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Three-stage niobium mineralization at Bayan Obo, China

National Science Review 2024年第4期11卷 102-110页

作者： Yan Yu Yang Li Yu Liu xiao-xiao Ling Li-Guang wu Li Yang Lan Yang Bo Yang Yong-Gang Zhao Xian-Hua Li State Key Laboratory of Lithospheric Evolution Institute of Geology and Geophysics Chinese Academy of Sciences College of Earth and Planetary Science University of Chinese Academy of Sciences Ministry of Education Key Laboratory of Orogenic Belts and Crustal Evolution School of Earth and Space SciencesPeking University Mining Research Institute Baotou Iron and Steel(Group) Co.LTD State Key Laboratory of Baiyunobo Rare Earth Resource Research and Comprehensive Utilization

The Chinese Bayan Obo deposit is a world-class rare earth element(REE) deposit with considerable niobium(Nb) and iron(Fe) resources. A complete genetic understanding on all metals is fundamental for establishing genetic models at Bayan Obo. With extensive research being focused on REE enrichment, the timing and controls of Nb enrichment remain unresolved at Bayan Obo, which is mainly due to the challenges in dating, i.e. multistage thermal events, fine-grained minerals with complex textures and the rare occurrence of uranium-enriched minerals with mature dating methods. Based on robust geological and petrographic frameworks, here we conducted ion probe uranium-lead(U-Pb) dating of ferrocolumbite to unravel the timing, hence the genesis of Nb mineralization. Three types of hydrothermal ferrocolumbites—key Nb-bearing minerals—are identified based on their textures and mineral assemblages. They yield U-Pb ages of 1312 ± 47 Ma(n = 99), 438 ± 7 Ma(n = 93), and 268 ± 5 Ma(n = 19), respectively. In line with deposit geology, we tentatively link the first, second and third stage Nb mineralization to Mesoproterozoic carbonatite magmatism, ubiquitous early Paleozoic hydrothermal activity, and Permian granitic magmatism, respectively. While quantifying the contribution of metal endowment from each stage requires further investigation, our new dates highlight that multi-stage mineralization is critical for Nb enrichment at Bayan Obo, which may also have implications for the enrichment mechanism of Nb in REE deposits in general.

关键词： niobium mineralization U-Pb dating ferrocolumbite Bayan Obo

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Single-element amorphous metals

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Interdisciplinary Materials 2024年第4期3卷 480-491页

作者： xiao Han Geng wu Dong Sheng He Xun Hong Center of Advanced Nanocatalysis(CAN) Department of Applied ChemistryHefei National Research Center for Physical Sciences at the MicroscaleUniversity of Science and Technology of ChinaHefeiAnhuiChina Core Research Facilities Southern University of Science and TechnologyShenzhenChina

To unveil the nature of amorphous states,single-element amorphous metals have been the perfect research subject due to the simplest ***,the extreme crystal nucleation and growth rate in single-element metal make the synthesis of single-element amorphous metals seemingly impossible in the ***,benefited by several delicate synthetic strategies developed recently,the single-element amorphous metals have been successfully *** review aims to provide a systematic overview of the synthesis of single-element amorphous metals covering the challenges in physics and recent *** addition,current understanding of the atomic and electronic structures of single-element amorphous metal has also been ***,the challenges that worth further investigation are *** identifying the potential avenues for further exploration,this review aims to contribute valuable insights that will propel the cognition of single-element amorphous metals.

关键词： amorphous metal single-element structure synthesis

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dietary inflammatory index and its impact on severity and recurrence of Tourette syndrome in children

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World Journal of Psychiatry 2024年第8期14卷 1208-1215页

作者： xiao-Ping wu Rong-Rong Fang Ting-Ting Ji Department of Pediatrics Qingdao Chengyang People’s HospitalQingdao 266109Shandong ProvinceChina

BACKGROUND Tourette syndrome(TS)is a neurodevelopmental disorder characterized by the presence of motor and vocal tics,typically beginning in *** signifi-cant research efforts,the exact pathophysiology of TS remains incompletely *** studies suggest that inflammation may play a role in the severity and progression of TS,pointing to the potential influence of dietary and lifestyle factors on the ***,research on the specific connection between dietary inflammatory index(diI)and TS is still in its early stages,requir-ing additional clinical and epidemiological studies to validate the strength and specific mechanisms of this *** A total of 207 children diagnosed with TS in the pediatric department of Qingdao Chengyang People’s Hospital from January 2022 to January 2023 were *** were divided into stable and unstable groups based on follow-up *** enrollment,general information of the children[age,gender,body mass index(BMI),guardian’s education level,diI score,medical history,family history,academic stress,electronic device usage,medication,and disease progression]was assessed,and serum inflammatory levels were measured during follow-up *** scores and Yale Global Tic Severity Scale(YGTSS)scores were ***,based on YGTSS scores,the children were classified into mild,moderate,and severe *** diI,interleukin-6(IL-6),C-reactive protein(CRP),and tumor necrosis factor-alpha(TNF-α)levels in each group were *** Follow-up surveys were completed by 207 children and their *** them,117 children were in the stable group,and 90 were in the recurrent *** found no statistically significant differences in age,gender,comorbidities,BMI,and disease duration between the two groups(P>0.05).However,academic stress,electronic device usage,medication,guardian’s education level,and diI scores showed statistically significant differences between the groups(P

关键词： dietary inflammation index Tourette's syndrome Correlation analysis Pro-inflammatory foods Inflammation levels Impact on severity and recurrence

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Supersaturation-driven self-assembly formation of ceftriaxone sodium spherulites:From amorphous form to spherulites

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Particuology 2024年第7期90卷 10-19页

作者： Shankun Liang Yuchao Niu Xueyan Hu wu xiao Xuehua Ruan Gaohong He xiaobin Jiang State Key Laboratory of Fine Chemicals Frontiers Science Center for Smart MaterialsSchool of Chemical EngineeringDalian University of TechnologyDalian116024China School of Chemical Engineering at Panjin Dalian University of TechnologyPanjin124221China

Drug particles with spherical morphology possess amazing advantages in terms of particle flowability,mechanical properties,drug solubility,and *** growth mechanism of drug spherulite is of great importance for the preparation and regulation of ***,ceftriaxone sodium spherulites were fabricated by the antisolvent crystallization method using dropwise addition of ceftriaxone sodium solution to *** observation of the whole crystallization process combined with electron microscopy technique revealed the spherical growth process from amorphous form to *** the supersaturation of the crystallization system was adjusted,the ceftriaxone sodium crystals transformed from amorphous form to *** the process of antisolvent crystallization with acetone as antisolvent,when the theoretical supersaturation degree S was higher than 2.62,the crystallization system tended to appear amorphous form;when S was between 2.57 and 2.62,the amorphous form transformed into clustered spherulites;when S was less than 2.57,the surface of spherulites will be covered with flaky crystal,which transformed into urchin-like *** the understanding of the spherical growth mechanism,the ceftriaxone sodium spherulites prepared in this research with modified supersaturation control had a low residue of antisolvent acetone,and the flowability was significantly improved.

关键词： Spherulite Ceftriaxone sodium Antisolvent crystallization Supersaturation Online observation

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Major royal-jelly proteins intake modulates immune functions and gut microbiota in mice

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Food Science and Human Wellness 2024年第1期13卷 444-453页

作者： Hang wu Shican Zhou Wenjuan Ning xiao wu xiaoxiao Xu Zejin Liu Wenhua Liu Kun Liu Lirong Shen Junpeng Wang Infection and Immunity Institute and Translational Medical Center of Huaihe Hospital Henan UniversityKaifeng 475000China College of Biology Science and Engineering Hebei University of Economics and BusinessShijiazhuang 050061China College of Biosystems Engineering and Food Science Zhejiang Key Laboratory for Agro-Food ProcessingZhejiang UniversityHangzhou 310058China

In this study,we investigated the effects of major royal jelly proteins(MRJPs)on the estrogen,gut microbiota,and immunological responses in *** given 250 or 500 mg/kg,not 125 mg/kg of MRJPs,enhanced the proliferation of splenocytes in response to *** splenocytes and mesenteric lymphocytes activated by T-cell mitogens(Con A and anti-CD3/CD28 antibodies)released high levels of IL-2 but low levels of IFN-γand *** release of IL-4 was unaffected by ***,splenocytes and mesenteric lymphocytes activated by LPS were prevented by MRJPs at the same dose as that required for producing IL-1βand IL-6,two pro-inflammatory *** production of IL-1β,IL-6,and IFN-γwas negatively associated with estrogen levels,which were higher in the MRJP-treated animals than in the control *** of the gut microbiota revealed that feeding mice 250 mg/kg of MRJPs maintained the stability of the natural intestinal microflora of ***,the LEf Se analysis identified biomarkers in the MRJP-treated mice,including Prevotella,Bacillales,Enterobacteriales,Gammaproteobacteria,Candidatus_Arthromitus,and *** results showed that MRJPs are important components of royal jelly that modulate host immunity and hormone levels and help maintain gut microbiota stability.

关键词： Major royal-jelly proteins Immunity Estrogen Gut microbiota Cytokines

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dietary curcumin alleviates intestinal damage induced by ochratoxin A in juvenile grass carp(Ctenopharyngodon idella):Necroptosis and inflammatory responses

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Animal Nutrition 2024年第3期18卷 119-132页

作者： Piao Zhao Wei Dan Jiang Pei wu Yang Liu Hong Mei Ren xiao Wan Jin Lin Feng xiao Qiu Zhou Animal Nutrition Institute Sichuan Agricultural UniversityChengdu 611130SichuanChina Fish Nutrition and Safety Production University Key Laboratory of Sichuan Province Sichuan Agricultural UniversityChengdu 611130SichuanChina Key Laboratory of Animal disease-Resistance Nutrition Ministry of EducationMinistry of Agriculture and Rural AffairsKey Laboratory of Sichuan ProvinceSichuan611130China

Ochratoxin A(OTA)is one of the most common pollutants in aquatic *** a first line of defense,intestinal barriers could be utilized against OTA in order to prevent *** product supplementation is one of the most popular strategies to alleviate toxicity induced by mycotoxins,but there is a lack of knowledge about how it functions in the teleost *** this study,720 juvenile grass carp of about 11 g were selected and four treatment groups(control group,OTA group,curcumin[Cur]group,and OTA+Cur group)were set up to conduct a 60-day growth *** the test,the growth performance and intestinal health related indexes of grass carp were *** addition of dietary Cur could have the following main results:(1)inhibit absorption and promote efflux transporters mRNA expression,reducing the residuals of OTA,(2)decrease oxidative stress by reducing oxidative damage and enhancing the expression of antioxidant enzymes,(3)promote mitochondrial fusion proteins to inhibit the expression of mitotic proteins and mitochondrial autophagy proteins and enhance mitochondrial function,(4)reduce necroptosis-related gene expression through inhibiting the tumor necrotic factor receptor-interacting protein kinase/mixed lineage kinase domain-like pathway,(5)reduce the expression of pro-inflammatory factors by inhibiting the Toll-like receptor 4/nuclear factor-κB signaling pathway to alleviate the intestinal inflammatory *** summary,the results suggested that Cur could alleviate OTA-induced intestinal damage by enhancing antioxidant capacity and mitochondrial function as well as reducing necroptosis and inflammation in the grass carp *** study provided a theoretical basis and production implications for dietary Cur that could improve growth performance and alleviate the intestinal damage induced by OTA in fish.

关键词： Curcumin Ochratoxin A Grass carp growth performance Mid-intestine mitochondria function Necroptosis

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Research progress and challenges in stem cell therapy for diabetic foot: Bibliometric analysis and perspectives

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World Journal of Stem Cells 2024年第1期16卷 33-53页

作者： Hong-Shuo Shi Xin Yuan Fang-Fang wu xiao-Yu Li Wei-Jing Fan xiao Yang xiao-Ming Hu Guo-Bin Liu Department of Peripheral Vascular Surgery Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese MedicineShanghai 250021China

BACKGROUND Stem cell therapy has shown great potential for treating diabetic foot(DF).AIM To conduct a bibliometric analysis of studies on the use of stem cell therapy for DF over the past two decades,with the aim of depicting the current global research landscape,identifying the most influential research hotspots,and providing insights for future research *** We searched the Web of Science Core Collection database for all relevant studies on the use of stem cell therapy in *** analysis was carried out using CiteSpace,VOSviewer,and R(4.3.1)to identify the most notable *** A search was conducted to identify publications related to the use of stem cells for DF treatment.A total of 542 articles published from 2000 to 2023 were *** United States had published the most papers on this *** this field,Iran’s Shahid Beheshti University Medical Sciences demonstrated the highest ***,*** from the same university has been an outstanding researcher in this *** Cell Research&Therapy is the journal with the highest number of publications in this *** main keywords were“diabetic foot ulcers,”“wound healing,”and“angiogenesis.”CONCLUSION This study systematically illustrated the advances in the use of stem cell therapy to treat DF over the past 23 *** research findings suggested that the hotspots in this field include stem cell dressings,exosomes,wound healing,and adipose-derived stem *** research should also focus on the clinical translation of stem cell therapies for DF.

关键词： Stem cells diabetic foot Bibliometric CiteSpace VOSviewer R-bibliometrix

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A Research Progress of CO_(2)-Responsive Plugging Channeling Gels

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Energy Engineering 2024年第7期121卷 1759-1780页

作者： Yang Xiong Jianxin Liu Xianhao Yi Bangyan xiao Dan wu Biao wu Chunyu Gao Key Laboratory of Drilling and Production Engineering for Oil and Gas Yangtze UniversityWuhan430100China School of Petroleum Engineering Yangtze UniversityWuhan430100China

In the heterogeneous reservoirs,CO_(2) flooding easily leads to CO_(2) gas channeling,which can seriously affect sweeping efficiency and reduce oil *** thoroughly investigating the advantages and shortcomings of various CO_(2) plugging technologies,this paper focuses on the feasibility of improving conventional water-alternating gas(WAG)through CO_(2)-responsive gel *** on the different chemical reaction mechanisms between the unique chemical structure and CO_(2),changes in the material’s physical and chemical properties can respond to CO_(2).The feasibility of utilizing these property changes for CO_(2)-responsive plugging is *** CO_(2)-responsive gels and gel nanoparticles have been extensively researched in different fields,such as energy,medicine,and *** paper surveys the molecular structures,chemical compositions,response mechanisms,and changes of these CO_(2)-responsive gels,aiming to draw insights into the carbon dioxide-enhanced oil recovery(CO_(2)-EOR)***,the key issues and future development direction of CO_(2)-responsive plugging gels were analyzed.

关键词： Gas channeling sweep efficiency CO_(2)-responsive gel CO_(2)-EOR

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Study of the Lift Force Induced by An Interceptor on A High-Speed Mono-Hull:The Affecting Factors and Estimation Formula

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China Ocean Engineering 2024年第4期38卷 557-571页

作者： DENG Rui HU Yu-xiao HUANG Si-chong SONG Zhi-jie WANG Shi-gang wu Tie-cheng School of Ocean Engineering and Technology Sun Yat-sen Universityand Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai)Zhuhai 519082China

To find a better way to estimate the lift force induced by an interceptor on a high-speed mono-hull ship,a series of high-speed mono-hull ship models are designed and investigated under different *** lift forces are obtained by numerical calculations and validated by a model test in a towing *** factors that influence the force are the interceptor height,velocity,draft,and deadrise *** relationship between each factor and the induced lift force is investigated and *** found that the induced lift mainly depends on the interceptor height and advancing velocity,and is proportional to the square of the interceptor height and *** results also showed that the effects of the draft and deadrise angle are relatively less important,and the relationship between the induced lift and these two factors is generally *** on the results,a formula including the combined effect of all factors used to estimate the lift force induced by the interceptor is developed based on systematic *** proposed formula could be used to estimate the lift force induced by interceptors,especially under high-speed condition.

关键词： high-speed mono-hull ship interceptor lift force formula lift force towing tank test computational fluid dynamics

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微细通道内纳米制冷剂的流动沸腾传热特性

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华南理工大学学报（自然科学版） 2016年第8期44卷 1-7页

作者：罗小平吴迪冯振飞涂华营华南理工大学机械与汽车工程学院广东广州510640 广西大学化学化工学院广西南宁530004

分别以0、0.031%、0.062%、0.155%、0.248%浓度的Al_2O_3-R141b纳米制冷剂为工质,在水力直径为1.33 mm的矩形铝基微细通道内进行了流动沸腾实验,研究了不同浓度纳米制冷剂实验后槽道表面能的变化情况.结果表明:加入少量纳米颗粒后,壁面... 详细信息

分别以0、0.031%、0.062%、0.155%、0.248%浓度的Al_2O_3-R141b纳米制冷剂为工质,在水力直径为1.33 mm的矩形铝基微细通道内进行了流动沸腾实验,研究了不同浓度纳米制冷剂实验后槽道表面能的变化情况.结果表明:加入少量纳米颗粒后,壁面形成大量的活化核心,使得沸腾起始点ONB提前,强化了传热;浓度为0.062%纳米制冷剂的强化传热效果最好,传热系数比纯制冷剂最大可提高48.1%;当纳米颗粒浓度超过最佳浓度而继续增大时,颗粒在表面沉积现象越来越严重,使槽道表面能增大,换热热阻也随之增大,强化传热效果反而依次降低.浓度为0.031%、0.062%、0.155%、0.248%纳米制冷剂实验后的槽道表面能,比槽道原始表面能分别增长了0.47、1.39、1.89、2.14倍.

关键词：微细通道纳米制冷剂强化传热表面能

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