检索结果-南通市图书馆

Regenerative Biomaterials 2022年第1期9卷 750-760页

作者： Hao wu Yuan Gao Jia Ma Maosong Hu Jing Xia Shuting Bao yuxi Liu Kai Feng College of Materials&Chemical Engineering Chuzhou UniversityChuzhou 239000China Department of Oncology Beijing Shunyi HospitalShunyi DistrictBeijing 101300China Department of Neurology Beijing Shunyi HospitalShunyi DistrictBeijing 101300China

Acute myelogenous leukemia(AML)remains a serious fatal disease for the patients and effective treatment strategies are urgently *** on the characteristics of the AML,we developed the CD44 and bone targeting liposomes delivery system decorated with the redox-cleavable ***,ALN-HA was obtained by amination between alendronate(ALN)and hyaluronic acid(HA),and cholesterol(Chol)was coupled by a disulfide linker(-SS-)with biological reducibility to obtain the goal polymer,ALN-HA-SS-Chol,decorated the liposomes loaded with the Cytarabine(AraC).ALN-HA-SS-AraC-Lip exhibited a spherical morphology with the diameter of 117.5nm and expanded at the environment of 10mM ***,compared with other groups,ALN-HA-SS-AraC-Lip showed benign hydroxyapatite affinity in vitro and bone targeting in C57/BL6 mice,also,ALN-HA-SS-AraC-Lip exhibited encouraging antitumor which significantly reduced the white blood cell amount in bone marrow and blood smear caused by AML model,besides,the dual targeting liposomes also prolong the survival time of *** conclusion,the bone and CD44 dual targeting liposomes with redox sensitivity could target to the leukemia stem cells regions and then uptake by the tumor cells,which would be a valuable target for the treatment of the AML.

关键词： cytarabine liposomes acute myeloid leukemia hyaluronic acid

Ultrafast-laser-treated poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate)electrodes with enhanced conductivity and transparency for semitransparent perovskite solar cells

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers of Chemical Science and Engineering 2023年第2期17卷 206-216页

作者： Yongshun Wang yuxi Dou Zhengzhe wu Yingxin Tian Yiming Xiong Juan Zhao De Fang Fuzhi Huang Yi-Bing Cheng Jie Zhong State Key Laboratory of Advanced Technology of Materials Composite Technology Wuhan University of TechnologyWuhan 430070China Foshan Xianhu Laboratory of the Advanced Energy Science and Technology Guangdong Laboratory Foshan 528216China School of Automobile Engineering Wuhan University of TechnologyWuhan 430070China Center for Materials Research and Analysis Wuhan University of TechnologyWuhan 430070China

Poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate)(PEDOT:PSS)is an important organic electrode for solution-processed low-cost electronic ***,it requires doping and post-solvent treatment to improve its conductivity,and the chemicals used for such treatments may affect the device fabrication *** this study,we developed a novel route for exploiting ultrafast lasers(femtosecond and picosecond laser)to simultaneously enhance the conductivity and transparency of PEDOT:PSS films and fabricate patterned solution-processed electrodes for electronic *** conductivity of the PEDOT:PSS film was improved by three orders of magnitude(from 3.1 to 1024 S·cm^(–1)),and high transparency of up to 88.5%(average visible transmittance,AVT)was *** and depthprofiling X-ray photoelectron spectroscopy revealed that the oxidation level of PEDOT was enhanced,thereby increasing the carrier *** surface PSS content also decreased,which is beneficial to the carrier mobility,resulting in significantly enhanced electrical ***,we fabricated semitransparent perovskite solar cells using the as-made PEDOT:PSS as the transparent top electrodes,and a power conversion efficiency of 7.39%was achieved with 22.63%***,the proposed route for synthesizing conductive and transparent electrodes is promising for vacuum and doping-free electronics.

关键词： PEDOT:PSS ultrafast laser transparent electrode ST-PSCs patterning

Random Raman Fiber Laser as a Liquid Refractive Index Sensor

在线全文

学校读者我要写书评

暂无评论

Photonic Sensors 2024年第1期14卷 13-22页

作者： Bing HAN yuxi MA Han wu Yong ZHAO College of Information Science and Engineering Northeastern UniversityShenyang 110819China Hebei Key Laboratory of Micro-Nano Precision Optical Sensing and Measurement Technology Qinhuangdao 066004China College of Electronics and Information Engineering Sichuan UniversityChengdu 610064China

In this paper,a new concept of forward-pumped random Raman fiber laser(RRFL)-based liquid refractive index sensing is proposed for the first *** liquid refractive index sensing,the flat fiber end immersed in the liquid can act as the point reflector for generating random fiber lasing and also as the sensing *** to the high sensitivity of the output power of the RRFL to the reflectivity provided by the point reflector in the ultralow reflectivity regime,the proposed RRFL is capable of achieving liquid refractive index sensing by measuring the random lasing output *** theoretically investigate the effects of the operating pump power and fiber length on the refractive index sensitivity for the proposed *** a proof-of-concept demonstration,we experimentally realize high-sensitivity half-open short-cavity RRFL-based liquid refractive index sensing with the maximum sensitivity and the sensing resolution of-39.88W/RIU and 2.5075×10^(-5) RIU,*** also experimentally verify that the refractive index sensitivity can be enhanced with the shorter fiber length of the *** work extends the application of the random fiber laser as a new platform for highly-sensitive refractive index sensing in chemical,biomedical,and environmental monitoring applications,etc.

关键词： Fiber optic sensors refractive index measurements fiber lasers Rayleigh scattering stimulated Raman scattering

不同Wagner分级糖尿病足患者血清外泌体miR-3976的表达及机制

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中华临床医师杂志（电子版） 2019年第6期13卷 401-408页

作者：刘静陈红星刘兴州吴雨茜蓝碧云麦梨芳杨川严励任萌中山大学孙逸仙纪念医院内分泌科

目的观察不同Wagner分级的糖尿病患者血清及血清外泌体内microRNA-3976(miR-3976)的表达变化,并探讨其表达异常的可能机制。方法选取2018年3~6月中山大学孙逸仙纪念医院内分泌科28例糖尿病患者,通过逆转录-实时荧光定量聚合酶链式反应(R... 详细信息

目的观察不同Wagner分级的糖尿病患者血清及血清外泌体内microRNA-3976(miR-3976)的表达变化,并探讨其表达异常的可能机制。方法选取2018年3~6月中山大学孙逸仙纪念医院内分泌科28例糖尿病患者,通过逆转录-实时荧光定量聚合酶链式反应(RT-qPCR)法检测血清及血清外泌体内miR-3976的表达水平,采用t检验比较不同Wagner分级糖尿病患者血清及血清外泌体miR-3976的表达差异。体外培养皮肤成纤维细胞和角质形成细胞,分别给予高糖、甘露醇及正常糖浓度培养,RT-qPCR法检测miR-3976的表达水平,采用单因素方差分析比较3种处理情况下细胞内miR-3976的表达差异。对miR-3976进行生物信息学分析。结果Wagner 3~4级糖尿病足患者与Wagner 0~2级患者相比,血清miR-3976表达水平显著升高(1.588±1.118 vs 1.068±0.108),差异具有统计学意义(t=3.256,P=0.0031),且血清外泌体中的miR-3976升高更显著(2.885±0.742 vs 1.156±0.220),差异具有统计学意义(t=2.435,P=0.0255);高糖培养的成纤维细胞中miR-3976表达较正常糖及等渗甘露醇组显著升高(3.749±1.177 vs 1.000;3.749±1.177 vs 2.060±0.475),差异均具有统计学意义(q=6.497、3.992,P均<0.05),而HaCaT细胞在高糖、等渗甘露醇及正常糖培养情况下miR-3976表达差异无统计学意义(F=0.249,P=0.789)。miR-3976的靶基因KEGG信号通路分析结果显示靶基因在细胞间紧密连接信号通路上富集程度最高。结论Wagner 3~4级的糖尿病足患者血清中升高的miR-3976可能主要以外泌体的形式存在,且可能主要来源于伤口局部的成纤维细胞,并通过外泌体将表达增高的miR-3976传递至皮肤修复细胞,影响细胞紧密连接分子表达,从而抑制伤口愈合。

关键词：糖尿病足 Wagner 分级外泌体 miRNA 生物信息学

在线全文

学校读者我要写书评

暂无评论

沙棘优良杂交种质资源鉴定及筛选

黑龙江农业科学 2024年第3期 51-57页

作者：王蕊唐克吴雨蹊张莉莉马骁房磊李鹏举王明洁黑龙江省农业科学院乡村振兴科技研究所黑龙江哈尔滨150028 黑龙江省农业科学院园艺分院黑龙江哈尔滨150069

为筛选沙棘优良杂交种质资源,本试验以杂交F_1代及其父母本与对照品种中雌沙棘共13份材料为试材,通过调查比较物候期、生长性状、生长速率及果实性状等相关指标,通过建立隶属函数方程,对10份杂交F_1代材料进行综合评价。结果表明,杂交F_... 详细信息

为筛选沙棘优良杂交种质资源,本试验以杂交F_1代及其父母本与对照品种中雌沙棘共13份材料为试材,通过调查比较物候期、生长性状、生长速率及果实性状等相关指标,通过建立隶属函数方程,对10份杂交F_1代材料进行综合评价。结果表明,杂交F_1代果实成熟期为8月13日—15日,介于中国沙棘与蒙古沙棘之间。参试材料平均株高为284.68 cm,平均冠幅为205.85 cm,平均地径为5.47 cm,中蒙杂交沙棘生长性状指标显著高于对照品种中国沙棘雌株与楚伊沙棘,具有树势强,生长速率快的特点。果实百果重平均值为30.33 g,俄罗斯大果沙棘品种楚伊百果重显著高于其他参试材料,中国沙棘雌株百果重最低,为11.21 g。单株产量平均值为8.28 kg,高于母本楚伊沙棘与对照品种中国沙棘雌株,其中中蒙杂雌6材料单株产量最高,为12.25 kg,中国沙棘雌株材料单株产量最低,为2.43 kg。通过综合评价,中蒙杂雌6与中蒙杂雌10综合评价E值高于其他材料,可以作为中熟杂交沙棘种质资源进行保存与推广种植。

关键词：沙棘杂交种质资源

维普期刊数据库博看期刊

Pd/silicalite-1: An highly active catalyst for the oxidative removal of toluene

在线全文

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2022年第6期34卷 209-219页

作者： Linke wu Jiguang Deng yuxi Liu Lin Jing Xiaohui Yu Xing Zhang Ruyi Gao Wenbo Pei Xiuqing Hao Ali Rastegarpanah Hongxing Dai Beijing Key Laboratory for Green Catalysis and Separation Key Laboratory of Beijing on Regional Air Pollution ControlKey Laboratory of Advanced Functional MaterialsEducation Ministry of ChinaLaboratory of Catalysis Chemistry and NanoscienceDepartment of Environmental Chemical EngineeringSchool of Environmental and Chemical EngineeringFaculty of Environment and LifeBeijing University of TechnologyBeijing 100124China

Catalytic combustion is thought as an efficient and economic pathway to remove volatile organic compounds, and its critical issue is the development of high-performance catalytic materials. In this work, we used the in situ synthesis method to prepare the silicalite-1(S-1)-supported Pd nanoparticles(NPs). It is found that the as-prepared catalysts displayed a hexagonal prism morphology and a surface area of 390-440 m^(2)/g. The sample(0.28Pd/S-1-H)derived after reduction at 500°C in 10 vol% H_(2)showed the best catalytic activity for toluene combustion(T50%= 180℃ and T90%= 189℃ at a space velocity of 40,000 m L/(g·hr), turnover frequency(TOFPd) at 160℃ = 3.46 × 10^(-3)sec^(-1), and specific reaction rate at 160℃ = 63.8μmol/(gPd·sec)), with the apparent activation energy(41 k J/mol) obtained over the bestperforming 0.28Pd/S-1-H sample being much lower than those(51-70 k J/mol) obtained over the other samples(0.28Pd/S-1-A derived from calcination at 500℃ in air, 0.26Pd/S-1-im derived from the impregnation route, and 0.27Pd/ZSM-5-H prepared after reduction at 500℃ in 10 vol% H_(2)). Furthermore, the 0.28Pd/S-1-H sample possessed good thermal stability and its partial deactivation due to CO_(2) or H_(2)O introduction was reversible, but SO_(2) addition resulted in an irreversible deactivation. The possible pathways of toluene oxidation over 0.28Pd/S-1-H was toluene → p-methylbenzoquinone → maleic anhydride, benzoic acid, benzaldehyde → carbon dioxide and water. We conclude that the good dispersion of Pd NPs, high adsorption oxygen species concentration, large toluene adsorption capacity, strong acidity,and more Pd~0 species were responsible for the good catalytic performance of 0.28Pd/S-1-H.

关键词： Silicalite-1 Hexagonal prism shape Supported palladium catalyst Volatile organic compound Toluene combustion

Whether and When Superhydrophobic/Superoleophobic Surfaces Are Fingerprint Repellent

在线全文

学校读者我要写书评

暂无评论

Research 2023年第1期2022卷 197-207页

作者： Chengjiao wu Yue Fan Hongxin Wang Juan Li yuxi Chen Yingke Wang Lin Liu Lidan Zhou Shilin Huang Xuelin Tian Key Laboratory for Polymeric Composite Functional Materials of Ministry of Education Guangzhou Key Laboratory of Flexible Electronic Materials and Wearable DevicesSchool of Materials Science and EngineeringSun Yat-sen UniversityGuangzhou 510006China State Key Laboratory of Optoelectronic Materials and Technologies Sun Yat-sen UniversityGuangzhou 510006China School of Traditional Chinese Medicine Resources Guangdong Pharmaceutical UniversityGuangzhou 510006China

Driven by the ever-increasing demand for fingerprint-resistant techniques in modern society,numerous researches have proposed to develop innovative antifingerprint coatings based on superhydrophobic/superoleophobic surface ***,whether superhydrophobic/superoleophobic surfaces have favorable repellency to the microscopic fingerprint is in fact an open ***,we establish a reliable method that enables evaluating the antifingerprint capability of various surfaces in a quantitative *** show that superhydrophobicity is irrelevant with fingerprint *** superoleophobic surfaces,two distinct wetting states of microscopic fingerprint residues,i.e.,the"repellent"and the“collapsed”states,are *** in the"repellent"state,in which the fingerprint residues remain atop surface textures upon being pressed,superoleophobic surfaces can bring about favorable antifingerprint repellency,which correlates positively with their receding contact angles.A finger-deformation-dependent intrusion mechanism is proposed to account for the formation of diferent fingerprint wetting *** findings offer important insights into the mechanism of fingerprint repellency and will help the design of high-performance antifingerprint surfaces for diverse applications.

关键词： deformation mechanism fingerprint

硅烷/石墨烯纳米带/蜜胺泡沫的制备与吸附性能

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

杭州师范大学学报（自然科学版） 2020年第2期19卷 120-126页

作者：古亚丽吴煜熙雷舒静王跃林冯钦邦吴利民沈世长徐江南汤龙程赵丽杭州师范大学有机硅化学及材料技术教育部重点实验室浙江杭州311121 杭州师范大学材料与化学化工学院浙江杭州311121 宜昌科林硅材料有限公司湖北宜昌443007 宜昌汇富硅材料有限公司湖北宜昌443007

以纳米碳纤维(CNF)为原料,经氧化纵向剖开获得750 nm宽带状的氧化石墨烯带(GONR),通过浸涂法将其包裹于蜜胺泡沫(MF)表面,将还原GONR/MF再进行十八烷基三甲氧基硅烷(S)处理,成功制得超疏水亲油、力学回弹性好的硅烷/石墨烯纳米带/蜜胺泡... 详细信息

以纳米碳纤维(CNF)为原料,经氧化纵向剖开获得750 nm宽带状的氧化石墨烯带(GONR),通过浸涂法将其包裹于蜜胺泡沫(MF)表面,将还原GONR/MF再进行十八烷基三甲氧基硅烷(S)处理,成功制得超疏水亲油、力学回弹性好的硅烷/石墨烯纳米带/蜜胺泡沫(S/rGONR/MF).并对材料的微观形貌、力学性能、疏水性、吸附性能、重复使用性与油水分离功能进行了研究.结果表明:石墨烯纳米带与蜜胺泡沫骨架紧密相连,泡沫骨架表面呈现大量褶皱状粗糙结构,且泡沫孔洞结构得到很好保持.疏水角由原来的0°提高到158°.饱和吸油能力达45~70 g/g,且重复使用后吸出的油量仍保持90%以上,可实现对水面浮油与水下重油的高效分离.由此可见,其在油类与有机物泄露污染处理方面有着巨大的应用前景.

关键词：石墨烯纳米带/三聚氰胺泡沫硅烷疏水油水分离

功能近红外光谱技术应用于脑老化前额叶功能特征分析的研究进展

在线全文

学校读者我要写书评

暂无评论

中医康复 2024年第10期1卷 32-37页

作者：汤增铨王佳瑜吴羽皙魏鑫黄嘉莉欧海宁梁俊杰广州医科大学附属第五医院/广东高校生物靶向诊治与康复重点实验室广东广州510700 广州医科大学广东广州511436 佛山市中医院广东佛山528000 广州医科大学康复实验室广东广州510700

脑老化是与年龄增长相关的正常的中枢神经系统退行性改变,与认知、步行和平衡功能的退化密切相关。前额叶(PFC)是参与功能代偿的主要脑区之一,对脑老化带来的功能退化有主要调控作用。利用近年来新兴的功能性近红外光谱技术(fNIRS),同... 详细信息

脑老化是与年龄增长相关的正常的中枢神经系统退行性改变,与认知、步行和平衡功能的退化密切相关。前额叶(PFC)是参与功能代偿的主要脑区之一,对脑老化带来的功能退化有主要调控作用。利用近年来新兴的功能性近红外光谱技术(fNIRS),同步认知、步行和平衡任务可进行动态监测前额叶和其他脑区的皮质血流氧合血红蛋白和脱氧血红蛋白的浓度,并进一步结合血管耦合机制进行脑功能分析,可深入探讨前额叶在脑老化中的调控机制,旨在为今后相关临床实践和研究提供参考。

关键词：脑老化功能性近红外光谱技术(fNIRS) 前额叶认知运动综述

Solution properties and self-association of multi-blocks like copolymer P(AM/AA) prepared by template copolymerization

在线全文

学校读者我要写书评

暂无评论

Frontiers of Chemical Science and Engineering 2007年第1期1卷 68-71页

作者： ZHANG yuxi wu Feipeng LI Miaozhen WANG Erjian Institute of Physics and Chemistry Chinese Academy of SciencesBeijing 100080China

The association and properties of multi-block like copolymers(TP)of acrylamide(AM)and acrylic acid(AA)prepared by template copolymerization in aqueous solution were *** results showed that the copolymers of this type exhibited a significant structure effect compared with that of similar random copolymers(CP)obtained by copoly-merization in the absence of *** the value of pH or adding Ca2+ion to the copolymer solution will make phase separation *** TEM images demonstrated that the phase separation caused by Ca2+ion was due to the forma-tion of extensively intermolecular *** the increase of the pH value of copolymer solution,the changes of the solution viscosity was similar with that of homopoly-acrylic acid,which originally increased and then *** the increase range of template copolymer was higher than that of homopolyacrylic *** images indicated that at the maximal viscosity the copolymer obtained in the presence of template formed coiled aggregates.

关键词： Template copolymer P(AM/AA) structure effect association phase-separation