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Progress in the development of the 122-type IBS wires

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Superconductivity 2022年第2期2卷 17-22页

作者： xianping zhang Yanwei Ma Key Laboratory of Applied Superconductivity Institute of Electrical EngineeringChinese Academy of SciencesBeijing 100190People’s Republic of China University of Chinese Academy of Sciences Beijing 100049People’s Republic of China Institute of Electrical Engineering and Advanced Electromagnetic Drive Technology Qilu ZhongkeJinan 250013People’s Republic of China

Profit from their low anisotropy and high upper critical field,iron-based superconductors(IBSs)have great potential for high magnetic fields *** progress has been made for the current density improvement of(Sr,Ba)0.6K0.4Fe2As2(122-type)IBS wires over the past fourteen *** this article,an overview of the preparation procedures and key issues affecting the critical current performance of 122-type IBS wires is given,to provide a fundamental understanding of what controls the transport critical current density of 122-type IBS ***,the recent developments for 122-type IBS wires are presented and future prospect and challenges in the development of 122-type IBS wires for practical applications are discussed.

关键词： Iron-based superconductor 122-type Wire Technique

二甲双胍对糖尿病大鼠全层皮肤缺损创面愈合的作用及其机制

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中华烧伤与创面修复杂志 2024年第6期40卷 579-588页

作者：王宝宏张艳冰张先平李玉婷伍智慧扈容英赵诗乐蒋宏娜姚雨薇董俭达宁夏医科大学基础医学院银川750004 西安市胸科医院病理科西安710100 宁夏医科大学总医院皮肤科银川750004 宁夏医科大学临床医学院银川750004

目的探讨二甲双胍对糖尿病大鼠全层皮肤缺损创面愈合的作用及其机制。方法该研究为实验研究。将18只8周龄雄性SD大鼠按照完全随机分组法分为对照组、糖尿病组及糖尿病+二甲双胍组,每组6只。将后2组大鼠制成糖尿病模型,然后在18只大鼠背... 详细信息

目的探讨二甲双胍对糖尿病大鼠全层皮肤缺损创面愈合的作用及其机制。方法该研究为实验研究。将18只8周龄雄性SD大鼠按照完全随机分组法分为对照组、糖尿病组及糖尿病+二甲双胍组,每组6只。将后2组大鼠制成糖尿病模型,然后在18只大鼠背部各制备4个直径5 mm的圆形全层皮肤缺损创面。仅在糖尿病+二甲双胍组大鼠创面涂抹二甲双胍F-127水凝胶。观察伤后7、13 d创面愈合情况并计算创面愈合率。收集伤后7、13 d创面组织,行苏木精-伊红染色,检测再上皮化表皮长度,计算表皮和真皮创面直径变化率;行免疫组织化学染色后,检测角蛋白10和增殖细胞核抗原(PCNA)的相对表达;行蛋白质印迹法检测角蛋白10和PCNA的蛋白表达。最后1个实验样本数为3,其余实验样本数均为8。分析3组大鼠创面组织中角蛋白10、PCNA相对表达与创面愈合率间的相关性,创面组织中角蛋白10相对表达和PCNA相对表达间的相关性。结果伤后7 d,糖尿病组与糖尿病+二甲双胍组大鼠创面愈合率分别为81.48%(77.89%,85.53%)、93.04%(92.51%,94.24%),均明显低于对照组的100%(97.17%,100%),Z值分别为2.37、-3.36,P0.05)。对照组、糖尿病+二甲双胍组大鼠伤后13 d创面再上皮化表皮长度均明显长于糖尿病组(Z值分别为3.34、-2.64,P<0.05)。糖尿病组大鼠伤后7、13 d创面组织中角蛋白10的相对表达均明显高于对照组(Z值分别为-3.36、-3.26,P<0.05)和糖尿病+二甲双胍组(Z值分别为3.36、3.15,P<0.05),糖尿病+二甲双胍组大鼠伤后7 d创面组织中角蛋白10相对表达明显低于对照组(Z=3.05,P<0.05);糖尿病组大鼠伤后7、13 d创面组织中PCNA相对表达均明显低于对照组(Z值均为3.36,P<0.05)和糖尿病+二甲双胍组(Z值均为-3.36,P<0.05)。对照组和糖尿病+二甲双胍组大鼠伤后7 d创面组织中角蛋白10蛋白表达及糖尿病+二甲双胍组大鼠伤后13 d创面组织中角蛋白10蛋白表达均明显低于糖尿病组(P<0.05),对照组和糖尿病+二甲双胍组大鼠伤后7 d创面组织中PCNA蛋白表达均明显高于糖尿病组(P<0.05)。对照组和糖尿病+二甲双胍组大鼠创面组织中角蛋白10相对表达和创面愈合率均呈显著正相关(r值分别为0.78、0.71,P<0.05),糖尿病+二甲双胍组大鼠创面组织中PCNA相对表达和创面愈合率呈显著负相关(r=-0.60,P<0.05),糖尿病组和糖尿病+二甲双胍组大鼠创面组织中PCNA相对表达与角蛋白10相对表达均呈显著负相关(r值分别为-0.41、-0.49,P<0.05)。结论糖尿病大鼠全层皮肤缺损创面延迟愈合并伴有创面组织KC中的角蛋白10上调及PCNA下调。二甲双胍通过下调创面组织KC中的角蛋白10表达和上调PCNA表达,促进糖尿病大鼠全层皮肤缺损创面愈合,且创面愈合率与角蛋白10的表达呈正相关,与PCNA的表达呈负相关。

关键词：二甲双胍糖尿病细胞增殖细胞分化角质形成细胞创面修复

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春化蚕豆处理时间及种植密度试验

浙江农业科学 2024年第3期65卷 571-573页

作者：王琴霞张仙平朱伟君江立斌王宏辉温岭市农业技术推广总站浙江温岭317500

为提前和延长蚕豆采摘期,增加鲜食蚕豆种植效益,开展蚕豆春化处理时间及种植密度试验。结果表明,蚕豆4℃下春化达20~30 d,可以显著提早蚕豆采摘期,拉长采摘周期,显著提高每株豆荚数和百荚重,从而提高鲜荚单位面积产量。春化处理30 d,可... 详细信息

为提前和延长蚕豆采摘期,增加鲜食蚕豆种植效益,开展蚕豆春化处理时间及种植密度试验。结果表明,蚕豆4℃下春化达20~30 d,可以显著提早蚕豆采摘期,拉长采摘周期,显著提高每株豆荚数和百荚重,从而提高鲜荚单位面积产量。春化处理30 d,可显著增加每荚粒数、荚长,降低始花节位。降低种植密度可以增加单株豆荚数、单株分枝数,未对单位面积产量造成显著影响。667 m^(2)种植1500株(株距35 cm)是最佳的选择,在不减产的情况下,可以节省用种量,降低生产成本和用工,同时又能提高鲜食蚕豆品质。本次试验可为温岭市蚕豆生产提供技术支撑。

关键词：蚕豆春化密度

Calcium-fortified fresh milk ameliorates postmenopausal osteoporosis via regulation of bone metabolism and gut microbiota in ovariectomized rats

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Food Science and Human Wellness 2024年第3期13卷 1258-1270页

作者： Qishan Wang Bin Liu xianping Li Junying Zhao Zongshen zhang Weicang Qiao Xinyue Wei Lijun Chen School of Bioengineering Dalian Polytechnic UniversityDalian 116034China National Engineering Research Center of Dairy Health for Maternal and Child Beijing Sanyuan Foods Co.Ltd.Beijing 100163China Beijing Engineering Research Center of Dairy Beijing Sanyuan Foods Co.Ltd.Beijing 100163China

The aging of the global population has made postmenopausal osteoporosis prevention essential;however,pharmacological treatments are ***,we evaluate the effect of calcium-fortified fresh milk(FM)in ameliorating postmenopausal osteoporosis in a rat model established using bilateral *** 3 months of FM(containing vitamin D,and casein phosphopeptides,1000 mg Ca/100 g)or control milk(110 mg Ca/100 g milk)supplementation,bone changes were assessed using dual-energy X-ray absorptiometry,microcomputed tomography,and bone biomechanical *** results revealed that FM can regulate bone metabolism and gut microbiota composition,which act on bone metabolism through pathways associated with steroid hormone biosynthesis,relaxin signaling,serotonergic synapse,and unsaturated fatty acid ***,FM administration significantly increased bone mineral content and density in the lumbar spine and femur,as well as femoral compressive strength,while improving femoral trabecular bone parameters and ***,we found that the effects may be due to increased levels of estrogen,bone formation marker osteocalcin,and procollagen typeⅠN-propeptide,and decreased expression of the bone resorption marker C-telopiptide and tartrate-resistant acid phosphatase ***,the findings suggest that FM is a potential alternative therapeutic option for ameliorating postmenopausal osteoporosis.

关键词： Dairy products Calcium Vitamin D Bone turnover markers Gut microbiota Postmenopausal osteoporosis

Heat treatment effects on the superconducting properties of Ag-doped SrKFeAs compounds

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Science China(Physics,Mechanics & Astronomy) 2010年第7期53卷 1187-1193页

作者： zhang ZhiYu WANG Lei QI YanPeng GAO ZhaoShun WANG DongLiang zhang xianping MA YanWei Key Laboratory of Applied Superconductivity Institute of Electrical EngineeringChinese Academy of SciencesBeijing 100190China

The superconducting properties of polycrystalline Sr0.6K0.4Fe2As2 were strongly influenced by Ag doping(***.23(2010) 025027).Ag addition is mainly dominated by silver diffusing,so the annealing process is one of the essential factors to achieve high quality Ag doped *** this paper,the optimal annealing conditions were studied for Ag doped Sr0.6K0.4Fe2As2 bulks prepared by a one-step solid reaction *** is found that the annealing temperature has a strong influence on the superconducting properties,especially on the critical current density *** a result,higher heat treatment temperature(~900℃) is helpful in diffusing Ag and reducing the impurity phase gathered together to improve the grain *** contrast,low-temperature sintering is counterproductive for Ag doped *** results clearly suggest that annealing at ~900℃ is necessary for obtaining high Jc Ag-doped samples.

关键词： Ag doped Sr0.6K0.4Fe2As2 iron-based superconductor heat treatment

Fabrication of the 19-filament Fe/Cu clad MgB_2 wire via in situ powder-in-tube method

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Chinese Science Bulletin 2007年第19期52卷 2621-2625页

作者： YU ZhengGuang MA YanWei WANG DongLiang GAO ZhaoShun zhang xianping Applied Superconductivity Laboratory Institute of Electrical Engineering Chinese Academy of Sciences Beijing 100080 China

Using commercial amorphous B powder (92% in purity) and Mg powder (99% in purity) as starting materials, 19-filament Fe/Cu clad MgB2 wires were fabricated by an in situ powder-in-tube method. Heat treatment was performed at 700℃ for 1 h under an argon gas atmosphere. The influence of Mg/B ratio on the microstructure and superconducting properties of the wires was investigated. It was found that the major phases of MgB2 wires were MgB2 accompanied with relatively small amounts of MgO and Fe2B impurities. With 5% excess Mg addition, the onset TC slightly decreased. However, the transport JC at 4.2 K and 4 T reached 1.07×104 A·cm-2, increasing by a factor of 1.4 compared to the stoichiometric sample. Moreover, the Mg1.05B2 sample showed an improved field dependence of JC, suggesting that less voids and smaller grain size of the Mg1.05B2 core lead to better grain connectivity and stronger flux pinning.

关键词： MgB2金属导线铜铁复合物制造工业灯丝

Fabrication and superconducting properties of nano-SiC doped MgB_2 tapes

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Chinese Science Bulletin 2007年第18期52卷 2477-2480页

作者： zhang xianping MA YanWei GAO ZhaoShun YU ZhengGuang WANG DongLiang WATANABE K GUO JianDong Applied Superconductivity Laboratory Institute of Electrical Engineering Chinese Academy of Sciences Beijing 100080 China Institute for Materials Research Tohoku University Sendai 980-8577 Japan Department of Physics Peking University Beijing 100080 China

Nano-SiC doped MgB2 tapes were prepared by the in situ powder-in-tube method. Heat treatment was performed at 650℃ for 1 h. XRD data indicate that SiC particles had reacted with the MgB2 during sintering process. MgB2 core seemed to be denser after SiC doping, and the critical temperature was slightly depressed. The critical current density Jc of the SiC doped tapes was significantly enhanced in magnetic fields up to 14 T compared to the undoped ones. For the 5% SiC doped samples, Jc was in- creased by a factor of 32 at 4.2 K, 10 T. The enhancement of Jc-B properties in SiC doped MgB2 tapes is considered to be due to the enhancement of grain linkages and the introduction of effective flux pining centers. The substitution of B by C in MgB2 grains is thought to be the main reason for the improve- ment of the flux pinning ability in SiC doped MgB2 tapes.

关键词：硼化镁纳米碳化硅临界电流超导电性

260例女性生殖道解脲支原体、沙眼衣原体耐药情况分析

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中国病原生物学杂志 2023年第6期18卷 721-724,733页

作者：曾芍张先平娄底职业技术学院护理学院湖南娄底417000 南华大学附属娄底医院

目的了解解脲支原体(UU)、沙眼衣原体(CT)感染后患者血常规特点,并检测其药物敏感性,为临床治疗提供依据。方法分析UU、CT单一病原体感染者的临床资料;运用RT-PCR技术对UU和CT进行测定;采用倍比稀释法测定UU和CT对临床常用抗生素耐药情... 详细信息

目的了解解脲支原体(UU)、沙眼衣原体(CT)感染后患者血常规特点,并检测其药物敏感性,为临床治疗提供依据。方法分析UU、CT单一病原体感染者的临床资料;运用RT-PCR技术对UU和CT进行测定;采用倍比稀释法测定UU和CT对临床常用抗生素耐药情况;运用PCR技术对UU喹诺酮类药物耐药(决定)区进行扩增并测序。结果206例患者中,UU感染207例,年龄18~69(39.15±12.30)岁,BMI平均(23.52±1.49)kg/m^(2),18~、20~、30~、40~、50~和≥60岁患者分别为5、59、54、50、25和14例。CT感染53例,年龄18~65(38.47±12.52)岁,BMI平均(24.09±1.58)kg/m^(2),各年龄组患者分别为2、14、17、10、5和5例。UU感染者与CT感染者WBC、HB、LYM、BAS、EOS、PLT和SIgA值差异有统计学意义(均P<0.05)。药敏结果显示,UU对交沙霉素、美满霉素、四环素、罗红霉素、阿奇霉素、左氧氟沙星、环丙沙星和司帕沙星耐药率分别为1.93%、1.45%、8.21%、7.73%、8.70%、54.11%、56.52%和57.49%,CT耐药率分别为11.32%、7.55%、16.98%、30.19%、26.42%、26.42%、32.08%和9.43%。检测的20株UU中,gyrA发生8处碱基突变,其中7处为无义突变,1处错义突变为碱基C336A;13株UU中检出D112E突变,检出率65.00%。parC发生6处碱基突变,其中3处为无义突变。3处错义突变分别为碱基C248T、G370T和T372C,对应氨基酸突变为S83L(TCA→TTA)和G124C(GGT→TGC)。结论女性感染患者在20~40岁处于高发人群。UU对喹诺酮类药物耐药程度较高,可能与氨基酸突变有关。

关键词：女性生殖道解脲支原体沙眼衣原体耐药性

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1144型铁基超导材料的研究现状及展望

科学通报 2022年第8期67卷 758-769页

作者：成者张现平董持衡马衍伟中国科学院电工研究所应用超导重点实验室北京100190 南昌大学理学院南昌330031 中国科学院大学工程科学学院北京100049

以122型为代表的铁基超导体在临界电流密度、上临界场以及各向异性方面具有较大的优势,引发了新一轮研究热潮.目前,虽然122型线带材的性能已达到实用化水平,但该体系仍存超导相非均匀分布等问题,限制了其载流性能的提升.新发现的具有化... 详细信息

以122型为代表的铁基超导体在临界电流密度、上临界场以及各向异性方面具有较大的优势,引发了新一轮研究热潮.目前,虽然122型线带材的性能已达到实用化水平,但该体系仍存超导相非均匀分布等问题,限制了其载流性能的提升.新发现的具有化学计量比的1144型超导材料具有更好的均匀性、独特的钉扎特性以及更高的载流性能,使其适合于高场应用.本文简述了1144材料的结构和超导特性,并详细分析了单晶、多晶及超导线带材制备工艺的优化,以及性能提升的方法.同时,为提高1144型铁基超导线带材的临界电流密度,讨论了改善晶粒连接性和超导相纯度的途径.

关键词： 1144型铁基超导体单晶线带材辐照临界电流密度