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再热除湿单元式空调机的设计改进及实验研究

制冷学报 2024年第3期45卷 112-119页

作者：解云鹏时竞竞特灵空调系统(中国)有限公司上海200051 苏州大学电子信息学院苏州215031 上海理工大学能源与动力工程学院上海200093

为了满足在不同空调负荷下能够除湿的同时输送舒适的空气温度和相对湿度,设计并搭建了一种新型的可调节再热除湿系统,优化制冷模式和除湿再热两种模式的制冷剂管理以及改进再热运行开度区间,并对比分析了不同再热盘管方案。实验结果表明... 详细信息

为了满足在不同空调负荷下能够除湿的同时输送舒适的空气温度和相对湿度,设计并搭建了一种新型的可调节再热除湿系统,优化制冷模式和除湿再热两种模式的制冷剂管理以及改进再热运行开度区间,并对比分析了不同再热盘管方案。实验结果表明:新式微通道再热盘管应用于风冷单元式空调机组能够更好地平衡制冷与除湿再热模式对充注量的需求;在除湿再热模式额定工况下的能效EER提高了17%;除湿能力增加了6%;制冷剂通过三通阀流向再热盘管的可调节开度范围从20%~70%提升至15%~85%,增大了空气侧再热温升的调节范围,额定除湿再热工况再热温升从8.3~14.4℃的调节区间增至6.1~19.4℃。既能提升再热可调节运行范围,增大除湿能力又更加节能。

关键词：再热除湿制冷剂管理单元式空调机可调节再热微通道再热盘管

高地应力-化学侵蚀耦合作用下炭质板岩蠕变试验及非线性蠕变损伤模型

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中南大学学报（自然科学版） 2024年第2期55卷 789-798页

作者：陈秋南贺泳超陈湘生谢云鹏黄小城湖南科技大学岩土工程稳定控制与健康监测湖南省重点实验室湖南湘潭411201 湖南科技大学资源环境与安全工程学院湖南湘潭411201 深圳大学土木与交通工程学院广东深圳518060 山东大学岩土与工程结构研究中心山东济南250061

为克服高程障碍并降低施工风险,可采用长大隧道穿越崇山峻岭,但这些隧道往往处于深埋高地应力环境,并受到化学侵蚀影响。为了解决此问题,以丽江—香格里拉炭质板岩大变形隧道为研究对象,采用室内试验和理论推导,研究深埋炭质板岩隧道受... 详细信息

为克服高程障碍并降低施工风险,可采用长大隧道穿越崇山峻岭,但这些隧道往往处于深埋高地应力环境,并受到化学侵蚀影响。为了解决此问题,以丽江—香格里拉炭质板岩大变形隧道为研究对象,采用室内试验和理论推导,研究深埋炭质板岩隧道受化学侵蚀作用下的围岩变形特性。在Poyting-Thomson体蠕变体的基础上,根据模型元件的力学特性,叠加了损伤元件、化学损伤元件和非线性元件,提出高地应力-化学侵蚀耦合作用下炭质板岩非线性蠕变损伤本构关系。研究结果表明:1)炭质板岩试样受化学侵蚀影响显著,侵蚀90 d试样所产生的轴向蠕变应变为侵蚀0 d试样的2.02倍,侵蚀60 d试样所产生的径向蠕变为侵蚀0 d试样的1.85倍;2)受侵蚀的炭质板岩试样在三轴压缩状态下破裂以斜向贯通裂隙为主,并产生一定的滑移错动裂隙,且沿轴线的拉伸劈裂破坏受围压作用抑制明显,未产生竖向贯通裂隙。

关键词：炭质板岩隧道高地应力化学侵蚀耦合作用蠕变试验非线性蠕变损伤本构模型

安罗替尼通过调控NF-κB信号通路对脑胶质瘤细胞恶性表型的影响

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中国药房 2024年第2期35卷 192-197页

作者：柳新李青山谢云鹏张圣林董怡承德医学院附属医院肿瘤科河北承德067000 承德医学院附属医院神经外科河北承德067000

目的探究安罗替尼通过调控核因子κB(NF-κB)信号通路对脑胶质瘤细胞恶性表型的影响。方法体外培养人脑胶质瘤T98G细胞,以5-氟尿嘧啶为阳性对照药物,考察不同浓度(5、10、20μmol/L)安罗替尼对该细胞增殖、黏附、迁移、侵袭能力和上皮... 详细信息

目的探究安罗替尼通过调控核因子κB(NF-κB)信号通路对脑胶质瘤细胞恶性表型的影响。方法体外培养人脑胶质瘤T98G细胞,以5-氟尿嘧啶为阳性对照药物,考察不同浓度(5、10、20μmol/L)安罗替尼对该细胞增殖、黏附、迁移、侵袭能力和上皮间质转化(EMT)相关蛋白[上皮钙黏着蛋白(E-cadherin)、神经钙黏着蛋白(N-cadherin)、波形蛋白(vimentin)、纤维连接蛋白(FN)]表达的影响,并通过加入NF-κB信号通路抑制剂(BAY 11-7082)和激活剂(prostratin)来验证安罗替尼上述作用的可能机制。结果5、10、20μmol/L的安罗替尼均可显著降低细胞的增殖活力(5μmol/L安罗替尼组除外)和迁移率,显著减少黏附细胞数和侵袭细胞数,显著上调E-cadherin蛋白的表达并下调N-cadherin、vimentin、FN蛋白的表达(P0.05);与10μmol/L安罗替尼比较,通路抑制剂可使细胞增殖、黏附、迁移、侵袭能力以及N-cadherin、vimentin、FN、磷酸化NF-κB p65蛋白的表达显著降低,E-cadherin蛋白的表达显著上调(P<0.05),而通路激活剂则可使上述指标显著逆转(P<0.05)。结论安罗替尼可抑制人脑胶质瘤T98G细胞的增殖、黏附、迁移和侵袭,上述作用可能与通过抑制NF-κB信号通路进而抑制细胞EMT样进程有关。

关键词：脑胶质瘤安罗替尼核因子κB信号通路上皮间质转化

An integrated review of automation and robotic technologies for structural prefabrication and construction

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Transportation Safety and Environment 2020年第2期2卷 81-96页

作者： Cheav Por Chea Yu Bai Xuebei Pan Mehrdad Arashpour yunpeng xie Department of Civil Engineering Monash UniversityClaytonVIC 3800Australia Department of Civil Engineering Hefei University of TechnologyHefei230009China Department of Civil Engineering Hunan University of Science and TechnologyXiangtanHunan411201China

Building construction has developed from the use of primitive tools to that of machinery,with a tendency toward *** of processes and robotics can improve efficiency,accuracy and safety in *** the other hand,structural prefabrication for construction is increasingly being adopted worldwide to enhance productivity and to alleviate the environmental impact of conventional construction *** combination and application of automation and prefabrication technologies may therefore introduce new developments to the construction *** paper provides a comprehensive review of the use of automation technology for structural prefabrication and construction,including recent developments,challenges and future *** stages following the sequence of construction are proposed:design,construction management,robotic manufacturing,autonomous transportation and automatic structural *** paper concludes that the widespread use of automation technology is preferable to structural prefabrication for construction,and that the design for robotic construction introduced through connection innovations may be beneficial as a means of avoiding complex operations and thus improving the efficiency of robotic assembly processes.

关键词： prefabrication autonomous transport system robotic construction construction automation building information modelling(BIM)

安罗替尼对脑胶质瘤T98G细胞迁移侵袭及上皮间质转化的抑制作用

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临床神经外科杂志 2024年第3期21卷 286-291页

作者：柳新张圣林李青山董怡谢云鹏承德医学院附属医院肿瘤科承德067000 承德医学院附属医院神经外科承德067000

目的探究安罗替尼对人脑胶质瘤细胞黏附、迁移、侵袭和上皮间质转化(EMT)的影响。方法体外培养人脑胶质瘤T98G细胞,分为对照组(不做干预)、实验组(2.5μmol·L^(-1)安罗替尼组、5μmol·L^(-1)安罗替尼组、10μmol·L^(-1)安罗替尼组)... 详细信息

目的探究安罗替尼对人脑胶质瘤细胞黏附、迁移、侵袭和上皮间质转化(EMT)的影响。方法体外培养人脑胶质瘤T98G细胞,分为对照组(不做干预)、实验组(2.5μmol·L^(-1)安罗替尼组、5μmol·L^(-1)安罗替尼组、10μmol·L^(-1)安罗替尼组)和阳性药物组(50 mg·L^(-1)5-氟尿嘧啶),干预24 h。用活细胞计数(CCK-8)、细胞黏附实验、划痕法、Transwell小室及蛋白免疫印迹(WB)法对细胞增殖活力、黏附、迁移、侵袭能力及EMT相关蛋白表达量进行分析。结果与对照组比较,5μmol·L^(-1)、10μmol·L^(-1)安罗替尼组和阳性药物组增殖活力显著降低(P0.05)。结论安罗替尼可能是通过抑制EMT进程进而抑制人脑胶质瘤T98G细胞的增殖、黏附、迁移、侵袭能力。

关键词：安罗替尼脑胶质瘤黏附迁移侵袭上皮间质转化

安罗替尼通过NF-κB信号通路对脑胶质瘤细胞增殖、凋亡的影响

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山东医药 2024年第7期64卷 48-51页

作者：柳新谢云鹏张圣林李青山董怡承德医学院附属医院肿瘤科河北承德067000 承德医学院附属医院神经外科

目的探讨安罗替尼通过核因子κB(NF-κB)信号通路对人脑胶质瘤细胞(T98G细胞)增殖、凋亡的影响。方法体外培养T98G细胞,并将其随机分为对照组、5μmol/L安罗替尼组、10μmol/L安罗替尼组、20μmol/L安罗替尼组、阳性药物组、抑制剂组。... 详细信息

目的探讨安罗替尼通过核因子κB(NF-κB)信号通路对人脑胶质瘤细胞(T98G细胞)增殖、凋亡的影响。方法体外培养T98G细胞,并将其随机分为对照组、5μmol/L安罗替尼组、10μmol/L安罗替尼组、20μmol/L安罗替尼组、阳性药物组、抑制剂组。对照组不予干预,5μmol/L安罗替尼组、10μmol/L安罗替尼组、20μmol/L安罗替尼组分别以5、10、20μmol/L安罗替尼进行干预,阳性药物组以50 mg/L的5-氟尿嘧啶进行干预,抑制剂组加入10μmol/L安罗替尼+5μmol/L NF-κB通路抑制剂BAY 11-7082进行干预。用CCK-8法检测细胞活力,用5-乙炔基-2'脱氧尿嘧啶核苷法测算细胞增殖率,用Hoechst33258染色法测算细胞凋亡率,用Western blotting法检测细胞增殖、凋亡相关蛋白与NF-κB信号通路相关蛋白[细胞周期蛋白D1(Cyclin D1)、半胱氨酸天冬氨酸蛋白水解酶3(Caspase-3)、NF-κB p65、磷酸化NF-κB p65(NF-κB p65)]表达。结果与对照组比较,5μmol/L安罗替尼组细胞活力差异无统计学意义(P>0.05),10、20μmol/L安罗替尼组、阳性药物组的细胞活力低(P均0.05);与10μmol/L安罗替尼组比较,抑制剂组各指标变化更明显(P均<0.05)。结论安罗替尼可能通过抑制NF-κB通路信号抑制人脑胶质瘤细胞增殖,并促进其凋亡。

关键词：脑胶质瘤安罗替尼核因子κB信号通路细胞增殖细胞凋亡

The Origin of Mesozoic A-type Granitoids,Fujian Province,Southeast China:Insights from Geochronology,Mineralogy and Geochemistry

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Acta Geologica Sinica(English Edition) 2024年第3期98卷 630-640页

作者： xie Qifeng DONG yunpeng CAI Yuanfeng ZHAI Mingguo XIAO Aifang ZHANG Hong Zijin School of Geology and Mining Fuzhou UniversityFuzhou 350108China State Key Laboratory of Continental Dynamics Northwest UniversityXi’an 710069China State Key Laboratory for Mineral Deposits Research Nanjing UniversityNanjing 210023China State Key Laboratory of Lithospheric Evolution Institute of Geology and GeophysicsChinese Academy of SciencesBeijing 100029China

The magma sources,origins and precise forming ages of the miarolite from Qishan and Kuiqi intrusions are still *** results reveal that,miarolites from the Qishan and Kuiqi intrusions yield crystallization ages of~101 and~98 Ma,and they have a high formation temperature(~910℃)and low oxygen fugacity value,indicating crystallization condition at low pressure in the upper crust with temperature of 678℃.The Qishan and Kuiqi miarolites are characterized by enrichment in SiO_(2) and high-K alkali,depletion in Ca and Mg,and belong to the high-K weak peraluminous rock *** samples are enriched in HFSEs(i.e.,Ta,Zr and Hf)and LILEs(i.e.,Ba,P and Sr),depleted in Ba and Sr with the negative anomaly of *** the primitive mantle normalized trace element spider diagram,the samples show a right-inclined‘seagull-type’pattern,combined the ratios of(La/Yb)_(N),10000×Al/Ga,Rb/Nb and Nb/Ta etc.,they were proved to be alkaline A-type *** the characterize of the trace elements,they were derived from clay-rich source accompanied pelite melting,and subjected to K-feldspar crystallization *** values of ε_(Hf)(t)and tDM2 are distributed in the range of-2.8 to 3.3 with~1.2 Ga,and-6.0 to 4.0 with~1.2 Ga,revealing that they were generated from the Mesoproterozoic Cathaysia basement *** comprehensive research reveals the Kuiqi and Qishan intrusions derived from crust-mantle mixing and partial melting of the crust,respectively,resulting from lithospheric extension generated by the Paleo-Pacific Plate subducted into the European-Asian Plate.

关键词： A-type granitoid geochronology extension subduction Mesozoic Southeast China

Crystallographic Characterization of Lu_(2)O@C_(s)(6)-C_(82)and Er_(2)O@C_(s)(6)-C_(82):The Role of Metal Species on Cluster Configuration

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Chinese Journal of Chemistry 2023年第16期41卷 1915-1920页

作者： Pengwei Yu Haocheng Mei Shuaifeng Hu Changwang Pan Wangqiang Shen Pengyuan Yu Kun Guo yunpeng xie Takeshi Akasaka Lipiao Bao Xing Lu Stote Key Laboratory of Materials Processing and Die&Mould Technology School of Materials Science and EngineeringHuazhongUniversity of Science and Technology1037 Luoyu RoadWuhanHubei 430074China Jiangxi Province Key Laboratory of Coordination Chemistry School of Chemistry and Chemical EngineeringJinggangshan University28 Xueyuan RoadJianJiangxi 343009China.

Comprehensive Summary Intramolecular interactions are fundamental for the unique structures and outstanding properties of ***,how the internal metal species interplay with the cluster configuration inside oxide clusterfullerenes remains poorly ***,we successfully captured two oxide clusterfullerenes with different metals,namely,Lu_(2)O@C_(82)and Er_(2)O@C_(82),to elucidate the role of metal species in tuning cluster *** two molecules have been fully characterized by mass spectrometry,Vis-NIR absorption spectroscopy,cyclic voltammetry,and single-crystal X-ray diffraction.

关键词： Fullerenes Crystal growth Structure elucidation Host-guest systems π-πstacking Fullerenes Crystal growth Structure elucidation Host-guest systems π--πstacking

A Deep Learning-Enabled Skin-Inspired Pressure Sensor for Complicated Recognition Tasks with Ultralong Life

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Research 2024年第1期2023卷 443-454页

作者： Yingxi xie Xiaohua Wu Xiangbao Huang Qinghua Liang Shiping Deng Zeji Wu yunpeng Yao Longsheng Lu School of Mechanical&Automotive Engineering South China University of TechnologyGuangzhouChina

Flexible full-textile pressure sensor is able to integrate with clothing directly,which has drawn extensive attention from scholars *** the realization of flexible full-textile pressure sensor with high sensitivity,wide detection range,and long working life remains *** recognition tasks necessitate intricate sensor arrays that require extensive data processing and are susceptible to *** human skin is capable of interpreting tactile signals,such as sliding,by encoding pressure changes and performing complex perceptual *** by the skin,we have developed a simple dip-and-dry approach to fabricate a full-textile pressure sensor with signal transmission layers,protective layers,and sensing *** sensor achieves high sensitivity(2.16 kPa^(−1)),ultrawide detection range(0 to 155.485 kPa),impressive mechanical stability of 1 million loading/unloading cycles without fatigue,and low material *** signal transmission layers that collect local signals enable real-world complicated task recognition through one single *** developed an artificial Internet of Things system utilizing a single sensor,which successfully achieved high accuracy in 4 tasks,including handwriting digit recognition and human activity *** results demonstrate that skin-inspired full-textile sensor paves a promising route toward the development of electronic textiles with important potential in real-world applications,including human–machine interaction and human activity detection.

关键词： Deep Skin utilizing