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Improvement of impact properties of Al-Si-Mg alloy via solution treatment and joint modification with Sr and La

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Rare Metals 2024年第7期43卷 3301-3313页

作者： Xiong-Ling Zheng Shao-Xiang Li Jia-Le Ma Qing-Yan xu hai-Dong Zhao Zhi-Qiang Han Key Laboratory for Advanced Materials Processing Technology Ministry of EducationSchool of Materials Science and EngineeringTsinghua UniversityBeijing 100084China National Engineering Research Center of Near-Net Shape Forming for Metallic Materials South China University of TechnologyGuangzhou 510641China

An effort to obtain superior impact properties for Al-7Si-0.35 Mg alloy is presented,where modification with 0.02 wt% Sr and 0.1 wt% La as well as solution treatment was jointly *** samples were solution treated at 535℃ for 15 min to 12 *** microstructure,fracture mechanism,and their correlation with the impact properties of the alloy were studied in detail mainly through optical microscopy(OM),scanning electron microscopy(SEM) and oscillography impact *** results show that the addition of Sr and La refined the eutectic Si particles significantly from~ 2.05 μm(modified with Sr alone) to~ 0.75 μm in as-cast microstructure,leading to a very homogeneous distribution of spheroidized Si particles in the alloy solution treated at 535℃ for 8 *** alloy exhibits excellent impact toughness up to 75 J·cm^(-2),which is much higher than the maximum impact toughness of the alloys modified by Sr alone(~ 46 J·cm^(-2)).The major reason for this remarkable increase in the impact property is the dramatic increase in crack initiation *** dispersoid-free zones(DFZs)near the eutectic regions mainly consist of the ductile Al-matrix,which exhibits excellent *** ductile Al-matrix of the DFZs hinders the crack propagation,resulting in a significant increase in crack propagation energy.

关键词： Aluminum alloys Modification Solution treatment Microstructure Impact properties Fracture mechanism

Status quo and factors of depression and anxiety in patients with non-muscle invasive bladder cancer after plasma electrocision

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World Journal of Psychiatry 2024年第6期14卷 822-828页

作者： Bing Lu Meng Ding Hong-Bo xu Chun-yin Yan Department of Urology Suzhou Dushu Lake HospitalSuzhou 215000Jiangsu ProvinceChina Department of Urology The First Affiliated Hospital of Soochow UniversitySuzhou 215000Jiangsu ProvinceChina

BACKGROUND Bladder cancer is a type of cancer with a high incidence in *** electrosurgery(PES)is often used in the treatment of bladder *** complications often cause depression and anxiety in patients after *** To investigate the current state of depression and anxiety after PES in patients with non-muscle-invasive bladder cancer and analyze the factors affecting *** A retrospective study was conducted to compare the baseline data of patients by collecting their medical history and grouping them according to their mental status into negative and normal *** regression analysis was used to explore the risk factors affecting the occurrence of anxiety and depression after surgery in patients with bladder *** Comparative analyses of baseline differences showed that the patients in the negative and normal groups differed in terms of their first surgery,economic status,educational level,and marital status.A logistic regression analysis showed that it affected the occurrence of anxiety in patients with bladder cancer,and the results showed that whether the risk factors were whether or not it was the first surgery,monthly income between 3000 and 3000-6000,secondary or junior high school education level,single,divorced,and widowed *** The risk factors affecting the onset of anxiety and depression in bladder cancer patients after PES are the number of surgeries,economic status,level of education,and marital *** study provides a reference for the clinical treatment and prognosis of bladder cancer patients in the future.

关键词： Bladder cancer Anxiety Depression Analysis of influencing factors Plasma electrocision

Fracture sealing performance of granular lost circulation materials at elevated temperature:A theoretical and coupled CFD-DEM simulation study

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Petroleum Science 2024年第1期21卷 567-581页

作者： Chong Lin Qi-Cong xu Lie-Xiang Han Gao Li hai He Hong-Ling Zhou Ji-Ping She CCDC Drilling&Production Technology Research Institute Guanghan618300SichuanChina State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation Southwest Petroleum UniversityChengdu610500SichuanChina College of Materials Science and Engineering Chongqing UniversityChongqing400044China State Key Lab of Oil and Gas Reservoir Geology and Exploitation(Chengdu University of Technology) Chengdu610059SichuanChina College of Energy Chengdu University of TechnologyChengdu610059SichuanChina

Lost circulation is a common downhole problem of drilling in geothermal and high-temperature,high-pressure(HTHP)*** circulation material(LCM)is a regular preventive and remedial measure for lost ***,conventional LCMs seem ineffective in high-temperature *** may be due to the changes in the mechanical properties of LCMs and their sealing performance under high-temperature *** understand how high temperature affects the fracture sealing performance of LCMs,we developed a coupled computational fluid dynamics-discrete element method(CFD-DEM)model to simulate the behavior of granular LCMs in *** summarized the literature on the effects of high temperature on the mechanical properties of LCMs and the rheological properties of drilling *** conducted sensitivity analyses to investigate how changing LCM slurry properties affected the fracture sealing efficiency at increasing *** results show that high temperature reduces the size,strength,and friction coefficient of LCMs as well as the drilling fluid ***,softer,and less frictional LCM particles have lower bridging probability and slower bridging *** particles tend to form dual-particle bridges rather than single-particle *** result in a deeper,tighter,but unstable sealing *** drilling fluid viscosity leads to faster and shallower sealing zones.

关键词： Geothermal well drilling HTHP formationLost circulation material CFD-DEM Fracture sealing

Federated Learning Model for Auto Insurance Rate Setting Based on Tweedie Distribution

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工程与科学中的计算机建模(英文) 2024年第1期138卷 827-843页

作者： Tao yin Changgen Peng Weijie Tan Dequan xu Hanlin Tang State Key Laboratory of Public Big Data Guizhou UniversityGuiyang550025China Guizhou Big Data Academy Guizhou UniversityGuiyang550025China Key Laboratory of Advanced Manufacturing Technology Ministry of EducationGuizhou UniversityGuiyang550025China College of Computer Science and Technology Guizhou UniversityGuiyang550025China ChinaDataPay Company Guiyang550025China

In the assessment of car insurance claims,the claim rate for car insurance presents a highly skewed probability distribution,which is typically modeled using Tweedie *** traditional approach to obtaining the Tweedie regression model involves training on a centralized dataset,when the data is provided by multiple parties,training a privacy-preserving Tweedie regression model without exchanging raw data becomes a *** address this issue,this study introduces a novel vertical federated learning-based Tweedie regression algorithm for multi-party auto insurance rate setting in data *** algorithm can keep sensitive data locally and uses privacy-preserving techniques to achieve intersection operations between the two parties holding the *** determining which entities are shared,the participants train the model locally using the shared entity data to obtain the local generalized linear model intermediate *** homomorphic encryption algorithms are introduced to interact with and update the model intermediate parameters to collaboratively complete the joint training of the car insurance rate-setting *** tests on two publicly available datasets show that the proposed federated Tweedie regression algorithm can effectively generate Tweedie regression models that leverage the value of data fromboth partieswithout exchanging *** assessment results of the scheme approach those of the Tweedie regressionmodel learned fromcentralized data,and outperformthe Tweedie regressionmodel learned independently by a single party.

关键词： Rate setting Tweedie distribution generalized linear models federated learning homomorphic encryption

Features and formulae of sediment incipient motion in vegetated flow environment

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Journal of Hydrodynamics 2024年第2期36卷 331-339页

作者： Yu-xuan xu Wei-jie Wang Shi-bao Zhang Han-qing Zhao xue-kai Chen hai-ping Zhang School of Water Conservancy North China University of Water Resources and Electric PowerZhengzhou450045China State Key Laboratory of Simulation and Regulation of Water Cycle in River Basin China Institute of Water Resources and Hydropower ResearchBeijing100038China China Three Gorges Corporation Wuhan430010China

Aquatic vegetation is a vital component of natural river ecosystems,playing a crucial role in maintaining ecological balance,providing habitat and improving water ***,the presence of vegetation results in increased resistance in vegetated channels compared with non-vegetated channels,rendering traditional sediment movement predictions inadequate for the ***,the concept of a vegetation influence factor,denoted by CDah,has been proposed by previous researchers to represent the effect of vegetation on sediment movement in *** this study,we focus on exploring the vegetation resistance coefficient(CD)among the vegetation influence factors,evaluating two different calculation methods for vegetation resistance coefficient,and presenting two expressions through genetic algorithm analysis to predict the incipient flow velocity of sediment in vegetated *** predicted values from the new formulae show excellent agreement with measured data,highlighting the high accuracy of the proposed methods in predicting the incipient flow velocity of *** results provide a solid theoretical basis for understanding the influence of aquatic vegetation on sediment particle movement.

关键词： Vegetation flow vegetation resistance coefficient genetic algorithm sediment initiation

The Risk Role of Defeat on the Mental Health of College Students:A Moderated Mediation Effect of Academic Stress and Interpersonal Relationships

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International Journal of Mental Health Promotion 2024年第9期26卷 731-744页

作者： Ruiyang Han Tingting xu yin Shi Wuyi Liu School of Public Health Shandong Second Medical UniversityWeifang261053China Faculty of Education Beijing Normal UniversityBeijing100875China School of Clinical Medicine Shandong Second Medical UniversityWeifang261053China

Background:College students face significant academic and physiological changes,making them more susceptible to psychological issues such as depression,self-injury,and suicidal *** of defeat can exacerbate these risks by increasing academic ***,interpersonal relationships can moderate the impact of academic stress on students’mental *** the presage–process–product model,this study aims to empirically investigate how feelings of defeat influence depression,self-injury,and suicidal ideation among college ***,it explores the mediating role of academic stress and the moderating role of various types of interpersonal ***:A total of 1612 college students(750 females,862 males,mean age=19.64±0.62 years)were recruited through cluster *** were collected via offline questionnaires administered by a trained psychology teacher and a postgraduate student,ensuring high reliability with two examiners per *** profile analysis(LPA)was used to examine the impact of defeat on mental health outcomes,while mediation analysis was conducted to assess the roles of academic stress and interpersonal ***:*** is identified as a significant risk factor for mental health issues among college students;*** distinct patterns of interpersonal relationships were identified:the interpersonal-relationship risk group,the father–child-relationship high-risk group,the general interpersonal-relationship group,and the superior interpersonal-relationship group;*** stress partially mediates the relationship between defeat and mental health issues such as depression,self-injury,and suicidal ideation;*** interpersonal relationship models moderate the impact of academic stress on depression and suicidal ***:Defeat is a significant risk factor for mental health problems in college *** stress partially mediates the negative impact of defeat on mental he

关键词： Student mental health defeat academic stress interpersonal relationships mediation test

Building imaginary-time thermal field theory with artificial neural networks

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Chinese Physics C 2024年第10期48卷 23-30页

作者： Tian xu Lingxiao Wang Lianyi He Kai Zhou yin Jiang Physics Department Beihang University37 Xueyuan RdBeijing 100191China Shanghai Research Center for Theoretical Nuclear Physics National Natural Science Foundation of ChinaFudan UniversityShanghai 200438China Department of Physics Tsinghua UniversityBeijing 100084China School of Science and Engineering The Chinese University of Hong KongShenzhenShenzhen 518172China Frankfurt Institute for Advanced Studies Ruth-Moufang-Str.160438 Frankfurt am MainGermany

In this paper,we introduce a novel approach in quantum field theories to estimate actions using artificial neural networks(ANNs).The actions are estimated by learning system configurations governed by the Boltzmann factor,e^(-s),at different temperatures within the imaginary time formalism of thermal field ***,we focus on the 0+1 dimensional quantum field with kink/anti-kink configurations to demonstrate the feasibility of the ***-mixture autoregressive networks(CANs)enable the construction of accurate effective actions with tractable probability density *** numerical results demonstrate that this methodology not only facilitates the construction of effective actions at specified temperatures but also adeptly estimates the action at intermediate temperatures using data from both lower and higher temperature *** capability is especially valuable for detailed exploration of phase diagrams.

关键词： artificial neural network imaginary-time thermal field theory effective model probability estimation

RPRD1B/CREPT facilitates the progression of diffuse large B-cell lymphoma by inhibiting apoptosis through the NF-κB signaling pathway

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Asian Pacific Journal of Tropical Biomedicine 2024年第7期14卷 307-318页

作者： Lu xu Zhi-Hao Xie Jun Li Shi Tao Fang-Li Ren yin-yin Wang Zhi-Jie Chang Xin-Bao Hao Department of Hematology The First Affiliated Hospital of Hainan Medical UniversityHaikou570102China State Key Laboratory of Membrane Biology School of MedicineTsinghua UniversityBeijing 100084China Heya Beijing Med-Biotech Inc. Beijing 100084China Department of Hematology Roswell Park Comprehensive Cancer CenterNY 14263USA

Objective:To investigate the role of RPRD1B in the progression of diffuse large B-cell lymphoma(DLBCL)and its potential as a therapeutic ***:This study analyzed RPRD1B expression in DLBCL and normal tissues using public databases and assessed its prognostic impact through survival *** vitro and in vivo experiments were conducted to explore the mechanisms by which RPRD1B influences tumor growth and ***:RPRD1B expression was significantly elevated in DLBCL compared to normal tissues and was associated with poor *** vitro and in vivo experiments demonstrated that RPRD1B promoted lymphoma cell proliferation and inhibited apoptosis through the NF-κB signaling ***:RPRD1B plays a critical role in the progression of DLBCL by modulating apoptosis and cellular *** RPRD1B may offer a novel therapeutic strategy for DLBCL,suggesting its potential as a prognostic marker and therapeutic target in hematological malignancies.

关键词： RPRD1B RNAPⅡ Diffuse large B-cell lymphoma NF-κB Apoptosis

Current and Potential Roles of Ferroptosis in Bladder Cancer

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Current Medical Science 2024年第1期44卷 51-63页

作者： Wen-xin AN Radheshyam Gupta Kun Zhai Ya-ru WANG Wan-hai xu Yan CUI Department of Urology Harbin Medical University Cancer HospitalHarbin 150081China Department of Internal Medical Oncology Harbin Medical University Cancer HospitalHarbin 150081China

Ferroptosis,a type of regulated cell death driven by iron-dependent lipid peroxidation,is mainly initiated by extramitochondrial lipid peroxidation due to the accumulation of iron-dependent reactive oxygen *** is a prevalent and primitive form of cell *** cellular metabolic processes regulate ferroptosis,including redox homeostasis,iron regulation,mitochondrial activity,amino acid metabolism,lipid metabolism,and various disease-related signaling *** plays a pivotal role in cancer therapy,particularly in the eradication of aggressive malignancies resistant to conventional *** studies have explored the connection between ferroptosis and bladder cancer,focusing on its incidence and treatment *** biomolecules and tumor-associated signaling pathways,such as p53,heat shock protein 1,nuclear receptor coactivator 4,RAS-RAF-MEK,phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin,and the Hippo-tafazzin signaling system,exert a moderating influence on ferroptosis in bladder *** inducers,including erastin,artemisinin,conjugated polymer nanoparticles,and quinazolinyl-arylurea derivatives,hold promise for enhancing the effectiveness of conventional anticancer medications in bladder cancer *** conventional therapeutic drugs and treatment methods related to ferroptosis offers a promising approach for the treatment of bladder *** this review,we analyze the research on ferroptosis to augment the efficacy of bladder cancer treatment.

关键词： ferroptosis bladder cancer ferroptosis-associated tumor signaling pathway ferroptosis inducer