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基于图像处理的裂缝量化分析

化工自动化及仪表 2024年第2期51卷 173-180,337页

作者：许守春许向阳冯宇恒北京理工大学自动化学院

对裂纹量化技术进行了研究,从而获取对应裂缝的长度、宽度信息。针对长度特征的量化,分析现有细化算法提取裂缝骨架的不足,提出新的删除模板与保留模板,通过模板匹配的方式消除裂纹骨架中的冗余像素,并设置合理的长度阈值消除骨架中的... 详细信息

对裂纹量化技术进行了研究,从而获取对应裂缝的长度、宽度信息。针对长度特征的量化,分析现有细化算法提取裂缝骨架的不足,提出新的删除模板与保留模板,通过模板匹配的方式消除裂纹骨架中的冗余像素,并设置合理的长度阈值消除骨架中的冗余骨刺结构,优化骨架的提取,进而获取精确的裂缝长度信息。针对裂缝宽度特征的量化,根据裂纹走向,优化最近距离法,减少计算裂缝宽度的迭代次数,提高量化效率。同时,为了获取更精确的裂缝宽度信息,结合裂缝特征和提取的骨架,采用骨架法向法获取像素级精度的裂缝宽度信息。

关键词：裂缝量化骨架提取最近距离法骨架法向法安全评估

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青年亚文化视域下“孔乙己文学”现象探赜

西安建筑科技大学学报（社会科学版） 2024年第2期43卷 85-91页

作者：朱雅丽徐向阳陕西理工大学人文学院陕西汉中723001

“孔乙己文学”是当下青年亚文化的一个新表征,其诞生直观反映了青年群体的就业困境和对主流文化的抵抗色彩,深层折射出青年群体处于社会加速漩涡的焦虑。娱乐性、碎片化、聚集性和中心化构成了“孔乙己文学”的鲜明特征。在主流文化的... 详细信息

“孔乙己文学”是当下青年亚文化的一个新表征,其诞生直观反映了青年群体的就业困境和对主流文化的抵抗色彩,深层折射出青年群体处于社会加速漩涡的焦虑。娱乐性、碎片化、聚集性和中心化构成了“孔乙己文学”的鲜明特征。在主流文化的引导和青年文化的积极建构下,“孔乙己文学”逐渐被收编,但是其聚焦了青年群体的社会心态,观照了青年群体的文化生态,暴露出青年文化存在的一些问题。因此剖析“孔乙己文学”的诞生逻辑、明晰其特征并对其现象进行反思疏导,对于社会文化尤其是青年文化的建构具有重要意义。

关键词：青年亚文化孔乙己文学青年群体主流文化

Metallographic sample prepared by ion beam etching

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中国有色金属学会会刊：英文版 2004年第z1期14卷 282-285页

作者： xu xiang-yang ZHANG Kun HAN Jian-min CHEN Guang-nan Institute of Materials Science & Engineering Beijing Jiaotong University Beijing 100044 China Institute of Mechanics Chinese Academy of Sciences Beijing 100080 China Institute of Mechanics Chinese Academy of Sciences Beijing 100080 China Institute of Materials Science & Engineering Beijing Jiaotong University Beijing 100044 China

Ion beam etching technique was used to reveal the metallograhpic microstructure and interface morphology of electroplating chromium coating, in particular, whose substrate surface layer was treated in advance by laser quenching. Chemical etchings were also conducted for comparison. The reveal microstructures were observed and analyzed by scanning electron microscopy. The results show that ion beam etching can reveal well the whole microstructures of composite coating-substrate materials.

关键词： ion beam etching metallography microstructure electroplating chromium

Design hardware calculator in PWM peripherals of nios Ⅱ with verilog HDL

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重庆邮电大学学报（自然科学版） 2009年第2期21卷 296-299页

作者： xu yang xiang Min College of Automation Chongqing University of Posts and Telecommunication Chongqing 400065 P. R. China

The Plus Width Module (PWM) in microprocessors is commonly used in motor control field. If the ordinary PWM peripherals output PWM waveform, the software must calculate the period and duty cycle number based on the microprocessor’s system clock cycle first, and then write them into the registers. As all known, the microprocessor without hardware calculator consume very long time in multiplication and division. In order to reduce the CPU’s running time, a calculation hardware unit was designed to calculate the waveform parameters. The software only need to write the period (Hz units) to the period register and the duty cycle (% units)to its register. This hardware unit was designed with Verilog HDL and running in the Nios Ⅱ system successfully.

关键词： Verilog PWM波形 HDL语言硬件设计计算机外设微处理器计算单位

Analysis of Genetic Diversity in Cultivated and Wild Tomato Varieties in Chinese Market by RAPD and SSR

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Agricultural Sciences in China 2010年第10期9卷 1430-1437页

作者： MENG Fan-juan xu xiang-yang HUANG Feng-lan LI Jing-fu College of Life Science University of Northeast Forestry Harbin 150040 P.R.China College of Horticulture Northeast Agricultural University Harbin 150030 P.R.China College of Life Science Inner Mongolia University for Nationalities Tongliao 028000 P.R. China

RAPD and SSR were applied to assess genetic diversity in 61 tomato varieties from different species （Solanum lycopersicum L., hirsutum. Humb L., pimpinellifolium Miller L., chilense Dun. L., chmielenskii L., peruvianum Miller L., parvuflorum Miller L.）. 2 062 and 869 clear fragments were amplified by RAPD and SSR, respectively. On the other hand, more polymorphic products were found by SSR as compared to RAPD, i.e., 100 and 43.84%, respectively. In addition, a higher value of the average similarity coefficient and lower PIC value were reflected in RAPD （0.79, 0.407） compared to SSR （0.56, 0.687）. It can be inferred that SSR was a higher effective marker than RAPD to assess genetic diversity in tomato accessions. Similarly, the genetic base of tomato varieties in Chinese market was narrow. It is suggested that wild tomato varieties should be used to enrich the genetic base of the cultivated tomato varieties.

关键词： tomato genetic diversity RAPD SSR

乳腺MRI、超声以及X线三者联合在乳腺疾病诊断及乳腺癌术式选择中的作用

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中国CT和MRI杂志 2024年第4期22卷 76-79页

作者：李莹徐向阳周瑞程明强华中科技大学同济医学院附属梨园医院放射科湖北武汉430077 武汉大学中南医院甲状腺乳腺外科湖北武汉430062 安陆市第二人民医院外科湖北安陆432600

目的探讨乳腺MRI、超声及乳腺X线在乳腺疾病诊断及乳腺癌手术方式选择中的临床应用价值。方法2019年1月至2020年1月入院的乳腺疾病患者作为研究对象,130例乳腺疾病患者术前均行乳腺MRI、超声及乳腺X线评估乳腺病变,127例乳腺癌患者同时... 详细信息

目的探讨乳腺MRI、超声及乳腺X线在乳腺疾病诊断及乳腺癌手术方式选择中的临床应用价值。方法2019年1月至2020年1月入院的乳腺疾病患者作为研究对象,130例乳腺疾病患者术前均行乳腺MRI、超声及乳腺X线评估乳腺病变,127例乳腺癌患者同时行乳腺MRI及乳腺超声,以评估腋窝淋巴结,进一步确定手术方式。结果三项检查联合运用在乳腺疾病诊断中的敏感性、特异性以及准确性分别为98.51%、98.41%及98.46%。在诊断乳腺结节敏感性方面,三项联合诊断虽高于单用超声、X线及MRI,但统计无显著性差异;而在特异性方面,三项联合诊断高于单用超声及X线,统计有显著性差异;MRI检查的敏感性、特异性和准确性均高于超声及X线检查,分别为97.01%、90.48%和93.85%。超声及MRI二者联合诊断对腋窝淋巴结的敏感性,特异性和准确性分别为94.00%,97.40%及96.06%。二者联合诊断的敏感性、特异性、准确性同单项相比,无统计学差异,说明超声和MRI评估腋窝淋巴结都有一定的优势。结论乳腺MRI、超声和乳腺X线三项检查联合在对乳腺疾病的诊断和腋窝淋巴结转移的评估有较高的准确性,三项检查各有优缺点,适当完美组合有助于手术方法的选择。

关键词：乳腺X线彩色多普勒超声 MRI 保乳

椎体支架系统应用于经皮椎体后凸成形术治疗骨质疏松性椎体压缩性骨折的疗效及对伤椎畸形的矫正效果分析

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中国现代药物应用 2024年第4期18卷 48-51页

作者：徐响阳沈晓涛周祖艳东莞康华医院 523000

目的探讨椎体支架(VBS)系统应用于经皮椎体后凸成形术(PKP)治疗骨质疏松性椎体压缩性骨折(OVCF)的疗效及对伤椎畸形的矫正效果。方法100例OVCF患者,随机分为常规组和实验组,每组50例。常规组接受传统PKP治疗,实验组PKP术中应用VBS系统... 详细信息

目的探讨椎体支架(VBS)系统应用于经皮椎体后凸成形术(PKP)治疗骨质疏松性椎体压缩性骨折(OVCF)的疗效及对伤椎畸形的矫正效果。方法100例OVCF患者,随机分为常规组和实验组,每组50例。常规组接受传统PKP治疗,实验组PKP术中应用VBS系统。比较两组患者手术时间、术中出血量、透视时间、球囊压力、骨水泥注入量、骨水泥渗漏情况、住院时间、住院费用以及不同时间的视觉模拟评分法(VAS)评分、Oswestry功能障碍指数(ODI)、BECK指数、伤椎前缘高度、伤椎中部高度、伤椎前缘高度比、伤椎Cobb角、局部Cobb角。结果两组患者术后1个月和末次随访的VAS评分、ODI评分、BECK指数、伤椎前缘高度、伤椎中部高度、伤椎前缘高度比、局部Cobb角均优于术前,实验组患者术后1个月和末次随访的伤椎Cobb角优于术前(P<0.05);实验组手术时间(63.17±3.85)min、透视时间(45.46±2.92)min长于常规组的(47.43±2.54)、(36.19±1.81)min,球囊压力(219.47±10.83)psi高于常规组的(193.81±4.55)psi,骨水泥注入量(9.54±1.31)ml多于常规组的(7.57±0.95)ml,骨水泥渗漏率2.0%低于常规组的20.0%,住院费用(53456.46±1357.22)元高于常规组的(39067.59±3566.61)元,且术后1个月伤椎Cobb角(7.44±0.81)°、末次随访伤椎Cobb角(8.34±0.76)°均小于常规组的(11.47±0.45)、(12.49±0.42)°,差异均具有统计学意义(P<0.05)。结论两种术式均能使OVCF患者疼痛得到明显改善,但PKP术中应用VBS系统可使伤椎畸形得到更好的矫正,并能够明显降低骨水泥渗漏率,但PKP术中应用VBS术中透视时间、手术时间更长。

关键词：骨质疏松性椎体压缩性骨折腰椎胸椎经皮椎体后凸成形术椎体支架系统伤椎畸形

Genome-wide identification and expression analysis of GDSL esterase/lipase genes in tomato

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Journal of Integrative Agriculture 2022年第2期21卷 389-406页

作者： SUN Yao-guang HE Yu-qing WANG He-xuan JIANG Jing-bin yang Huan-huan xu xiang-yang School of Horticulture and Landscape Architecture Northeast Agricultural UniversityHarbin 150030P.R.China

The GDSL esterase/lipase family contains many functional genes that perform important biological functions in growth and development, morphogenesis, seed oil synthesis, and defense responses in plants. The expression of GDSL esterase/lipase genes can respond to biotic and abiotic stresses. Although GDSL esterase/lipase family genes have been identified and studied in other plants, they have not been identified and their functions remain unclear in tomato. This study is the first to identify 80 GDSL esterase/lipase family genes in tomato, which were named SlGELP1–80. These genes were mapped to their positions on the chromosomes and their physical and chemical properties, gene structure, phylogenetic relationships, collinear relationships, and cis-acting elements were analyzed. The spatiotemporal expression characteristics of the Sl GELP genes in tomato were diverse. In addition, RNA-seq analysis indicated that the expression patterns of the SlGELP genes in tomato differed before and after inoculation with Stemphylium lycopersici. qRT-PCR was used to analyze the expression of five Sl GELP genes after treatments with S. lycopersici, salicylic acid and jasmonic acid. Finally, this study was the first to identify and analyze GDSL esterase/lipase family genes in tomato via bioinformatics approaches, and these findings provide new insights for improving the study of plant disease resistance.

关键词： GDSL esterase/lipase gene family identification plant disease resistance gray leaf spot Solanum lycopersicum

Resolving the geometric structure of trastuzumab by mobility capillary electrophoresis and native mass spectrometry

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Chinese Chemical Letters 2024年第3期35卷 221-225页

作者： Wenjing Zhang Jie Hong Lei yang Zuqiang xu Yu xiang Wei xu School of Life Science Beijing Institute of TechnologyBeijing 100081China

Available online Immunoglobulins G(IgGs)are Y-shaped globular proteins,however,their high flexibility and heterogeneity pose great challenges to their structure and conformation *** structure of IgG closely correlates to its biofunctions,such as the antibody escape of human immunodeficiency virus(HIV)could attribute to the distance mismatch between the ends of two Fab arms(antigen-binding sites)and envelope glycoprotein spikes on virion ***,we report the first use of mobility capillary electrophoresis(MCE)and native mass spectrometry(nMS)to resolve the internal geometric structure and conformation of an IgG(trastuzumab)in solution *** proteolysis,the ellipsoid dimensions of IgG and its subunits were measured by MCE-nMS *** was then reconstructed,in which the sizes and relative positions of these three subunits in three-dimensional space were *** was found that the two Fab arms have an angle of~102.1°and a distance of~11.0 nm between the two antigen-binding sites under native condition,and the Fc arm was tilted~16.0°towards one of the Fab *** was not on the plane of Fab-Fab,but has an angle of no larger than 103.1°.Under acidic environment(pH 3.0),each subunit of the IgG would unfold into larger dimensions,and the angles between these subunits also *** great potential for tumor imaging and therapy,the structure of F(ab')_(2)fragments was also measured and validated by molecular dynamic *** was found that the electrostatic force among these three subunits and steric hindrance stemming from Fc help maintaining the angle between two Fab arms.

关键词： Native mass spectrometry Mobility capillary electrophoresis Trastuzumab Protein structure Geometric structure