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Fiducial intervals of restricted parameters and their applications

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Science china mathematics 2005年第11期48卷 1567-1583页

作者： li Xinmin, li guoying & xu xingzhong College of mathematics and Information Sciences, Shandong University of technology, Zibo 255049, china Academy of mathematics and System Sciences, Chinese Academy of Sciences, beijing 100800, china department of mathematics, beijing institute of technology, beijing 100801, china 1. College of mathematics and Information Sciences Shandong University of Technology 255049 Zibo China 2. Academy of mathematics and System Sciences Chinese Academy of Sciences 100800 Beijing China 3. department of mathematics Beijing Institute of Technology 100801 Beijing China

In practice, the unknown parameters are often restricted. This paper provides a general method for constructing the fiducial intervals of the restricted parameters. Applying the general method, the fiducial intervals are constructed for the location (scale)parameters and the difference (ratio) of two locations (scales) in a location (scale) family of distributions. The frequency properties of these intervals are verified. For a variance components model, the fiducial intervals for the three parameters of common interest are obtained. Their frequency properties are investigated theoretically and computationally.

关键词： restricted parameter space,fiducial interval,frequency property,variance components

GENERAliZED p-VALUES FOR TESTING REGRESSION COEFFICIENTS IN PARTIALLY liNEAR MODELS

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Journal of Systems Science & Complexity 2010年第6期23卷 1118-1132页

作者： Huimin HU xingzhong xu guoying li School of Statistics and mathematics Shandong University of Finance Jinan 250014 China. department of mathematics Beijing Institute of Technology Beijing 100081 China. Academy of mathematics and Systems Science Chinese Academy of Sciences Beijing 100190 China.

The one-sided and two-sided hypotheses about the parametric component in partially linear model are considered in this paper. Generalized p-values are proposed based on fiducial method for testing the two hypotheses at the presence of nonparametric nuisance parameter. Note that the nonparametric component can be approximated by a linear combination of some known functions, thus, the partially linear model can be approximated by a linear model. Thereby, generalized p-values for a linear model are studied first, and then the results are extended to the situation of partially linear model. Small sample frequency properties are analyzed theoretically. Meanwhile, simulations are conducted to assess the finite sample performance of the tests based on the proposed p-values.

关键词： Fiducial inference frequency property generalized p-value hypothesis testing partially linear model.

C:N:P stoichiometry of Ericaceae species in shrubland biomes across Southern china:influences of climate,soil and species identity

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Journal of Plant Ecology 2019年第2期12卷 346-357页

作者： Qiang Zhang Qing liu Huajun Yin Chunzhang Zhao lin Zhang guoying Zhou Chunying Yin Zhijun Lu Gaoming Xiong Yuelin li Jiaxiang li Wenting xu Zhiyao Tang Zongqiang Xie State Key Laboratory of Vegetation and Environment Change Institute of BotanyChinese Academy of SciencesBeijing 100093China University of Chinese Academy of Sciences Beijing 100049China Key laboratory of Mountain Ecological Restoration and Bioresource Utilization&Ecological Restoration and Biodiversity Conservation Key Laboratory of Sichuan Province Chengdu Institute of BiologyChinese Academy of SciencesChengdu 610041China Key Laboratory of Alpine Ecology and Biodiversity of Chinese Academy of Sciences Institute of Tibetan Plateau ResearchChinese Academy of SciencesBeijing 100101China Northwest institute of Plateau Biology Chinese Academy of SciencesXining 810008 Key Laboratory of Aquatic Botany and Watershed Ecology Wuhan Botanical GardenChinese Academy of SciencesWuhan 430074China South china Botanical Garden Chinese Academy of SciencesGuangzhou 510650China College of Forest Central South University of Forestry&TechnologyChangsha 410004China department of Ecology College of Urban and Environmental Sciences and Key Laboratory for Earth Surface ProcessesPeking UniversityBeijing 100871China

Aims Carbon(C),nitrogen(N)and phosphorus(P)stoichiometry strongly affect functions and nutrient cycling within ***,the related researches in shrubs were very *** this study,we aimed to inves-tigate leaf stoichiometry and its driving factors in shrubs,and whether stoichiometry significantly differs among closely related *** We analyzed leaf C,N and P concentrations and their ratios in 32 species of Ericaceae from 161 sites across southern *** examined the relationships of leaf stoichiometry with environmen-tal variables using linear regressions,and quantified the interactive and independent effects of climate,soil and species on foliar stoi-chiometry using general linear models(GLM).Important Findings The foliar C,N and P contents of Ericaceae were 484.66,14.44 and 1.06 mg g−1,*** C,N and P concentrations and their ratios in Ericaceae were significantly related with latitude and altitude,except the N:P insignificantly correlated with ***(mean annual temperature and precipitation)and soil properties(soil C,N and P and bulk density)were significantly influenced element *** GLM analysis showed that soil exerted a greater direct effect on leaf stoichiometry than climate did,and climate affected leaf traits mainly via indirect ***,soil properties had stronger influ-ences on leaf P than on leaf C and *** all independent factors examined,we found species accounted for the largest proportion of the variation in foliar *** results suggest that species can largely influence foliar stoichiometry,even at a lower taxonomic level.

关键词： biogeographic pattern phylogenetic effect closely related species,Ericoid Mycorrhiza shrub

Effect of a modified Banxia Xiexin decoction plus chemotherapy on stage Ⅲ colon cancer

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Journal of Traditional Chinese Medicine 2019年第2期39卷 251-257页

作者： li Kai liu Rui xu Guangzhong Zhang Weihua liu Chen Zhu Bin Hua Baojin Feng xingzhong department of oncological surgery Beijing Shijitan Hospital Capital Medical University department of oncology Guang'anmen Hospital China Academy of Chinese Medical Sciences Traditional Chinese Medicine Beijing Shijitan Hospital Capital Medical University

OBJECTIVE: To investigate the effect of a modified Banxia Xiexin decoction(MBXD) plus chemotherapy on postoperative adverse reaction in patients with stage Ⅲ colon cancer in patients whose symptoms were identified as cold-heat complicated pattern in terms of the theory of Traditional Chinese Medicine(TCM).METHODS: A prospective non-randomized control study of patients with stage Ⅲ colon cancer in beijing Shijitan Hospital and Guang'anmen Hospital between January 2012 and December 2013. A total of 80 patients were divided into experimental group(MBXD + chemotherapy) and control group(chemotherapy). The adverse reactions, life quality and disease-free survival(DFS) were compared between the two ***: The cold-heat complex pattern was released in 94.3% of patients in experimental group whereas 62.2% in control group(P life quality was improved in 24 vs 14 cases, stabilized in 9 vs14 cases whereas decreased in 2 vs 15 cases in experimental group and control group, respectively(P lieve clinical symptoms, reduce chemotherapy associated adverse effects, improve life quality, and prolong DFS of patients with stage Ⅲ colon cancer(cold-heat complicated pattern).

关键词： Colonic neoplasms Drug therapy Signs and symptoms Quality of life Disease-free survival Syndromes and signs Banxia Xiexin decoction

Discovery of carbon-based strongest and hardest amorphous material

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National Science Review 2022年第1期9卷 25-35页

作者： Shuangshuang Zhang Zihe li Kun Luo Julong He Yufei Gao Alexander V.Soldatov Vicente Benavides Kaiyuan Shi Anmin Nie Bin Zhang Wentao Hu Mengdong Ma Yong liu Bin Wen guoying Gao Bing liu Yang Zhang Yu Shu Dongli Yu Xiang-Feng Zhou Zhisheng Zhao Bo xu Lei Su Guoqiang Yang Olga P.Chernogorova Yongjun Tian Center for High Pressure Science (CHiPS) State Key Laboratory of Metastable Materials Science and Technology Yanshan University Key Laboratory for Microstructural Material Physics of Hebei Province School of Science Yanshan University department of Engineering Sciences and mathematics Lule a University of Technology department of Physics Harvard University Center for High Pressure Science and technology Advanced Research department of Materials Science Saarland University Key Laboratory of Photochemistry Institute of Chemistry University of Chinese Academy of Sciences Baikov institute of Metallurgy and Materials Science Russian Academy of Sciences

Carbon is one of the most fascinating elements due to its structurally diverse allo tropic forms stemming from its bonding varieties(sp,sp~2 and sp~3).Exploring new forms of carbon has been the eternal theme of scientific ***,we report on amorphous(AM) carbon materials with a high fraction of sp~3 bonding recovered from compression of fullerene C60 under high pressure and high temperature,previously *** of photoluminescence and absorption spectra demonstrates that they are semiconducting with a bandgap range of 1.5-2.2 eV,comparable to that of widely used AM *** mechanical tests demonstrate that synthesized AM-Ⅲ carbon is the hardest and strongest AM material known to date,and can scratch diamond crystal and approach its *** produced AM carbon materials combine outstanding mechanical and electronic properties,and may potentially be used in photovoltaic applications that require ultrahigh strength and wear resistance.

关键词： amorphous carbon ultrahard ultrastrong semiconductor phase transition

Vitamin D in ankylosing spondylitis:Review and meta-analysis

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Vitamin D in ankylosing spondylitis:Review and meta-analysis

2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents

2015年度安徽省流行病与卫生统计学学术论坛

作者： Guoqi Cai li Wang Dazhi Fan lihong Xin li liu Yanting Hu Ning Ding Shengqian xu Guo Xia xingzhong Jin Jianhua xu Yanfeng Zou Faming Pan department of Epidemiology and Biostatistics School of Public HealthAnhui Medical University department of Rheumatism and Immunity The First Affiliated Hospital of Anhui Medical University Menzies Research institute Tasmania University of Tasmania

Background:The role of vitamin D in ankylosing spondylitis(AS) is largely *** paper aims to examine the association between serum vitamin D levels and susceptibility and disease activity of ***:We searched the relevant literatures in Pub Med,Elsevier Science Direct,Chinese Biomedical Database(CBM),Chinese National Knowledge Infrastructure(CNKI) and Wanfang(Chinese) Database published before June *** independent case–control studies with a total of 533 AS patients and 478 matching controls were selected into this *** mean differences(SMDs) with 95% confidence intervals(CIs)were used to assess the levels of serum vitamin D,parathyroid hormone(PTH),serum calcium and alkaline phosphatase(ALP) in cases and controls,*** coefficients(CORs) have been performed to value the correlationship between vitamin D and disease activity(erythrocyte sedimentation rate(ESR) and Creactive protein(CRP) and Bath Ankylosing Spondylitis Disease Activity Index(BASDAI)) of AS ***:Meta-analysis results suggested that vitamin D may play a protective role in AS(for total vitamin D:SMD =-0.71,Plity(SMD = 0.20,P = 0.04).The relationship between serum vitamin D levels and disease activity was statistically significant except for 25 OHD versus(vs.) CRP or BASDAI(for CRP vs.25OHD:COR =-0.22,P = 0.08;for BASDAI vs.25OHD:COR =-0.20,P = 0.06,respectively).Conclusion:The higher levels of serum vitamin D were associated with a decreased risk of AS,and showed an inverse relationship with AS activity.

关键词： Ankylosing spondylitis Serum vitamin D Disease activity Meta-analysis Systemic inflammation Alkaline phosphatase

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Science Bulletin 2018年第23期63卷 1558-1564页

作者： Cheng Wang Yaqi li Ying liao Hong Tian Min Huang Xiangyu Dong lin Shi Jinghui Sun Hongfang Jin Junbao Du Jindou An Jie Chen Mingwu Chen Qi Chen Sun Chen Yonghong Chen Zhi Chen Adolphus Kai-tung Chau Junbao Du Zhongdong Du Junkai Duan Hongyu Duan Xiangyu Dong lin Feng lijun Fu Fangqi Gong Yonghao Gui ling Han Zhenhui Han Bing He Zhixu He Xiufen Hu Yimin Hua guoying Huang Min Huang Ping Huang Yujuan Huang Hongfang Jin Mei Jin Bo li Fen li Tao li Xiaohui li Xiaoyan liu Yan li Haitao Lv Tiewei Lv Zipu li Luyi Ma Silin Pan Yusheng Pang Hua Peng Yuming Qin Jie Shen lin Shi Kun Sun Jinghui Sun Hong Tian Jie Tian Cheng Wang Hong Wang Lei Wang Jinju Wang Wendi Wang Yuli Wang Rongzhou Wu Tianhe Xia Yanyan Xiao Chunhong Xie Yanlin Xing Zhenyu Xiong Baoyuan xu Yi xu Hui Yan Shiwei Yang Qijian Yi Xia Yu Xianyi Yu Yue Yuan Hongyan Zhang Huili Zhang li Zhang Qingyou Zhang Xi Zhang Yanmin Zhang Zhiwei Zhang Cuifen Zhao Bin Zhou Hua Zhu department of Pediatric Cardiovasoloy Children's Medical CenterThe Second Xiangya HospitalCentral South UniversityChangsha 410071China department of Pediatrics Peking University First HospitalBeijing 100034China department of Pediatric Cardiology Children's Hospital of Fudan UniversityShanghai 201102China department of Pediatric Cardiology Shanghai Children's HospitalShanghai 207102China of Pediatrics the 2nd Hospital of Lanzhou UniversityLanzhou 730020China department of Pediatric Cardiology Capital Institute of PediatricsBezjing 100020China department of Pediatrics Jilin University First HospitalChangchun 130021China Chinese Pediatric Cardiology Society Chinese Pediatric Society(CPCS)Chinese Medical Association(CMA)China Committee on Pediatric Syncope Pediatricians BranchChinese Medical Doctor Association(CMDA)China Pediatric Cardiology Society Beijing Pediatric SocietyBeijing Medical Association(BMA)China Committee on Pediatric Cardiology Chinese College of Cardiovascular PhysiciansChinese Medical Doctor Association(CMDA)China

Syncope belongs to the transient loss of consciousness(TLOC), characterized by a rapid onset, short duration, and spontaneous complete recovery. It is common in children and adolescents, accounting for 1% to 2% of emergency department *** syncope can seriously affect children's physical and mental health, learning ability and quality of life and sometimes cardiac syncope even poses a risk of sudden death. The present guideline for the diagnosis and treatment of syncope in children and adolescents was developed for guiding a better clinical management of pediatric syncope. Based on the globally recent development and the evidence-based data in china, 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents was jointly prepared by the Pediatric Cardiology Society, Chinese Pediatric Society, Chinese Medical Association(CMA)/Committee on Pediatric Syncope, Pediatricians Branch, Chinese Medical Doctor Association(CMDA)/Committee on Pediatric Cardiology, Chinese College of Cardiovascular Physicians, Chinese Medical Doctor Association(CMDA)/Pediatric Cardiology Society, beijing Pediatric Society, beijing Medical Association(BMA). The present guideline includes the underlying diseases of syncope in children and adolescents, the diagnostic procedures, methodology and clinical significance of standing test and headup tilt test, the clinical diagnosis vasovagal syncope, postural orthostatic tachycardia syndrome, orthostatic hypotension and orthostatic hypertension, and the treatment of syncope as well as follow-up.

关键词： CPCS Children Adolescent syncope