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Dynamics of loose granular flow and its subsequent deposition in a narrow mountainous river

Journal of Mountain Science 2019年第6期16卷 1367-1380页

作者： LEI Ming xu ze-xing ZHAO Tao WANG Xie-kang State Key Laboratory of Hydraulics and Mountain River Engineering Sichuan University

A large amount of loose debris materials were deposited on the slope of mountainous areas after the 2008 Ms 8.0 Wenchuan earthquake. During and after the earthquake, these loose debris deposits collapsed and slide into valleys or rivers, changing river sediment supply condition and channel morphology. To investigate the mechanisms of granular flow and deposition, the dynamics of slope failure and sediment transportation in typical mountainous rivers of different intersection angles were analyzed with a coupling model of Computational Fluid Dynamics and Discrete Element Method(CFD-DEM). The numerical results show that the change of intersection angle between the granular flow flume and the river channel can affect the deposit geometry and the fluid flow field significantly. As the intersection angle increases, the granular velocity perpendicular to the river channel increases, while the granular velocity parallel to the river channel decreases gradually. Compared to the test of dry granular flow, the CFD-DEM coupling tests show much higher granular velocity and larger volume of sediments entrained in the river. Due to the river flow, particles located at the edge of the deposition will move downstream gradually and the main section of sediments deposition moves from the center to the edge of the river channel. As a result, sediment supply in the downstream river will distribute unevenly. Under the erosion of fluid flow, the proportion of fine particles increases, while the proportion of coarse particles decreases gradually in the sediment deposition. The build-up of accumulated sediment mass will cause a significant increase in water level in the river channel, thus creating serious flooding hazard in mountainous rivers.

关键词： Loose debris materials Sediment supply CFD-DEM coupling method Numerical simulations

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Flow variability along a vegetated natural stream under various sediment transport rates

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Journal of Mountain Science 2018年第11期15卷 2347-2364页

作者： WANG Hai-zhou xu ze-xing Yu Hai-ti WANG Xie-kang State Key Laboratory of Hydraulics and Mountain River Engineering Sichuan University

The influence of vegetation and sediment on flow characteristics in open channels cannot be neglected. To study the flow variability under the effects of the instream natural vegetation and sediment supply, experiments were conducted with varied water and sediment supply in a movable bed of a river prototype. The instantaneous threedimensional velocities near two types of vegetation patches(the shrub and the weed) and along the centerline of the main channel with vegetation belts were measured using a 3-D side-looking acoustic Doppler velocimetry. The experimental results show that both the instream vegetation and sediment supply strongly affect the flow and turbulence characteristics. In the case of vegetation patches, both the shrub and weed have a considerable influence on the distribution of the streamwise velocity and turbulence intensity of their surrounding water. The streamwise velocity distribution followed as J-shape and linear shape around the weed and shrub under different experimental conditions. The turbulence intensity was large at the top of the weed and shrub;the shrub had its greatest influence on the downstream water flow. In the case of vegetation belts,the streamwise velocity along the centerline of the main channel exhibited an S-shape, J-shape and linear shape at different locations under varied water,vegetation structures and riverbed *** turbulence intensity along the centerline of the main channel ranged from 0.0 to 0.1. The upstream turbulence intensity was affected considerably by a sediment supply, while the downstream turbulence intensity changed with the varied vegetation characteristics and riverbed topography. The second flow coefficient M-value increased longitudinally and was almost positive along the centerline of the main channel, implying that the rotational direction of the secondary current cell was clockwise.

关键词： Natural vegetation Sediment supply Velocity profile Turbulence intensity Secondary flow Movable bed

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硒对玉米种子吸胀期间生理特性和种子发芽能力的影响

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甘肃农业大学学报 2017年第1期52卷 63-67,73页

作者：许兴泽赵桂琴杜锦甘肃农业大学草业学院草业生态系统教育部重点实验室中-美草地畜牧业可持续发展研究中心甘肃兰州730070 天津农学院农学与资源环境学院天津300384

【目的】为了探讨硒引发对玉米种子生理生化特性及发芽的影响.【方法】以‘联丰20’和‘郑单958’两个玉米品种为材料,种子经75μmol/L硒酸钠引发48h,在5℃下低温吸胀不同时间(0、12、24、36和48h),测定玉米种子吸胀中的发芽及生理指标... 详细信息

【目的】为了探讨硒引发对玉米种子生理生化特性及发芽的影响.【方法】以‘联丰20’和‘郑单958’两个玉米品种为材料,种子经75μmol/L硒酸钠引发48h,在5℃下低温吸胀不同时间(0、12、24、36和48h),测定玉米种子吸胀中的发芽及生理指标.【结果】硒引发处理玉米种子,不仅能提高低温胁迫期间种子内过氧化物酶(POD)活性,增加了可溶性糖(WSC)、脯氨酸(Pro)和种子浸出液的核苷酸含量,同时也显著提高了发芽率、缩短了平均发芽时间.低温吸胀48h后,与对照相比,75μmol/L硒酸钠引发处理分别使‘联丰20’和‘郑单958’种子的平均发芽率提高了28%和14%,平均发芽时间缩短了7.68h和5.76h.【结论】75μmol/L硒酸钠引发处理可以提高玉米种子吸胀期间各项生理特性,同时也增强了低温胁迫下种子的发芽能力.

关键词：硒玉米种子低温胁迫吸胀发芽

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A low redox potential and long life organic anode material for sodium-ion batteries

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Journal of Energy Chemistry 2025年第1期100卷 557-564页

作者： Zhi Li Yang Wei Kang Zhou Xin Huang xing Zhou Jie xu Taoyi Kong Junwei Lucas Bao Xiaoli Dong Yonggang Wang Department of Chemistry and Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials Institute of New Energy Collaborative Innovation Center of Chemistry for Energy Materials (iChEM) Fudan University Department of Chemistry Boston College School of Materials Science and Engineering Anhui University of Technology

Sodium-ion batteries （SIBs） with organic electrodes are an emerging research direction due to the sustainability of organic materials based on elements like C,H,O,and sodium ***,organic electrode materials for SIBs are mainly used as cathodes because of their relatively high redox potentials（>1 V）.Organic electrodes with low redox potential that can be used as anode are ***,a novel organic anode material （tetrasodium 1,4,5,8-naphthalenetetracarboxylate,Na4TDC） has been developed with low redox potential （<0.7 V） and excellent cyclic *** three-sodium storage mechanism was demonstrated with various in-situ/ex-situ spectroscopy and theoretical calculations,showing a high capacity of 208 mAh/g and an average decay rate of merely 0.022%per ***,the Na4TDC-hard carbon composite can further acquire improved capacity and cycling stability for 1200 cycles even with a high mass loading of up to 20 mg *** pairing with a thick Na3V2（PO4）3cathode (20.6 mg cm-2),the as-fabricated full cell exhibited high operating voltage （2.8 V）,excellent rate performance and cycling stability with a high capacity retention of 88.7% after 200 cycles,well highlighting the Na4TDC anode material for SIBs.

关键词： Organic anode material Low redox potential Composite anode Sodium-ion batteries

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对贝雷钢便桥评标法的思考

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价值工程 2016年第19期35卷 3-5页

作者：徐泽星扶达鸿西安交通大学经济与金融学院西安710061 国网浙江省电力公司杭州310006

贝雷钢便桥采购招标主要采用最低评标价法、综合评估法、合理低价法,而这三种评标法的实际操作结果经常是以最低价中标。最低评标价法的发展经历了招投标双方满意度变化的三个阶段,现已不适应社会可持续发展的需要。为了节省总经费,宜... 详细信息

贝雷钢便桥采购招标主要采用最低评标价法、综合评估法、合理低价法,而这三种评标法的实际操作结果经常是以最低价中标。最低评标价法的发展经历了招投标双方满意度变化的三个阶段,现已不适应社会可持续发展的需要。为了节省总经费,宜采用价值工程评标法,由关注价格转向关注价值,由关注经济性转向关注企业社会责任,促进贝雷桥行业的良性循环,提高中国制造质量。

关键词：贝雷钢便桥评标方法价值工程用户满意度全寿命费用

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气压弹道碎石和等离子电切治疗前列腺增生并膀胱结石

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中国内镜杂志 2006年第9期12卷 966-967,971页

作者：徐兴泽李立宇王周清马贵斌云南曲靖市第二人民医院泌尿外科云南曲靖650032

目的探讨前列腺增生并膀胱结石的有效治疗方法。方法采用经尿道膀胱镜下气压弹道碎石和等离子体双极电切治疗20例BPH并膀胱结石。结果手术时间60～180min,术后3～5d拔管,排尿通畅,无TURS、大出血、膀胱穿孔等并发症。结论膀胱镜下气压... 详细信息

目的探讨前列腺增生并膀胱结石的有效治疗方法。方法采用经尿道膀胱镜下气压弹道碎石和等离子体双极电切治疗20例BPH并膀胱结石。结果手术时间60～180min,术后3～5d拔管,排尿通畅,无TURS、大出血、膀胱穿孔等并发症。结论膀胱镜下气压弹道碎石和等离子体双极电切是治疗前列腺增生并膀胱结石的一种安全、有效的治疗方法。

关键词：前列腺增生膀胱结石等离子体双极电切弹道碎石

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Resting-state brain network remodeling after different nerve reconstruction surgeries:a functional magnetic resonance imaging study in brachial plexus injury rats

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Neural Regeneration Research 2025年第5期20卷 1495-1504页

作者： Yunting Xiang Xiangxin xing xuyun Hua Yuwen Zhang Xin xue Jiajia Wu Mouxiong Zheng He Wang Jianguang xu School of Rehabilitation Science Shanghai University of Traditional Chinese MedicineShanghaiChina Engineering Research Center of Traditional Chinese Medicine Intelligent Rehabilitation Ministry of EducationShanghaiChina Department of Rehabilitation Medicine Yueyang Hospital of Integrated Traditional Chinese and Western MedicineShanghai University of Traditional Chinese MedicineShanghaiChina Department of Traumatology and Orthopedics Yueyang Hospital of Integrated Traditional Chinese and Western MedicineShanghai University of Traditional Chinese MedicineShanghaiChina Institute of Science and Technology for Brain-Inspired Intelligence Fudan UniversityShanghaiChina Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence(Fudan University) Ministry of EducationShanghaiChina Human Phenome Institute Fudan UniversityShanghaiChina

Distinct brain remodeling has been found after different nerve reconstruction strategies,including motor representation of the affected ***,differences among reconstruction strategies at the brain network level have not been *** study aimed to explore intranetwork changes related to altered peripheral neural pathways after different nerve reconstruction surgeries,including nerve repair,endto-end nerve transfer,and end-to-side nerve ***–Dawley rats underwent complete left brachial plexus transection and were divided into four equal groups of eight:no nerve repair,grafted nerve repair,phrenic nerve end-to-end transfer,and end-to-side transfer with a graft sutured to the anterior upper ***-state brain functional magnetic resonance imaging was obtained 7 months after *** independent component analysis algorithm was utilized to identify group-level network components of interest and extract resting-state functional connectivity values of each voxel within the *** in intra-network resting-state functional connectivity were compared among the *** muscle reinnervation was assessed by behavioral observation(elbow flexion)and *** results showed that alterations in the sensorimotor and interoception networks were mostly related to changes in the peripheral neural *** repair was related to enhanced connectivity within the sensorimotor network,while end-to-side nerve transfer might be more beneficial for restoring control over the affected limb by the original motor *** thalamic-cortical pathway was enhanced within the interoception network after nerve repair and end-to-end nerve *** areas related to cognition and emotion were enhanced after end-to-side nerve *** study revealed important brain networks related to different nerve *** networks may be potential targets for enhancing motor recovery.

关键词： brain functional networks end-to-end nerve transfer end-to-side nerve transfer independent component analysis nerve repair peripheral plexus injury resting-state functional connectivity

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Small extracellular vesicles derived from human induced pluripotent stem cell-differentiated neural progenitor cells mitigate retinal ganglion cell degeneration in a mouse model of optic nerve injury

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Neural Regeneration Research 2025年第2期20卷 587-597页

作者： Tong Li Hui-Min xing Hai-Dong Qian Qiao Gao Sheng-Lan xu Hua Ma Zai-Long Chi State Key Laboratory of Ophthalmology Optometry and Visual ScienceEye HospitalWenzhou Medical UniversityWenzhouZhejiang ProvinceChina National Clinical Research Center for Ocular Diseases Eye HospitalWenzhou Medical UniversityWenzhouZhejiang ProvinceChina

Several studies have found that transplantation of neural progenitor cells(NPCs)promotes the survival of injured ***,a poor integration rate and high risk of tumorigenicity after cell transplantation limits their clinical *** extracellular vesicles(sEVs)contain bioactive molecules for neuronal protection and *** studies have shown that stem/progenitor cell-derived sEVs can promote neuronal survival and recovery of neurological function in neurodegenerative eye diseases and other eye *** this study,we intravitreally transplanted sEVs derived from human induced pluripotent stem cells(hiPSCs)and hiPSCs-differentiated NPCs(hiPSC-NPC)in a mouse model of optic nerve *** results show that these intravitreally injected sEVs were ingested by retinal cells,especially those localized in the ganglion cell *** with hiPSC-NPC-derived sEVs mitigated optic nerve crush-induced retinal ganglion cell degeneration,and regulated the retinal microenvironment by inhibiting excessive activation of *** analysis further revealed that hiPSC-NPC derived sEVs transported neuroprotective and anti-inflammatory miRNA cargos to target cells,which had protective effects on RGCs after optic nerve *** findings suggest that sEVs derived from hiPSC-NPC are a promising cell-free therapeutic strategy for optic neuropathy.

关键词： exosome miRNA neural progenitor cell neurodegeneration neuroinflammation neuroprotection optic nerve crush optic neuropathy retinal ganglion cell small extracellular vesicles

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Insights into spinal muscular atrophy from molecular biomarkers

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Neural Regeneration Research 2025年第7期20卷 1849-1863页

作者： Xiaodong xing Xinzhu Liu Xiandeng Li Mi Li Xian Wu Xiaohui Huang Ajing xu Yan Liu Jian Zhang Department of Clinical Pharmacy Xinhua HospitalShanghai Jiao Tong University School of MedicineShanghaiChina College of Pharmacy Chongqing Medical UniversityChongqingChina

Spinal muscular atrophy is a devastating motor neuron disease characterized by severe cases of fatal muscle *** is one of the most common genetic causes of mortality among infants aged less than 2 *** research is currently receiving more attention,and new candidate biomarkers are constantly being *** review initially discusses the evaluation methods commonly used in clinical practice while briefly outlining their respective pros and *** also describe recent advancements in research and the clinical significance of molecular biomarkers for spinal muscular atrophy,which are classified as either specific or non-specific *** review provides new insights into the pathogenesis of spinal muscular atrophy,the mechanism of biomarkers in response to drug-modified therapies,the selection of biomarker candidates,and would promote the development of future ***,the successful utilization of biomarkers may facilitate the implementation of gene-targeting treatments for patients with spinal muscular atrophy.

关键词： biomarkers disease progression gene-targeting therapy neurofilaments Nusinersen spinal muscular atrophy(SMA) survival motor neuron therapeutic evaluation treatment outcomes

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Recent Advances in Fibrous Materials for Hydroelectricity Generation

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Nano-Micro Letters 2025年第2期17卷 109-133页

作者： Can Ge Duo xu Xiao Feng xing Yang Zheheng Song Yuhang Song Jingyu Chen Yingcun Liu Chong Gao Yong Du Zhe Sun Weilin xu Jian Fang College of Textile and Clothing Engineering Soochow UniversitySuzhou 215123People’s Republic of China National Engineering Laboratory for Modern Silk Soochow UniversitySuzhou 215123People’s Republic of China State Key Laboratory of New Textile Materials and Advanced Processing Technologies Wuhan Textile UniversityWuhan 430200People’s Republic of China Institute of Functional Nano&Soft Materials(FUNSOM) Soochow UniversitySuzhou 215123People’s Republic of China Department of Electrical and Computer Engineering University of MassachusettsAmherstMA 01003USA Department of Materials Imperial College LondonSouth Kensington CampusLondon SW72AZUK College of Textile Science and Engineering Zhejiang Sci-Tech UniversityHangzhou 310018People’s Republic of China School of Materials Science and Engineering Shanghai Institute of Technology100 Haiquan RoadShanghai 201418People’s Republic of China

Depleting fossil energy sources and conventional polluting power generation pose a threat to sustainable *** generation from ubiquitous and spontaneous phase transitions between liquid and gaseous water has been considered a promising strategy for mitigating the energy *** materials with unique flexibility,processability,multifunctionality,and practicability have been widely applied for fibrous materials-based hydroelectricity generation(FHG).In this review,the power generation mechanisms,design principles,and electricity enhancement factors of FHG are first ***,the fabrication strategies and characteristics of varied constructions including 1D fiber,1D yarn,2D fabric,2D membrane,3D fibrous framework,and 3D fibrous gel are ***,the advanced functions of FHG during water harvesting,proton dissociation,ion separation,and charge accumulation processes are analyzed in ***,the potential applications including power supply,energy storage,electrical sensor,and information expression are also ***,some existing challenges are considered and prospects for future development are sincerely proposed.

关键词： Hydroelectricity Fibrous material Streaming potential Ion diffusion

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