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Chinese Medical Journal 2012年第19期125卷 3581-3583页

作者： LI Yang LIU Nai-feng GU Zhong-ze CHEN Yong LU Jun FENG Yi MA Gen-shan SHEN Cheng-xing department of Cardiology Zhongda Hospital Southeast University Nanjing Jiangsu 210009 China School of Biological Science and Medical Engineering. Southeast university Naniin~. Jian..su 210096. China department of Cardiology Xinhua Hospital Shanghai Jiao Tong University School of Medicine Shanghai 200092. China

Coronary artery disease （CAD） is the leading cause of cardiovascular death in the Chinese *** angiography is the golden standard for the diagnosis of CAD and coronary tortuosity （CT） is a common coronary angiographic finding, however, little work has been done on clinical manifestation and significance of CT. It was hypothesized that CT may be associated with angina pectoris and abnormal exercise stress test in patients without CAD, but weather CT can lead to cardiac ischemia has not yet been clarified. The purpose of this study was to determine the impact of CT on myocardial perfusion detects.

关键词： coronary tortuosity cardiac ischemia myocardial perfusion defects coronary pressure

基于稀疏特征挑选和概率线性判别分析的表情识别研究

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电子学报 2018年第7期46卷 1710-1718页

作者：张瑞蒋晨之苏剑波上海交通大学自动化系系统控制与信息处理教育部重点实验室上海200240

提出一种基于稀疏特征挑选(Sparse selection)和概率线性判别分析(Probabilistic linear discriminant analysis)的表情识别方法 SS-PLDA.该方法由两部分构成:第一部分是使用稀疏的方法挑选出人脸与表情相关的区域,构造表情的完备特征集... 详细信息

提出一种基于稀疏特征挑选(Sparse selection)和概率线性判别分析(Probabilistic linear discriminant analysis)的表情识别方法 SS-PLDA.该方法由两部分构成:第一部分是使用稀疏的方法挑选出人脸与表情相关的区域,构造表情的完备特征集;第二部分是针对构造的表情完备特征集里仍含有一些其他信息,运用概率线性判别分析实现表情特征与干扰信息的分离,学习出一个只含有表情信息的子空间,最后基于该表情子空间进行表情识别分析.通过在CK+和JAFFE这两个数据库上面的实验,证实了基于稀疏特征挑选的方法可以得到识别性能的改善,且先使用特征挑选再对所挑选结果应用概率线性判别分析可以达到更好的提升效果.

关键词：人脸表情识别稀疏特征挑选子空间学习

Darbepoetin alfa injection versus epoetin alfa injection for treating anemia of Chinese hemodialysis patients with chronic kidney failure:A randomized,open-label,parallel-group,non-inferiority Phase III trail

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Chronic Diseases and Translational Medicine 2022年第1期8卷 59-70页

作者： Nan Chen Changying xing Jianying Niu Bicheng Liu Junzhou Fu Jiuyang Zhao Zhaohui Ni Mei Wang Wenhu Liu Jinghong Zhao Ling Zhong Xiongfei Wu Wenge Li Yuqing Chen Wei Shi Jianghua Chen Aiping Yin Ping Fu Rong Wang Gengru Jiang Fanfan Hou Guohua Ding Jing Chen Gang Xu Yuichiro Kondo Yuliang su Changlin Mei department of Nephrology Ruijin Hospital Shanghai Jiaotong University School of MedicineShanghai 200025China department of Nephrology Jiangsu Provincial HospitalNanjingJiangsu 210036China department of Nephrology Shanghai Fifth People's HospitalFudan UniversityShanghai 200240China department of Nephrology Zhongda Hospital Southeast UniversityNanjingJiangsu 210009China department of Nephrology Guangzhou First People's HospitalGuangzhouGuangdong 510180China department of Nephrology The Second Hospital of Dalian Medical UniversityDalianLiaoning 116027China department of Nephrology Renji Hospital Shanghai Jiaotong University School of MedicineShanghai 200001China department of Nephrology Peking University People's HospitalBeijing 100044China department of Nephrology Beijing Friendship HospitalCapital Medical UniversityBeijing 100050China department of Nephrology Xinqiao Hospital of Army Medical UniversityChongqing 400037China department of Nephrology The Second Affiliated Hospital of Chongqing Medical UniversityChongqing 400010China department of Nephrology Southwest Hospital of Army Medical UniversityChongqing 400039China department of Nephrology China-Japan Friendship HospitalBeijing 100029China department of Nephrology Peking University First HospitalBeijing 100034China department of Nephrology Guangdong Provincial People's HospitalGuangzhouGuangdong 510080China department of Nephrology The First Affiliated HospitalZhejiang University School of MedicineHangzhouZhejiang 310003China department of Nephrology First Affiliated Hospital of Xi'an Jiaotong UniversityXi'anShaanxi 710061China department of Nephrology West China HospitalSichuan UniversityChengduSichuan 610041China department of Nephrology Shandong Provincial HospitalJinanShandong 250021China department of Nephrology Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai 200092China department of Nephrology Nanfang Hospital Southern Medical UniversityGuangzhouGuangdong 5105

Background:Erythropoietin is a glycoprotein that mainly regulates *** patients with chronic renal failure with anemia,darbepoetin alfa can stimulate erythropoiesis,correct anemia,and maintain hemoglobin *** study was designed to demonstrate the efficacy and safety of darbepoetin alfa injections as being not inferior to epoetin alfa injections(Recombinant Human Erythropoietin injection,rHuEPO)when maintaining hemoglobin(Hb)levels within the target range(10.0-12.0 g/dL)for the treatment of renal ***:Ninety-five patients were enrolled in this study from April 15,2013 to April 10,2014 at 25 *** this study,patients(n=95)aged 18-70 years were randomized into a once per week intravenous darbepoetin alfa group(n=56)and a twice or three times per week intravenous epoetin alfa group(n=39)for 28 weeks,who had anemia with hemoglobin levels between 6 g/dL and 10 g/dL due to chronic kidney disease(CKD)and were undergoing hemodialysis or hemofiltration with ESA-naive(erythropoiesis stimulating agent-naive).The primary efficacy profile was the mean Hb level(the non-inferiority margin was-1.0 g/dL,week 21-28);the secondary efficacy profiles were the Hb increase rate(week 0-4),the target Hb achievement cumulative rate and time,the change trends of the Hb levels,and the target Hb maintenance *** events(AEs)were observed and compared,and the efficacy and safety were analyzed between the two treatment ***,the frequencies of dose adjustments between the darbepoetin alfa and epoetin alfa groups were compared during the treatment ***?software version 9.2 was used to perform all statistical *** statistics were used for all efficacy,safety,and demographic variable analyses,including for the primary efficacy ***:The mean Hb level was 11.3 g/dL in the darbepoetin alfa group and 10.7 g/dL in the epoetin alfa group,respectively;the difference of the lower limits of the 95%confidence intervals(C

关键词： anemia chronic renal failure darbepoetin alfa hemodialysis recombinant human erythropoietin

Expert consensus on clinical standardized application of high-flow nasal cannula oxygen therapy in adults

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Chinese Medical Journal 2020年第11期133卷 1322-1324页

作者： Jian-Qiao Xu Long-Xiang su Peng Yan xing-Shuo Hu Ruo-Xuan Wen Kun Xiao Hong-Jun Gu Jin-Gen Xia Bing sun Qing-Tao Zhou Yu-Chao Dong Jia-Lin Liu Pin-Hua Pan Hong Luo Qi Li Li-Qiang Song Si-Cheng Xu Yan-Ming Li Dao-Xin Wang Dan Li Qing-Yuan Zhan Li-Xin Xie 无 Departm ent of Pulmonary&Critical Care Medicine Chinese People Liberation Army(PLA)General HospitalBeijing 100853China department of Critical Care Medicine Peking Union Medical College HospitalBeijing 100005China department of Pulmonary&Critical Care Medicine China and Japan Friendship HospitalBeijing 100029China department of Pulmonary&Critical Care Medicine Beijing Chaoyang Hospital affiliated to Capital Medical UniversityBeijing 100020China department of Pulmonary&Critical Care Medicine Peking University Third HospitalBeijing 100191China department of Respiratory Medicine Changhai HospitalShanghai 200433China department of Respiratory Medicine Ruijin Hospital Affiliated to the Shanghai Jiao Tong University Medical SchoolShanghai 200025China department of Respiratory Medicine XiangYa HospitalCentral South UniversityChangshaHunan 410008China department of Pulmonary&Critical Care Medicine XiangYa Second Hospital of Central South UniversityChangshaHunan 410011China department of Pulmonary&Critical Care Medicine Xinqiao Hospital of the Third Military Medical UniversityChongqing 400037China department of Pulmonary&Critical Care Medicine Xijing Hospital of Fourth Military Medical UniversityXi'anShaanxi 710032China department of Respiratory Medicine The First Affiliated Hospital of Xinjiang Medical UniversityUrumqiXinjiang 830000China department of Pulmonary&Critical Care Medicine Beijing HospitalBeijing 100730China department of Respiratory Medicine The Second Affiliated Hospital of Chongqing Medical UniversityChongqing 400010China department of Respiratory Medicine The First Bethune Hospital of Jilin UniversityChangchunJilin 130021China Pulmonary&Critical Care Medicine Group of Chinese Thoracic Society/Pulmonary&Critical Care Medicine Committee of Chinese Association of Chest Physician

High-flow nasal cannula oxygen therapy(HFNC)is a novel respiratory support technology and has been extensively applied in clinics in recent *** therapeutic equipment mainly includes an air-oxygen blender,an active humidifier,a high-flow nasal cannula,and a connecting inspiratory *** provides patients a humidified high-flow gas(8-80 L/min)with relatively stable oxygen concentration(21-100%),temperature(31-37℃)and performs oxygen therapy via a nasal cannula,which is very comfortable.

关键词： flow connecting high

胃癌近端胃切除联合不同抗反流消化道重建方式疗效评估的多中心回顾性研究

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中华外科杂志 2022年第9期60卷 838-845页

作者：杨力吴健章尤俊樊林靖昌庆王权燕速余江臧潞邢加迪胡文庆刘凤林南京医科大学第一附属医院普通外科南京210029 复旦大学附属中山医院普通外科上海200032 厦门大学附属第一医院胃肠肿瘤外科厦门361000 西安交通大学第一附属医院普通外科西安710061 山东省立医院普通外科济南250021 吉林大学第一医院普通外科长春130061 青海大学附属医院胃肠肿瘤外科西宁810001 南方医科大学南方医院普通外科广州510515 上海交通大学医学院附属瑞金医院普通外科上海200025 北京大学肿瘤医院暨北京市肿瘤防治研究所胃肠肿瘤中心北京100143 长治市人民医院普通外科长治046099

目的探讨胃癌近端胃切除后不同抗反流消化道重建方式的临床效果。方法回顾性收集2016年9月至2021年8月在中国11家医疗中心就诊的338例近端胃切除后行抗反流消化道重建的胃癌患者的临床资料,男性273例,女性65例,年龄(63±10)岁(范围:28~9... 详细信息

目的探讨胃癌近端胃切除后不同抗反流消化道重建方式的临床效果。方法回顾性收集2016年9月至2021年8月在中国11家医疗中心就诊的338例近端胃切除后行抗反流消化道重建的胃癌患者的临床资料,男性273例,女性65例,年龄(63±10)岁(范围:28~91岁)。其中管状胃食管吻合159例(管状胃组),空肠双通道重建107例(双通道组),食管胃双肌瓣技术吻合72例(双肌瓣组)。记录手术时间、术后住院时间、术后早期并发症及分级、术后营养状态,根据洛杉矶分级法对术后12个月胃镜下反流性食管炎进行分级,Visick分级标准评估术后生活质量。分别采用方差分析、混合线性模型、Kruskal-Wallis秩和检验、χ^(2)检验和Fisher确切概率法进行多组间比较,两两比较采用Bonferroni法校正。结果双肌瓣组手术时间明显长于管状胃组和双通道组[(352±63)min比(221±66)min,(352±63)min比(234±61)min,P均0.05)。术后12个月双通道组反流性食管炎的发生率为12.9%(4/31),低于双肌瓣组的45.9%(17/37)(χ^(2)=8.63,P=0.003)。双肌瓣组术后Visick 2~4级不适症状的比例为10.4%(7/67),低于管状胃组的34.6%(27/78)(χ^(2)=11.70,P=0.018),但与双通道组的22.2%(8/36)差异无统计学意义(P>0.05)。结论双肌瓣技术手术时间长于管状胃吻合及双通道重建,但术后早期并发症发生率相当。双肌瓣技术更有利于患者术后营养状态和生活质量的改善,其优势相较于管状胃吻合更加明显。双通道重建术后反流性食管炎发生风险低于双肌瓣技术。

关键词：食管胃接合处胃切除术胃食管反流管状胃吻合双通道重建双肌瓣技术

吸烟对急性ST段抬高型心肌梗死急性期心肌损伤及预后的影响

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上海交通大学学报（医学版） 2020年第5期40卷 573-582页

作者：冯泽豪张清柴烨子苏璇孙宝航行刘启明严福华姜萌卜军上海交通大学医学院附属仁济医院心内科上海200127 上海交通大学医学院附属瑞金医院放射科上海200025

目的·结合心脏磁共振技术探讨吸烟对ST段抬高型心肌梗死(ST-segment elevation myocardial infraction,STEMI)患者急性期心肌损伤的影响及长期预后。方法·筛选349名自2012年5月至2017年8月入组的STEMI患者并至少随访2年,随访的主要终... 详细信息

目的·结合心脏磁共振技术探讨吸烟对ST段抬高型心肌梗死(ST-segment elevation myocardial infraction,STEMI)患者急性期心肌损伤的影响及长期预后。方法·筛选349名自2012年5月至2017年8月入组的STEMI患者并至少随访2年,随访的主要终点指标包括全因死亡、再发心肌梗死及卒中,次要终点指标为再发心力衰竭入院。根据患者入组前吸烟状态分为吸烟组及非吸烟组,结合是否出现心肌内出血(intramyocardial hemorrhage,IMH)进一步分析2组患者终点事件发生率的差异。结果·吸烟组共221人,占总样本的63.3%;吸烟组患者的平均发病年龄较非吸烟组提前4.66岁,但住院期间左心室血栓发生率及脑利钠肽水平均低于非吸烟组(P=0.023,P=0.000)。在影像学参数中,2组患者的左心室射血分数差异无统计学意义(P>0.05),但吸烟患者的收缩末期及舒张末期容积指数与非吸烟组患者差异有统计学意义(P=0.019,P=0.007)。吸烟与非吸烟患者的主要终点事件发生率差异无统计学意义(P>0.05),吸烟患者的心力衰竭再入院率低于非吸烟患者,但进一步校正基线差异后2组间心力衰竭发生率差异无统计学意义(P=0.167)。在有IMH的患者中,吸烟对主要终点起到保护作用(HR=0.266,P=0.008)。在无IMH的患者中,非吸烟者的全因死亡及再发心肌梗死预后优于吸烟者(P=0.024)。结论·在STEMI患者中吸烟对长期预后无保护作用;在合并IMH时吸烟对全因死亡、再发心肌梗死及卒中具有一定保护作用,但在无IMH的患者中,吸烟患者预后差于非吸烟者。

关键词：吸烟者矛盾心肌内出血心脏磁共振 ST段抬高型心肌梗死

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计及源荷双边性能指标的市场交易模型

电力自动化设备 2019年第2期39卷 173-180页

作者：索瑞鸿陈杏宋依群严正姚良忠上海交通大学电气工程系电力传输与功率变换控制教育部重点实验室上海200240 中国电力科学研究院北京100192

高比例可再生能源电网内,为促进优质可控电源与可控负荷的发展,提高系统供需平衡的调节能力,考虑电源和负荷响应性能进行电力市场交易模式设计。在电源侧引入机组的调节性能指标;在负荷侧设置负荷聚合商参与市场的场景,并考虑负荷响应... 详细信息

高比例可再生能源电网内,为促进优质可控电源与可控负荷的发展,提高系统供需平衡的调节能力,考虑电源和负荷响应性能进行电力市场交易模式设计。在电源侧引入机组的调节性能指标;在负荷侧设置负荷聚合商参与市场的场景,并考虑负荷响应偏差的随机性进而提出负荷响应性能指标,以区分不同响应特性带来的运行成本差异。为合理协调计及性能指标的源荷双边资源,设计了两阶段的差异化出清机制。以系统总运行成本最小化为目标,构建有负荷聚合商参与的日前市场出清模型。通过算例结果表明,计及源荷双边性能指标的交易模型,可以引导资源的优化配置,降低市场的风险和损失。

关键词：电力市场负荷响应性能高比例可再生能源市场交易模型响应性能

Towards human-like and transhuman perception in AI 2.0:a review

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Frontiers of Information Technology & Electronic Engineering 2017年第1期18卷 58-67页

作者： Yong-hong TIAN Xi-lin CHEN Hong-kai XIONG Hong-liang LI Li-rong DAI Jing CHEN Jun-liang xing Xi-hong WU Wei-min HU Yu HU Tie-jun HUANG Wen GAO School of Electronics Engineering and Computer Science Peking University Institute of Computing Technology Chinese Academy of Sciences department of Electronic Engineering Shanghai Jiao Tong University School of Electronic Engineering University of Electronic Science and Technology of China department of Electronic Engineering and Information Sciences University of Science and Technology of China School of Optoelectronics Beijing Institute of Technology Institute of automation Chinese Academy of Sciences

Perception is the interaction interface between an intelligent system and the real world. Without sophisticated and flexible perceptual capabilities, it is impossible to create advanced artificial intelligence （AI） systems. For the next-generation AI, called ＇AI 2.0＇, one of the most significant features will be that AI is empowered with intelligent perceptual capabilities, which can simulate human brain＇s mechanisms and are likely to surpass human brain in terms of performance. In this paper, we briefly review the state-of-the-art advances across different areas of perception, including visual perception, auditory perception, speech perception, and perceptual information processing and learning engines. On this basis, we envision several R＆D trends in intelligent perception for the forthcoming era of AI 2.0, including：（1） human-like and transhuman active vision; （2） auditory perception and computation in an actual auditory setting; （3） speech perception and computation in a natural interaction setting; （4） autonomous learning of perceptual information; （5） large-scale perceptual information processing and learning platforms; and （6） urban omnidirectional intelligent perception and reasoning engines. We believe these research directions should be highlighted in the future plans for AI 2.0.

关键词： Intelligent perception Active vision Auditory perception Speech perception Autonomous learning

基于深度收缩稀疏自编码网络的飞行员疲劳状态识别

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控制与决策 2018年第12期33卷 2263-2269页

作者：吴奇储银雪陈曦林金星任和上海交通大学自动化系上海200240 上海飞机客户服务有限公司上海200241 南京邮电大学自动化学院南京210023

飞行员的疲劳状态识别具有重要的研究意义和应用价值.针对飞行员疲劳状态识别的复杂性和准确性,提出一种新的基于脑电信号的飞行员疲劳状态识别深度学习模型.在对飞行员的脑电信号进行滤波分解的基础上,提取delta波(0.5～4 Hz)、theta... 详细信息

飞行员的疲劳状态识别具有重要的研究意义和应用价值.针对飞行员疲劳状态识别的复杂性和准确性,提出一种新的基于脑电信号的飞行员疲劳状态识别深度学习模型.在对飞行员的脑电信号进行滤波分解的基础上,提取delta波(0.5～4 Hz)、theta波(5～8 Hz)、alpha波(7～14 Hz)和beta波(14～30 Hz),将其重组信号作为深度收缩稀疏自编码网络-Softmax模型的输入向量,用以对飞行员疲劳状态的识别,所得到的实验结果与深度自编码网络-Softmax模型和传统方法PCA-Softmax模型识别结果进行比较,结果表明所建立的深度学习模型具有很好的分类效果,分类准确率可达91.67%,且学习所得的特征稳定性好,验证了所提模型具有稳定性和重复验证性.

关键词：飞行员疲劳脑电信号深度收缩稀疏自编码网络深度自编码网络 Softmax分类器准确率

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我国转化医学国家重大科技基础设施建设初探

上海交通大学学报（医学版） 2020年第6期40卷 701-706页

作者：李冬凉赖昱臣张薇薇王戬李春红王甦平施琼芸张行陶晔璇上海交通大学医学院学科规划处上海200025

目的·探讨我国转化医学国家重大科技基础设施建设的初步经验,为未来发展提供参考。方法·采用文献分析法,就国内外重大科技基础设施建设的现状、经验和启示进行整理,并通过专家访谈法收集相关意见,总结我国转化医学国家重大科技基础设... 详细信息

目的·探讨我国转化医学国家重大科技基础设施建设的初步经验,为未来发展提供参考。方法·采用文献分析法,就国内外重大科技基础设施建设的现状、经验和启示进行整理,并通过专家访谈法收集相关意见,总结我国转化医学国家重大科技基础设施建设的初步经验。结果·国内外重大科技基础设施建设中值得借鉴的经验与启示主要包括高质量人才队伍建设、仪器设备开放共享、产学研协同、国际合作交流、大设施集群发展、人才培养和科学数据共建共享机制7个方面。我国转化医学重大科技基础设施建设起步较晚,在上述前5个方面已形成了初步经验,在后2个方面尚需探索,且在充分利用依托单位优势、多渠道筹集资金2个方面形成了自身经验。结论·我国转化医学重大科技基础设施建设需结合自身特点并借鉴国内外的发展经验,不断探索、谋求体制机制的新突破。

关键词：转化医学国家重大科技基础设施国内外比较启示