced. Rats in this model group showed features of the inflammatory diseases BA and COPD. The expression of inflammatory cytokines in this model group might be up or downregulated when both disease processes are present. The levels of corticotrophin releasing hormone mRNA and corticosterone in this model group were both significantly decreased than those in the control group （P 〈0.05）. Conclusions BN rat can be used as an animal model of COPD＋BA. By evaluating this animal model we found that the features of inflammation in rats in this model group seem to be exaggerated. The HPA axis functions in rats in this model group have been disturbed or impaired, which is prominent at the hypothalamic level.

关键词： chronic obstructive pulmonary disease bronchial asthma inflammatory airway disease hypothalamic-pituitary-adrenal axis

Ternary-phase layered cathodes toward ultra-stable and highrate sodium ion storage

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Rare Metals 2024年第4期43卷 1589-1598页

作者： Wen-Ji Yin Pei-Dan Su Qi Lu xiao-Qiong Li Ji-Ming Peng Teng-Fei Zhou Ge-Meng Liang Yu-Liang cao hong-Qiang Wang Qing-Yu Li Si-Jiang Hu Guangxi Key Laboratory of Low Carbon Energy Materials School of Chemistry and Pharmaceutical SciencesGuangxi Normal UniversityGuilin541004China Institutes of Physical Science and Information Technology Anhui UniversityHefei230601China Department of Chemistry and Pharmaceutical Sciences Guilin Normal CollegeGuilin541199China College of Chemistry and Chemical Engineering Huanggang Normal UniversityHuanggang438000China School of Chemical Engineering and Advanced Materials The University of AdelaideAdelaide5005Australia Engineering Research Center of Organosilicon Compounds and Materials of Ministry of Education College of Chemistry and Molecular SciencesWuhan UniversityWuhan430072China

With the shortage of lithium resources,sodiumion batteries(SIBs)are considered one of the most promising candidates for lithium-ion batteries.P2-type and O3-type layered oxides are one of the few cathodes that can access high energy ***,they usually exhibit structural change,capacity decay,and slow Na ion ***,we present layered ternary-phase cathodes with P2,P3 and O3 phases by a lattice doping strategy,which is demonstrated by X-ray diffraction(XRD)*** the characteristics of P2,P3 and O3 phases,the layered composites show performance improvement during long-term battery *** particular,Na_(0.7)Li_(0.1)Co_(0.3-)Fe_(0.3)Mn_(0.3)O_(2)(NLCFM)delivers a reversible capacity of120.1 mAh·g^(-1)at 0.1C(1.0C=175 mA·g^(-1))with a superior capacity retention of 72.5%after 1000 cycles *** work offers insights into the development of advanced cathode materials for SIBs.

关键词： Sodium-ion battery Cathode material Layered oxides Lattice doping Mixed phase

Event-triggered impulsive synchronization of heterogeneous neural networks

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Science China(Information Sciences) 2024年第2期67卷 331-332页

作者： Zhengxin WANG Chongfang JIN Wangli HE Min xiao Guo-Ping JIANG Jinde cao College of Science Nanjing University of Posts and Telecommunications Jiangsu Engineering Lab for IOT Intelligent Robots (IOTRobot) Nanjing University of Posts and Telecommunications Key Laboratory of Smart Manufacturing in Energy Chemical Process Ministry of EducationEast China University of Science and Technology School of Automation Nanjing University of Posts and Telecommunications School of Mathematics Southeast University Yonsei Frontier Lab Yonsei University

Synchronization is one of the most important dynamics in neural networks. Several scholars have studied the quasi-synchronization of heterogeneous neural networks [1],wherein external controllers play a significant role. Impulsive control, a kind of energy-saving control, is activated instantaneously only at specific discrete moments.

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Research on Quantitative Identification of Three-Dimensional Connectivity of Fractured-Vuggy Reservoirs

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Energy Engineering 2024年第5期121卷 1195-1207页

作者： Xingliang Deng Peng cao Yintao Zhang Yuhui Zhou xiao Luo Liang Wang Exploration and Development Research Institute PetroChina Tarim Oilfield CompanyKorla841000China PetroChina Hangzhou Research Institute of Geology Hangzhou310023China School of Petroleum Engineering Yangtze UniversityWuhan430100China

The fractured-vuggy carbonate oil resources in the western basin of China are extremely *** connectivity of carbonate reservoirs is complex,and there is still a lack of clear understanding of the development and topological structure of the pore space in fractured-vuggy ***,effective prediction of fractured-vuggy reservoirs is *** view of this,this work employs adaptive point cloud technology to reproduce the shape and capture the characteristics of a fractured-vuggy *** identify the complex connectivity among pores,fractures,and vugs,a simplified one-dimensional connectivity model is established by using the meshless connection element method(CEM).Considering that different types of connection units have different flow characteristics,a sequential coupling calculation method that can efficiently calculate reservoir pressure and saturation is *** automatic history matching,the dynamic production data is fitted in real-time,and the characteristic parameters of the connection unit are *** results show that the three-dimensional connectivity model of the fractured-vuggy reservoir built in this work is as close as 90%of the fine grid model,while the dynamic simulation efficiency is much higher with good accuracy.

关键词： Fractured-vuggy reservoir three-dimensional connectivity connection unit dynamic prediction automatic history matching

Reveal the pharmacodynamic substances and mechanism of an edible medicinal plant Rhodiola crenulate in DSS-induced colitis through plasma pharmacochemistry and metabolomics

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Food Science and Human Wellness 2024年第4期13卷 2116-2131页

作者： Yu Peng xiaoao xiao Tingting Ji Xinyuan Wang Yixuan Xu Jianbo xiao Hui cao Zhiyong Chen Huifan Liu Yuanqing Gao hongxun Tao Key Laboratory of Cardiovascular and Cerebrovascular Medicine School of PharmacyNanjing Medical UniversityNanjing 211166China School of Food and Biological Engineering Jiangsu UniversityZhenjiang 212013China Department of Analytical Chemistry and Food Science Faculty of ScienceUniversity of VigoVigo 36310Spain CISPAC Fontan BuildingCity of CultureSantiago de Compostela 15707Spain Shaanxi Academy of Traditional Chinese Medicine Xi'an 710003China Guangdong Key Laboratory of Science and Technology of Lingnan Specialty Food Zhongkai University of Agriculture and EngineeringGuangzhou 510550China State Key Laboratory of Southwestern Chinese Medicine Resources Chengdu 610075China

Rhodiola crenulate is the edible medicinal herbal medicine widely used for altitude sickness in ***,our previous work has found that *** extract(RCE)could significantly improve the pathology associated with dextran sulfate sodium-induced ***,the current research aims to reveal the pharmacodynamic material basis of RCE,as well as its mechanism against *** chemical characterization of RCE was performed by UHPLC-HR-MS,through which a total of 88 constituents were ***,our results also found 29 constituents absorbed into blood and 8 metabolized absorbable *** decreased flavonoids prototype and the elevated sulfated products of phenols were observed under pathophysiological conditions of *** metabolomics study revealed that colitis caused the alternation of fatty acid metabolism,steroid hormone biosynthesis and bile acid ***,RCE could prevent colitis by improving fatty acid metabolism and secondary bile acid metabolism.

关键词： Rhodiola crenulate Colitis Chemical characterization Plasma pharmacochemistry Metabolomics

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A-Weyl定理及其摄动

数学学报（中文版） 2017年第6期60卷 1013-1024页

作者：董炯曹小红刘俊慧陕西师范大学数学与信息科学学院西安710119

本文讨论了本质逼近点谱的一种变形,并利用该变形定义的新的谱集,研究了α-Weyl定理在紧摄动下的稳定性.同时,给出了对任意的正整数n∈N,算子T^n∈B(H)不满足α-Weyl定理的稳定性的充分条件,其中H表示无限维的复可分Hilbert空间,B(H)表... 详细信息

本文讨论了本质逼近点谱的一种变形,并利用该变形定义的新的谱集,研究了α-Weyl定理在紧摄动下的稳定性.同时,给出了对任意的正整数n∈N,算子T^n∈B(H)不满足α-Weyl定理的稳定性的充分条件,其中H表示无限维的复可分Hilbert空间,B(H)表示H上的有界线性算子的全体.

关键词： a—Weyl定理谱摄动

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上三角算子矩阵的单值延拓性质的摄动

数学学报（中文版） 2016年第4期59卷 451-460页

作者：曹小红吴学俪张敏陕西师范大学数学与信息科学学院西安710062

设H为无限维可分的复Hilbert空间,B(H)为H上的有界线性算子全体.算子T∈B(H)称为具有单值延拓性质,若对任意一个开集U(?)C,满足方程(T-λI)f(λ)=0(任给λ∈U)的唯一的解析函数f:U→H为零函数;T∈B(H)称为满足单值延拓性质的稳定性,若... 详细信息

设H为无限维可分的复Hilbert空间,B(H)为H上的有界线性算子全体.算子T∈B(H)称为具有单值延拓性质,若对任意一个开集U(?)C,满足方程(T-λI)f(λ)=0(任给λ∈U)的唯一的解析函数f:U→H为零函数;T∈B(H)称为满足单值延拓性质的稳定性,若对任意一个紧算子K∈B(H),T+K都满足单值延拓性质.本文给出了2×2上三角算子矩阵在紧摄动下满足单值延拓性质的稳定性的特征.

关键词：单值延拓性质紧摄动谱

Identification of marker genes associated with N6-methyladenosine and autophagy in ulcerative colitis

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World Journal of Clinical Cases 2024年第10期12卷 1750-1765页

作者： xiao-Yan Liu Dan Qiao Ya-Li Zhang Zi-Xuan Liu You-Lan Chen Ren-Ye Que hong-Yan cao Yan-Cheng Dai Department of Gastroenterology Shanghai Traditional Chinese Medicine-Integrated HospitalShanghai University of Traditional Chinese MedicineShanghai 200082China Institute of Digestive Diseases Long Hua Hospital Shanghai University of Traditional Chinese MedicineShanghai 200032China Department of Gastroenterology Shu Guang HospitalShanghai University of Traditional Chinese MedicineShanghai 201203China

BACKGROUND Both N6-methyladenosine(m6A)methylation and autophagy are considered relevant to the pathogenesis of ulcerative colitis(UC).However,a systematic exploration of the role of the com-bination of m6A methylation and autophagy in UC remains to be *** To elucidate the autophagy-related genes of m6A with a diagnostic value for *** The correlation between m6A-related genes and autophagy-related genes(ARGs)was ***,gene set enrichment analysis(GSEA)was performed on the characteristic ***,the expression levels of four characteristic genes were verified in dextran sulfate sodium(DSS)-induced colitis in *** GSEA indicated that BAG3,P4HB and TP53INP2 were involved in the inflammatory response and TNF-αsignalling via nuclear factor ***,polymerase chain reaction results showed significantly higher mRNA levels of BAG3 and P4HB and lower mRNA levels of FMR1 and TP53INP2 in the DSS group compared to the control *** This study identified four m6A-ARGs that predict the occurrence of UC,thus providing a scientific reference for further studies on the pathogenesis of UC.

关键词： Ulcerative colitis m6A Autophagy Characteristic genes Immune infiltration

Service Function Chain Migration in LEO Satellite Networks

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China Communications 2024年第3期21卷 247-259页

作者： Geng Yuhui Wang Niwei Chen Xi Xu xiaofan Zhou Changsheng Yang Junyi xiao Zhenyu cao Xianbin School of Electronic and Information Engineering Beihang UniversityBeijing 100191China Key Laboratory of Advanced Technology of Near Space Information System Ministry of Industry and Information Technology of ChinaBeijing 100191China Shanghai Key Laboratory of Satellite Network Shanghai 201204China Shanghai Satellite Network Research Institute Co. Ltd.Shanghai 201204China

With the advancements of software defined network(SDN)and network function virtualization(NFV),service function chain(SFC)placement becomes a crucial enabler for flexible resource scheduling in low earth orbit(LEO)satellite *** due to the scarcity of bandwidth resources and dynamic topology of LEO satellites,the static SFC placement schemes may cause performance degradation,resource waste and even service *** this paper,we consider migration and establish an online migration model,especially considering the dynamic *** the scarcity of bandwidth resources,the model aims to maximize the total number of accepted SFCs while incurring as little bandwidth cost of SFC transmission and migration as *** to its NP-hardness,we propose a heuristic minimized dynamic SFC migration(MDSM)algorithm that only triggers the migration procedure when new SFCs are *** results demonstrate that MDSM achieves a performance close to the upper bound with lower complexity.

关键词： network function virtualization(NFV) resource allocation satellite networks service function chain(SFC) SFC migration SFC placement soft-ware defined network(SDN)