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A Localization Method of High Energy Transients for All-sky Gamma-ray Monitor

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Research in Astronomy and Astrophysics 2024年第10期24卷 25-35页

作者： Yi Zhao Wangchen xue Shaolin Xiong Qi Luo Yuanhao Wang Jiacong Liu Heng Yu Xiaoyun Zhao Yue Huang Jinyuan Liao Jianchao Sun Xiaobo Li Qibin Yi Ce Cai Shuo Xiao Shenglun Xie Chao Zheng Yanqiu Zhang Chenwei Wang Wenjun Tan Zhiwei Guo Chaoyang Li Zhenghua An Gang Chen Yanqi Du Min Gao Ke Gong Dongya Guo Jiang He Jianjian He Bing Li Gang Li Xinqiao Li Jing Liang Xiaohua Liang Yaqing Liu Xiang Ma Rui Qiao Liming Song Xinying Song Xilei Sun Jin Wang Ping Wang Xiangyang Wen Hong Wu yanbing xu Sheng Yang Dali Zhang Fan Zhang Hongmei Zhang Peng Zhang Shu Zhang Zhen Zhang Shijie Zheng Keke Zhang Xingbo Han Haiyan Wu Hu Tai Hao Geng Gaopeng Lu Wei xu Fanchao Lyu Hongbo Zhang Fangjun Lu Shuangnan Zhang Department of Astronomy Beijing Normal UniversityBeijing 100875China Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Beijing 100049China School of Physics and Optoelectronics Xiangtan UniversityXiangtan 411105China College of Physics Hebei Normal UniversityShijiazhuang 050024China Guizhou Provincial Key Laboratory of Radio Astronomy and Data Processing Guizhou Normal UniversityGuiyang 550001China School of Physics and Electronic Science Guizhou Normal UniversityGuiyang 550001China Institute of Astrophysics Central China Normal UniversityWuhan 430079China College of physics Sciences Technology Hebei UniversityBaoding 071002China Physics and Space Science College China West Normal UniversityNanchong 637002China School of Computing and Artificial Intelligence Southwest Jiaotong UniversityChengdu 611756China College of Electronic and information Engineering Tongji UniversityShanghai 201804China Innovation Academy for Microsatellites of Chinese Academy of Sciences Shanghai 201304China National Space Science Center Chinese Academy of SciencesBeijing 100190China School of Earth and Space Sciences University of Science and Technology of ChinaHefei 230026China Electronic Information School Wuhan UniversityWuhan 430072China Key Laboratory of Transportation Meteorology of China Meteorological Administration Nanjing Joint Institute for Atmospheric SciencesNanjing 210000China Key Laboratory of Middle Atmosphere and Global Environment Observation Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China

Fast and reliable localization of high-energy transients is crucial for characterizing the burst properties and guiding the follow-up *** based on the relative counts of different detectors has been widely used for all-sky gamma-ray *** are two major methods for this count distribution localization:χ^(2)minimization method and the Bayesian *** we propose a modified Bayesian method that could take advantage of both the accuracy of the Bayesian method and the simplicity of the χ^(2)*** comprehensive simulations,we find that our Bayesian method with Poisson likelihood is generally more applicable for various bursts than the χ^(2)method,especially for weak *** further proposed a location-spectrum iteration approach based on the Bayesian inference,which could alleviate the problems caused by the spectral difference between the burst and location *** method is very suitable for scenarios with limited computation resources or timesensitive applications,such as in-flight localization software,and low-latency localization for rapidly follow-up observations.

关键词： methods:data analysis methods:analytical (stars:)gamma-ray burst:general

Archaea, the tree of life, and cellular evolution in eukaryotes

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Science China Earth Sciences 2019年第3期62卷 489-506页

作者： Jing XIAO Lu FAN Dingfeng WU yanbing xu Dengxun LAI William F.MARTIN Ruixin ZHU Chuanlun ZHANG Department of Bioinformatics Tongji University Shenzhen Key Laboratory of Marine Archaea Geo-Omics Department of Ocean Science and Engineering Southern University of Science and Technology SUSTech Academy for Advanced Interdisciplinary Studies Southern University of Science and Technology Institute of Molecular Evolution Heinrich-Heine-University Universit?tsstr.1 Laboratory for Marine Geology Qingdao National Laboratory for Marine Science and Technology

The early history of life harbours many unresolved evolutionary questions, none more important than the genomic origin and cellular evolution of eukaryotes. An issue central to eukaryote origin concerns the position of eukaryotes in the tree of life and the relationship of the host lineage that acquired the mitochondrion some two billion years ago to lineages of modern-day archaea. Recent analyses indicate that the host lineage branches within the Archaea, prompting the search for novel archaeal lineages that can improve our understanding of the cellular evolution of eukaryotes. Here we give a brief review of the studies on Archaea, the tree of life and the cellular evolution of eukaryotes, which is followed by an overview of recent progress fueled by new genomic technologies and recent status of archaeal research in China. Future directions for the study of early evolution are considered.

关键词： Archaea Tree of life Cellular evolution of eukaryotes Metagenomics Bioinformatics

Effect of tumor necrosis factor inhibitors on rheumatoid arthritis-induced peripheral neuropathy A cohort study

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Neural Regeneration Research 2012年第11期7卷 862-866页

作者： Naizhi Wang Yingying Guo Lili Yang Wenyi Fu yanbing xu Linxin Hou Shuai Zhao Ning Zhang Department of Rheumatism Shengjing Hospital China Medical University Shenyang 110004 Liaoning Province China

In this historical cohort study, 236 patients with primary rheumatoid arthritis were treated with the tumor necrosis factor inhibitors, etanercept or infliximab （n = 80）, or by conventional methods （n = 156）. Results revealed that 11 patients developed varying types of peripheral neuropathy at 1-2 years post-treatment （mean 16 months）. The incidence of peripheral neuropathy in the tumor necrosis factor inhibitors treatment group was 8.8% （7/80）, which was significantly higher than the conventional treatment group （2.6%; 4/156）. The relative risk of developing peripheral neuropathy in the tumor necrosis factor inhibitors treatment group was 3.41 （95% confidence interval： 1.03 11.31）. Comparison of the tumor necrosis factor inhibitors revealed that etanercept and infliximab had no significant difference in terms of inducing peripheral neuropathy. Experimental findings indicate that tumor necrosis factor inhibitors may increase the risk of peripheral neuropathy.

关键词： tumor necrosis factor inhibitors adverse reactions peripheral neuropathy rheumatoid arthritis cohort study risk factors

Structure-guided protein design of fluoroacetate dehalogenase for kinetic resolution of rac-2-bromobutyric acid

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Green Synthesis and Catalysis 2020年第1期1卷 60-65页

作者： Shu Wang Zhanbing Cheng yanbing xu Lu Yang Jian-Bo Wang Zhenhua Tian xudong Qu Shanghai R&D Center Abiochem Co.Ltd.Shanghai 200241China State Key Laboratory of Microbial Metabolism School of Life Sciences and BiotechnologyShanghai Jiao Tong UniversityShanghai 200240China Key Laboratory of Phytochemistry R&D of Hunan Province and Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research(Ministry of Education)College of Chemistry and Chemical EngineeringHunan Normal UniversityChangsha 410081China

R-2-Bromobutyric acid is a very important intermediate for the synthesis of agrochemicals and *** of rac-2-bromobutyric acid(rac-2-BBA)provides a promising process for R-2-bromobutyric acid(R-2-BBA)*** fluoroacetate dehalogenase(FAcD)has been always studied in the defluorination *** found that FAcD RPA1163 showed detectable activity but no enantioselectivity towards *** iterative saturation mutagenesis(ISM)of FAcD RPA1163 resulted in a mutant H155V/W156R/Y219M,which catalyzed the kinetic resolution of rac-2-BBA to produce R-2-BBA with enhanced activity and enantioselectivity(99.3%ee).The high preference for S-2-bromobutyric acid(S-2-BBA)is of synthetic *** docking analysis indicated that the H155V/W156R/Y219M mutation reduced steric hindrance and broadened the halide *** is not only the steric hindrance but also the electrostatic environment that has an effect on the activity and enantioselectivity.

关键词： Fluoroacetate dehalogenase Semi-rational design Enzyme engineering Kinetic resolution 2-bromobutyric acid

Rank-generating functions and Poincaré polynomials of lattices in finite orthogonal space of even characteristic

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Frontiers of Mathematics in China 2024年第4期19卷 181-189页

作者： Feng xu yanbing ZHAO Yuanji HUO Office of Academic Affairs Xuanhua Vocational College of Science and TechnologyZhangjiakou 075100China Department of Basic Courses Zhangjiakou Vocational and Technical CollegeZhangjiakou 075051China Department of Mathematics Hebei North UniversityZhangjiakou 075000China

The geometry of classical groups over finite fields is widely used in many *** this paper,we study the rank-generating function,the characteristic polynomial,and the Poincarépolynomial of lattices generated by the or... 详细信息

关键词： Lattices orthogonal space of even characteristic rank-generating function characteristic polynomial Poincarépolynomial

New heavy neutron-rich isotope ^(238)Th

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Nuclear Science and Techniques 1999年第2期10卷 65-68页

作者： xu yanbing YUAN Shuanggui YANG Weifan LI Zongwei MA Taotao XIONG Bing HE Jianjun(Institute of Modern Physics, the Chinese Academy of Sciences, Lanzhou 730000) Institute of Modern Physics Chinese Academy of Sciences Lanzhou 730000 China

A new nuclide (238)Th has been produced via multinucleon transferreaction by 60 MeV/u 18O ion irradiation of the natural uranium. The thorium wasradiochemically separated from the fixture of uranium and reaction products. Theactivity of thorium was measured by using an HPGe detector and a planar HPGedetector. The 238Th has been identified for the first time by measuring the growthand decay of the 7-rays from its daughter 238Pa. The half-life of 238Th was determinedto be 9.4f2.0 min. In addition, a new 7-ray of 89.010.3 keV with TI/2=8.911.5minwas found in the 7 spectrum gated with X-rays of Pa and assigned to 238Th P-- decaybased on measurements of transition energy and half life.

关键词：富中子同位素 ^238Th 多核子迁移反应

Production Cross-section of ^236Th in Interaction of ^238U with 60 MeV/u ^18O Ions

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近代物理研究所和兰州重离子加速器实验室年报：英文版 2007年第1期 48-49页

作者： Yang Weifan Yuan Shuanggui xu yanbing Ding Huajie

Cellular and Transcriptional Dynamics during Brown Adipose Tissue Regeneration under Acute Injury

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Research 2024年第3期2023卷 345-357页

作者： Wenjing You Ziye xu Wentao Chen Xin Yang Shiqi Liu Liyi Wang Yuang Tu yanbing Zhou Teresa G.Valencak Yizhen Wang Shihuan Kuang Tizhong Shan College of Animal Sciences Zhejiang UniversityHangzhouChina The Key Laboratory of Molecular Animal Nutrition Ministry of EducationHangzhouChina Zhejiang Provincial Laboratory of Feed and Animal Nutrition HangzhouChina Department of Laboratory Medicine the First Affiliated HospitalCollege of MedicineZhejiang UniversityHangzhouChina Department of Animal Sciences Purdue UniversityWest LafayetteINUSA.

Brown adipose tissue(BAT)is the major site of non-shivering thermogenesis and crucial for systemic *** chronic cold exposures and high-fat diet challenges,BAT undergoes robust remodeling to adapt to physiological ***,whether and how BAT regenerates after acute injuries are poorly ***,we established a novel BAT injury and regeneration model(BAT-IR)in mice and performed single-cell RNA sequencing(scRNA-seq)and bulk RNA-seq to determine cellular and transcriptomic dynamics during *** further defined distinct fibro-adipogenic and myeloid progenitor populations contributing to BAT *** trajectory and gene expression analyses uncovered the involvement of MAPK,Wnt,and Hedgehog(Hh)signaling pathways in BAT *** confirmed the role of Hh signaling in BAT development through Myf5Cre-mediated conditional knockout(cKO)of the Sufu gene to activate Hh signaling in BAT and muscle *** BAT-IR model therefore provides a paradigm to identify conserved cellular and molecular mechanisms underlying BAT development and remodeling.

关键词： injuries involvement acute

任意干湿路径下非饱和岩土介质的土水特征关系模型

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岩石力学与工程学报 2008年第5期27卷 1046-1052页

作者：徐炎兵韦昌富陈辉栾茂田中国科学院武汉岩土力学研究所岩土力学与工程国家重点实验室湖北武汉430071t 大连理工大学土木水利学院辽宁大连116024

土水特征曲线(SWCC)代表着基质吸力与含水量关系不是一一对应的,在反复干湿循环路径下该曲线呈现出循环滞回特性。岩土介质在经历反复干湿循环之后,部分气体会以气泡的形式残留于孔隙中;这种残留的气体会对土水特征关系和流体的渗透系... 详细信息

土水特征曲线(SWCC)代表着基质吸力与含水量关系不是一一对应的,在反复干湿循环路径下该曲线呈现出循环滞回特性。岩土介质在经历反复干湿循环之后,部分气体会以气泡的形式残留于孔隙中;这种残留的气体会对土水特征关系和流体的渗透系数产生重要影响。基于毛细循环滞回的内变量理论和传统的土水特征关系经验模型,提出了一个能模拟在任意干湿循环路径下土水特征关系的数学模型。特别地,该模型考虑了介质中的残余含气量对循环土水特征关系的影响。在循环滞回边界给定的情况下,该模型只包含一个材料参数;该材料参数可以由任意一条一阶扫描线(或其上的一个数据点)来确定。利用所提出的数学模型结合欧拉迭代计算方法,对已有文献中的粉土、烧结玻璃珠、石灰岩及白云岩等不同岩土介质在任意干湿循环路径下的SWCC试验曲线进行了模拟。通过将预测结果与现有试验数据进行对比,验证了该模型对描述复杂干湿循环路径下的土水特征关系的有效性。

关键词：土力学非饱和岩土介质土水特征关系干湿循环毛细滞回残余含气量