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Endoscopic sphincterotomy plus large-balloon dilation vs endoscopic sphincterotomy for choledocholithiasis:A meta-analysis

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World Journal of Gastroenterology 2013年第48期19卷 9453-9460页

作者： xiao-ming yang Bing Hu Department of Endoscopy Eastern Hepatobiliary Surgery Hospital Second Military Medical University

AIM:To perform a meta-analysis of large-balloon dilation(LBD)plus endoscopic sphincterotomy(EST)vs EST alone for removal of bile duct ***:Databases including PubMed,EMBASE,the Cochrane Library,the Science Citation Index,and important meeting abstracts were searched and evaluated by two reviewers *** main outcome measures included:complete stone removal,stone removal in the first session,use of mechanical lithotripsy,procedure time,and procedure-related complications.A fixed-effects model weighted by the Mantel-Haenszel method was used for pooling the odds ratio(OR)when heterogeneity was not significant among the *** a Q test or I2statistic indicated substantial heterogeneity,a random-effects model weighted by the DerSimonian-Laird method was ***:Six randomized controlled trials involving835 patients were *** was no significant heterogeneity for most results;we analyzed these using a fixed-effects ***-analysis showed EST plus LBD caused fewer overall complications than EST alone(OR=0.53,95%CI:0.33-0.85,P=0.008);sub-category analysis indicated a significantly lower risk of perforation in the EST plus LBD group(Peto OR=0.14,95%CI:0.20-0.98,P=0.05).Use of mechanical lithotripsy in the EST plus LBD group decreased significantly(OR=0.26,95%CI:0.08-0.82,P=0.02),especially in patients with a stone size larger than 15 mm(OR=0.15,95%CI:0.03-0.68,P=0.01).There were no significant differences between the two groups regarding complete stone removal,stone removal in the first session,post-endoscopic retrograde cholangiopancreatography pancreatitis,bleeding,infection of biliary tract,and procedure ***:EST plus LBD is an effective approach for the removal of large bile duct stones,causing fewer complications than EST alone.

关键词： Balloon dilation Cholangiopancreatography Endoscopic retrograde Choledocholithiasis Endoscopic sphincterotomy Meta-analysis

Synthesis of Cyclic Oligo(ethylene adipate)s and Their Melt Polymerization to Poly(ethylene adipate)

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Chinese Journal of Polymer Science 2017年第9期35卷 1051-1060页

作者： min lu xiang zhu xiao-hong li xiao-ming yang 屠迎锋 Jiangsu Key Laboratory of Advanced Functional Polymer Design and Application State and Local Joint Engineering Laboratory for Novel Functional Polymeric Materials College of Chemistry Chemical Engineering and Materials Science Soochow University Suzhou 215123 China

We present here the first synthesis of cyclic oligo（ethylene adipate）s （COEAs） via pseudo-high dilution condensation reaction of adipoyl chloride with ethylene glycol, and the synthesis of corresponding poly（ethylene adipate）（PEA） via the melt polymerization of COEAs. The structure of COEAs was characterized and proved by 1H-NMR and MALDI-TOF mass measurements. The effects of organic base, reaction temperature and the ratio of adipoyl chloride to ethylene glycol on the yield of COEAs were studied, and the optimum reaction condition was revealed. PEA, a diacid and diol based semi-crystalline green aliphatic polyester, was synthesized by the melt polymerization of COEAs using Ti（n-C4H90）4 as catalyst and 1,10-decanediol as initiator at 200 ℃, which follows the polycondensation-coupling ring- opening polymerization method. Our strategy should be applicable to the synthesis of versatile aliphatic polyesters based on diacid and diol monomers, which have potential applications as biocompatible and biodegradable materials.

关键词： Cyclic oligoesters Pseudo-high dilution reaction condition Polycondensation-coupling ring-openingpolymerization Aliphatic polyesters

Thermodynamics of Aromatic Cyclic Ester Polymerization in Bulk

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Chinese Journal of Polymer Science 2019年第1期37卷 89-93页

作者： Chong He Xiang Zhu xiao-Hong Li xiao-ming yang Ying-Feng Tu Jiangsu Key Laboratory of Advanced Functional Polymer Design and Application College of Chemistry Chemical Engineering and Materials ScienceSoochow University

We present here the thermodynamic investigation of in situ cascade polycondensation-coupling ring-opening polymerization(PROP)for three cyclic aromatic ester monomers,i.e.,cyclic oligo(2-methyl-1,3-propylene terephthalate)s(COMPTs),cyclic oligo(neopentylene terephthalate)s(CONTs)and cyclic oligo(2-methyl-2-propyl-1,3-propylene terephthalate)s(COMPPTs).The equibrium monomer to polymer weight ratio in bulk at different polymerization temperatures for each monomer was estimated by the size exclusion chromatography(SEC),and the thermodynamic parameters were estimated by Dainton *** different from the thermodynamics of aliphatic lactones polymerization,which is an exothermic process with entropy reduction,our results showed the polymerization thermodynamics for three cyclic aromatic ester monomers was a weak exothermic process with slight entropy increment,i.e.,a both enthalpy and entropy driving *** them,CONTs showed the largest value of enthalpy change,due to its symmetric dimethyl substitution onβ-position of propandiol segments.

关键词： Lactone Polyester Polycondensation-coupling ring-opening polymerization Thermodynamic parameters

Pricing in combinatorial double auction-based grid allocation model

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The Journal of China Universities of Posts and Telecommunications 2009年第3期16卷 59-65页

作者： LI Li LIU Yuan-an LIU Kai-ming MA xiao-lei yang ming Key Laboratory of Universal Wireless Communications Ministry of Education Beijing University of Posts and Telecommunications Beijing 100876 China

This article proposes a novel grid resource allocation model, in which the users and the grid service providers participate in the combinatorial double auction for the resource allocation. To obtain the detailed resource allocation status and the price information, a novel pricing algorithm is designed for the allocation model. Simulation results demonstrate that the proposed algorithm completes the resource allocation and pricing efficiently, and exhibits incentive compatible characteristic. Moreover, users with the higher average price and providers with the lower average price get compensation during the pricing process.

关键词： grid combinatorial double auction resource allocation pricing

Non-line-of-sight error mitigating algorithm based on scattering models via multi-antenna system

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The Journal of China Universities of Posts and Telecommunications 2008年第1期15卷 18-22页

作者： ZHU xiao-xuan SHI ming-yang ZHANG Jing TAO xiao-feng Key Laboratory of Universal Wireless Communications Beijing University of Posts and Telecommunications Ministry of Education Wireless Technology Innovation Institute (WTI) Beijing 100876 China

In urban environment with serious blocking of direct paths, the non-line-of-sight （NLOS） propagation influences the location estimation accuracy. In this article, a novel algorithm is developed, which can mitigate the NLOS errors in location estimation significantly. Utilizing multiantenna array, the information of scatterers that cause the NLOS propagation is obtained. Then, we combine the information with TOA/TDOA based location algorithm to estimate the location of mobile station （MS）. The simulation results show that our method can mitigate NLOS errors and enhance the location accuracy greatly.

关键词： multi-antenna location algorithm NLOS time of arrival (TOA)

Hydrogen peroxide biosensor based on electrodeposition of zinc oxide nanoflowers onto carbon nanotubes film electrode

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Chinese Chemical Letters 2008年第3期19卷 314-318页

作者： Hui Ping Bai Xu xiao Lu Guang ming yang Yun Hui yang Department of Chemistry and Chemical Engineering Yunnan Normal University Kunming 650092 China

A new amperometric biosensor for hydrogen peroxide was developed based on adsorption of horseradish peroxidase at the glassy carbon electrode modified with zinc oxide nanoflowers produced by electrodeposition onto multi-walled carbon nanotubes （MWNTs） film. The morphology of the MWNTs/nano-ZnO electrode has been investigated by scanning electron microscopy （SEM）, and the electrochemical performance of the electrode has also been studied by amperometric method. The resulting electrode offered an excellent detection for hydrogen peroxide at -0.11 V with a linear response range of 9.9×10^-7 to 2.9×10^-3 mol/L with a correlation coefficient of 0.991, and response time 〈5 s. The biosensor displays rapid response and expanded linear response range, and excellent stability.

关键词： Multi-walled carbon nanotubes Biosensor Electrodeposition Horseradish peroxidase ZnO nanoflowers

Physiological Responses of Limonium aureum Seeds to Ultra-drying

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Journal of Integrative Plant Biology 2007年第5期49卷 569-575页

作者： Yi Li Hu-Yuan Feng Tuo Chen xiao-ming yang Li-Zhe An School of Life Sciences Lanzhou University Lanzhou 730000 China Cold and Arid Region Environmental and Engineering Research Institute Chinese Academy of Sciences Lanzhou 730000 China

The seeds of Limonium aureum （L.） Hill. were dried from 8.92% to 2.88% moisture content in a desiccating container with silica gel. After ultra-drying the seeds were accelerated aged （50 ℃, 1 month）, and some physiological indices, including the electrical conductivity, dehydrogenase activity, superoxide dismutase （SOD）, peroxidase （POD）, glutathione reductase （GR）, ascorbate peroxidase （APX）, catalase （CAT）, volatile aldehydes and malondialdehyde （MDA） were tested. The results indicated that dehydrogenase, POD, SOD, GR, APX and CAT activities of the ultra-dry seeds were higher than the control seeds, while volatile aldehydes and malondialdehyde were lower than the control group. The results suggest that ultra-drying is beneficial for maintaining the vigor of L. aureum seeds at a high level. Thus, L. aureum seeds could be stored under ultra-dry conditions.

关键词： electrical conductivity Limonium aureum seed physiological indices ultra-dry.

Special Odd-Even Effect of Degree of Oligomerization on Properties of Cyclic Oligoesters

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Chinese Journal of Polymer Science 2015年第8期33卷 1069-1069,1070-1073页

作者： Jun Wu Tao-guang Qu Ling-feng Gao xiao-ming yang xiao-hong Li 屠迎锋 Xiu-lin Zhu Suzhou Key Laboratory of Macromolecular Design and Precision Synthesis Jiangsu Key Laboratory of Advanced Functional Polymer Design and ApplicationCollege of ChemistryChemical Engineering and Materials ScienceSoochow University

We demonstrate here seven pure cyclic samples, which belongs to two series of oligoesters, cyclic oligo（trimethylene terephthalate）s （COTTs） and cyclic oligo（butylene terephthalate）s （COBTs）, showing odd-even effect of degree of oligomerization （repeating units number） on properties. The pentamer of COTT and trimer of COBT show much lower melting temperature, and the trimer of COTT and trimer of COBT show significant lower refractive index, which can be ascribed to the low packing density of cyclic oligoesters with odd number of degree of oligomerization. Our results reveal the discrete property change as a function of cyclic size of oligomers, which can be used to design materials with special properties.

关键词： Cyclic polymer Oligomer Odd-even effect Refractive index.

Toll-like receptor 5-mediated signaling enhances liver regeneration in mice

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Military Medical Research 2021年第4期8卷 490-502页

作者： Wen Zhang Lei Wang Xue-Hua Sun Xian Liu yang xiao Jie Zhang Ting Wang Hui Chen Yi-Qun Zhan Miao Yu Chang-Hui Ge Chang-Yan Li Guang-ming Ren Rong-Hua Yin xiao-ming yang Department of Pharmaceutical Engineering School of Chemical Engineering and TechnologyTianjin UniversityTianjin 300072China. State Key Laboratory of Proteomics Beijing Proteome Research CenterNational Center for Protein Sciences(Beijing)Beijing Institute of LifeomicsBeijing 102206China. School of Basic Medical Sciences Anhui Medical UniversityHefei 230032Anhui ProvinceChina. Beijing Institute of Radiation Medicine Beijing 100850China.

Background:Toll-like receptor 5(TLR5)-mediated pathways play critical roles in regulating the hepatic immune response and show hepatoprotective effects in mouse models of hepatic ***,the role of TLR5 in experimental models of liver regeneration has not been *** study aimed to investigate the role of TLR5 in partial hepatectomy(PHx)-induced liver ***:We performed 2/3 PHx in wild-type(WT)mice,TLR5 knockout mice,or TLR5 agonist CBLB502 treated mice,as a model of liver *** flagellin content was measured with ELISA,and hepatic TLR5 expression was determined with quantitative PCR analyses and flow *** study the effects of TLR5 on hepatocyte proliferation,we analyzed bromodeoxyuridine(BrdU)incorporation and proliferating cell nuclear antigen(PCNA)expression with immunohistochemistry(IHC)*** effects of TLR5 during the priming phase of liver regeneration were examined with quantitative PCR analyses of immediate early gene mRNA levels,and with Western blotting analysis of hepatic NF-κB and STAT3 *** and growth factor production after PHx were detected with real-time PCR and cytometric bead array(CBA)*** Red O staining and hepatic lipid concentrations were analyzed to examine the effect of TLR5 on hepatic lipid accumulation after ***:The bacterial flagellin content in the serum and liver increased,and the hepatic TLR5 expression was significantly up-regulated in WT mice after ***5-deficient mice exhibited diminished numbers of BrdU-and PCNA-positive cells,suppressed immediate early gene expression,and decreased cytokine and growth factor ***,PHx-induced hepatic NF-κB and STAT3 activation was inhibited in Tlr5–/–mice,as compared with WT ***,the administration of CBLB502 significantly promoted PHx-mediated hepatocyte proliferation,which was correlated with enhanced production of proinflammatory cytokines and the recruitment of macrophages

关键词： Liver regeneration Partial hepatectomy Toll-like receptor 5 CBLB502 NF-κB