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CORONARY ANGIOGRAPHY WITH DUAL SOURCE COMPUTED TOMOGRAPHY:INITIAL EXPERIENCE

Chinese Medical Sciences Journal 2007年第4期22卷 205-210页

作者： Zhu-hua Zhang Zheng-yu Jin Shu-yang Zhang Song-bai lin Dong-jing li ling-yan Kong Yi-ning Wang Lan Song Yun Wang Wen-min Zhao Wen-bin Mou li-ren Zhang Wen-ling Zhu Qi Miao Qi Fang Department of Radiology Peking Union Medical College Hospital Chinese Academy of Medical Sciences ＆ Peking Union Medical College Beijing 100730 Department of Cardiology Peking Union Medical College Hospital Chinese Academy of Medical Sciences ＆ Peking Union Medical College Beijing 100730 Special Medical Care Center Peking Union Medical College Hospital Chinese Academy of Medical Sciences ＆ Peking Union Medical College Beijing 100730 Department of Cardiac Surgery Peking Union Medical College Hospital Chinese Academy of Medical Sciences ＆ Peking Union Medical College Beijing 100730

Objective To explore the scan technique and image quality of coronary angiography with dual source computed tomography(CT) without oral metoprolol *** Plain and enhanced dual source CT coronary angiography without oral metoprolol preparation was prospectively performed in 600 *** scoring with plain scan images as well as multi-planar reconstruction(MPR),maximum intensity projection(MIP),and volume rendering technique(VRT) reconstruction with enhanced scan images were performed in all *** scan technique and post-reconstruction experience was *** image quality was classified as 1 to 4 points,and coronary segments classified according to the American Heart Association standards were *** The average calcium score of the 600 cases was 213.6±298.7(0-3 216.5).The average heart rate of the enhanced scan was 82.1±16.2(47-139) *** post-reconstruction methods with which coronary segments could be shown as best as possible consisted of single phase reconstruction method,two or more phases supplemented method,and electrocardiogram editing *** 8 457 coronary segments were evaluated,among which 97.2% were evaluated as point 1,1.7% point 2,0.5% point 3,and 0.6% point *** coronary segments in 261 cases were completely normal,while 360 segments were diagnosed with <50% stenosis and 625 segments with ≥50% *** Excellent coronary artery image can be obtained with dual source CT in patients with any heart rate without oral metoprolol *** rate is not a major source of the artifact,coronary segments can be well shown with single or multiple-phase reconstruction method.

关键词： computed tomography coronary angiography coronary heart disease

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A Retrospective Survival Analysis of Anatomic and Prognostic Stage Group Based on the American Joint Committee on Cancer 8th Edition Cancer Staging Manual in Luminal B Human Epidermal Growth Factor Receptor 2-negative Breast Cancer

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Chinese Medical Journal 2017年第16期130卷 1945-1952页

作者： ling Xu Jiang-Hong li jing-Ming Ye Xue-ning Duan Yuan-Jia Cheng ling Xin Qian liu bin Zhou Yin-Hua liu Breast Disease Center Peking University First Hospital Beijing 100034 China Department of General Surgery The Third Hospital of Shijiazhuang Shijiazhuang Hebei 050011 China

Background： Current understanding of tumor biology suggests that breast cancer is a group of diseases with different intrinsic molecular subtypes. Anatomic staging system alone is insufficient to provide future outcome information. The American Joint Committee on Cancer （AJCC） expert panel updated the 8th edition of the staging manual with prognostic stage groups by incorporating biomarkers into the anatomic stage groups. In this study, we retrospectively analyzed the data from our center in China using the anatomic and prognostic staging system based on the AJCC 8th edition staging manual. Methods： We reviewed the data from January 2008 to December 2014 for cases with Luminal B Human Epidermal Growth Factor Receptor 2 （HER2）-negative breast cancer in our center. All cases were restaged using the AJCC 8th edition anatomic and prognostic staging system. The Kaplan-Meier method and log-rank test were used to compare the survival differences between different subgroups. SPSS software version 19.0 （IBM Corp., Armonk, NY, USA） was used for the statistical analyses. Results： This study consisted of 796 patients with Luminal B HER-negative breast cancer. The 5-year disease-free survival （DFS） of 769 Stage I-III patients was 89.7%, and the 5-year overall survival （OS） of all 796 patients was 91.7%. Both 5-year DFS and 5-year OS were significantly different in the different anatomic and prognostic stage groups, There were 372 cases （46.7%） assigned to a different group. The prognostic Stage II and III patients restaged from anatomic Stage III had significant differences in 5-year DFS （v2 = 11.319; P = 0.001） and 5-year OS （χ2 = 5.225, P = 0.022）. In addition, cases restaged as prognostic Stage I, II, or III from the anatomic Stage II group had statistically significant differences in 5-year DFS （χ2 = 6.510, P = 0.039） but no significant differences in 5-year OS （χ2 = 5.087, P = 0.079）. However, the restaged prognostic Stage I and II cases from anatomic Stage I had no statist

关键词： American Joint Committee on Cancer Biomarker Breast Cancer Cancer Stage Luminal B Human EpidermalGrowth Factor Receptor 2-negative Prognostic Factors

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Study on Evaluation Index of Fabric Heat-moisture Comfort Performance using Grey Theory

Study on Evaluation Index of Fabric Heat-moisture Comfort Pe...

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绿色纺织，健康生活——第三届纺织生物工程及信息学国际会议

作者： Xiao-ning jing, Ya-bin li School of Textiles, Tianjin Polytechnic University, Tianjin, China

This article makes experiments using 9 knitting underwear fabrics made of new regenerated fibers, such as pearl fiber, modal fiber, soybean fiber, bamboo fiber and PLA fiber. Firstly, this study tests the heat- moisture comfort performance with GB 110489 plate warmth retention instrument and GB/T12074-91 water vapor transmission dish, and compares the results with the thermal insulation and moisture vapor resistance values tested with ISO 11092 sweating hot plate. Then make an analysis of the experimental results using grey theory to study the correlation between them in evaluating heat-moisture comfort performance of fabrics. Finally, make out conclusions that thermal insulation makes the largest correlation with the "clo" value, moisture vapor resistance makes the largest correlation with "equivalent water vapor transmission". Accordingly, in evaluating the heat-moisture comfort performance of fabrics, we can take into account of using the "clo" value and "equivalent water vapor transmission" testing with conventional method to substitute the thermal insulation and moisture vapor resistance values from sweating hot plate in order to reduce testing costs.

关键词： regenerated fiber heat- moisture comfort conventional method sweating hot plate instrument grey theory

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参与汶川地震伤员救治与未参与伤员救治外科医务人员的心理状况分析

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中南大学学报（医学版） 2008年第9期33卷 769-775页

作者：宁宁李玲利廖灯彬安晶晶陈忠兰四川大学华西医院骨科成都610041

目的:比较分析汶川地震期间参与震灾伤员救治骨外科医务人员与未参与伤员救治外科医务人员的心理状况,为建立大地震救援援助医务人员的心理问题预防和干预体系提供参考依据。方法:采用方便抽样的方法抽取参与震灾伤员救治的骨外科医务... 详细信息

目的:比较分析汶川地震期间参与震灾伤员救治骨外科医务人员与未参与伤员救治外科医务人员的心理状况,为建立大地震救援援助医务人员的心理问题预防和干预体系提供参考依据。方法:采用方便抽样的方法抽取参与震灾伤员救治的骨外科医务人员与未参与震灾伤员救治外科医务人员作为研究对象进行横断面调查研究。采用症状自评量表(SCL-9 0),征得调查对象同意后由心理咨询师采用统一、规范的指导语指导研究对象完成调查问卷,用SPSS1 6.0软件对数据进行统计处理。结果:地震期间,参与震灾伤员救治与未参与伤员救治外科医务人员在躯体化、强迫、人际关系敏感、抑郁、焦虑、敌对、恐怖、精神病性等8个因子均值统计学结果有统计学差异;两组研究对象的因子阳性项目数也存在统计学差异。结论:地震期间,参与震灾伤员救治的骨外科医务人员存在明显的心理问题,需要进行心理干预。

关键词：医务人员症状自评量表心理健康地震

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基于被动微波遥感和BP神经网络的土壤水分反演研究——以川中丘陵区为例

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西南农业学报 2014年第6期27卷 2478-2484页

作者：徐小逊张萍徐精文黄飞宁黎四川农业大学资源环境学院四川成都611130

以川中丘陵区为研究对象,利用2006-2010年的AMSR-E数据和土壤水分观测数据,进行优选输入因子筛选,构建了一个4因子的BP神经网络模型,并对该模型的模拟精度进行了分析与验证。结果表明:基于AMSR-E数据所构建的BP神经网络土壤水分反演模... 详细信息

以川中丘陵区为研究对象,利用2006-2010年的AMSR-E数据和土壤水分观测数据,进行优选输入因子筛选,构建了一个4因子的BP神经网络模型,并对该模型的模拟精度进行了分析与验证。结果表明:基于AMSR-E数据所构建的BP神经网络土壤水分反演模型的模拟值(r=0.4968**)较单独的AMSR-E土壤水分产品(r=-0.0115**)与实测值的相关性更高。反演结果验证表明BP神经网络模型更能反映实际情况,用其进行川中丘陵区的土壤水分反演是可行的。

关键词：被动微波遥感 BP神经网络土壤水分反演川中丘陵区

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单源前体合成水溶性的CdS和ZnS纳米晶

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无机化学学报 2007年第5期23卷 928-932页

作者：经斌黄怡陈佑宁杨瑞丽咸阳师范学院化学系咸阳712000

量子点（Quantum Dots）一般指半径小于或接近玻尔激子半径的半导体纳米晶颗粒。和有机染料分子相比．无机半导体纳米晶的带隙宽度可通过简单地改变其物理尺寸而得到调节，从而能够实现纳米晶的不同能量发射．而且可产生色纯度较高的发... 详细信息

量子点（Quantum Dots）一般指半径小于或接近玻尔激子半径的半导体纳米晶颗粒。和有机染料分子相比．无机半导体纳米晶的带隙宽度可通过简单地改变其物理尺寸而得到调节，从而能够实现纳米晶的不同能量发射．而且可产生色纯度较高的发射光．它们在发光二极管和生物荧光标记等应用方面是一类非常有前途的材料。

关键词：纳米晶量子点 CdS 单源前体

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Cerebellar fastigial nuclear inputs impinge on feeding-related neurons in ventromedial hypotha-lamic nucleus in rats

Cerebellar fastigial nuclear inputs impinge on feeding-relat...

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中国生理学会第24届全国会员代表大会暨生理学学术大会

作者： bin li Qian-Xing Zhuang He-Ren Gao jing-ning Zhu Jian-Jun Wang School of life Sciences Nanjing University

The ventromedial hypothalamic nucleus（VMN）has traditionally been implicated in feeding behavior,energy balance,and body weight *** studies have indicated that neurons in the VMN receive various peripheral feeding-related signals,such as the gastric vagal inputs,blood glucose,and ghrelin,a peptide primarily produced in the stomach and stimulating both feeding and growth hormone ***,the cerebellum,a classic subcortical somatic motor center,participates in regulation of nonsomatic visceral activities including food intake via the direct cerebellohypothalamic ***,by using anterograde axonal tract tracings and extracellular recordings in vivo in rats,the present study was designed to investigate whether the outputs of cerebellar fastigial nucleus（FN）could reach and converge with the feeding-related gastric vagal,glycemia and ghrelin signals onto single VMN ***,anterograde tracers,biotinylated dextran amine（BDA）and Phaseolus vulgaris-leucoagglutinin（PHA-L）,were injected into the cerebellar FN and nucleus tractus solitarius（NTS）,a critical relay nucleus in the pathway transmitting information from the gastric vagal nerves to VMN,*** results show that both the projections of cerebellar FN and NTS reach and converge onto single glucose-sensitive neurons in the ***,of the 179 VMN neurons recorded,97（97/179,54.2%）responded to the cerebellar FN stimulation,in which 85（85/97,87.6%）were also responsive to gastric vagal stimulation,suggesting a convergence of cerebellar FN and gastric vagal inputs on the VMN ***,a summation of responses was observed（n=7）when the cerebellar FN and gastric vagal nerve were simultaneously *** the 22 VMN neurons responsive to both the cerebellar FN and gastric vagal stimulations,16（72.7%）cells also responded to the systemic administrations of glucose and *** results demonstrated that the somatic information forwarded by the cerebel

关键词： cerebellar fastigial nucleus ventromedial hypothalamic nucleus ghrelin somatic-visceral integration

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The Chromosome-Based Rubber Tree Genome Provides New Insights into Spurge Genome Evolution and Rubber Biosynthesis

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Molecular Plant 2020年第2期13卷 336-350页

作者： Jin liu Cong Shi Cheng-Cheng Shi Wei li Qun-Jie Zhang Yun Zhang Kui li Hui-Fang Lu Chao Shi Si-Tao Zhu Zai-Yun Xiao Hong Nan Yao Yue xun-Ge Zhu Yu Wu Xiao-ning Hong Guang-Yi Fan Yan Tong Dan Zhang Chang-li Mao Yun-Long liu Shi-Jie Hao Wei-Qing liu Mei-Qi Lv Hai-bin Zhang Yuan liu Ge-Ran Hu-tang Jin-Peng Wang Jia-Hao Wang Ying-Huai Sun Shu-Bang Ni Wen-bin Chen Xing-Cai Zhang Yuan-Nian Jiao Evan E.Eichler Guo-Hua li Xin liu li-Zhi Gao Yunnan Institute of Tropical Crops Jinghong 666100China Plant Germplasm and Genomics Center Germplasm Bank of Wild Species in Southwestern ChinaKunming Institute of BotanyChinese Academy of SciencesKunming 650204China University of Chinese Academy of Sciences Beijing 100049China BGI-Qingdao Qingdao 266555China lnstitution of Genomics and Bioinformatics South China Agricultural UniversityGuangzhou 510642China Asia-Pacific Tropical Forestry Germplasm Institution Southwest China Forestry UniversityKunming 650224China School of life Sciences Nanjing UniversityNanjing 210023China Novogene Bioinformatics Institute Beijing 100083China BGI-Shenzhen Shenzhen 518083China State key Laboratory of Systematic and Evolutionary Botany Institute of BotanyChinese Academy of SciencesBeijing 100093China John A.Paulson School of Engineering and Applied Sciences Harvard UniversityCambridgeMA 02138USA Howard Hughes Medical Institute University of WashingtonSeattleWA 98195USA

The rubber tree,Hevea brasiliensis,produces natural rubber that serves as an essential industrial raw ***,we present a high-quality reference genome for a rubber tree cultivar GT1 using single-molecule real-time sequencing(SMRT)and Hi-C technologies to anchor the～1.47-Gb genome assembly into 18 *** chromosome-based genome analysis enabled us to establish a model of spurge chromosome evolution,since the common paleopolyploid event occurred before the split of Hevea and *** show recent and rapid bursts of the three Hevea-specific LTR-retrotransposon families during the last 10 million years,leading to the massive expansion by～65.88%(～970 Mbp)of the whole rubber tree genome since the divergence from *** identify large-scale expansion of genes associated with whole rubber biosynthesis processes,such as basal metabolic processes,ethylene biosynthesis,and the activation of polysaccharide and glycoprotein lectin,which are important properties for latex production.A map of genomic variation between the cultivated and wild rubber trees was obtained,which contains～15.7 million high-quality single-nucleotide *** identified hundreds of candidate domestication genes with drastically lowered genomic diversity in the cultivated but not wild rubber trees despite a relatively short domestication history of rubber tree,some of which are involved in rubber *** genome assembly represents key resources for future rubber tree research and breeding,providing novel targets for improving plant biotic and abiotic tolerance and rubber production.

关键词： rubber tree rubber biosynthesis chromosome evolution whole-genome duplication domestication

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Traditional Chinese Medicine guidelines for coronavirus disease 2019

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Journal of Traditional Chinese Medicine 2020年第6期40卷 891-896页

作者： liang ning Ma Yanfang Wang jingya li Huizhen Wang Xiaohui Jiao liwen liu bin Ma Yan Zhao Chen Luo Xufei Zhao Siya Lu Meng Cao Jin Hu Wenpin Zhang Hairong liu Guoxiu Lu Cheng liu Mengyu li li Han Xuejie liu Yuqi Wang liying Zhao Xueyao Wei Dongfeng Bai jing Sun Mingyu Yang Yong Wu Xiaodan Chen Yaolong Shi Nannan Wang Yanping Wang Yongyan Institute of Basic Research in Clinical Medicine China Academy of Chinese Medical SciencesBeijing 100700China Evidence-Based Medicine Center School of Basic Medical SciencesLanzhou UniversityLanzhou 730000China School of Public Health Lanzhou UniversityLanzhou 730000China Beijing University of Chinese Medicine Beijing 100029China Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine Shanghai 201203China Chinese GRADE Center Lanzhou 730000China Lanzhou University an Affiliate of the Cochrane China NetworkLanzhou 730000China key Laboratory of Evidence Based Medicine and Knowledge Translation of Gansu Province Lanzhou UniversityLanzhou 730000China

OBJECTIVE:To summarize the evidence from Traditional Chinese Medicine(TCM)practice in the treatment of coronavirus disease 2019(COVID-19)and provide timely clinical practice ***:The guidelines were developed in accordance with the World Health Organization rapid guideline *** evidence on TCM for COVID-19 from published guidelines,direct and indirect published clinical evidence,first hand clinical data,and expert experience and consensus were *** grading of recommendations assessment,development and evaluation(GRADE)method was used to grade the evidence and make the ***:Based on the available evidence,the guidelines recommended 17 Chinese medicines for COVID-19:2 Chinese herbal granules,7 Chinese patent medicines,and 8 Chinese herbal ***:As the literature search was conducted on March,any subsequent versions of these guidelines require an up-to-date literature *** hope that the evidence summary in these guidelines will be helpful in global efforts to address COVID-19.

关键词： COVID-19 Medicine Chinese traditional Practice guideline

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Direct Involvement of Orexin in the Vestibular Motor Control and Motion Sickness

Direct Involvement of Orexin in the Vestibular Motor Control...

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中国生理学会张锡钧基金会第十三届全国青年优秀生理学学术论文交流及评奖会议、中国生理学会第十一届全国青年生理学工作者学术会议

作者：张潇洋 bin li Shu-liang Cao Qian-Xing Zhuang jing-ning Zhu Jian-JunWang 南京大学生命科学学院 State key Laboratory of Pharmaceutical Biotechnology and Department of Biological Science and Technology School of Life SciencesNanjing University

The deficiency of orexin,a neuropeptide restrictedly synthetized in the hypothalamic,may result in *** the function of the central orexinergicsystem in sleep regulation has been well studied,the role of orexin in motor control is largely *** vestibular nucleus(MVN)is the most important subnucleus in the vestibularnuclear complex in brainstem,which

关键词： Direct Involvement of Orexin in the Vestibular Motor Control and Motion Sickness orexin

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