检索结果-南通市图书馆

Effect of Cooling Patterns on Microstructure and Mechanical Properties of Hot-Rolled Nb Microalloyed Multiphase Steel Plates

在线全文

学校读者我要写书评

暂无评论

Journal of Iron and Steel Research International 2011年第8期18卷 46-52页

作者： ZHENG Dong-sheng ZHU Fu-xian LI Yan-mei CHEN Bing-zhang Nanjing Iron and Steel United Co Ltd Nanjing 210035 Jiangsu China State Key Laboratory ofRolling and Automation Northeastern University Shenyang 110819 Liaoning China

The effect of the run-out table cooling patterns on the microstructure and mechanical properties of Nb microalloyed steel plates was investigated by hot rolling experiment. The results showed that the mixed microstrueture containing ferrite, bainite and significant amounts of retained austenite can be obtained through three kinds of cooling patterns on the run-out table under the same hot rolling condition. Three kinds of cooling patterns possess different austenite transformation kinetics, which leads to variations in microconstituent characteristics. The yield strength increases, the tensile strength decreases and the total elongation tends to increase as the cooling patterns Ⅰ , Ⅱ and Ⅲ were applied respectively. The yield strength, the total elongation and the product of tensile strength and ductility reach the maximum values （547 MPa, 37. 2% and 28 384 MPa% respectively） for the steel plate processed by cooling pattern Ⅲ.

关键词： Nb microalloyed steel hot-rolled multiphase steel cooling pattern microstructure mechanical property

A new lignan derivative from the root of Ilex pubescens

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2008年第5期19卷 550-552页

作者： Yu Bo Zhou Jin Hui Wang xiang mei Li xian Li School of Traditional Chinese Materia Medica Shenyang Pharmaceutical University Shenyang 110016 China

One new compound, ilexlignan A （1）, was isolated from the root of llex pubescens. Its structure was elucidated by the combination of one- and two-dimensional NMR analysis, mass spectrometry, CD spectrum measurement ... 详细信息

关键词： llex pubescens llexlignan A Lignan

The flame retardancy of alginate/flame retardant viscose fibers investigated by vertical burning test and cone calorimeter

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2018年第3期29卷 489-492页

作者： xian-Sheng Zhang Yan-Zhi Xia mei-Wu Shi Xiong Yan Key Laboratory of Textile Science & Technology Ministry of Education College of Textiles Donghua University Shanghai 201620 China Laboratory of Fiber Materials and Modern Textile The Growing Base for State Key Laboratory Qingdao University Qingdao 266071 China The Quartermaster Equipment Research Institute of Logistical Support Department Beijing 100082 China

In this research, the flame retardancy of neat alginate fiber, flame retardant viscose fiber （FRV） and alginate/FRV （50/50） blending fibers were investigated by vertical burning and cone calorimeter tests. The vertical burning test showed that the afterflame time of alginate fiber was 0 s, but alginate presented serious smoldering behavior with the afterglow time of 605 s and damaged length of 85 mm, while the afterglow time of FRV was 0 s. When the FRV was incorporated into alginate with the weight ratio of 50/ 50, the afterglow time and damaged length were significantly reduced to 85 s and 35 mm, indicating the smoldering of alginate can be effectively decreased. The morphology and chemical structure of the alginate residual demonstrated that it was seriously destroyed during smoldering process, which was ascribed to its relative low initial thermal degradation temperature. Based on the thermal properties analysis, alginate and FRV fibers shared the concurrence of rapid degradation in the same temperature region of 250-300 ℃, through which, the compact and stable char formed by FRV can prevent the heat transmission and suppress the smoldering of alginate. Further, the cone calorimeter results demonstrated that the time to ignition （TTI） significantly increased and peak heat release rate （PHRR） decreased for alginate/FRV （50/50） compared with FRV. With this research, a new method to overcome the smoldering of alginate was proposed by blending with FRV

关键词： Alginate fibers Flame retardant viscose fibers Blending Flame retardancy Vertical burning test Cone calorimeter

Effect of Austenite Recrystallization on Microstructure and Properties of Q345 Steel

在线全文

学校读者我要写书评

暂无评论

Journal of Iron and Steel Research International 2005年第5期12卷 39-46页

作者： ZHU Fu-xian LI Yan-mei LIU Yan-chun WANG Guo-dong Northeastern University Shenyang 110004 China

The Q345 plate steel austenite recrystallization behavior and strain accumulation during rolling were investigated through thermal simulation and rolling. The effect of the recrystallization behavior on the microstructure and properties of the steel was discussed and analyzed. The control principles of the pass reduction in the austenite recrystallization region and partial recrystallization region were established. It is found that to increase the thickness of intermediate billet in the finish temperature interval of 880-820℃ is favorable to grain refinement. The result has been applied to the industrial production of the 3 500 mm plate mill of Shougang Group. The average grain size of the steel plate conforms to ASTM No. 10-12, and the grade of band structure has been reduced to below 1.5.

关键词： Q345 steel plate steel austenite recrystallization strain accumulation effect TMCP grain refinement

Resistin does not down-regulate the transcription of insulin receptor promoter

在线全文

学校读者我要写书评

暂无评论

Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2008年第4期9卷 313-318页

作者： Xiao-zhi QIAO xian-feng WANG Zhe-rong XU Yun-mei YANG Department of Very Important Person the First Affiliated Hospital School of Medicine Zhejiang University Hangzhou 310003 China Institute of Infectious Diseases the First Affiliated Hospital School of Medicine Zhejiang University Hangzhou 310003 China

Objective: To detect the effect of resistin on the transcription of insulin receptor promoter. Methods: Luciferase reporter gene was fused downstream of human insulin receptor promoter and the enzymatic activity of luciferase was determined in the presence or absence of resistin. The resistin expressed with plasmid was stained with antibody against Myc tag which was in frame fused with resistin coding sequence, and then imaged with confocal microscopy. Results: The treatment of pIRP-LUC transfected cells with recombinant resistin did not result in significant difference in the enzymatic activity of luciferase compared to the untreated cells. Cell staining showed that green fluorescence could be observed in the cytoplasm, but not in the nucleus. Conclusion: The results suggest that the endogenous resistin may functionally locate in the cytoplasm, but does not enter the nucleus and not down-regulate the transcription of insulin receptor promoter.

关键词： Resistin Insulin receptor promoter Luciferase reporter gene

A unique 3D microporous MOF constructed by cross-linking 1D coordination polymer chains for effectively selective separation of CO_(2)/CH4 and C_(2)H_(2)/CH_(4)

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2021年第3期32卷 1153-1156页

作者： Yu-Pei Xia Chen-Xue Wang mei-Hui Yu xian-He Bu School of Materials Science and Engineering National Institute for Advanced MaterialsNankai UniversityTianjin 300350China State Key Laboratory of Elemento-Organic Chemistry College of ChemistryNankai UniversityTianjin 300071China

Selective separation of CO_(2)/CH_(4)and C2 H_(2)/CH_(4)are promising for their high-purity industrial demand and scientific research on account of the similar molecular radius and physical *** this work,a unique 3 D microporous MOF material[Cu(SiF6)(sdi)2]·solvents(1,sdi=1,1’-sulfonyldiimidazole)was successfully constructed by cross-linking 1 D coordination polymer *** dense functional active sites on the inner walls of the channel of la can provide strong binding affinities to CO_(2),C2 H_(2),and thus effectively improve the gas separation performance of CO_(2)/CH_(4)and C2 H_(2)/CH_(4).

关键词： Metal-organic framework Cross-linking Selective separation Dense functional active site

A microfluidic cell chip for virus isolation via rapid screening for permissive cells

在线全文

学校读者我要写书评

暂无评论

Virologica Sinica 2022年第4期37卷 547-557页

作者： Weide Su Jingjiang Qiu Ying mei xian-En Zhang Yong He Feng Li State Key Laboratory of Virology Wuhan Institute of VirologyCenter for Biosafety Mega-ScienceChinese Academy of SciencesWuhan430071China School of Mechanics and Safety Engineering Zhengzhou UniversityZhengzhou450001China Faculty of Synthetic Biology Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen518055China National Laboratory of Biomacromolecules Institute of BiophysicsChinese Academy of SciencesBeijing100101China State Key Laboratory of Fluid Power and Mechatronic Systems School of Mechanical EngineeringZhejiang UniversityHangzhou310027China University of Chinese Academy of Sciences Beijing100049China Current address:Wuhan Institute of Biological Products Co. Ltd.Wuhan430070China

Virus identification is a prerequisite not only for the early diagnosis of viral infectious diseases but also for the effective prevention of *** cultivation is the gold standard for identifying a virus,according to the Koch ***,this requires screening for a permissive cell line,which is traditionally time-,reagent-and ***,a simple and easy-to-operate microfluidic chip,formed by seeding a variety of cell lines and culturing them in parallel,is reported for use in virus cultivation and virus-permissive host-cell *** chip was tested by infection with two known viruses,enterovirus 71(EV71)and influenza virus *** with EV71 and H1N1 caused significant cytopathic effects(CPE)in RD and MDCK cells,respectively,demonstrating that virus cultivation based on this microfluidic cell chip can be used as a substitute for the traditional plate-based culture method and reproduce the typical CPE caused by virus *** this microfluidic cell chip method for virus cultivation could make it possible to identify an emerging virus in a highthroughput,automatic,and unprecedentedly fast way.

关键词： Virus cultivation Microfluidic cell chip Permissive cell Enterovirus 71(EV71) Influenza virus

Exosome-Transmitted miR-224-5p Promotes Colorectal Cancer Cell Proliferation via Targeting ULK2 in p53-Dependent Manner

在线全文

学校读者我要写书评

暂无评论

Biomedical and Environmental Sciences 2024年第1期37卷 71-84页

作者： YANG Le mei ZHENG Qi LIU Xiao Jia LI xian xian Veronica Lim CHEN Qi ZHAO Zhong Hua WANG Shu Yang Department of Pathology School of Basic MedicineFudan UniversityShanghai 200032China Department of Pathology Dunedin School of MedicineUniversity of OtagoDunedin 9054New Zealand Department of Pathology Huashan HospitalFudan UniversityShanghai 200040China Shanghai Cancer Institute Renji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200127China Teladoc Health Inc Shanghai 200335China Shanghai Medical College Fudan UniversityShanghai 200032China Shanghai Key Laboratory of Medical Imaging Computing and Computer Assisted Intervention Shanghai 200032China

Objective To investigate the role and molecular mechanism of exosomal miR-224-5p in colorectal cancer(CRC).Methods The miR-224-5p expression in CRC patient tissues and cell-derived exosomes was measured by laser capture microdissection and qRT-PCR,***-luciferase reporter gene assay was used to determine the target gene of *** protein expressions of p53 and unc-51 like kinase 2(ULK2)in CRC cells were detected by western *** cytometry was used to detect cell cycle and *** proliferation was measured by CCK8 and EdU *** The miR-224-5p expression was upregulated in CRC tissues and increased progressively with the rise of CRC *** cells secreted extracellular miR-224-5p mainly in an exosome-dependent manner,and then miR-224-5p could be transferred to surrounding tumor cells to regulate cell proliferation in the form of autocrine or ***,ULK2 was characterized as a direct target of miR-224-5p and was downregulated in CRC ***,ULK2 inhibited CRC cell proliferation in a p53-dependent ***,exosome-derived miR-224-5p partially reversed the proliferation regulation of ULK2 on CRC *** Our findings demonstrate that exosome-transmitted miR-224-5p promotes p53-dependent cell proliferation by targeting ULK2 in CRC,which may offer promising targets for CRC prevention and therapy.

关键词： miR-224-5p Exosome ULK2 p53 Cell proliferation Colorectal cancer

Toughening of Polycarbonate through Reactive Melt Blending: Effect of Hydroxyl Content and Viscosity of Hydroxyl-terminated Polydimethysiloxane

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Polymer Science 2014年第7期32卷 823-833页

作者： Shuang-mei Zhang Hui-xian Zhang Wei-yi Zhang Zhi-qiang Wu Feng Chen 傅强 College of Polymer Science and Engineering State Key Laboratory of Polymer Materials EngineeringSichuan University State Key Laboratory of Molecular Engineering of Polymers and Department of Macromolecular Science Fudan University

In this study, four hydroxyl-terminated polydimethylsiloxanes （PDMSOH） with different viscosities and hydroxyl contents were used to improve the toughness of polycarbonate （PC） through reactive melt blending. A largely improved toughness of PC has been achieved, and the low temperature toughness of PC/PDMSOH blends could overtake that of PC homopolymer in much higher temperatures （e.g. -10 ~C versus 23 ~C）. Moreover, it was found that the more the hydroxyl content, the less the PDMSOH was needed to reach the highest toughness, suggesting that equivalent molar ratio between the carbonyl group content of PC and the hydroxyl group content of PDMSOH was required for the toughening of PC. Ultraviolet spectrophotometry was used to analyze the possible reaction between PC and PDMSOH. Contact angle was measured to assess the change of interfacial interaction between PC and PDMSOH as change of viscosity and hydroxyl content. The formation of PC-co-PDMSOH copolymer was believed to be the key for the toughening effect. This work gives a profound recommendation of the optimum kind and dosage of PDMSOH which should be used to improve the toughness of PC and will find immediate industrial applications.

关键词： Blends Low temperature toughness Polycarbonate Polydimethylsiloxane.