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Assessment of POC CD4 Detecting Mode in District or County Labs-Jiangsu Province, China, 2021

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China CDC weekly 2022年第47期4卷 1059-1065,I0003页

作者： Zhi Zhang xiaoqin xu Chengqing Sun Jing Lu Haiyang Hu Ying Zhou Gengfeng Fu Department of HIV/STD Control and Prevention Jiangsu Provincial Center for Disease Control and PreventionNanjing CityJiangsu ProvinceChina School of Public Health Nanjing Medical UniversityNanjing CityJiangsu ProvinceChina.

Objective:This study seeks to explore efficient and multiple-item detection modes in new-style HIV labs,as well as access the accuracy and reliability of CD4 cell count detected by point of care(POC)to analyze POC work feasibility in district or county ***:POC devices adopted in grassroots-level labs and flow cytometers adopted in prefecture-level labs were used to analyze the same group of blood *** individual results were collected and compared for parametric tests in correlation and ***:The Pearson correlation coefficients(r)between results detected by FACSPresto and those by FACSCalibur,FACSVia,FACSCantoII,and EPICSXL were 0.922,0.938,0.914,and 0.823,respectively;the average deviations were−25.64,24.68,3.05,and 70.97 cells/μL,respectively;the Pearson correlation coefficient(r)between results by Pima and FACSCalibur,FACSVia,FACSCantoII,and EPICSXL were 0.900,0.950,0.954,and 0.876,respectively;and the average deviations were−73.99,−40.78,−29.32,and−22.75 cells/μL,***:Strong positive correlations and good consistency were observed between the CD4 count tested by POC and flow *** findings provide theoretical support for new-style HIV labs and one-stop services,which can provide shorter testing duration and simpler testing processes,so that the most comprehensive testing results can be obtained in the shortest amount of time.

关键词： testing simpler shortest

Yolk shell-structured pyrite-type cobalt sulfide grafted by nitrogen-doped carbon-needles with enhanced electrical conductivity for oxygen electrocatalysis

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Chinese Chemical Letters 2024年第7期35卷 212-217页

作者： Jiahao Xie Jin Liu Bin Liu Xin Meng Zhuang Cai xiaoqin xu Cheng Wang Shijie You Jinlong Zou Key Laboratory of Functional Inorganic Material Chemistry Ministry of Education of the People’s Republic of ChinaSchool of Chemistry and Materials ScienceHeilongjiang UniversityHarbin 150080China School of Chemical Engineering and Light Industry Guangdong University of TechnologyGuangzhou 510006China State Key Laboratory of Urban Water Resource and Environment School of EnvironmentHarbin Institute of TechnologyHarbin 150090China

Pyrite-type sulfides(PTS)exhibit promising intrinsic activities for oxygen reduction and evolution reactions(ORR/OER).However,their poor electrical conductivities may limit the charge transfer rate to inevitably lower ***,yolk-shell structured cobalt-pyrite nanospheres(CoS_(2)YSS)are prepared and modified with amino groups as nucleation sites for coupling highly-conductive needle-like nitrogendoped carbon via a facile solvothermal method(CoS_(2)YSS@NC).The as-marked CoS_(2)YSS@NC-0.5 shows a gap between yolk and shell,and an obvious exterior layer of grafted NC,which can provide an integrated structure,an interior place,and three exposed surfaces on CoS_(2).CoS_(2)YSS@NC-0.5 reveals higher ORR activity(half-wave potential of 0.88 V)and methanol resistance than commercial Pt/*** to in-situ formation of highly-active CoOOH,CoS_(2)YSS@NC-0.5 shows a better overpotential(244 mV at 10 mA/cm^(2))and Tafel slope(135 mV/dec)than ***-air battery with CoS_(2)YSS@NC-0.5 air-cathode exhibits good open circuit potential(1.44 V),specific capacity(772.5 mAh/g)and cycling ***-like NC layer coated on the yolk-shell structure of CoS_(2)effectively lowers the charge transfer resistance to obtain extraordinary ORR/OER *** indicates that the integration of highly-conductive carbon onto pyritetype sulfides is an effective strategy to acquire durable bifunctional ORR/OER catalysts.

关键词： Cobalt sulfides Cycle stability Electrical conductivity Pyrite Yolk-shell structure

Acid-Stable CoWO_(4)/WO_(3)-Microrod Coated by a Thin Carbon-Layer as Efficient Pt Co-Catalysts for Methanol Oxidation and Oxygen Reduction

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Chinese Journal of Structural Chemistry 2022年第7期41卷 59-67页

作者： Jiahuan Li Jiahao Xie Xinyu Wang Ying Dai xiaoqin xu Jin Liu Zhuang Cai Xin Meng Jinlong Zou Key Laboratory of Functional Inorganic Material Chemistry Ministry of Education of the People's Republic of ChinaSchool of Chemistry and Materials ScienceHeilongjiang UniversityHarbin 150080China School of Civil Engineering Heilongjiang Institute of TechnologyHarbin 150050China

Insufficient activity and instability(poisoning)of Pt-based electrocatalysts for methanol oxidation and oxygen reduction reactions(MOR/ORR)impede the development of direct methanol fuel ***,CoWO_(4) nanoparticles-loaded WO_(3) microrods coated by a thin carbon-layer are used as Pt-supports/co-catalysts for MOR/***_(3) grows along the(110)crystal plane to form microrod(diameter of~0.6 um),which is coated by a carbon-layer(~5 nm).Pt-CoWO_(4)/WO_(3)@NCL-mr(850℃)shows a higher mass activity(2208 mA mg^(-1)_(pt))than the commercial Pt/C(659.4 mA mg^(-1)_(pt)).CoWO_(4)/WO_(3) heterojunction on the microrod surface with abundant oxygen vacancies allows the generation of surface-adsorbed hydroxyl to facilitate CO elimination and regeneration of the occupied Pt active-sites(promising stability).PtCo WO_(4)/WO_(3)@NCL-mr(850℃)has higher half-wave(0.46 V)and onset(0.54 V)potentials than Pt/C(0.41 and 0.50 V)for *** microrod structure of Co WO_(4)/WO_(3)@NCL facilitates the dispersibility of Pt NPs to increase the utilization of Pt active sites and relieve the self-aggregation of Pt to obtain a promising synergy between Pt and CoWO_(4)(Co^(2+))for ORR in acid *** study provides insights not only into the synthesis of acid-resistant WO_(3)@NCL microrod as active Pt co-catalyst,but also into the effective utilization of surface oxygen vacancies and Co^(2+) for MOR/ORR.

关键词： acid resistance methanol-tolerance oxygen vacancies strong metal-support interaction thin carbon-layer

Seasonal variations in the plant diet of the Chinese Monal revealed by fecal DNA metabarcoding analysis

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Avian Research 2022年第2期13卷 208-215页

作者： Bin Wang Yun Li Guiquan Zhang Jian Yang Cao Deng Haoyu Hu Long Zhang xiaoqin xu Caiquan Zhou Key Laboratory of Southwest China Wildlife Resources Conservation(Ministry of Education) China West Normal UniversityNanchong637002China Institute of Ecology China West Normal UniversityNanchong637002China Key Laboratory of State Forestry and Grassl and Administration on Conservation Biology of Rare Animalsin the Giant Panda National Park(China Conservation and Research Center for the Giant Panda) Dujiangyan611830China Key Laboratory of Animal Disease and Human Health of Sichuan Province College of Veterinary MedicineSichuan Agricultural UniversityChengdu611130China Institute of Chinese Materia Medica China Academy of Chinese Medical SciencesBeijing100700China

The Chinese Monal(Lophophorus thuysii)is an alpine-obligate galliform species of global conservation *** has been listed as a first class protected wildlife species in China,requiring conservation actions during the 14 th Five-Year Plan ***,the diet composition of Chinese Monal and its seasonal variations have rarely been studied,constraining the effective conservation of the ***,we investigated the plant diet composition of the Chinese Monal and its seasonal variations using a DNA metabarcoding approach on fecal *** collected 190 fecal samples of the Chinese Monals from the central Qionglai Mountains located in China,and analyzed the plant diet of this species using a DNA metabarcoding *** profiling of higher plants in the fecal samples was performed using the second internal transcribed spacer(ITS2)*** analyses,including rarefaction curves,nonmetric multidimensional scaling(NMDS)and permutational multivariate analysis of variance(PERMANOVA),were used to explore the seasonal variations in diet *** Chinese Monal foraged a wide range of plant recipes composed of 35 families and 83 genera throughout the year,with Brassicaceae,Apiaceae,and Poaceae as the dominant families,and Cardamine as the dominant *** species consumed plants from 62 genera from 28 families during the breeding season(n=81)and 66 genera from 31 families during the non-breeding season(n=109).Further,the plant diet composition significantly varied between the breeding and non-breeding seasons,especially for the frequency of occurrence and relative read abundances at genus *** study analyzed the plant diet of the Chinese Monal at a high resolution for the first time,and the results revealed that the seasonal variations in its plant diet composition was adapted to plant phenology and foraging *** species,a previously confirmed important food resource for the Chinese Monal,were not detected in any fe

关键词： Chinese monal Conservation management Diet seasonality DNA metabarcoding Endangered species

Postnatal feeding with high-fat diet induces obesity and precocious puberty in C57BL/6J mouse pups： a novel model of obesity and puberty

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Frontiers of Medicine 2017年第2期11卷 266-276页

作者： Rahim Ullah Yan Su Yi Shen Chunlu Li xiaoqin xu Jianwei Zhang Ke Huang Naveed Rauf Yang He Jingjing Cheng Huaping Qin Yu-Dong Zhou Junfen Fu Department of Endocrinology Children's Hospital Zhejiang University School of Medicine Hangzhou 310051 China Department of Neurobiology Institute of Neuroscience and the Collaborative Innovation Center for Brain Science Key Laboratory of Medical Neurobiology of the Ministry of Health of China Zhejiang University School of Medicine Hangzhou 310058 China

Childhood obesity and obesity-related metabolic complications are induced by a high-fat postnatal diet. The lack of a suitable animal model, however, remains a considerable challenge in obesity studies. In the current study, we provided high-fat diet （HFD） to dams during lactation and to pups after weaning. We also developed a novel model of C57BL/6J mouse pups with HFD-induced postnatal obesity. Results showed that feeding with HFD induces fat deposition and obesity in pups. Furthermore, HFD more potently increased the body weight （BW） of male than female pups. HFD-fed female pups were obese, underwent precocious puberty, and showed increased kisspeptin expression in the hypothalamus. However, parental obesity and precocious puberty exerted no synergistic effects on the HFD-induced postnatal weight gain and puberty onset of the pups. Interestingly, some HFD-fed litters with normal BW also exhibited precocious puberty. This finding suggested that diet composition but not BW triggers puberty onset. Our model suggests good construction validity of obesity and precocious puberty. Furthermore, our model can also be used to explore the mutual interactions between diet-induced postnatal childhood obesity and puberty.

关键词： postnatal HFD feeding obesity kisspeptin HPG axis precocious puberty

零被引论文产生的原因分析——以《植物营养与肥料学报》为例

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中国科技期刊研究 2015年第7期26卷 763-768页

作者：徐晓芹中国农业科学院农业资源与农业区划研究所<植物营养与肥料学报>编辑部北京市中关村南大街12号100081

【目的】通过综合定量分析同行评审专家对零被引论文学术价值和学术质量的评审意见,阐明科技论文发生零被引的内在原因。【方法】利用CNKI学术文献总库提取了《植物营养与肥料学报》1994—2012年发表的零被引论文,统计分析了零被引论文... 详细信息

【目的】通过综合定量分析同行评审专家对零被引论文学术价值和学术质量的评审意见,阐明科技论文发生零被引的内在原因。【方法】利用CNKI学术文献总库提取了《植物营养与肥料学报》1994—2012年发表的零被引论文,统计分析了零被引论文与论文第一作者类型的关系,利用保存的2008—2012年期间的同行专家审稿意见,对零被引论文的学术价值和学术质量评价指标进行了归纳总结和定量分析。【结果】不同类型作者对零被引论文贡献大小为研究生(47%)>副高(23%)>初中级(17%)>正高(13%);44%的同行评审专家认为,零被引论文涉及的科学问题属于国内领先,但超过90%的专家认为零被引论文的试验设计、研究方法和结果分析存在严重缺陷。【结论】严重的稿件质量问题与零被引论文产生密切相关,减少科技期刊论文的零被引率,需要"作者-审稿专家-编辑协同控制"。

关键词：科技论文零被引率学术价值论文质量审稿意见

MicroRNA-152 promotes non-alcoholic hepatic steatosis by suppressing the Wnt signaling pathway

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MicroRNA-152 promotes non-alcoholic hepatic steatosis by sup...

2018年浙江省医学会儿科学分会学术年会

作者： xiaoqin xu Yan Su Junfen Fu The Children’s Hospital Zhejiang University School of Medicine

During hepatic steatosis,aberrant microRNA expression profiles occur in association with the process of nonalcoholic fatty liver disease (NAFLD).We have previously shown that miR-152 increases during NAFLD in high-fat diet induced obese *** miR-152 is implicated in the regulation of hepatic metabolic functions is not *** this work,hepG2 cells and human hepatocytes were transfected with lentiviral-based hsa-miR-152 mimic (LentimiR-152),lentiviral-based hsa-miR-152 inhibitor (Lenti-152-In) or lentiviral-based negative control (Lenti-NC)to assess the role of miR-152 in hepatic steatosis.

关键词：

来源： cnki会议评论

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测控设备自主可控发展建设探讨

飞行器测控学报 2015年第2期34卷 133-139页

作者：徐小琴北京跟踪与通信技术研究所北京100094

针对测控设备国产化建设需求,全面阐释自主可控的概念,系统分析国家层面的自主可控基础软硬件产品发展现状,以及测控设备目前软硬件应用现状。分别针对国产和外购2款核心FPGA(Field-Programmable Gate Array,现场可编程门阵列)、DSP(Dig... 详细信息

针对测控设备国产化建设需求,全面阐释自主可控的概念,系统分析国家层面的自主可控基础软硬件产品发展现状,以及测控设备目前软硬件应用现状。分别针对国产和外购2款核心FPGA(Field-Programmable Gate Array,现场可编程门阵列)、DSP(Digital Signal Processing,数字信号处理)元器件,进行性能比对和应用分析,说明目前测控设备应用存在的问题和潜在的风险隐患,提出宏观层面的自主可控产业链发展建议,探讨测控设备自主可控建设发展思路。简单综述目前自主可控建设发展的几个成功案例。分析结果表明:目前测控设备自主可控已经具备了一定的软硬件国产化发展基础,其国产化建设势在必行。

关键词：测控设备自主可控国产化操作系统软硬件

The adsorption isotherms, IR and ^(29)Si MAS NMR spectra of modified MCM-41 molecular sieves

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Chinese Science Bulletin 1997年第10期42卷 828-832页

作者： LONG Yingcai, DONG Weiyang, xu Taiming, GAO xiaoqin, XIE Guangen and SUN Yaojun1. Department of Chemistry, Fudan University, Shanghai 200433, China 2. Centre of Analysis and Measurement, Fudan University, Shanghai 200433, China Department of Chemistry Fudan University Shanghai China Centre of Analysis and Measurement Fudan University Shanghai China

RECENTLY a new family of mesoporous molecular sieves,M41S,was reported by researchers atMobil R&D *** a member of the family,MCM-41,which exhibits a hexagonalarray of uniform channel mesopores,has been *** channel size can be variedfrom approximately 1.5 nm to greater than 10 nm by choosing different surfactants,auxiliarychemicals(1,3,5-trimethylbenzene)in the reactant,and by changing the reaction *** wall thickness of this kind of molecular sieve is in the range of 0.3 to 1.3 nm esti-

关键词： MCM-41 surface modification adsorption isotherm IR 29Si MAS NMR.