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An integrated machine-process-controller model to predict milling surface topography considering vibration suppression

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Advances in Manufacturing 2022年第3期10卷 443-458页

作者： Miao-xian Guo Jin Liu Li-mei Pan Chong-Jun Wu Xiao-Hui Jiang Wei-Cheng Guo College of Mechanical Engineering University of Shanghai for Science and TechnologyShanghai 200093People's Republic of China College of Mechanical Engineering Donghua UniversityShanghai 201620People's Republic of China

Surface topography is an important factor in evaluating the surface integrity and service performance of milling *** dynamic characteristics of the manufacturing system and machining process parameters significantly influence the machining precision and surface quality of the parts,and the vibration control method is applied in high-precision milling to improve the machine *** this study,a novel surface topography model based on the dynamic characteristics of the process system,properties of the cutting process,and active vibration control system is theoretically developed and experimentally *** dynamic characteristics of the process system consist of the vibration of the machine tool and piezoelectric ceramic clamping *** dynamic path trajectory influenced by the processing parameters and workpiece-tool parameters belongs to the property of the cutting process,while different algorithms of active vibration control are considered as controller *** milling surface topography can be predicted by considering all these factors.A series of experiments were conducted to verify the effectiveness and accuracy of the prediction model,and the results showed a good correlation between the theoretical analysis and the actual milled surfaces.

关键词： Machine-process-controller Milling surface topography Vibration suppression Prediction model

Stereoselective Synthesis of δd-Selanyl Allylic Alcohols by Hydrozirconation of Propargyl Selenides

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Chinese Chemical Letters 2003年第3期14卷 255-256页

作者： mei Hua XIE xian HUANG 等 DepartmentofChemistry ZhejiangUniversityXi-xiCampushangzhou310028 StateKeyLaboratoryofOrganometallicChemistry ShanghaiInstituteofOrganicChemistryChineseAcademyofSciencesShanghai

Hydrozirconation of propargyl selenides afford (E)-3-selanyl vinylzirconocenes chlorides 2. Intermediates 2 reacted with aldehydes to obtain d-selanyl allylic alcohols.

关键词： Hydrozirconation propargyl selenides aldehydes allylic alcohols.

The Mechanism of Total Ginseng Extracts in the Treatment of Lung Cancer Progression Based on Network Pharmacology and Experimental Validation

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World Journal of Traditional Chinese Medicine 2023年第3期9卷 284-296页

作者： Hong-Kuan Han Cheng Qian meng-Yao Song Teng Zhang Chun-mei Yang Ren-Jun Gu xian Zhou Zhong-Hong Wei Yang Zhao Yin Lu Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica School of PharmacyNanjing University of Chinese MedicineNanjngChina Jiangsu Joint International Research Laboratory of Chinese Medicine and Regenerative Medicine Nanjing University of Chinese MedicineNanjingChina Department of Biochemistry and Molecular Biology School of Medicine and Holistic Integrative MedicineNanjing University of Chinese MedicineNanjingChina School of Chinese Medicine School of Integrated Chinese and Western MedicineNanjing University of Chinese MedicineNanjingChina NICM Health Research Institute Western Sydney UniversityWestmeadNSWAustralia

Objective:The objective of this study was to investigate the mechanism by which total ginseng extract(TGE)inhibits the progression of lung cancer through network pharmacology and *** and Methods:A Lewis lung carcinomas(LLC)model was established by injecting cancer cells through the tail vein and through administering different doses of *** infiltrated immune cells into the microenvironment of lung cancer metastasis through flow cytometry were evaluated,and the messenger RNA(mRNA)expression levels of various immune cell-related chemokines were determined using quantitative reverse transcription–polymerase chain *** targets and signaling pathways of TGE in nonsmall cell lung cancer were investigated using systematic pharmacology and virtual *** was performed to determine the impacts of TGE on migration-related ***:Flow cytometry showed that 1.82 g/kg TGE increased the infiltrated T cells and inhibited the recruitment of myeloid cells,which was caused by decreased mRNA expression of chemokines after TGE *** ontology and Kyoto Encyclopedia of Genes and Genomes analyses showed that the delayed progression of lung cancer by TGE might be related to the promotion of lung cancer cell apoptosis-associated signaling *** virtual docking results indicated that the active components of ginseng are directly bound to apoptosis-related *** showed that TGE inhibited tumor metastasis by regulating the expression of migration-related ***:The study reveals the potential mechanism of ginseng extract in the treatment of lung cancer progression and provides a reliable basis for its clinical application.

关键词： Ginseng lung cancer mechanism metastasis network pharmacology

Hydrocarbon generation history constrained by thermal history and hydrocarbon generation kinetics:A case study of the Dongpu Depression,Bohai Bay Basin,China

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Petroleum Science 2022年第2期19卷 472-485页

作者： mei-Hua Yang Yin-Hui Zuo Kang-Nan Yan Yong-Shui Zhou Yun-xian Zhang Cheng-Fu Zhang State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation Chengdu University of TechnologyChengduSichuan 610059China Energy&Geoscience Institute University of UtahSalt Lake CityUT84108USA Research Institute of Exploration and Development Zhongyuan OilfieldSINOPECPuyangHenan 457001China

With the increasing exploration and development of typical hydrocarbon-rich depressions,such as the Dongpu Depression,the exploitation difficulty of shallow formations is *** is an urgent need to clarify the hydrocarbon generation mode and hydrocarbon generation histories in deep *** this study,a gold tube-autoclave closed system was used to simulate the hydrocarbon generation processes and establish the hydrocarbon generation mode of different types of ***,constrained by the thermal history and hydrocarbon generation kinetics,hydrocarbon generation histories were *** results show that hydrocarbon generation evolution can be divided into five stages,and the maturity of each stage is *** hydrocarbon generation history of the source rocks of the Shahejie 3 Formation mainly dates from the early depositional period of the Shahejie 1 Formation to the middle depositional period of the Dongying *** generation history constrained by thermal history and hydrocarbon generation kinetics is more in line with actual geological ***,this research can provide important hydrocarbon generation parameters for deep oil and gas exploration and exploitation of the Shahejie 3 Formation in the Dongpu Depression.

关键词： Dongpu depression Thermal history Hydrocarbon generation kinetics Hydrocarbon generation mode Hydrocarbon generation history

A Top-Down Approach towards Cu(I)Alkynyl Clusters with Unusual Geometry

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Chinese Journal of Chemistry 2021年第4期39卷 937-941页

作者： Huan Li Ting Li Shuimiao Liu mei Qu Linfeng Liang Fengwei Zhang xian-Ming Zhang Institute of Crystalline Materials Shanxi UniversityTaiyuanShanxi030006 China School of Chemistry and Material Science Shanxi Normal UniversityLinfenShanxi041004 China

Main observation and conclusion To search for novel Cu(I)complexes,traditional approaches focus on designing and screening ligands,metal precursors and reaction *** this report,we propose a top-down approach,in which ... 详细信息

关键词： Copper Top-down Cluster Fluorescence Alkynyl

Stepwise assembly of heterometallic 3d–4f chain exhibiting slow magnetic relaxation

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Chinese Chemical Letters 2016年第3期27卷 317-320页

作者： mei-Hui Yu Xue Jiang Song-De Han Qing-Lun Wang xian-He Bu School of Materials Science and Engineering TKL of Metal- and Molecule-Based Material Chemistry and Collaborative Innovation Center of Chemical Science and Engineering (Tianjin)Nankai University Department of Chemistry Nankai University

The self-assembly of polyalcohol ligand 1,1,1-tris（hydroxymethyl）ethane with Dy（NO3）3· 6H2 O and Cr3O-Bzo-t-Bu precursor in the presence of triethylamine step-by-step generated a heterometallic 3d–4f chain. Magn... 详细信息

关键词： 3d–4f Chain Stepwise assembly Slow magnetic relaxation

Effect of Cooling Method on Microstructure and Mechanical Properties of Hot-Rolled C-Si-Mn TRIP Steel

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Journal of Iron and Steel Research International 2012年第1期19卷 41-46页

作者： LIU Ji-yuan ZHANG Zi-cheng ZHU Fu-xian LI Yan-mei Manabe Ken-ichi State Key Laboratory of Rolling and Automation Northeastern UniversityShenyang 110004LiaoningChina Department of Mechanical Engineering Tokyo Metropolitan UniversityTokyo 192-0397Japan

The controlled cooling technology following hot rolling process is a vital factor that affects the final micro- structure and mechanical properties of the hot-rolled transformation induced plasticity （TRIP） steels. In the present study, low alloy C-Si-Mn TRIP steel was successfully fabricated by hot rolling process with a 4450 hot roiling mill. To maximize the volume fraction and stability of retained austenite of the steel, two different cooling methods （aircooling and ultra-fast cooling ＂AC-UFC＂ and ultrmfast cooling, air cooling and ultra-fast cooling ＂UFC-AC-UFC＂） were conducted. The effects of the cooling method on the microstructure of hot-rolled TRIP steel were investigated via optical microscope, transmission electron microscope and conversion electron Mossbauer spectroscope. The mechanical properties of the steel were also evaluated by conventional tensile test. The results indicated that ferrite and bainite in the microstructure were refined with the cooling method of UFC-AC-UFC. The morphology of retained austenite was also changed from small islands distributing in bainite district （obtained with AC-UFC） to granular shape locating at the triple junction of the ferrite grain boundaries （obtained with UFC-AC-UFC）. As a result, the TRIP steel with a content of retained austenite of 11. 52%, total elongation of 32% and product of tensile strength and total elongation of 27 552 MPa·% was obtained.

关键词： hot-rolled TRIP steel retained austenite TRIP effect Mossbauer spectra mechanical property

Observation of the effects of three methods for reducing perineal swelling in children with developmental hip dislocation

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World Journal of Clinical Cases 2020年第20期8卷 4719-4725页

作者： Ling Wang Ning Wang mei-Ying He Hai-Lun Liu xian-Qiang Wang Department of Pediatric Surgery Chinese PLA General HospitalBeijing 100853China

BACKGROUND Developmental dysplasia of the hip is a developmental abnormality of the hip joint that results from hypoplasia during birth and continues to deteriorate after *** To observe the effects of magnesium sulfate wet compress,iodophor wet compress,and ice compress on reducing postoperative perineal swelling in children with developmental hip dislocation to provide effective nursing interventions in the *** A total of 120 children with hip dislocation after surgery in a third-class A hospital from January 2018 to January 2020 were randomly divided into four groups,the magnesium sulfate wet compress group,iodophor wet compress group,ice compress group and the control *** such as height,weight,age,duration of surgery,intraoperative blood loss,postoperative body temperature,swelling duration,pain score,and incidence of blisters were collected and *** There were no significant differences in height,weight,age,duration of surgery,intraoperative blood loss,and postoperative body temperature among the four groups of *** differences were observed between the intervention groups and the control group(P<0.05).CONCLUSION All three methods significantly reduced postoperative perineal swelling in children with developmental hip dislocation,reduced the duration of postoperative perineal swelling,reduced pain,and improved the quality of care.

关键词： Pediatric surgery Developmental hip dislocation Pediatric care Postoperative complications Perineal swelling

Double-edged effect of sodium citrate in Nile tilapia(Oreochromis niloticus):Promoting lipid and protein deposition *** hyperglycemia and insulin resistance

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Animal Nutrition 2023年第3期14卷 303-314页

作者： Jun-xian Wang Fang Qiao mei-Ling Zhang Li-Qiao Chen Zhen-Yu Du Yuan Luo Laboratory of Aquaculture Nutrition and Environmental Health(LANEH) School of Life SciencesEast China Normal UniversityShanghaiChina

Citrate is an essential substrate for energy metabolism that plays critical roles in regulating glucose and lipid metabolic ***,the action of citrate in regulating nutrient metabolism in fish remains poorly ***,we investigated the effects of dietary sodium citrate on growth performance and systematic energy metabolism in juvenile Nile tilapia(Oreochromis niloticus).A total of 270Nile tilapia(2.81±0.01 g)were randomly divided into three groups(3 replicates per group,30 fish per replicate)and fed with control diet(35%protein and 6%lipid),2%and 4%sodium citrate diets,respectively,for 8 *** results showed that sodium citrate exhibited no effect on growth performance(P>0.05).The whole-body crude protein,serum triglyceride and hepatic glycogen contents were significantly increased in the 4%sodium citrate group(P0.05).The 4%sodium citrate treatment significantly increased the serum glucose and insulin levels at the end of feeding trial and also in the glucose tolerance test(P<0.05).The 4%sodium citrate significantly enhanced the hepatic phosphofructokinase activity and inhibited the expression of pyruvate dehydrogenase kinase isozyme 2 and phosphor-pyruvate dehydrogenase E1 component subunit alpha proteins(P<0.05).Additionally,the 4%sodium citrate significantly increased hepatic triglyceride and acetyl-Co A levels,while the expressions of carnitine palmitoyl transferase 1a protein were significantly down-regulated by the 4%sodium citrate(P<0.05).Besides,the 4%sodium citrate induced crude protein deposition in muscle by activating m TOR signaling and inhibiting AMPK signaling(P<0.05).Furthermore,the 4%sodium citrate significantly suppressed serum aspartate aminotransferase and alanine aminotransferase activities,along with the lowered expression of pro-inflammatory genes,such as nfκb,tnfa and il8(P<0.05).Although the 4%sodium citrate significantly increased phosphor-nuclear factor-k B p65 prote

关键词： Sodium citrate Lipid and protein deposition Insulin resistance Nile tilapia