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Primitive neuroectodermal tumor of the prostate in a 58-year-old man:A case report

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World Journal of Clinical Cases 2022年第13期10卷 4145-4152页

作者： Da-Wei Tian xiao-chun wang Hui Zhang Yan Tan College of Medical Imaging Shanxi Medical UniversityTaiyuan 030001Shanxi ProvinceChina Department of Radiology The First Hospital of Shanxi Medical UniversityTaiyuan 030001Shanxi ProvinceChina

BACKGROUND Primitive neuroectodermal tumor(PNET),especially located in the prostate,is a rare tumor that mainly occurs in young *** or rectum invasion and distant metastasis are strongly associated with a poor *** therapy,including radical surgery,adjuvant chemotherapy,and radiotherapy,is *** present a case of prostatic PNET and a review of 17 cases identified in the *** SUMMARY A 58-year-old man was admitted complaining of dysuria for 2 *** tomography and magnetic resonance imaging showed a large cystic-solid mass in the pelvic cavity compressing the surrounding bladder and *** mass was iso-to hyperintense on T1-weighted imaging(WI)and heterogeneously hyperintense on *** degeneration and necrosis were seen in the tumor,and solid tissues within the mass enhanced on contrast-enhanced *** patient underwent robot-assisted laparoscopic pelvic tumor ***,the presence of many small round cells that were positive for expression of CD99,vimentin,and synaptophysin established the diagnosis of PNET in the prostate after *** patient underwent adjuvant *** 34 mo of follow-up,the patient had no signs or symptoms of recurrence or residual *** We present the case of the oldest prostatic PNET patient,who has a good *** illustrates how older men with prostatic PNET may also benefit from the combination therapy,like younger adults,and achieve a long-term *** always,PNET should be considered in the differential diagnosis of aggressive prostatic tumors in young men.

关键词： Primitive neuroectodermal tumor Prostate Combination therapy Magnetic resonance imaging CD99 Case report

Cutaneous allergic reaction to subcutaneous vitamin K_(1):A case report and review of literature

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World Journal of Clinical Cases 2022年第29期10卷 10742-10754页

作者： Miao Zhang Jia Chen chun-xiao wang Nai-Xuan Lin Xin Li Department of Dermatology Yueyang Hospital of Integrated Traditional Chinese and Western MedicineShanghai University of Traditional Chinese MedicineShanghai 200437China Institute of Dermatology Shanghai Academy of Traditional Chinese MedicineShanghai 201203China Department of Dermatopathology Shanghai Skin Disease HospitalTongji UniversityShanghai 200443China

BACKGROUND Vitamin K1(phytomenadione)is a fat-soluble naturally occurring vitamin that is widely used to treat certain coagulation *** cutaneous reactions to vitamin K1 can occur;however,owing to its low incidence and considerable variability in presentation and morphology,its diagnosis can be easily *** these reactions may be challenging for patients and ***,reviewing the adverse cutaneous reactions to vitamin K1 is *** SUMMARY Here we report the case of a 50-year-old woman with no pre-existing hepatic disease who developed a cutaneous allergic reaction to subcutaneous vitamin K1 that presented as localized eczematous plaques at the vitamin K1 injection *** eruption developed within 5 d of the injection and persisted for 32 mo despite treatment with topical and intralesional *** was diagnosed based on the results of the pathological examination,immunohistochemical staining,and a skin *** patient was advised to take herbal medicines orally twice *** treatment and follow-up,the patient’s eczematous urticarial plaques improved and her condition *** Here we present the first case of a cutaneous allergic reaction to subcutaneous vitamin K1 that was successfully treated with Chinese medicine.

关键词： Vitamin K1 Subcutaneous injection Adverse reactions Herbal medicine Polyoxyethylated castor oil Case report guidelines Case report

Early esophageal carcinomas in achalasia patient after endoscopic submucosal dissection combined with peroral endoscopic myotomy:A case report

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World Journal of Clinical Cases 2023年第22期11卷 5407-5411页

作者： Bai-Quan An chun-xiao wang Hai-Yan Zhang Jin-Dong Fu Department of Gastroenterology People’s Hospital of RizhaoRizhao 276800Shandong ProvinceChina Department of Hematology People’s Hospital of RizhaoRizhao 276800Shandong ProvinceChina

BACKGROUND Achalasia is associated with high risk of esophageal ***,the optimal endoscopic surgery for patients with early esophageal carcinoma concomitant with achalasia remains *** SUMMARY A combination of concurrent endoscopic submucosal dissection(ESD)and modified peroral endoscopic myotomy(POEM)was performed on a 62-year-old male,who presented with multiple early esophageal carcinomas concomitant with *** patient exhibited an improvement in feeding obstruction,and presented no evidence of disease during the 3-year *** The combination of ESD and POEM is a feasible treatment modality for patients with early esophageal carcinoma concomitant with achalasia.

关键词： Achalasia Early esophageal carcinoma Endoscopic submucosal dissection Modified peroral endoscopic myotomy Case report

Theoretical and experimental investigations on single-atom catalysis:Pt1/FeOx for water-gas shift reaction Shan-Fei wang1,§,Yangyang Li2,3,§,Haiyan wang1,Jin-Xia Liang1(✉),chun Zhu1

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Nano Research 2024年第9期17卷 8627-8637页

作者： Shan-Fei wang Yangyang Li Haiyan wang Jin-Xia Liang chun Zhu Botao Qiao School of Chemistry and Chemical Engineering Guizhou UniversityGuiyang 550025China CAS Key Laboratory of Science and Technology on Applied Catalysis Dalian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023China University of Chinese Academy of Sciences Beijing 100049China

Oxide-supported metal single-atom catalysts(SACs)have exhibited excellent catalytic performance for water-gas shift(WGS)***,we report the single-atom catalyst Pt1/FeOx exhibits excellent medium temperature catalytic performance for WGS reactions by the density functional theory(DFT)calculations and experimental *** calculations indicate that H_(2)O molecules are easily dissociated at oxygen vacancies,and the formed*OH and*O are adsorbed on Pt1 single atoms and the adjacent O atoms,*** studying four possible reaction mechanisms,it is found that the optimal WGS reaction pathway is proceeded along the carboxyl mechanism(pathway III),in which the formation of*COOH intermediates can promote the stability of Pt1/FeOx SAC and the easier occurrence of WGS *** energy barrier of the rate-determining step during the entire reaction cycle is only 1.16 eV,showing the high activity for the medium temperature WGS reaction on Pt1/FeOx SAC,which was verified by experimental ***,the calculated turnover frequencies(TOFs)of CO_(2)and H_(2)formation on Pt1/FeOx at 610 K(337℃)can reach up to 1.14×10^(-3)s^(-1)·site^(-1)through carboxyl *** this work,we further expand the application potential of Pt1/FeOx SAC in WGS reaction.

关键词： water-gas shift(WGS)reaction single-atom catalyst(SAC) density functional theory(DFT) thermocatalysis

Current status and prospects of research on 1,4-dioxane pollution and treatment technologies in the water environment

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Journal of Groundwater Science and Engineering 2023年第2期11卷 158-170页

作者： chun-xiao wang Yong Qian Zhao-ji Zhang Chen Yue chun-yan Guo Xiang-xiang Cui Institute of Hydrogeology and Environmental Geology Chinese Academy of Geological SciencesShijiazhuang 050061China Key Laboratory of Groundwater Contamination and Remediation China Geological Survey(CGS)&Hebei ProvinceShijiazhuang 050061China

1,4-dioxane pollution is characterized by its early identification, widespread sources and extensive distribution. The pollutant is highly mobile and persistent in the water environment and is classified as a B2(probable) human carcinogen. After reviewing recent researches on the pollution status,transport and transformation characteristics of 1,4-dioxane in the water environment, as well as the environmental pollution remediation and treatment technologies, and the status of environmental regulation,this paper addresses that the distribution of 1,4-dioxane in water bodies is significantly correlated with chlorinated hydrocarbon pollutants such as 1,1,1-trichloroethane(1,1,1-TCA) and trichloroethylene(TCE).It is noteworthy that 1,4-dioxane often occurs in symbiosis with 1,1,1-TCA and has a similarity contamination plume distribution to 1,1,1-TCA. The natural attenuation of 1,4-dioxane in groundwater environment is weak, but there is a certain degree of biological oxidation attenuation. Current methods for treating 1,4-dioxane pollution mainly include extraction-treatment technology, advanced oxidation treatment technology, modified biological treatment technology and phytoremediation technology, all of which have their limitations in practical application. Currently, there is no environmental regulation available for the 1,4-dioxane pollution worldwide, and no enforceable standard established for defining the health trigger levels of 1,4-dioxane in drinking water. Research on this contaminant in China is generally limited to the site or laboratory scale, and there are no studies on the environmental risk and quality standards for 1,4-dioxane in the water environment.

关键词： 1 4-dioxane Chlorinated hydrocarbon Environmental pollution Attenuation

MdbHLH162 connects the gibberellin and jasmonic acid signals to regulate anthocyanin biosynthesis in apple

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Journal of Integrative Plant Biology 2024年第2期66卷 265-284页

作者： Jian-Ping An Rui-Rui Xu xiao-Na wang xiao-Wei Zhang chun-Xiang You Yuepeng Han Apple technology innovation center of Shandong Province College of Horticulture Science and EngineeringShandong Agricultural UniversityTai-An 271018China CAS Key Laboratory of Plant Germplasm Enhancement and Specialty Agriculture Wuhan Botanical GardenHubei Hongshan LaboratoryThe Innovative Academy of Seed Design of Chinese Academy of SciencesWuhan 430074China College of Biology and Oceanography Weifang UniversityWeifang 261061China

Anthocyanins are secondary metabolites induced by environmental stimuli and developmental *** positive regulators of anthocyanin biosynthesis have been reported,whereas the anthocyanin repressors have been *** the signal transduction pathways of gibberellin(GA)and jasmonic acid(JA)and their regulation of anthocyanin biosynthesis have been investigated,the cross-talk between GA and JA and the antagonistic mechanism of regulating anthocyanin biosynthesis remain to be *** this study,we identified the anthocyanin repressor MdbHLH162 in apple and revealed its molecular mechanism of regulating anthocyanin biosynthesis by integrating the GA and JA ***162 exerted passive repression by interacting with MdbHLH3 and MdbHLH33,which are two recognized positive regulators of anthocyanin ***162 negatively regulated anthocyanin biosynthesis by disrupting the formation of the anthocyanin-activated MdMYB1-MdbHLH3/33complexes and weakening transcriptional activation of the anthocyanin biosynthetic genes MdDFR and MdUF3GT by MdbHLH3 and *** GA repressor MdRGL2a antagonized MdbHLH162-mediated inhibition of anthocyanins by sequestering MdbHLH162 from the MdbHLH162-MdbHLH3/33 *** JA repressors MdJAZ1 and MdJAZ2 interfered with the antagonistic regulation of MdbHLH162 by MdRGL2a by titrating the formation of the MdRGL2a-MdbHLH162 *** findings reveal that MdbHLH162 integrates the GA and JA signals to negatively regulate anthocyanin *** study provides new information for discovering more anthocyanin biosynthesis repressors and explores the cross-talk between hormone signals.

关键词： anthocyanin biosynthesis bHLH transcription factor gibberellin jasmonic acid regulatory network transcriptional regulation

Vortex identification based on the Liutex method and its effect on fish passage upstream

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Journal of Hydrodynamics 2024年第1期36卷 130-141页

作者： chun-ying Shen Rui-guo Yang xiao-tao Shi Ming-ming wang Shi-hua He Faculty of Electrical Power Engineering Kunming University of Science and TechnologyKunming650500China Hubei International Science and Technology Cooperation Base of Fish Passage China Three Gorges UniversityYichang443002China Shanghai Investigation Design and Research Institute Co.LtShanghai200434China

Fishway research is important for mitigating the fragmentation of river habitats caused by hydraulic *** vertical slit fishway is a broadly used fishway type because of its high efficiency and adaptability to water ***,the resulting vortex current disrupts the fish passage hence directly affecting fish *** study aims to accurately capture the vortex structure in the fishway and analyze the effect of vortex elements(vortex structure,vortex intensity,etc.)on *** conducted an analysis of the 3-D current flow field in the fishway through the utilization of an experimental model and the large eddy simulation(LES)***,we captured the vortex information in the fishway at different flow rates using the Liutex vortex identification method and investigated the effect of the vortex on fish *** results revealed that the structures inside the fishway pool occupy most of the room,however,the areas with higher vortex strength were primarily located in the vortex near the vertical seam and the mainstream,the vortex strength inside the fishway gradually increases with increasing flow,suppressing fish *** experienced significantly increased resistance when encountering strong *** suggests that the vortex may act as a physical barrier to fish *** findings highlight the potential negative effects of vortex on fish movement and reiterate the importance of understanding vortex dynamics for aquatic environmental *** an effective tool for identifying vortices in fluid flow,the Liutex method demonstrates features of vortex within the fishway,thereby providing important insights into the interaction between fluid dynamics and aquatic organisms.

关键词： Vertical slit fishway vortex identification method Liutex large eddy simulation(LES) fish experiment computational fluid dynamics

Three-dimensional Modeling of Ore-forming Elements and Mineralization Prognosis for the Yechangping Mo Deposit,Henan Province,China

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Acta Geologica Sinica(English Edition) 2024年第3期98卷 736-752页

作者： DING Gaoming JI Genyuan YAN Guolong XU Yongzhong wang Kunming xiao chun wang Quanle GUO Dongbao China National Administration of Coal Geology Beijing 100038China MNR Key Laboratory of Metallogeny and Mineral Assessment Institute of Mineral ResourcesCAGSBeijing 100037China China Gold Group Geological Co. Ltd.Beijing 100011China China Gold Group ZhongYuan Mining Co. Ltd.SanmenxiaHenan 472000China Lanzhou Mineral Exploration Institute of Gansu Nonferrous Metal Geological Exploration Bureau Lanzhou 730046China

Three-dimensional geochemical modeling of ore-forming elements is crucial for predicting deep *** approach provides key information for the quantitative prediction of deep mineral localization,three-dimensional fine interpolation,analysis of spatial distribution patterns,and extraction of quantitative mineral-seeking *** Yechangping molybdenum(Mo)deposit is a significant and extensive porphyry-skarn deposit in the East Qinling-Dabie Mo polymetallic metallogenic belt at the southern margin of the North China *** borehole data on oreforming elements underpin deep geochemical *** methodology includes the following steps:(1)Threedimensional geological modeling of the deposit was established.(2)Correlation,cluster,and factor analyses post delineation of mineralization stages and determination of mineral generation sequence to identify(Cu,Pb,Zn,Ag)and(Mo,W,mfe)assemblages.(3)A three-dimensional geochemical block model was constructed for Mo,W,mfe,Cu,Zn,Pb,and Ag using the ordinary kriging method,and the variational function was developed.(4)Spatial distribution and enrichment characteristics analysis of ore-forming elements are performed to extract geological information,employing the variogram and w(Cu+Pb+Zn+Ag)/w(Mo+W)as predictive indicators.(5)Identifying the western,northwestern,and southwestern areas of the mine with limited mineralization potential,contrasted by the northeastern and southeastern areas favorable for mineral exploration.

关键词： 3D geochemical model ore-forming elements geostatistics deep mineralization prediction Yechangping Mo deposit

Efficient hierarchical identity based encryption scheme in the standard model over lattices

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Frontiers of Information Technology & Electronic Engineering 2016年第8期17卷 781-791页

作者： Feng-he wang chun-xiao wang Zhen-hua LIU Department of Mathematics and Physics Shandong Jianzhu University Jinan 250014 China School of Mathematics and Statistics Xidian University Xi'an 710071 China

本文在标准模型下,利用固定维数的格基代理算法提出了一种高效的格基分级身份加密方案。其公钥尺寸仅为(dm2+mn)log q比特,而消息-密文扩展因子仅为log q,其中d为最大分级深度,(n,m,q)为公开参数。本文构造了一种新的公钥赋值算法,将1... 详细信息

本文在标准模型下,利用固定维数的格基代理算法提出了一种高效的格基分级身份加密方案。其公钥尺寸仅为(dm2+mn)log q比特,而消息-密文扩展因子仅为log q,其中d为最大分级深度,(n,m,q)为公开参数。本文构造了一种新的公钥赋值算法,将1个随机、公开的矩阵平均赋值为两个身份比特,从而仅仅需要d个公开矩阵来构造标准模型下的HIBE方案;与之相比,Crypto 2010所提出的HIBE方案中需要2d个同样尺寸的矩阵,公钥尺寸达到(2dm2+mn+m)log q。为了将该方案的消息-密文扩展因子压缩到log q,本文基于Gentry的加密方案建立了一种基础加密算法,一次加密操作中能够加密m2比特明文并得到m2log q比特密文。因此,文中所提方案在公钥尺寸、消息-密文扩展因子等方面具有一定的优势。基于差错学习问题的困难性,我们证明该方案在选择身份、选择明文攻击下是安全的。

关键词：加密方案标准模型分层基公共密钥扩展因子选择明文攻击分配规则矩阵和