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快速获得7055铝合金淬火敏感温度区间的新方法及机理

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Transactions of Nonferrous Metals Society of China 2023年第1期33卷 36-45页

作者：盛晓菲贺存孝程亚娟饶晓晓何国爱中南大学材料科学与工程学院长沙410083 湖北汽车工业学院材料科学与工程学院十堰442002 中南大学轻合金研究所长沙410083 中南大学高性能复杂制造国家重点实验室长沙410083 广州大学物理与材料科学学院广州510006

采用一种省时、节约资源的变温热处理(ATHT)新方法,基于硬度与电导率,获得喷射沉积7055铝合金的淬火敏感温度区间。此外,通过透射电子显微镜(TEM)表征ATHT期间的显微组织演变。研究表明,7055合金的ATHT是一个溶质原子随着温度的升高而... 详细信息

采用一种省时、节约资源的变温热处理(ATHT)新方法,基于硬度与电导率,获得喷射沉积7055铝合金的淬火敏感温度区间。此外,通过透射电子显微镜(TEM)表征ATHT期间的显微组织演变。研究表明,7055合金的ATHT是一个溶质原子随着温度的升高而析出和再溶解的过程。当温度达到200℃时,合金的硬度急剧增加,电导率适当增加。随着温度升高到400℃以上,电导率从峰值迅速下降,表明溶质原子回溶加速,同时,在基体内η’强化相逐渐转变成η平衡相。通过对硬度曲线和电导率曲线的分析,得出当前合金淬火敏感性温度范围为200~400℃,这与传统分级保温法测得的结果一致。

关键词：铝合金变温热处理淬火敏感温度区间显微组织演变

Mining Cluster-Defining Actionable Rules

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Mining Cluster-Defining Actionable Rules

miRNA-21-5p is an important contributor to the promotion of injured peripheral nerve regeneration using hypoxia-pretreated bone marrow-derived neural crest cells

第二十一届中国数据库学术会议

作者： HE Zeng-You XU xiao-fei DENG sheng-Chun (Department of Computer Science and Engineering,Harbin Institute of Technology,Harbin 150001)

One of the main motivations of clustering has been the hope that,by clustering the data in meaningfully distinct clusters,we can then proceed to make independent decisions for each *** paper develops two frameworks,Loose-Coupled Framework and Tight-Coupled Framework,for evaluating clustering methods in terms of their value in *** specified,we use the contrast set mining technique to mine cluster-defining actionable rules from data clusters to understand the differences between *** an experimental study we demonstrate the usefulness of our techniques against other popular *** technique has potential applications in CRM such as designing different marketing campaigns for various customer segmentations.

关键词： Clustering Contrast set Actionable rules Data mining

来源： cnki会议评论

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Neural Regeneration Research 2025年第1期20卷 277-290页

作者： Meng Cong Jing-Jing Hu Yan Yu xiao-Li Li xiao-Ting Sun Li-Ting Wang Xia Wu Ling-Jie Zhu xiao-Jia Yang Qian-Ru He fei Ding Hai-Yan Shi School of Medicine Nantong UniversityNantongJiangsu ProvinceChina Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education and Coinnovation Center of Neuroregeneration Nantong UniversityNantongJiangsu ProvinceChina Department of Physiology Jiangsu Health Vocational CollegeNanjingJiangsu ProvinceChina Department of Pathology Affiliated Hospital of Nantong UniversityNantongJiangsu ProvinceChina Jiangsu Clinical Medicine Center of Tissue Engineering and Nerve Injury Repair Affiliated Hospital of Nantong UniversityNantongJiangsu ProvinceChina

Our previous study found that rat bone marrow–derived neural crest cells(acting as Schwann cell progenitors)have the potential to promote long-distance nerve ***-based therapy can enhance peripheral nerve repair and regeneration through paracrine bioactive factors and intercellular ***,the complex contributions of various types of soluble cytokines and extracellular vesicle cargos to the secretome remain *** investigate the role of the secretome and extracellular vesicles in repairing damaged peripheral nerves,we collected conditioned culture medium from hypoxia-pretreated neural crest cells,and found that it significantly promoted the repair of sensory neurons damaged by oxygen-glucose *** mRNA expression of trophic factors was highly expressed in hypoxia-pretreated neural crest *** performed RNA sequencing and bioinformatics analysis and found that miR-21-5p was enriched in hypoxia-pretreated extracellular vesicles of neural crest ***,to further clarify the role of hypoxia-pretreated neural crest cell extracellular vesicles rich in miR-21-5p in axonal growth and regeneration of sensory neurons,we used a microfluidic axonal dissociation model of sensory neurons in vitro,and found that hypoxia-pretreated neural crest cell extracellular vesicles promoted axonal growth and regeneration of sensory neurons,which was greatly dependent on loaded ***,we constructed a miR-21-5p-loaded neural conduit to repair the sciatic nerve defect in rats and found that the motor and sensory functions of injured rat hind limb,as well as muscle tissue morphology of the hind limbs,were obviously *** findings suggest that hypoxia-pretreated neural crest extracellular vesicles are natural nanoparticles rich in ***-21-5p is one of the main contributors to promoting nerve regeneration by the neural crest cell *** helps to explain the mechanism of action of the secretome and e

关键词： axotomy cell-free therapy conditioned medium extracellular vesicles hypoxic preconditioning microRNA oxygen-glucose deprivation peripheral nerve injury Schwann cell precursors

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不同贮藏温度对肉制品中亚硝酸盐含量的影响

食品研究与开发 2017年第1期38卷 139-141页

作者：帅瑾吕晓飞刘胜男焦肖飞巩卫东三门峡市检验检疫中心河南三门峡472000 三门峡出入境检验检疫局河南三门峡472000

本文研究不同贮藏条件对腊肉、香肠、火腿肠、西式火腿和熏烤肉中亚硝酸盐含量的影响。比较了5种肉制品在冷冻(-18℃)、冷藏(4℃)、常温(25℃)条件下贮藏时,其亚硝酸盐的含量随着贮藏时间的变化趋势。结果表明:随着贮藏时间的延长,肉制... 详细信息

本文研究不同贮藏条件对腊肉、香肠、火腿肠、西式火腿和熏烤肉中亚硝酸盐含量的影响。比较了5种肉制品在冷冻(-18℃)、冷藏(4℃)、常温(25℃)条件下贮藏时,其亚硝酸盐的含量随着贮藏时间的变化趋势。结果表明:随着贮藏时间的延长,肉制品中的亚硝酸盐含量呈下降趋势,且室温条件下亚硝酸盐的含量比冷藏低,冷藏条件下的亚硝酸盐含量比冷冻低。

关键词：肉制品亚硝酸盐残留量贮藏温度

高校教育游戏研发团队建设的研究——以浙江师范大学教育游戏研发基地为例

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宁波大学学报（教育科学版） 2008年第5期30卷 94-97页

作者：肖飞生章苏静浙江师范大学教师教育学院浙江金华321004

通过团队建设实践的视角,整合管理学和心理学有关知识,在行动中研究基地研发团队建设的规律和特点——将团队定位为非正式的学习型、实践共同体,通过信息化协作平台和社会性软件对团队进行信息化管理,利用大学生多媒体作品设计竞赛的良... 详细信息

通过团队建设实践的视角,整合管理学和心理学有关知识,在行动中研究基地研发团队建设的规律和特点——将团队定位为非正式的学习型、实践共同体,通过信息化协作平台和社会性软件对团队进行信息化管理,利用大学生多媒体作品设计竞赛的良好评价机制以及精神和物质激励,引导团队健康发展,并通过有组织招募与个人招募相结合来优化团队建设。

关键词：教育游戏研发团队团队建设实践共同体学习型团队

高铁对贵阳市经济发展影响的作用机制和经济效应分析

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江苏商论 2017年第8期 60-64页

作者：肖远飞石胜民昆明理工大学管理与经济学院云南昆明650093

近年来,高铁由于其在省际和城际交通运输体系中不可替代的优势在我国铁路建设中开始崛起,截至2016年底,我国高铁总运营里程超过2.2万公里,占全国铁路总营运里程的17.74%。高铁建设作为一项重大的民生工程必然会对沿线地区的经济发展产... 详细信息

近年来,高铁由于其在省际和城际交通运输体系中不可替代的优势在我国铁路建设中开始崛起,截至2016年底,我国高铁总运营里程超过2.2万公里,占全国铁路总营运里程的17.74%。高铁建设作为一项重大的民生工程必然会对沿线地区的经济发展产生重要影响,文章选取贵阳市作为研究对象,从高铁影响地区经济发展的作用机制和产生的经济效应两方面就高铁对贵阳市经济发展的影响进行分析。

关键词：高铁贵阳市作用机制经济效应

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流水式转向灯设计方案研究

汽车电器 2020年第7期 59-60,63页

作者：肖星肖飞胜卢生林徐青张宜勇奇瑞汽车股份有限公司安徽芜湖241009

本文通过研究行业背景,对汽车行业内转向灯的工作模式、法律法规等基本信息进行分析,研究实现流水式转向灯功能的设计方案,该方案(本文指多颗LED的电路设计控制方案)主要通过驱动电路控制单颗光源的亮灭,实现客观上的"流水"点亮效果。... 详细信息

本文通过研究行业背景,对汽车行业内转向灯的工作模式、法律法规等基本信息进行分析,研究实现流水式转向灯功能的设计方案,该方案(本文指多颗LED的电路设计控制方案)主要通过驱动电路控制单颗光源的亮灭,实现客观上的"流水"点亮效果。此方案仅供参考,对于未来流水式转向灯的产品设计,可结合功能、成本、性能及周边环境等综合考虑。

关键词：流水式转向灯分析方案

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大数据时代公共管理的挑战及创新模式探究

安徽理工大学学报（社会科学版） 2016年第5期18卷 11-15页

作者：张小红费保升方海张栋安徽理工大学人文与社会科学学院安徽淮南232001

随着计算机技术与数据分析技术的迅猛发展,大数据作为数据资源与信息资本对公共管理创新产生重大影响,精准化的公共管理模式应运而生。大数据技术为提升公共管理的科学决策水平、服务能力、满足民众个性化需求以及提升社会风险管理能力... 详细信息

随着计算机技术与数据分析技术的迅猛发展,大数据作为数据资源与信息资本对公共管理创新产生重大影响,精准化的公共管理模式应运而生。大数据技术为提升公共管理的科学决策水平、服务能力、满足民众个性化需求以及提升社会风险管理能力提供了机遇,但也面临着大数据意识缺乏、信息安全、信息孤岛、人才匮乏等一系列挑战。应树立大数据思维意识,建构以大数据为中心,以政府为主导,企业、社会组织、普通民众等主体协同合作进行精准化管理的新模式。

关键词：大数据时代公共管理机遇挑战精准化管理

Activation of NKT Cells by IL-15 Plus GM-CSF Stimulation and Its Cytotoxicity to Neuroblastoma Cells

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中国当代儿科杂志 2002年第4期4卷 342-344页

作者： LIU Li Zhen, TANG Suo Qin, ZHANG xiao fei, HUANG Dong sheng, WANG Jian Wen(Department of Pediatrics, People’s Liberation Army General Hospital, Beijing 100853, China)

Objective To study if IL 15 or GM CSF, or their combination can activate NKT cells from the normal childhood peripheral blood; and if activated NKT cells can kill neuroblastoma cells. Methods T cells obtained from the normal childhood peripheral blood were activated by stimulation under IL 15 alone or GM CSF alone, or their combination. The proliferation of T cells was measured by MTT methods. NKT cells were identified and isolated on the basis of surface phenotype by two color flow cytometry. Cytotoxicity on neuroblastoma cell line LA N 6 mediated by NKT cells was investigated. Results The proliferation of T cells in the IL 15, GM CSF stimulation group and the combination group was higher than the non stimulated controls ( 1.25 fold, 1.2 fold, 1.4 fold, respectively; all P< 0.01 ); the surface antigen expression of NKT cells was up regulated compared with the controls (2.56 fold, 3.27 fold, 4.39 fold, respectively; P< 0.01 or <0.05 ). The cytotoxicity of NKT cells stimulated by GM CSF alone or by IL 15 plus GM CSF was enhanced compared with the controls (P< 0.01 ). There was no difference in the cytotoxicity between the IL 15 stimulation group and the controls. The proliferation of T cells was enhanced in the IL 15 plus GM CSF stimulation group compared with the GM CSF stimulation group; but there was no difference in the surface antigen expression and the cytotoxicity of NKT cells between the two experimental groups. The surface antigen expression and the cytotoxicity of NKT cells were higher in the IL 15 plus GM CSF stimulation group compared with the IL 15 stimulation group; but there was no difference in the proliferation of T cells between the two experimental groups. There was no difference in the proliferation of T cells, the surface antigen expression and the cytotoxicity of NKT cells between the IL 15 and GM CSF stimulation groups, either. Conclusions IL 15 and GM CSF could induce the proliferation of NKT cells of normal children and enhance its func

关键词： NKT cell IL 15 GM CSF Neuroblastoma