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新型机械轴向变磁通永磁同步电机分析研究

电机与控制学报 2017年第6期21卷 26-33页

作者：刘细平钟清伟谢清华黄跃飞江西理工大学电气工程与自动化学院江西赣州341000 江西理工大学机电工程学院江西赣州341000

为解决传统变磁通永磁电机在基速以上运行可靠性差和调磁困难的问题,提出一种附加机械调磁装置的新型轴向变磁通永磁同步电机。采用有限元法对电机运行于不同转速时的磁场分布进行分析,建立轴向变磁通永磁同步电机三维有限元仿真模型,... 详细信息

为解决传统变磁通永磁电机在基速以上运行可靠性差和调磁困难的问题,提出一种附加机械调磁装置的新型轴向变磁通永磁同步电机。采用有限元法对电机运行于不同转速时的磁场分布进行分析,建立轴向变磁通永磁同步电机三维有限元仿真模型,获得了电机在不同转速下气隙磁密、绕组磁链及空载反电势、电感等电磁特性。分析结果表明:在基速以下时,机械调磁装置不动作,该电机能以大转矩运行;在基速以上时,机械装置相应动作,电机可在宽范围恒功率运行,调磁效果较好。通过制作样机和构建电机系统试验平台,验证了理论分析和设计的有效性。

关键词：机械变磁通永磁同步电机轴向磁通电磁特性有限元分析

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健全作战部队技术保障人才队伍激励机制

西安政治学院学报 2005年第6期18卷 50-51页

作者：席庆伟西安政治学院研究生队陕西西安710068

为激发部队技术保障人才的工作热情,提高其全面素质,需要建立由目标激励、物质激励、职务激励、荣誉激励、知识激励、淘汰激励构成的完善的激励机制。

关键词：作战部队技术保障人才激励机制

采用湿法成形工艺制备聚烯烃碱性电池隔膜的研究

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中国造纸 2017年第9期36卷 17-23页

作者：张丙旭侯庆喜刘苇梁志辉天津市制浆造纸重点实验室天津科技大学造纸学院天津300457

以聚丙烯纤维和聚乙烯/聚丙烯双组分皮芯结构(ES)纤维为原料,采用湿法成形工艺制备匀度高、质量高的碱性电池隔膜。通过调节湿法成形和热压条件改变隔膜的内部结构,采用磺化处理方法使隔膜具有吸碱性,探索湿法成形工艺制备聚烯烃碱性电... 详细信息

以聚丙烯纤维和聚乙烯/聚丙烯双组分皮芯结构(ES)纤维为原料,采用湿法成形工艺制备匀度高、质量高的碱性电池隔膜。通过调节湿法成形和热压条件改变隔膜的内部结构,采用磺化处理方法使隔膜具有吸碱性,探索湿法成形工艺制备聚烯烃碱性电池隔膜的优化工艺。结果表明,隔膜成形的最佳热压压力和热压温度分别为0.5 MPa和135℃,纤维之间形成了多接触点的熔融结合,隔膜手抄片强度上升;聚氧化乙烯(PEO)用量为1.5%、聚乙烯醇(PVA)用量为4%和ES纤维用量为40%时,可以获得匀度和机械强度较好的隔膜;磺化后的隔膜成功接枝上磺酸基,使隔膜具备较强的亲水性。自制碱性电池隔膜的性能均符合行业标准GJB3535(1999)的要求。

关键词：聚丙烯纤维 ES纤维湿法成形隔膜热压磺化

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坦克射击模拟器中实时纹理映射技术

计算机辅助设计与图形学学报 1998年第6期10卷 487-493页

作者：韩小西唐卫清朱竞夫赵碧君装甲兵工程学院外训系中国科学院计算技术研究所CAD开放实验室

模拟训练是现代军事训练的重要且有效的手段，为了提高坦克射击模拟器的视觉真实度，在分析了坦克瞄准镜视场的特点及其变动规律后，建立相应的视景显示数学模型，并根据模型的特殊性，提出一个快速纹理生成算法，该算法在微机平台上可... 详细信息

模拟训练是现代军事训练的重要且有效的手段，为了提高坦克射击模拟器的视觉真实度，在分析了坦克瞄准镜视场的特点及其变动规律后，建立相应的视景显示数学模型，并根据模型的特殊性，提出一个快速纹理生成算法，该算法在微机平台上可以实时生成地面环境，从而能逼真地模拟坦克行进间射击的动态场面．

关键词：纹理映射坦克射击模拟器军事训练器材

Infiltration by monocytes of the central nervous system and its role in multiple sclerosis: reflections on therapeutic strategies

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Neural Regeneration Research 2025年第3期20卷 779-793页

作者： Guangyong Zhang qing Yao Chubing Long Pengcheng Yi Jiali Song Luojia Wu wei Wan xiuqin Rao Yue Lin Gen wei Jun Ying Fuzhou Hua Department of Anesthesiology the Second Affiliated Hospital of Nanchang UniversityNanchangJiangxi ProvinceChina Key Laboratory of Anesthesiology of Jiangxi Province NanchangJiangxi ProvinceChina

Mononuclear macrophage infiltration in the central nervous system is a prominent feature of neuroinflammation. Recent studies on the pathogenesis and progression of multiple sclerosis have highlighted the multiple roles of mononuclear macrophages in the neuroinflammatory process. Monocytes play a significant role in neuroinflammation, and managing neuroinflammation by manipulating peripheral monocytes stands out as an effective strategy for the treatment of multiple sclerosis, leading to improved patient outcomes. This review outlines the steps involved in the entry of myeloid monocytes into the central nervous system that are targets for effective intervention: the activation of bone marrow hematopoiesis, migration of monocytes in the blood, and penetration of the blood–brain barrier by monocytes. Finally, we summarize the different monocyte subpopulations and their effects on the central nervous system based on phenotypic differences. As activated microglia resemble monocyte-derived macrophages, it is important to accurately identify the role of monocyte-derived macrophages in disease. Depending on the roles played by monocyte-derived macrophages at different stages of the disease, several of these processes can be interrupted to limit neuroinflammation and improve patient prognosis. Here, we discuss possible strategies to target monocytes in neurological diseases, focusing on three key aspects of monocyte infiltration into the central nervous system, to provide new ideas for the treatment of neurodegenerative diseases.

关键词： blood–brain barrier macrophages monocytes multiple sclerosis neuroinflammation review therapy

Relationship between longitudinal changes in lipid composition and ischemic stroke among hypertensive patients

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World Journal of Clinical Cases 2025年第4期13卷 18-27页

作者： Cheng-Cheng wei Yu-qing Huang Cheng-Hong Yu Department of Cardiology Tongxiang First People's HospitalTongxiang 314500Zhejiang ProvinceChina Department of Cardiology Guangdong Cardiovascular InstituteGuangzhou 510080Guangdong ProvinceChina

BACKGROUND Dyslipidemia was strongly linked to stroke,however the relationship between dyslipidemia and its components and ischemic stroke remained *** To investigate the link between longitudinal changes in lipid profiles and dyslipidemia and ischemic stroke in a hypertensive *** Between 2013 and 2014,6094 hypertension individuals were included in this,and ischemic stroke cases were documented to the end of *** changes of lipid were stratified into four groups:(1)Normal was transformed into normal group;(2)Abnormal was transformed into normal group;(3)Normal was transformed into abnormal group;and(4)Abnormal was transformed into abnormal *** examine the link between longitudinal changes in dyslipidemia along with its components and the risk of ischemic stroke,we utilized multivariate Cox proportional hazards models with hazard ratio(HR)and 95%*** The average age of the participants was 62.32 years±13.00 years,with 329 women making up 54.0%of the *** the course of a mean follow-up of 4.8 years,143 ischemic strokes *** normal was transformed into normal group was used as a reference,after full adjustments,the HR for dyslipidemia and ischemic stroke among abnormal was transformed into normal group,normal was transformed into abnormal group and abnormal was transformed into abnormal wei CC et *** changed and ischemic stroke WJCC https://*** 2 February 6,2025 Volume 13 Issue 4 group were 1.089(95%CI:0.598-1.982;P=0.779),2.369(95%CI:1.424-3.941;P<0.001)and 1.448(95%CI:1.002-2.298;P=0.047)(P for trend was 0.233),*** In individuals with hypertension,longitudinal shifts from normal to abnormal in dyslipidemia-particularly in total and low-density lipoprotein cholesterol-were significantly associated with the risk of ischemic stroke.

关键词： Longitudinal change Hypertension Dyslipidemia Lipid profile Ischemic stroke

Tranylcypromine upregulates Sestrin 2 expression to ameliorate NLRP3-related noise-induced hearing loss

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Neural Regeneration Research 2025年第5期20卷 1483-1494页

作者： xihang Chen Zhifeng Chen Menghua Li weiwei Guo Shuolong Yuan Liangwei Xu Chang Lin xi Shi wei Chen Shiming Yang Senior Department of Otolaryngology Head and Neck Surgery Chinese PLA General HospitalChinese PLA Medical SchoolBeijingChina State Key Laboratory of Hearing and Balance Science BeijingChina National Clinical Research Center for Otolaryngologic Diseases BeijingChina Key Laboratory of Hearing Science Ministry of EducationBeijingChina Beijing Key Laboratory of Hearing Impairment Prevention and Treatment BeijingChina Department of Otorhinolaryngology Head and Neck Surgery The First Affiliated Hospital of Fujian Medical UniversityFuzhouFujian ProvinceChina Department of Otolaryngology Head and Neck Surgery The 940th Hospital of Joint Logistics Support Force of Chinese PLALanzhouGansu ProvinceChina Key Laboratory of Tropical Biological Resources of Ministry of Education School of Pharmaceutical SciencesHainan UniversityHaikouHainan ProvinceChina Academician Workstation of Hainan University School of Pharmaceutical SciencesYazhou BaySanyaHainan ProvinceChina

Noise-induced hearing loss is the primary non-genetic factor contributing to auditory ***,there are currently no effective pharmacological interventions for patients with noise-induced hearing ***,we present evidence suggesting that the lysine-specific demethylase 1 inhibitor–tranylcypromine is an otoprotective agent that could be used to treat noise-induced hearing loss,and elucidate its underlying regulatory *** established a mouse model of permanent threshold shift hearing loss by exposing the mice to white broadband noise at a sound pressure level of 120 d B for 4 *** found that tranylcypromine treatment led to the upregulation of Sestrin2(SESN2)and activation of the autophagy markers light chain 3B and lysosome-associated membrane glycoprotein 1 in the cochleae of mice treated with *** noise exposure group treated with tranylcypromine showed significantly lower average auditory brainstem response hearing thresholds at click,4,8,and 16 k Hz frequencies compared with the noise exposure group treated with *** findings indicate that tranylcypromine treatment resulted in increased SESN2,light chain 3B,and lysosome-associated membrane glycoprotein 1 expression after noise exposure,leading to a reduction in levels of 4-hydroxynonenal and cleaved caspase-3,thereby reducing noise-induced hair cell ***,immunoblot analysis demonstrated that treatment with tranylcypromine upregulated SESN2 expression via the autophagy *** treatment also reduced the production of NOD-like receptor family pyrin domaincontaining 3(NLRP3)*** conclusion,our results showed that tranylcypromine treatment ameliorated cochlear inflammation by promoting the expression of SESN2,which induced autophagy,thereby restricting NLRP3-related inflammasome signaling,alleviating cochlear hair cell loss,and protecting hearing *** findings suggest that inhibiting lysine-specific demethylase 1 is a

关键词： 4-hydroxynonenal apoptosis autophagy cleaved caspase-3 inflammation NOD-like receptor family pyrin domain-containing 3(NLRP3) noise-induced hearing loss oxidative stress Sestrin2 tranylcypromine

MicroRNA-21和microRNA-664减轻肾缺血再灌注损伤的研究

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中国现代医学杂志 2017年第2期27卷 19-25页

作者：胡红林习小庆唐伟伟叶真逢黄雅为林双泉项明峰南昌大学第二附属医院泌尿外科江西南昌330006

目的探讨microRNA-21和microRNA-664对肾缺血再灌注损伤(IRI)的影响。方法应用agomir-21和agomir-664预处理BALB/c小鼠,采用双侧肾蒂阻断法复制小鼠肾IRI模型,小鼠肾缺血再灌注后24 h,采用实时荧光定量聚合酶链反应(q RT-PCR)法和Wester... 详细信息

目的探讨microRNA-21和microRNA-664对肾缺血再灌注损伤(IRI)的影响。方法应用agomir-21和agomir-664预处理BALB/c小鼠,采用双侧肾蒂阻断法复制小鼠肾IRI模型,小鼠肾缺血再灌注后24 h,采用实时荧光定量聚合酶链反应(q RT-PCR)法和Western blot检测缺血后肾组织中microRNA-21和microRNA-664及其靶基因、靶蛋白的表达,观察肾脏病理组织学的变化。结果 agomir-21和agomir-664预处理BALB/c小鼠经肾IRI后,肾脏损伤减轻,表现为肾小管上皮细胞坏死降低,进一步检测发现microRNA-21和microRNA-664的靶基因PTEN、PDCD4和MAPK表达降低,靶蛋白Caspase-3和ERK1/2表达受抑制。结论 Micro RNA-21和microRNA-664可以通过调控其靶基因、靶蛋白的表达,从而减轻肾缺血再灌注损伤。

关键词：肾缺血再灌注损伤 microRNA-21 micmRNA-664

Laser direct writing of flexible multifunctional airflow sensors on the Kevlar fabric

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Nano Research 2025年第1期18卷 443-454页

作者： wei Wang Zi-qing Chen Yong-Qi Li Yu-Long Wang Mei-Chen Liu Yun-Bo Ruan Yang Zhang Shu-Juan Liu Qiang Zhao College of Electronic and Optical Engineering and College of Flexible Electronics(Future Technology) Nanjing University of Posts and TelecommunicationsNanjing 210023China State Key Laboratory of Organic Electronics and Information Displays and Jiangsu Key Laboratory for Biosensors Institute of Advanced Materials(IAM)Nanjing University of Posts and TelecommunicationsNanjing 210023China Zhe Jiang Topsun Logistic Control CO. LTD.Yuhuan 317600China Department of Rehabilitation Medicine School of Acupuncture-Moxibustion and Tuina and School of Health Preservation and RehabilitationNanjing University of Chinese MedicineNanjing 210023China

The growing interest in flexible devices has emerged as a global trend due to their advantages in flexibility,lightweight structure,and wearability,addressing the limitations of traditional *** wearable airflow sensors have been previously reported,the development of flexible fabric-based airflow sensors capable of functioning in environments with open flames—critical for fire rescue operations—has yet to be explored,largely due to the poor fire resistance of conventional *** this work,we first present a flexible,wearable,and multifunctional airflow sensor with excellent fire-resistant properties,fabricated through a simple direct laser writing *** sensor maintains airflow detection capabilities even in the presence of open ***,the fabrication of fabric-based sensors involves complex procedures such as carbon materials doping or vapor-phase deposition,leading to lengthy preparation cycles and high ***,fabric-based devices are inherently prone to *** address these challenges,we introduce twice-vertical laser-induced graphene(TVLIG)as a sensitive and reliable component for fire-resistant airflow *** resulting TVLIG/Kevlar fabric can be integrated into various garments,particularly protective suits,to form sensitive and fire-resistant airflow sensors capable of detecting airflow velocity and direction in both two-dimensional(2D)and three-dimensional(3D)spaces during fire ***,the TVLIG patterns can be expanded to multifunctional platforms,such as glucose detection for injured individuals,offering further applications in rescue *** functional expansion reduces the burden on rescue personnel and streamlines device *** its outstanding sensing capabilities,fire resistance,and expandability,the developed flexible airflow sensor shows great potential for various real-world rescue scenarios,promising advancements in wearable sensing technology for rescue enginee

关键词： flexible airflow sensor direct laser writing twice-vertical laser-induced graphene fire accident rescue Kevlar fabric