检索结果-南通市图书馆

Journal of Energy Chemistry 2024年第8期95卷 428-439页

作者： Yuying Fan Ying Gu dongxu Wang Yanqing Jiao Aiping wu Chungui Tian Key Laboratory of Functional Inorganic Material Chemistry Ministry of Education of the People's Republic of China Heilongjiang University College of Chemistry Chemical Engineering and Resource Utilization Northeast Forestry University

Hydrogen evolution reaction（HER） and urea oxidation reaction（UOR） are key reactions of the watercycling associated catalytic process/device.The design of catalysts with a super-hydrophilic/aerophobic structure and optimized electron distribution holds great promise.Here,we have designed a threedimensional（3D） hollow Ni/NiMoN hierarchical structure with arrayed-sheet surface based on a onepot hydrothermal route for efficient urea-assisted HER based on a simple hydrothermal process.The Ni/NiMoN catalyst exhibits super-hydrophilic/aerophobic properties with a small droplet contact angle of 6.07° and an underwater bubble contact angle of 155.7°,thus facilitating an escape of bubbles from the electrodes.Density functional theory calculations and X-ray photoelectron spectroscopy results indicate the optimized electronic structure at the interface of Ni and NiMoN,which can promote the adsorption/desorption of reactants and intermediates.The virtues combining with a large specific surface area endow Ni/NiMoN with efficient catalytic activity of low potentials of 25 mV for HER and 1.33 V for UOR at10 mA cm-2.The coupled HER and UOR system demonstrates a low cell voltage of 1.42 V at 10 mA cm-2,which is approximately 209 mV lower than water electrolysis.

关键词： Hollow heterojunctions Hydrogen evolution Super hydrophilic/aerophobic Transition metal nitrides Urea electrooxidation

Screening of transition metal oxides for electrocatalytic nitrate reduction to ammonia at large currents

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2024年第5期17卷 3902-3910页

作者： Qiongfei wu Weijie Zhu dongxu Ma Chao Liang Zhoucheng Wang Hanfeng Liang State Key Laboratory of Physical Chemistry of Solid Surfaces Tan Kah Kee Innovation LaboratoryCollege of Chemistry and Chemical EngineeringXiamen UniversityXiamen 361005China College of Chemical Engineering Tianjin UniversityTianjin 300072China

Electrochemical nitrate reduction reaction(NO_(3)RR)towards ammonia,as an emerging and appealing technology alternative to the energy-intensive Haber-Bosch process and inefficient nitrogen reduction reaction,has recently aroused wide concern and research.However,the current research of the NO_(3)RR towards ammonia lacks the overall performance comparison of various electrocatalysts.Given this,we here make a comparison of 12 common transition metal oxide catalysts for the NO_(3)RR under a high cathodic current density of 0.25 A·cm^(-2),wherein Co_(3)O_(4) catalyst displays the highest ammonia Faradaic efficiency(85.15%)and moderate activity(ca.-0.25 V vs.reversible hydrogen electrode).Other external factors,such as nitrate concentrations in the electrolyte and applied potential ranges,have also been specifically investigated for the NO_(3)RR.

关键词： nitrate reduction reaction ammonia production transition metal oxides Co_(3)O_(4)

Dual-responsive supramolecular photodynamic nanomedicine with activatable immunomodulation for enhanced antitumor therapy

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Acta Pharmaceutica Sinica B 2024年第2期14卷 765-780页

作者： Siqin He Lulu Wang dongxu wu Fan Tong Huan Zhao Hanmei Li Tao Gong Huile Gao Yang Zhou Key Laboratory of Tropical Biological Resources of Ministry of Education School of Pharmaceutical SciencesHainan UniversityHaikou 570200China Key Laboratory of Drug-Targeting and Drug Delivery System West China School of PharmacySichuan UniversityChengdu 610041China Revvity Inc. WalthamMA 02451USA School of Food and Biological Engineering Chengdu UniversityChengdu 610106China

A major challenge facing photodynamic therapy(PDT) is that the activity of the immuneinduced infiltrating CD8^(+)T cells is subject to the regulatory T lymphocytes(Tregs), leaving the tumor at risk of recurrence and metastasis after the initial ablation. To augment the antitumor response and reprogram the immunosuppressive tumor microenvironment(TME), a supramolecular photodynamic nanoparticle(DACss) is constructed by the host-guest interaction between demethylcantharidin-conjugated β-cyclodextrin(DMC-CD) and amantadine-terminated disulfide-conjugated FFVLGGGC peptide with chlorin e6 decoration(Ad-ss-pep-Ce6) to achieve intelligent delivery of photosensitizer and immunomodulator for breast cancer treatment. The acid-labile β-carboxamide bond of DMC-CD is hydrolyzed in response to the acidic TME, resulting in the localized release of DMC and subsequent inhibition of Tregs.The guest molecule Ad-ss-pep-Ce6 can be cleaved by a high level of intracellular GSH, reducing photosensitizer toxicity and increasing photosensitizer retention in the tumor. With a significant increase in the CTL/Treg ratio, the combination of Ce6-based PDT and DMC-mediated immunomodulation adequately achieved spatiotemporal regulation and remodeling of the TME, as well as improved primary tumor and in situ lung metastasis suppression with the aid of PD-1 antibody.

关键词： Photodynamic therapy Immunosuppressive microenvironment Immunomodulator Dual-responsive Supramolecularassembly Checkpointblockade

Self-fueling ferroptosis-inducing microreactors based on p H-responsive Lipiodol Pickering emulsions enable transarterial ferro-embolization therapy

在线全文

学校读者我要写书评

暂无评论

National Science Review 2024年第1期11卷 74-85页

作者： Chunjie Wang Lei Zhang Zhijuan Yang dongxu Zhao Zheng Deng Jialu Xu Yumin wu Yu Hao Ziliang Dong Liangzhu Feng Zhuang Liu Institute of Functional Nano & Soft Materials (FUNSOM) Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices Soochow University Center of Interventional Radiology & Vascular Surgery Department of Radiology Zhongda Hospital Medical School Southeast University Department of Interventional Radiology The First Afflliated Hospital of Soochow University

Lipiodol chemotherapeutic emulsions remain one of the main choices for the treatment of unresectable hepatocellular carcinoma(HCC) via transarterial chemoembolization(TACE). However, the limited stability of Lipiodol chemotherapeutic emulsions would lead to rapid drug diffusion, which would reduce the therapeutic benefit and cause systemic toxicity of administrated chemotherapeutics. Therefore, the development of enhanced Lipiodol-based formulations is of great significance to enable effective and safe TACE treatment. Herein, a stable water-in-oil Lipiodol Pickering emulsion(LPE) stabilized by pH-dissociable calcium carbonate nanoparticles and hemin is prepared and utilized for efficient encapsulation of lipoxygenase(LOX). The obtained LOX-loaded CaCO3&hemin-stabilized LPE(LHCa-LPE) showing greatly improved emulsion stability could work as a pH-responsive and self-fueling microreactor to convert polyunsaturated fatty acids(PUFAs), a main component of Lipiodol, to cytotoxic lipid radicals through the cascading catalytic reaction driven by LOX and hemin, thus inducing ferroptosis of cancer cells. As a result, such LHCa-LPE upon transcatheter embolization can effectively suppress the progression of orthotopic N1S1 HCC in rats. This study highlights a concise strategy to prepare pH-responsive and stable LPE-based self-fueling microreactors, which could serve as bifunctional embolic and ferroptosis-inducing agents to enable proof-of-concept transarterial ferro-embolization therapy of HCC.

关键词： CaCO3 nanoparticles Pickering emulsion ferroptosis lipid peroxidation transarterial ferro-embolization

A high-performance electromagnetic energy harvester for scavenging ultra-low frequency vibration energy of human foot movement

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Science China(Technological Sciences) 2024年第5期67卷 1391-1400页

作者： HU JiaJun QIAN Shuo wu Hui HU dongxu NIU LiXin BI XiaoXue ZHANG Jie HOU XiaoJuan GENG WenPing MU JiLiang HE Jian CHOU XiuJian Science and Technology on Electronic Test and Measurement Laboratory North University of ChinaTaiyuan030051China School of Software North University of ChinaTaiyuan030051China

In our daily lives,low-frequency kinetic energy primarily manifests as vibrations.However,effective harnessing of lowfrequency kinetic energy remains a formidable challenge.This paper proposes a rope-driven rotor that rotates around an axis and consists of an ultra-high-molecular-weight polyethylene(UHMWPE)wire wrapped around a metal shaft.The rotor can convert ultra-low frequency vibration/linear motion into rapid rotation by pressing the top at low frequencies and driving the rope for a quick release.The harvester can generate up to 36.25 m W power using a 0.1-mm-diameter UHMWPE wire as the rotor when periodically pressed down to 20 mm at a frequency of 1 Hz.A simple power generation floor is assembled,generating 28.58-m W power with a matching load at a frequency of 1.5 Hz.Moreover,the harvester can increase the charging voltage of a 0.47-F supercapacitor from 0 to 6.8 V within 10 min.In addition,the harvester can harvest energy through a light finger press motion,and the energy obtained can also support the continuous operation of multiple electronic devices concurrently.This study introduces an effective method for harvesting ultra-low frequency energy and has great prospects in the field of power generation floor and human movement energy harvesting.

关键词： electromagnetic energy harvester rope-shaft coupling structure human motion ultra-low frequency

Barocaloric Material with High Thermal Conductivity for Room-Temperature Refrigeration

在线全文

学校读者我要写书评

暂无评论

Journal of Thermal Science 2023年第6期32卷 2115-2125页

作者： ZHU Liutao DAI Zhaofeng GAO Yuanzhi wu dongxu WANG Changling ZHAO Dongliang SHE Xiaohui DING Yulong ZHANG Xiaosong School of Energy&Environment Southeast UniversityNanjing210096China School of Mechanical Engineering Shijiazhuang Tiedao UniversityShijiazhuang050043China Birmingham Centre for Energy Storage School of Chemical EngineeringUniversity of BirminghamBirminghamB152TTUK Engineering Research Center of Building Equipment Energyand EnvironmentMinistry of EducationNanjing210096China

Barocaloric refrigeration technology,one of the caloric-effect refrigeration technologies,is drawing more and more attention.Neopentyl glycol(NPG)was reported to have a giant barocaloric effect,making it a potential barocaloric material.However,the high solid-solid(S-S)phase transition temperature and low thermal conductivity hinder the application of NPG in barocaloric refrigeration.This work lowers the S-S phase transition temperature and improves the thermal conductivity of the NPG-based barocaloric material.An NPG/TMP(TMP:Trimethylolpropane)binary system with an S-S phase transition temperature of 283.15 K is prepared,in which the mass ratio of TMP is 20%.Graphene is then added to the binary system to enhance thermal conductivity,and the optimal mass ratio of graphene was determined to be 5%.The thermal conductivity of this composite is 0.4 W/(m·K),increased by 110%compared to the binary system.To predict the effect of enhanced thermal conductivity on the cold-extraction process of the barocaloric refrigeration cycle,a numerical model is developed.The results show that the cold-extraction time of the barocaloric refrigeration cycle utilizing the composite with 5%graphene as the refrigerant is shortened by 50%compared with that using the binary system.

关键词： barocaloric refrigeration plastic crystal graphene performance enhancement numerical simulation

Toward Establishing a Low-cost UAV Coordinated Carbon Observation Network(LUCCN):First Integrated Campaign in China

在线全文

学校读者我要写书评

暂无评论

Advances in Atmospheric Sciences 2024年第1期41卷 1-7页

作者： dongxu YANG Tonghui ZHAO Lu YAO Dong GUO Meng FAN Xiaoyu REN Mingge LI Kai wu Jing WANG Zhaonan CAI Sisi WANG Jiaxu GUO Liangfu CHEN Yi LIU Carbon Neutrality Research Center(CNRC) Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China Key Laboratory of Middle Atmospheric Physics and Global Environment Observation(LAGEO) Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China State Key Laboratory of Remote Sensing Science Aerospace Information Research InstituteChinese Academy of SciencesBeijing 100101China National Remote Sensing Center of China Beijing 100036China The Administrative Center for China’s Agenda 21 Beijing 100862China

In this study,we introduce our newly developed measurement-fed-perception self-adaption Low-cost UAV Coordinated Carbon Observation Network(LUCCN)prototype.The LUCCN primarily consists of two categories of instruments,including ground-based and UAV-based in-situ measurement.We use the GMP343,a low-cost non-dispersive infrared sensor,in both ground-based and UAV-based instruments.The first integrated measurement campaign took place in Shenzhen,China,4 May 2023.During the campaign,we found that LUCCN’s UAV component presented significant data-collecting advantages over its ground-based counterpart owing to the relatively high altitudes of the point emission sources,which was especially obvious at a gas power plant in Shenzhen.The emission flux was calculated by a crosssectional flux(CSF)method,the results of which differed from the Open-Data Inventory for Anthropogenic Carbon dioxide(ODIAC).The CSF result was slightly larger than others because of the low sampling rate of the whole emission cross section.The LUCCN system will be applied in future carbon monitoring campaigns to increase the spatiotemporal coverage of carbon emission information,especially in scenarios involving the detection of smaller-scale,rapidly varying sources and sinks.

关键词： CO_(2) measurement networks power station carbon emission cross-sectional flux method

Restoration of formation processes of dolomite reservoirs based on laser U-Pb dating: A case study of Ordovician Majiagou Formation, Ordos Basin, NW China

在线全文

学校读者我要写书评

暂无评论

Petroleum Exploration and Development 2022年第2期49卷 327-338页

作者： ZHOU Jingao YU Zhou wu dongxu REN Junfeng ZHANG Daofeng WANG Shaoyi YIN Chen LIU Yuxin PetroChina Hangzhou Research Institute of Geology Hangzhou 310023China CNPC Key Laboratory of Carbonate Reservoir Hangzhou 310023China PetroChina Changqing Oilfield Company Xi'an 710018China China University of Petroleum(Beijing) Beijing 102249China

To address the issue of non-unique interpretation of dolomite reservoir diagenetic and porosity evolution in the previous qualitative or semi-quantitative studies, we investigate two dolomite reservoir types, i.e. weathering-crust karstic reservoirs and mound-beach reservoirs, in the Ordovician Majiagou Formation, Ordos Basin by using in-situ laser ablation U-Pb dating as well as carbon and oxygen isotopic composition analysis. The results show that:(1) According to the dating of 8 reservoir samples, the Majiagou Formation experienced 5 diagenetic stages(Stage 1: deposition of matrix dolomite or penecontemporaneous dolomitization, in 444.0–494.0 Ma;Stage 2: dogtooth-or blade-shaped dolomite cementation, in 440.0–467.0 Ma;Stage 3: dolomitic silt filling, in 316.5–381.0 Ma;Stage 4: crystalline dolomite filling, in 354.0 Ma;Stage 5: crystalline calcite filling, in 292.7–319.0 Ma).(2) Supra-salt weathering-crust karstic dolomite reservoirs went through several diagenetic processes including penecontemporaneous dolomitization, compaction, weathering-crust karstification, packing, and rupturing in succession. Gypsum mold pores formed in the phase of hypergenic karstification and were filled with such minerals as dolomitic silts and calcites, and thus the porosity decreased from 10%–40% to 3%–8%.(3) Sub-salt mound-beach dolomite reservoirs went through the diagenetic processes including penecontemporaneous dolomitization, compaction, subsea cementation, penecontemporaneous corrosion, infiltration backflow dolomitization, packing, and rupturing. The porosity of reservoirs was originally 10%–30%, decreased to 0–6% due to seawater cementation, rose back to 5%–15% owing to penecontemporaneous corrosion, and finally declined to 2%–6% as a result of crystalline dolomites and calcites packing. The above methodology for the restoration of dolomitization and porosity evolution may be helpful for the restoration of porosity evolution in other basins or series of strata.

关键词： U-Pb dating Ordos Basin Ordovician Majiagou Formation diagenesis dolomitization porosity evolution

基于转录组学分析酿酒酵母PY01高密度培养的氧化胁迫应答机制

在线全文

学校读者我要写书评

暂无评论

中国食品学报 2024年第3期24卷 27-35页

作者：沈东旭翁佩芳吴祖芳刘亚楠燕囯梁宁波大学食品与药学学院浙江宁波315211 中国农业大学食品科学与营养工程学院北京100083

为探究酿酒酵母PY01高密度培养过程中响应氧化胁迫的机制,对酿酒酵母PY01氧化处理(6 mmol/L H_(2)O_(2))2 h后进行转录组学分析。结果表明:共鉴定出393个差异表达基因(DEGs);基于GO注释与KEGG富集分析,已鉴定的DEGs参与了代谢(如氨基酸... 详细信息

为探究酿酒酵母PY01高密度培养过程中响应氧化胁迫的机制,对酿酒酵母PY01氧化处理(6 mmol/L H_(2)O_(2))2 h后进行转录组学分析。结果表明:共鉴定出393个差异表达基因(DEGs);基于GO注释与KEGG富集分析,已鉴定的DEGs参与了代谢(如氨基酸代谢、碳水化合物代谢和能量代谢等)、遗传信息和细胞过程(过氧化物酶体)等通路。在氧化胁迫下,酵母菌通过增强一些抗氧化酶,如SOD2、SRX1等来清除ROS;酵母菌还通过增强糖酵解和TCA循环产生更多的能量,以适应氧化胁迫、修复损伤的蛋白质以及DNA或维持金属离子的转运。与此同时,还上调了与一般应激反应相关的分子伴侣和蛋白水解酶。这表明酿酒酵母PY01响应氧化胁迫的过程,是一个复杂的综合调控网络。酿酒酵母PY01应对氧化应激机制的发现,为设计酵母菌高效培养的控制策略,提高菌株的抗逆性和促进现代果酒等发酵工业及其它生物制品生产中利用活性酵母菌奠定了理论基础。

关键词：酿酒酵母PY01 发酵氧化胁迫转录组学机制

从个体转型到机构转向:欧盟职业教育教师培训的经验与启示

在线全文

学校读者我要写书评

暂无评论

教育学术月刊 2024年第3期 32-40页

作者：陈衍张易宁吴东旭浙江工业大学浙江杭州310023 浙江工业大学职业技术教育研究所浙江杭州310023 浙江工业大学长三角产教融合与职业教育发展研究院浙江杭州310023

全球教育改革浪潮推动了职业教育教师角色转变,因此,欧盟发布诸多职业教育教师培训相关文件。欧盟教师教育培训以校企合作为主要培训模式,注重绿色与数字技能培训,并由专门机构保障职教教师培训稳定、顺利地开展。欧盟的实践经验为我国... 详细信息

全球教育改革浪潮推动了职业教育教师角色转变,因此,欧盟发布诸多职业教育教师培训相关文件。欧盟教师教育培训以校企合作为主要培训模式,注重绿色与数字技能培训,并由专门机构保障职教教师培训稳定、顺利地开展。欧盟的实践经验为我国未来职业教育教师培训提供了启示:在职教教师培训机构设置方面,由大学提供更为专业的培训师与培训场所;在多方合作方面,不仅需要推进校企合作,还要跨地域、跨国家进行教师流动培训;在培训内容方面,职教教师不仅要学习专业知识,也要学习数字技能与学生心理发展方面的知识,并且在实际教学过程中熟练应用,以应对时代发展对职教教师提出的更高要求。

关键词：职业教育教师培训欧盟