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考虑不同光伏渗透率影响的配电网风险规划研究

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机电工程 2016年第5期33卷 595-601页

作者：叶斌李万启王绪利葛斐熊世旺周贤正郭创新国家电网安徽省电力公司经济技术研究院安徽合肥230022 浙江大学电气工程学院浙江杭州310027

针对含光伏电源的配电网规划问题,考虑光伏输出特性受天气影响和因此造成配网潮流方向的改变和产生电压偏差等影响因素,提出了一种考虑不同光伏渗透率和电网运行风险的配电网规划方法。将天气状态大致归为3类,得到3种典型的光伏出力曲... 详细信息

针对含光伏电源的配电网规划问题,考虑光伏输出特性受天气影响和因此造成配网潮流方向的改变和产生电压偏差等影响因素,提出了一种考虑不同光伏渗透率和电网运行风险的配电网规划方法。将天气状态大致归为3类,得到3种典型的光伏出力曲线。采用两状态天气模型,用不同天气条件下的线路故障率和光伏出力来表征天气状况对网架线路规划方案的影响,并通过系统切负荷期望值评估了规划方案的运行风险。提出了用于对不同光伏渗透率下规划方案经济性进行了评估的光伏发电投资收益比,综合给出合理的规划方案,并用不同的配电规划系统进行了测试。研究结果表明,光伏渗透率对光伏投资收益比和网架线路规划有重要影响。

关键词：配电网规划风险规划光伏渗透率天气状态故障概率模型

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核级石墨密封垫片应力补偿机理研究

压力容器 2017年第11期34卷 41-46,54页

作者：吴延泽周先军吉日木图刁晓勇程增康黄志强中国石油大学(华东)机电工程学院山东青岛266580 滨州双峰石墨密封材料有限公司山东东营256615

以核级石墨密封垫片为研究对象,对垫片的压缩回弹性能以及密封性能进行试验研究,并采用ANSYS有限元软件对法兰连接进行仿真模拟,分析垫片在常温及高温工况下的应力分布规律,研究垫片的应力补偿机理。研究结果表明,预紧时石墨环和金属外... 详细信息

以核级石墨密封垫片为研究对象,对垫片的压缩回弹性能以及密封性能进行试验研究,并采用ANSYS有限元软件对法兰连接进行仿真模拟,分析垫片在常温及高温工况下的应力分布规律,研究垫片的应力补偿机理。研究结果表明,预紧时石墨环和金属外环同时承受螺栓预紧力作用,金属外环承受多余载荷并在内压升高过程中将载荷释放以起到应力补偿作用,维持垫片应力在一定承载范围内基本不变;高温工况下,压力在一定范围波动,垫片即可维持一稳定的应力状态,从而确认了垫片应力补偿机理的有效性。

关键词：核级石墨密封垫片压缩回弹性能密封性能有限元分析应力补偿机理

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结合位置指纹和行人航迹的室内定位技术

计算机系统应用 2017年第5期26卷 272-278页

作者：罗思奇罗笑玲李敏澄李志锋陈建城周娴玮潘家辉华南师范大学软件学院南海528225

主要对室内定位技术展开研究,首先通过手持智能设备收集指定范围样本点的坐标及wifi热点信息;然后应用位置指纹定位方法进行绝对定位;为了提高行走过程中定位的准确性和实时性,采用行人航迹推算算法,即通过手机传感器采集并经处理的数... 详细信息

主要对室内定位技术展开研究,首先通过手持智能设备收集指定范围样本点的坐标及wifi热点信息;然后应用位置指纹定位方法进行绝对定位;为了提高行走过程中定位的准确性和实时性,采用行人航迹推算算法,即通过手机传感器采集并经处理的数据进行步频检测、步长估算和方向检测,实现相对位置变化的估算.行人航迹算法克服位置指纹定位的不稳定性,而位置指纹定位算法及时调整行人航迹算法带来的累积误差.实验结果表明两种室内定位技术的结合有效提高了室内定位的准确性,能充分应用到实际生活中.

关键词：室内定位安卓平台 wifi 位置指纹定位行人航迹推算

成年与老年心房颤动犬钙激活中性蛋白酶表达及心房结构的比较

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中国心脏起搏与心电生理杂志 2017年第5期31卷 437-442页

作者：董丽君周贤惠李耀东张疆华邢强芦颜美汤宝鹏新疆医科大学第一附属医院心脏起搏电生理科新疆乌鲁木齐83054

目的研究在心房颤动(简称房颤)时左房肌钙激活中性蛋白酶(calpain1、calpain2)、钙蛋白酶抑素(calpastatin)与L-型电压依赖钙通道a1c亚基(LVDCC_(a1c))的表达变化,探讨房颤发生、维持的分子机制。方法健康杂种犬28只,雌雄不限。根据年... 详细信息

目的研究在心房颤动(简称房颤)时左房肌钙激活中性蛋白酶(calpain1、calpain2)、钙蛋白酶抑素(calpastatin)与L-型电压依赖钙通道a1c亚基(LVDCC_(a1c))的表达变化,探讨房颤发生、维持的分子机制。方法健康杂种犬28只,雌雄不限。根据年龄大小、节律随机分为成年窦律组、老年窦律组、成年房颤组、老年房颤组,每组各7只。各房颤组通过持续快速心房起搏建立持续性房颤犬模型。取100g左房组织,用实时荧光定量聚合酶反应(Realtime PCR)和蛋白免疫印迹(Western blot)方法检测犬calpain1、calpain2、calpastatin及LVDCC_(a1c)在mRNA和蛋白质表达水平变化。应用光镜、电镜检测细胞病理及超微结构改变,用DNA断裂的原位末端标记法(TUNEL法)检测细胞凋亡情况。结果与成年组比较,老年组LVDCC_(a1c)在mRNA和蛋白质表达水平显著地降低(P<0.05);同年龄组内与相应窦律组比较,房颤组LVDCC_(a1c)表达显著地降低(P<0.05),而calpain1表达显著地增高(P<0.05),尤其是老年房颤组增高最为明显,老年房颤组LVDCC_(a1c)与calpain1在蛋白质表达水平呈现负相关(r=-0.583,P=0.019)。与成年和窦律组比较,老年和房颤组犬心肌纤维化程度加重、细胞超微结构改变(肌原纤维退化,线粒体变性,核固缩)及凋亡指数增加。结论钙激活中性蛋白酶特异性生物活性随年龄及节律改变,可能是心房重构的分子机制之一。

关键词：心血管病学心房颤动钙激活中性蛋白酶 L-型钙通道心房结构重构

多西紫杉醇+顺铂+氟尿嘧啶方案新辅助化疗治疗进展期胃癌的Meta分析

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兰州大学学报（医学版） 2017年第5期43卷 18-26页

作者：展昊王振江杜恒锐任彦先龙勃周辉年焦作义兰州大学第二医院普外一科甘肃兰州730030

目的系统评价多西紫杉醇+顺铂+氟尿嘧啶(DCF)方案新辅助化疗在进展期胃癌治疗中的有效性和安全性。方法计算机检索PubMed、EMbase、The Cochrane Library、Web of Science、中国生物医学文献数据库、中国知网、万方数据库等,检索时限为... 详细信息

目的系统评价多西紫杉醇+顺铂+氟尿嘧啶(DCF)方案新辅助化疗在进展期胃癌治疗中的有效性和安全性。方法计算机检索PubMed、EMbase、The Cochrane Library、Web of Science、中国生物医学文献数据库、中国知网、万方数据库等,检索时限为从建库至2017年5月,搜集关于DCF方案新辅助化疗治疗进展期胃癌的随机对照试验和非随机对照试验,采用Rev Man 5.3软件进行Meta分析。结果共纳入8个研究,包括3个随机对照试验,5个非随机对照试验,576例进展期胃癌患者。Meta分析结果显示,DCF方案新辅助化疗联合手术组与直接手术组或其他方案新辅助化疗联合手术组相比,在根治性手术切除率、2年生存率方面差异有统计学意义,而有效率、1年生存率及术后并发症发生率方面差异无统计学意义。结论 DCF方案新辅助化疗可提高进展期胃癌的根治性手术切除率、延长患者的生存期,且不增加术后并发症的发生。

关键词：胃癌多西紫杉醇顺铂氟尿嘧啶新辅助化疗 Meta分析

SAPT:a synchrotron-based proton therapy facility in Shanghai

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Nuclear Science and Techniques 2023年第10期34卷 36-46页

作者： Man-zhou Zhang De-Ming Li Li-Ren Shen Hai-Rong Zhang Zhi-Ling Chen Han-Wen Du Ming Gu Rui Li De-Kang Liu Yue-Hu Pu Jun-Feng Yu Jian-Feng Chen Chu Chen Chun-Long Guo Hao Guo Ge-Yang Jiang Zhi-Qiang Jiang Lin Jin Wen-Jing Li Xiu-Fang Li Ye Lin Ming Liu Yong-Hao Liu Ya-Juan Liu Ming Lv Qing-Ru Mi Lian-Hua Ouyang Wei-Guo Shi Hang Shu Qi-Sheng Tang Kun Wang Zhi-Shan Wang Jun Wu Xiao-Bing Wu Jia-Qiang Xu Wen-Zhen Xu Chong-xian Yin Cheng Yu Ren-xian Yuan Qi-Bing Yuan Hai-Qun Zhang Miao Zhang Wen-Zhi Zhang Li-Ying Zhao Wei-Min zhou Shou-xian Fang Xi-Dong Sun Zhen-Tang Zhao Shanghai Institute of Applied Physics Chinese Academy of SciencesShanghai 201800China Shanghai Advanced Research Institute Chinese Academy of SciencesShanghai 201204China APACTRON Particle Equipment Co. Ltd.Shanghai 201815China The Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China

Because of its excellent dose distribution,proton therapy is becoming increasingly popular in the medical application of cancer treatment.A synchrotron-based proton therapy facility was designed and constructed in *** synchrotron,beam delivery system,and other technical systems were commissioned and reached their expected *** a clinical trial of 47 patients was finished,the proton therapy facility obtained a registration certificate from the National Medical Products *** characteristics of the accelerator and treatment systems are described in this article.

关键词： Proton therapy Synchrotron Slow extraction Gantry Beam delivery system

Establishment of an efficient reverse genetic system of Mumps virus S79 from cloned DNA

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World Journal of Pediatrics 2019年第5期15卷 499-505页

作者： Duo zhou Meng-Ying Zhu Yi-Long Wang Xiao-Qiang Hao Dong-Ming zhou Rong-xian Liu Chu-Di Zhang Chu-Fan Qu Zheng-Yan Zhao Zhejiang University School of Medicine HangzhouChina Children's Hospital Zhejiang University School of MedicineHangzhou 310052China Department of Neurology Children's HospitalZhejiang University School of MedicineHangzhou 310052China

Background Mumps is a common type of respiratory infectious disease caused by mumps virus(MuV),and can be effectively prevented by *** this study,a reverse genetic system of MuV that can facilitate the rational design of safer,more efficient mumps vaccine candidates is *** MuV-S79 cDNA clone was assembled into a full-length plasmid by means of the GeneArtTM High-Order Genetic Assembly System,and was rescued via reverse genetic ***-PCR,sequencing,and immunofluorescence assays were used for rMuV-S79 *** replication kinetics and in vivo experimental models were used to evaluate the replication,safety,and immunogenicity of *** A full-length cDNA clone of MuV-S79 in the assembly process was generated by a novel plasmid assemble strategy,and a robust reverse genetic system of MuV-S79 was successfully *** established rMuV-S79 strain could reach a high virus titer in *** average viral titer of rMuV-S79 in the lung tissues was 2.68±0.14 log10PFU/g lung tissue,and rMuV-S79 group did not induce inflammation in the lung tissues in cotton *** antibody titers induced by rMuV-S79 were high,long-lasting and could provide complete protection against MuV wild strain *** We have established a robust reverse genetic system of MuV-S79 which can facilitate the optimization of mumps ***-S79 rescued could reach a high virus titer and the safety was proven in *** could also provide complete protection against MuV wild strain challenge.

关键词： Mumps virus Reverse genetics Plasmid Safety Immunogenicity

Decreased expression of β-nerve growth factor correlated with histological changes in a cryptorchidism rat model

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Chinese Medical Journal 2012年第4期125卷 713-716页

作者： xian Hua xian Yun JIANG Chun-yi NIE Xiao WANG Xu-dong CHENG Hong-xia HE Jiang-hong WANG Yong-jun zhou Yan HUANG Jian-fei Surgical Comprehensive Laboratory Affiliated Hospital of Nantong University Nantong Jiangsu 226001 China Department of Pediatric Surgery Affiliated Hospital of Nantong University Nantong Jiangsu 226001 China Key Laboratory of Neuroregeneration Nantong UniversityNantong Jiangsu 226001 China Department of Pathology Affiliated Hospital of Nantong University Nantong Jiangsu 226001 China Surgical Comprehensive Laboratory Affiliated Hospital of Nantong University Nantong Jiangsu 226001 China Department of Pediatric Surgery Affiliated Hospital of Nantong University Nantong Jiangsu 226001 China Department of Pathology Affiliated Hospital of Nantong University Nantong Jiangsu 226001 China Surgical Comprehensive Laboratory Affiliated Hospital of Nantong University Nantong Jiangsu 226001 China

Background Nerve growth factor （NGF） is well-known for its important role in the development and maintenance of the nervous *** with its neurotrophic role,NGF has been detected in the testis of mouse,rat and human,suggesting an additional non-neurotrophic effect in the male reproductive *** expression of β-NGF in the undescended testes （cryptorchidism） has not been detected at *** aim of this study was to evaluate the expression of β-nerve growth factor mRNA and protein in experimental *** A unilateral mechanical cryptorchidism model in the Sprague-Dawley rat was established and the expression of β-NGF with histologic changes in experimental cryptorchidism were investigated using one step quantitative real-time reverse transcription-polymerase chain reaction,in situ hybridization histochemistry,immunofluorescence and hematoxylin-eosin *** The expression of β-NGF mRNA and protein were both significantly decreased in the development of unmarred testis and cryptorchidism-induced testis,and the decrease of β-NGF in cryptorchidism-induced testis was far greater than that in uninjured *** From this investigation,we confirmed a lower expression of β-NGF in undescended testes than in the development of testis.

关键词： nerve growth factor cryptorchidism rat infancy period sexual maturityperiod

基于连续数值模拟的筒仓卸载过程中颗粒物压强及其速度场分析

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物理学报 2019年第13期68卷 224-232页

作者：周益娴华北电力大学非能动核能安全技术北京市重点实验室

应用基于局部本构理论的连续数值模拟方法,研究出口在底部和侧面的颗粒物在类三维矩形容器内的卸载现象.重点是容器厚度W和出口高度D对颗粒物压强与速度的影响.受力分析和数值模拟结果均表明,距离出口较近区域的颗粒物压强与W及D呈现如... 详细信息

应用基于局部本构理论的连续数值模拟方法,研究出口在底部和侧面的颗粒物在类三维矩形容器内的卸载现象.重点是容器厚度W和出口高度D对颗粒物压强与速度的影响.受力分析和数值模拟结果均表明,距离出口较近区域的颗粒物压强与W及D呈现如下相关性:当D/W足够小时,压强只与D相关;当D/W足够大时,压强只与W相关.且出口在底部和侧面时均有上述结果.模拟结果还显示,当出口在底部时,对于模拟中所有D/W值,出口中心处法向速度只和D相关;当出口在侧面时,颗粒物出口中心处法向速度则与压强变化规律一致.由此可见,出口处的压强并不控制颗粒物的出口法向速度.另外,与出口在侧面相比,出口在底部时,造成流量相关性规律改变的D/W临界值较大,一般实际情况无法满足,因此出口中心处法向速度只与D相关,始终满足Beverloo定律.

关键词：局部本构关系连续数值模拟颗粒物质筒仓卸载