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The model of taking electronic medical records as the core for information construction in hospitals＂

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Chinese Medical Journal 2013年第2期126卷 373-377页

作者： WU Tao XU Ke LI Ping LI xian-feng XU wei-guo Xinhua Hospital Shanghai Jiao Tong University School ofMedicine Shanghai 200092 China

The development of hospital information has been carried out for nearly 50 years, and originally started Le hospital information system （HIS）1 So far HIS isas the hospital information system （HIS）J So far HIS is the most widely and deeply used management system for hospitals in China.2 ＂General function standard for hospital information system＂ issued by China＇s Ministry of Health in 2002 defined that ＂The hospital information system refers to using of computer hardware and software technology, network communications technology, and other modem technology to comprehensively manage personnel, logistics, and finance in various departments in hospital. Gather, store, treat, extract, transport, aggregate,and process data in various stages of the medical activities, so that provide comprehensive and automatic information management and service to the hospital.＂

关键词： electronic medical record hospital information construction

Role of bone marrow-derived mesenchymal stem cells in a rat model of severe acute pancreatitis

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World Journal of Gastroenterology 2012年第18期18卷 2270-2279页

作者： Xiao-Huang Tu Jing-xiang Song Xiao-Jun Xue xian-wei guo Yun-Xia Ma Zhi-Yao Chen Zhong-Dong Zou Lie Wang Department of General Surgery Fuzhou General Hospital of Nanjing Military RegionFuzhou 350025Fujian ProvinceChina

AIM:To investigate the role and potential mechanisms of bone marrow mesenchymal stem cells(MSCs) in severe acute peritonitis(SAP).METHODS:Pancreatic acinar cells from Sprague Dawley rats were randomly divided into three groups:nonsodium deoxycholate(SDOC) group(non-SODC group),SDOC group,and a MSCs intervention group(i.e.,a co-culture system of MSCs and pancreatic acinar cells + SDOC).The cell survival rate,the concentration of malonaldehyde(MDA),the density of superoxide dismutase(SOD),serum amylase(AMS) secretion rate and lactate dehydrogenase(LDH) leakage rate were detected at various time *** a separate study,Sprague Dawley rats were randomly divided into either an SAP group or an SAP + MSCs *** AMS,MDA and SOD,interleukin(IL)-6,IL-10,and tumor necrosis factor(TNF)-α levels,intestinal mucosa injury scores and proliferating cells of small intestinal mucosa were measured at various time points after injecting either MSCs or saline into *** both studies,the protective effect of MSCs was ***:In vitro,The cell survival rate of pancreatic acinar cells and the density of SOD were significantly reduced,and the concentration of MDA,AMS secretion rate and LDH leakage rate were significantly increased in the SDOC group compared with the MSCs intervention group and the Non-SDOC group at each time *** vivo,Serum AMS,IL-6,TNF-α and MAD level in the SAP + MSCs group were lower than the SAP group;however serum IL-10 level was higher than the SAP *** SOD level was higher than the SAP group at each time point,whereas a significant betweengroup difference in SOD level was only noted after 24 *** mucosa injury scores was significantly reduced and the proliferating cells of small intestinal mucosa became obvious after injecting ***:MSCs can effectively relieve injury to pancreatic acinar cells and small intestinal epithelium,promote the proliferation of enteric epithelium and repair of the mucosa,attenuate systemic in

关键词： Bone marrow mesenchymal stem cells Severe acute pancreatitis Intestinal barricade function Pancreatic acinar cells

TNF-α up-regulates Nav1.3 in dorsal root ganglion after nerve injury

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TNF-α up-regulates Nav1.3 in dorsal root ganglion after ne...

Analysis of Micromechanical Properties at the Interface of Pre-wet SBS Modified Asphalt Mixture Based on Molecular Simulation Technology

中国神经科学学会第四次会员代表大会暨第七届全国学术会议

作者： Ying ZANG,Xu-Hong wei,xian-guo LIU Pain research Center of Sun Yat-sen University,Guangzhou,510080

＜正＞TTX-sensitive（TTX-S） Nav1.3 sodium channel is barely detectable in adult DRG or spinal *** nerve injury,however,the channel is up-regulated dramatically,which may contribute to neuropathic *** previous studies have shown TNF-a in DRG is increased after selective damage of motor fibers by L5 ventral root trancection（L5-VRT）.In the present work,we tested the hypothesis that TNF-a up-regulates Nav 1.3 after nerve *** found that Nav 1.3 in ipsilateral L4 and L5 DRG was increased following L5-VRT,starting on day 1,reached a peak on day 7 and persisted for at least 5 weeks after *** staining revealed that Nav 1.3 is mainly located in the C-type neurons and to a less extent in A-type neurons;More than 85%of neurons that express Nav 1.3 is TNF-α -*** confirm the relationship between TNF-α and Nav1.3,we applied TNF-α directly on to sciatic nerve without nerve injury and found that TNF-α alone produced mechanical allodynia and up-regulation of Navl.3 in DRG ***,we observed pretreatment with thalidomide,an inhibitor of TNF-α synthesis,significantly inhibited the expression of Nav 1.3 in DRG and the behavioral signs of neuropathic pain induced by *** conclude that apart from transient activation of sensory neurons as reported previously,TNF-α may produce long-lasing excitability change of neurons by up-regulation of Nav 1.3.

关键词： TNF-α Nav1.3 neuropathic pain dorsal root ganglion

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Journal of Wuhan University of Technology(Materials Science) 2025年第1期40卷 103-113页

作者： CHEN Wuxing CHEN Shuang YU Yan ZHANG Jiangyi XU Haiyang guo wei School of Mines China University of Mining and TechnologyXuzhou 221000China College of Construction Engineering Jilin Uni-versityChangchun 130026China

The pre-wetting of aggregate surface is a means to improve the interface performance of SBS modified asphalt and *** effect of pre-wetting technology on the interaction between SBS modified asphalt and aggregate was analyzed by molecular dynamics *** diffusion coefficient and concentration distribution of SBS modified asphalt on aggregate surface are *** simulation results show that the diffusion coefficient of the aggregate surface of SBS modified asphalt is increased by 47.6%and 70.5%respectively after 110#asphalt and 130#asphalt are *** concentration distribution of SBS modified asphalt on the aggregate surface after pre-wetting is more *** to the results of interface energy calculation,the interface energy of SBS modified bitumen and aggregate can be increased by about 5%after *** to the results of molecular dynamics simulation,the pre-wetting technology can effectively improve the interface workability of SBS modified bitumen and aggregate,so as to improve the interface performance.

关键词： pre-wet oil-stone interface interface interaction interface mechanics molecular dynamics simulation

基于非线性振动的联轴器膜盘振动疲劳试验研究

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实验力学 2016年第6期31卷 763-768页

作者：杨宪峰许巍郭广平北京航空材料研究院材料检测与评价航空科技重点实验室航空材料检测与评价北京市重点实验室先进高温结构材料国防科技重点实验室北京100095

介绍了航空发动机联轴器TC4钛合金膜盘振动疲劳的试验研究。通过建立闭环控制下的振动疲劳试验系统,得到了该膜盘在不同激励条件下的频率-位移响应曲线,由此阐明了联轴器膜盘在大挠度条件下的非线性振动特性。基于该特性进一步开展膜盘... 详细信息

介绍了航空发动机联轴器TC4钛合金膜盘振动疲劳的试验研究。通过建立闭环控制下的振动疲劳试验系统,得到了该膜盘在不同激励条件下的频率-位移响应曲线,由此阐明了联轴器膜盘在大挠度条件下的非线性振动特性。基于该特性进一步开展膜盘在非线性振动条件下的振动疲劳试验研究,给出了该膜盘的径向应力-疲劳寿命曲线以及疲劳极限值。最后分析了膜盘振动疲劳的主要破坏形式。结果表明,膜盘疲劳极限值介于其母体材料的中值疲劳极限值和高可靠度疲劳极限值之间,而主要破坏形式包括可见表面裂纹和表面剥落。

关键词：联轴器膜盘非线性振动振动疲劳

A Rapid Adaptation Approach for Dynamic Air‑Writing Recognition Using Wearable Wristbands with Self‑Supervised Contrastive Learning

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Nano-Micro Letters 2025年第2期17卷 417-431页

作者： Yunjian guo Kunpeng Li wei Yue Nam‑Young Kim Yang Li guozhen Shen Jong‑Chul Lee Department of Electronic Convergence Engineering Kwangwoon UniversitySeoul 01897South Korea Radio Frequency Integrated Circuit(RFIC)Bio Centre Kwangwoon UniversitySeoul 01897South Korea Department of Electronic Engineering Kwangwoon UniversitySeoul 01897South Korea School of Microelectronics Shandong UniversityJinan 250101People’s Republic of China State Key Laboratory of Integrated Chips and Systems Fudan UniversityShanghai 200433People’s Republic of China School of Integrated Circuits and Electronics Beijing Institute of TechnologyBeijing 100081People’s Republic of China

Wearable wristband systems leverage deep learning to revolutionize hand gesture recognition in daily *** existing approaches that often focus on static gestures and require extensive labeled data,the proposed wearable wristband with selfsupervised contrastive learning excels at dynamic motion tracking and adapts rapidly across multiple *** features a four-channel sensing array composed of an ionic hydrogel with hierarchical microcone structures and ultrathin flexible electrodes,resulting in high-sensitivity capacitance *** wireless transmission from a Wi-Fi module,the proposed algorithm learns latent features from the unlabeled signals of random wrist ***,only few-shot labeled data are sufficient for fine-tuning the model,enabling rapid adaptation to various *** system achieves a high accuracy of 94.9%in different scenarios,including the prediction of eight-direction commands,and air-writing of all numbers and *** proposed method facilitates smooth transitions between multiple tasks without the need for modifying the structure or undergoing extensive task-specific *** utility has been further extended to enhance human–machine interaction over digital platforms,such as game controls,calculators,and three-language login systems,offering users a natural and intuitive way of communication.

关键词： Wearable wristband Self-supervised contrastive learning Dynamic gesture Air-writing Human-machine interaction

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减阻增程弹道的射程估算与特性分析

宇航学报 2017年第10期38卷 1048-1056页

作者：凌王辉鲜勇郭玮林李杰张大巧火箭军工程大学七系西安710025

为实现弹道导弹射程的快速估算和减阻设计后弹道增程的定量分析,提出一种基于导弹基本参数的射程快速精确估算方法。通过建立减阻模型,仿真计算得到气动阻力系数表,并对速度计算公式进行逐项积分,利用高度近似值和气动系数拟合结果得到... 详细信息

为实现弹道导弹射程的快速估算和减阻设计后弹道增程的定量分析,提出一种基于导弹基本参数的射程快速精确估算方法。通过建立减阻模型,仿真计算得到气动阻力系数表,并对速度计算公式进行逐项积分,利用高度近似值和气动系数拟合结果得到关机点状态量和射程的初步值,最终通过迭代计算得到满足精度要求的射程结果。仿真结果表明,经过高度和气动系数的迭代计算能有效快速得到满足精度的计算结果,通过减阻设计,导弹射程提高了162.36 km,增程的效果明显。

关键词：减阻设计弹道增程射程快速估算气动拟合迭代计算

Activation of translocator protein（TSPO） reverses neuropathic pain behavior

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Activation of translocator protein（TSPO） reverses neuropat...

High-performance poly(aromatic pyridine) copolymers with crown ether moieties for high temperature polymer electrolyte membrane fuel cells

中国神经科学学会第九届全国学术会议暨第五次会员代表大会

作者： Xu-Hong wei,Li-Jun ZHOU,Cui-Cui LIU,Xiao wei,xian-guo LIU~* Pain Research Center of Sun Yat-sen University,Guangzhou 510080,China

＜正＞Neuropathic pain is characterized by a heightened painful response to noxious（hyperalgesia） or innocuous（allodynia） stimulation,and pain at rest（spontaneous pain）.At present no effective drug is available for the clinical symptom.A recent study has shown that the translocator protein（TSPO,18 kDa）,a peripheral receptor for benzodiazepine,modulates pain behaviors of rats induced by *** the present study,we evaluated the role of TSPO in neuropthic pain produced by L5 spinal nerve ligation（L5 SNL） with use of behavioral testing, immunohistochemistry and Western blot *** found that TSPO was up-regulated in spinal dorsal horn following L5 SNL and the change lasted until behavioral signs of neuropathic pain diminished（around 50 d）.Double immunofluorescence showed that in naive rats,TSPO was located mainly in astrocytes,to a lesser extent in neurons, but not in microglia,whereas following L5 SNL,TSPO was upregulated in astrocytes and microglia,but not in *** data showed that single intrathecal injection of TSPO agonist Ro5-4864 or FGIN-1-27 reversed established mechanical allodynia induced by L5 SNL *** and Western blot showed that intrathecal injection of Ro5-4864 reversed activation of astrocytes,and depressed p38 MAPK activation,which is exclusively activated in spinal microglial cells following peripheral nerve *** data suggested that activation of TSPO by agonists might reverse neuropathic pain by inhibition of activated glial cells.

关键词： TSPO neuropathic pain astrocyte

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Science China Chemistry 2025年

作者： Qian Wang Songhao Zhao Yunpeng guo wei wei Lele Wang Jingshuai Yang Department of Chemistry College of Sciences Northeastern University Institute of Metal Research Chinese Academy of Sciences

This study concentrates on the development of high temperature polymer electrolyte membranes（HT-PEMs）, which are essential components for HT-PEM fuel cells（HT-PEMFCs）. Although the phosphoric acid（PA）-doped polybenzimidazole（PBI） has been regarded as the successful HT-PEM, this system still suffers from several challenges, including the use of carcinogenic monomers, complex synthesis procedures, and poor solubility in organic solvents. To develop more cost-effective, readily synthesized and high-performance alternatives, this study employs a simply superacid-catalyzed Friedel-Crafts reaction to synthesize a series of poly（triphenyl-co-dibenzo-18-crown-6 pyridine） copolymers, denoted as P(TPx%-co-CEy%), using ptriphenyl, dibenzo-18-crown-6 and 4-acetylpyridine as monomers. The copolymerized hydrophilic and bulky crown ether unites introduce large free volumes and multiple interaction sites with PA molecules, as elucidated by theoretical *** microphase separation structures are formed as confirmed by atomic force microscope（AFM）, transmission electron microscopy（TEM） and small-angle X-ray scattering（SAXS）. Thus P(TPx%-co-CEy%) membranes exhibit excellent PA absorption and proton conduction abilities. For example, after immersing in 85 wt% PA at 30 °C, the P(TP91%-co-CE9%) membrane achieves a PA doping content of 205% and a high conductivity of 0.138 S cm-1at 180 °C, while maintaining a tensile strength of 7.5 MPa at room temperature. Without humidification and backpressure, the peak power density of an H2-O2cell equipped with P(TP91%-co-CE9%)/205%PA reaches nearly 1200 mW cm-2, representing one of the highest performances reported for PA-doped HT-PEMs to date. This work demonstrates the enormous potential of poly（triphenyl-co-crown ether pyridine） membranes in the HT-PEMFC applications.

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