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Correlation of morphological anisotropy and Lankford value of deep drawing sheets hot-rolled by compact strip production

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International Journal of Minerals,Metallurgy and Materials 2012年第10期19卷 934-938页

作者： Shu-li Li Run Wu Yuan-zheng Wei Zhi-fang Wu xue-jun Zhou yong-fu Zhang Cruang xu School of Material and Metallurgy Wuhan Univorsity of Science and Technology Wuhan 430081 China Wuhan Iron and Steel (Group) Corporation Wuhan 430083 China

Cold-rolled steel sheets in automotive applications require an excellent deep draw ability, which is characterized by the Lankford value （r-value）. In this study, a correlation was identified between r-value and pancake-shaped grain flatness which is indicated as the ratio of grain diameter in the rolling direction （RD） and normal direction （ND） of sheets （dr/dn）. A mathematical model （ r = e^0.345（dn^1/2-dr^1/2）） was developed to calculate r-value by the microstructure of steel sheets hot-rolled by compact strip production （CSP）. It is shown that the r-value is higher, if the microstructure of steel sheet is of pancake-shaped grains elongated in the rolling direction. The calculated r-value is confirmed to fit exactly to the measured one from the large-scale production.

关键词： cold rolling compact strip production (CSP) steel sheets deep drawing anisotropy Lankford values microstructure

Effect of Essential Oil on Patients with Chronic Prostatitis/Chronic Pelvic Pain Syndrome: A Pilot Randomized Controlled Trial

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Chinese Journal of Integrative Medicine 2019年第2期25卷 91-95页

作者： YING jian ZHOU Min-jie CHEN Hai-yong CHEN Lei ZHANG Wei JI Jun YU Chao ZHANG Zhang-jin Department of Urology and Andrology Longhua HospitalShanghai University of Traditional Chinese Medicine Shanghai Qigong Research Institute Shanghai University of Traditional Chinese Medicine Department of Vascular Surgery Shanghai Traditional Chinese Medicine Integrated HospitalShanghai University of Traditional Chinese Medicine School of Chinese Medicine the University of Hong Kong Department of Chinese Medicine the University of Hong Kong-Shenzhen Hospital

Objective: To evaluate the efficacy and safety of essential oil treatment for type Ⅲ chronic prostatitis/chronic pelvic pain syndrome(CP/CPPS). Methods: A randomized controlled trial was conducted from December 2014 to October 2015. Seventy type Ⅲ CP/CPPS patients were assigned to the essential oil group(35 cases) or almond placebo oil control group(35 cases) by a random number table. The oil was smeared by self-massage on the suprapubic and sacral region once a day for 4 weeks. The National Institutes of Health Chronic Prostatitis Syndrome Index(NIH-CPSI) and expressed prostatic secretions(EPS) were examined. The primary outcome was NIH-CPSI pain domain. The secondary outcomes included other NIH-CPSI domains and laboratory examinations of EPS. Adverse events were also observed. Results: Sixty-six subjects completed the full 4-week treatment. There was no significant difference between almond oil control and essential oil groups in terms of the total score of NIH-CPSI, pain, quality of life and urination domain scores of NIH-CPSI and EPS examinations(P>0.05). In the essential oil group, pain between rectum and testicles(perineum) in the domain of pain or discomfort was significantly reduced at week 2 and week 4 compared with almond oil control group(P<0.01). No serious adverse events occurred. Conclusion: The essential oil may reduce the pain or discomfort in the perineum region in patients with CP/CPPS.

关键词： essential oil chronic prostatitis/chronic pelvic pain syndrome randomized controlled trial

Congenital nephrogenic diabetes insipidus arginine vasopressin receptor 2 gene mutation at new site:A case report

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World Journal of Clinical Cases 2022年第36期10卷 13443-13450页

作者： Lu-Lu Yang Yan xu jian-Li Qiu Qian-Yi Zhao Man-Man Li Hui Shi Department of Pediatrics Henan University of Chinese MedicineZhengzhou 450000Henan ProvinceChina Department of Pediatrics The First Affiliated Hospital of Henan University of Chinese MedicineZhengzhou 450000Henan ProvinceChina

BACKGROUND Congenital nephrogenic diabetes insipidus(CNDI)is a rare hereditary *** is associated with mutations in the arginine vasopressin receptor 2(AVPR2)gene and aquaporin 2(AQP2)gene,and approximately 270 different mutation sites have been reported for ***,new mutations and new manifestations are crucial to complement the clinical deficiencies in the diagnosis of this *** report a case of a novel AVPR2 gene mutation locus and a new clinical *** SUMMARY We describe the case of a 48-d-old boy who presented with recurrent fever and diarrhea 5 d after *** tests showed electrolyte disturbances and low urine specific gravity,and imaging tests showed no *** testing revealed a novel X-linked recessive missense mutation,c.283(exon 2)C>T(p.P95S).This mutation results in the substitution of a proline residue with a serine residue in the AVPR2 protein *** diagnosis of CNDI was confirmed based on the AVPR2 gene *** treatment strategy for this patient was divided into two stages,including physical cooling supplemented with appropriate amounts of water in the early stage and oral hydrochlorothiazide(1-2 mg/kg)after a clear *** follow-up of one and a half years,the patient gradually *** AVPR2 gene mutations in new loci and new clinical symptoms help clinicians understand this disease and shorten the diagnosis cycle.

关键词： Congenital nephrogenic diabetes insipidus Arginine vasopressin receptor 2 gene mutation New site Diarrhea Case report

PCOSt:A non-invasive and cost-effective screening tool for polycystic ovary syndrome

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The Innovation 2023年第2期4卷 34-36页

作者： Huiyu xu Guoshuang Feng Li Shi yong Han Qin Huang Rong Li Center for Reproductive Medicine Department of Obstetrics and GynecologyPeking University Third HospitalBeijing 100191China National Clinical Research Center for Obstetrics and Gynecology Peking University Third HospitalBeijing 100191China Key Laboratory of Assisted Reproduction Peking UniversityMinistry of EducationBeijing 100191China Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology Beijing 100191China Big Data Center Beijing Children’s HospitalCapital Medical UniversityNational Center for Children’s HealthBeijing 100045China Hangzhou Qingguo Medical Technology Co. Ltd.HangzhouZhejiang 310000China

Dear Editor,Polycystic ovary syndrome(PCOS)affects more than 1 in 10 women worldwide.^(1)Despite its high prevalence,PCOS and its accompanying morbidities are likely underdiagnosed.^(2)To induce a PCOS-like phenotype in animals,testosterone and dihydrotestosterone are usually used,indicating that androgen excess is a major contributor to PCOS.^(3)Anti-M€ullerian hormone(AMH)is an upstream regulator of androgen and is well correlated with the androgens.

关键词： testosterone prevalence likely

Studies on aluminum powder combustion in detonation environment

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Chinese Physics B 2022年第4期31卷 426-435页

作者： jian-Xin Nie Run-Zhe Kan Qing-Jie Jiao Qiu-Shi Wang xue-yong Guo Shi Yan State Key Laboratory of Explosion Science and Technology Beijing Institute of TechnologyBeijing 100081China

The combustion mechanism of aluminum particles in a detonation environment characterized by high temperature(in unit 10^(3)K),high pressure(in unit GPa),and high-speed motion(in units km/s)was studied,and a combustion model of the aluminum particles in detonation environment was *** on this model,a combustion control equation for aluminum particles in detonation environment was *** can be seen from the control equation that the burning time of aluminum particle is mainly affected by the particle size,system temperature,and diffusion *** calculation result shows that a higher system temperature,larger diffusion coefficient,and smaller particle size lead to a faster burn rate and shorter burning time for aluminum *** considering the particle size distribution characteristics of aluminum powder,the application of the combustion control equation was extended from single aluminum particles to nonuniform aluminum powder,and the calculated time corresponding to the peak burn rate of aluminum powder was in good agreement with the experimental electrical conductivity *** equation can quantitatively describe the combustion behavior of aluminum powder in different detonation environments and provides technical means for quantitative calculation of the aluminum powder combustion process in detonation environment.

关键词： aluminum particle combustion model aluminum powder burn rate equation burning time

Simultaneous polyandry and heteropaternity in tiger(Panthera tigris altaica):Implications for conservation of genetic diversity in captive populations of felids

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Chinese Science Bulletin 2013年第17期58卷 2230-2236页

作者： LIU Dan MA Yue LI HuiYi xu YanChun ZHANG Yan DAHMER Thomas BAI SuYing WANG jian Heilongjiang Siberian Tiger Park State Forestry Administration Detecting Center of Wildlife College of Wildlife ResourcesNortheast Forestry University Ecosystems Ltd. Forensic Laboratory of Public Security Department of Heilongjiang Province

Male tigers(Panthera tigris altaica) in captivity copulate alternatively with an estrous female,suggesting a potential for heteropaternity as an effective reproductive strategy to maximize genetic diversity of *** analyzed microsatellites to test and compare the genetic output of multiple male mating(simultaneous polyandry) and single male mating(monogamy) with a female in a captive *** polyandry resulted in heteropaternity in 66.7% observed *** significant differences between parental populations and between offspring populations were detected in the number of alleles(A),expected heterozygosity(H e),number of effective alleles(N e) per locus and standard individual heterozygosity(SH)(P>0.05 for all 4 indexes).Comparisons showed no significant reduction of A,H o,H e and SH from parental population to offspring population for the two mating modes(P>0.05) except for SH in polyandrous families(P=0.029).However,such reduction was equivalent to single mating families when the influence of relatedness was eliminated using effective SH(E SH)(P>0.05).These results highlight an alternative strategy for managing captive populations of tiger and other wild felids in which animals are combined at one location allowing for copulation by multiple males to encourage heteropaternity in favor of maintained genetic diversity among offspring.

关键词：遗传多样性保护圈养种群猫科动物东北虎一夫一妻制等位基因数 Pgt 杂合度

The Steric Effect of trans-(1S,2S)-1-Substituted-2-(N,N-dialkyl-amino)-1-indanol Derivatives as Chiral Ligands in the Catalytic Enantioselective Addition of Diethylzinc to Aldehydes

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Chinese Chemical Letters 2002年第11期13卷 1029-1032页

作者： Qian yong xu Hong Fang YANG Xin Fu PAN Guang Ming ZHU Northwest Institute of Nuclear Technology P.O.Box 69Xi'an 710024 Department of Chemistry National Laboratory of Applied Organic ChemistryLanzhou UniversityLanzhou 730000 Department of Chemical Engineering Northwestern Polytechnic UniversityXi'an 710062

Optically active trans-(1S,2S)-1-substituted-2-(N,N-dialkylamino)-1-indanol derivatives have been prepared and used in the asymmetric addition of diethylzinc to aldehydes to give sec-alcohol in good yield with up to 9... 详细信息

关键词： Diethylzinc enantioselective alkylation indanol derivative.

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多变量公钥密码扩展方案的安全性分析

计算机学报 2013年第6期36卷 1177-1182页

作者：聂旭云徐赵虎廖永建钟婷电子科技大学计算机科学与工程学院成都611731 网络与数据安全四川省重点实验室成都611731 中国科学院信息工程研究所信息安全国家重点实验室北京100093 上海市信息安全综合管理技术研究重点实验室上海200240

扩展的多变量公钥密码方案(Extended Multivariate Public Key Cryptosystem,EMC)是Wang等人在2011年提出的一种新的增强多变量公钥加密体制安全性的方法,其核心是在加密之前先对明文变量进行一次基于杂凑函数的驯顺变换(Hash-based Tam... 详细信息

扩展的多变量公钥密码方案(Extended Multivariate Public Key Cryptosystem,EMC)是Wang等人在2011年提出的一种新的增强多变量公钥加密体制安全性的方法,其核心是在加密之前先对明文变量进行一次基于杂凑函数的驯顺变换(Hash-based Tame Transformation,简称HT变换)处理.Wang等人将EMC方法和加方法相结合构造出了多变量加密方案HTTP(Hash-based tame and plus).作者声称HTTP方案可以抵挡现有的对多变量公钥密码体制的攻击.文中对EMC方案和HTTP加密方案进行了安全性分析,分析结果表明EMC方案并没有真正增强原始多变量公钥密码体制的安全性.如果存在一种攻击方法可恢复原始的多变量公钥加密体制的合法密文对应的明文,那么同样可以恢复增强后的加密方案的合法密文对应的明文.计算机实验表明,我们的攻击是有效的.

关键词：多变量公钥密码扩展方案线性化方程 HT变换

Efficacy of Intragastric Balloons in the Markers of Metabolic Dysfunction-associated Fatty Liver Disease:Results from Meta-analyses

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Journal of Clinical and Translational Hepatology 2021年第3期9卷 353-363页

作者： Zi-Yuan Zou Jing Zeng Tian-Yi Ren Yi-Wen Shi Rui-xu Yang jian-Gao Fan Center for Fatty Liver Department of GastroenterologyXinhua Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai Key Lab of Pediatric Gastroenterology and NutritionShanghaiChina

Background and Aims:Nonalcoholic fatty liver disease,now renamed metabolic dysfunction-associated fatty liver disease(MAFLD),is common in obese *** balloon(IGB),an obesity management tool with low complication risk,might be used in MAFLD treatment but there is still unexplained heterogeneity in results across ***:We conducted a systematic search of 152 citations published up to September ***-analyses,stratified analyses,and meta-regression were performed to evaluate the efficacy of IGB on homeostasis model assessment of insulin resistance(HOMA-IR),alanine aminotransferase(ALT),aspartate aminotransferase(AST),and gamma-glutamyl transpeptidase(GGT),and to identify patients most appropriate for IGB ***:Thirteen observational studies and one randomized controlled trial met the inclusion criteria(624 participants in total).In the overall estimate,IGB therapy significantly improved the serum markers change from baseline to follow-up[HOMA-IR:1.56,95%confidence interval(CI)=1.16–1.95;ALT:11.53 U/L,95%CI=7.10–15.96;AST:6.79 U/L,95%CI=1.69–11.90;GGT:10.54 U/L,95%CI=6.32–14.75].In the stratified analysis,there were trends among participants with advanced age having less change in HOMA-IR(1.07 vs.1.82).The improvement of insulin resistance and liver biochemistries with swallowable IGB therapy was no worse than that with endoscopic *** meta-regression analyses showed that greater HOMA-IR loss was predicted by younger age(p=0.0107).Furthermore,effectiveness on ALT and GGT was predicted by basal ALT(p=0.0004)and GGT(p=0.0026),***:IGB is effective among the serum markers of *** patients had a greater decrease of HOMA-IR after IGB therapy.

关键词： Intragastric balloon Nonalcoholic fatty liver disease Insulin resistance Age groups Treatment outcome